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Acta Orthopaedica Volume 88, 2017 - Issue 4
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Articles

Metastatic spinal cord compression as the first sign of malignancy

Outcome after surgery in 69 patients

Johan WänmanDepartments of Surgical and Perioperative Sciences (Orthopedics), Umeå University, Umeå, Sweden.;
,
Pawel GrabowskiDepartments of Surgical and Perioperative Sciences (Orthopedics), Umeå University, Umeå, Sweden.;
,
Helena NyströmDepartments of Community Medicine and Rehabilitation (Geriatrics), Umeå University, Umeå, Sweden.;
,
Patrik GustafssonDepartments of Surgical and Perioperative Sciences (Orthopedics), Umeå University, Umeå, Sweden.;
,
Anders BerghDepartments of Medical Biosciences (Pathology), Umeå University, Umeå, Sweden.;
,
Anders WidmarkDepartments of Radiation Sciences (Oncology), Umeå University, Umeå, Sweden.
&
Sead CrnalicDepartments of Surgical and Perioperative Sciences (Orthopedics), Umeå University, Umeå, Sweden.; Correspondence[email protected]
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Pages 457-462 | Received 20 Oct 2016, Accepted 20 Feb 2017, Published online: 11 May 2017

  • Aizenberg M R, Fox B D, Suki D, McCutcheon I E, Rao G, Rhines L D. Surgical management of unknown primary tumors metastatic to the spine. J Neurosurg Spine 2012; 16: 86–92.
  • Chaichana K L, Pendleton C, Sciubba D, Wolinsky J P, Gokaslan Z. Outcome following decompressive surgery for different histological types of metastatic tumors causing epidural spinal cord compression. J Neurosurg Spine 2009; 11: 56–63.
  • Cole J S, Patchell R A. Metastatic epidural spinal cord compression. Lancet Neurol 2008; 7: 459–66.
  • Crnalic S, Hildingsson C, Wikstrom P, Bergh A, Löfvenberg R, Widmark A. Outcome after surgery for metastatic spinal cord compression in 54 patients with prostate cancer. Acta Orthop 2011; 83(1): 80–6.
  • Crnalic S, Löfvenberg R, Bergh A, Widmark A, Hildingsson C. Predicting survival for surgery of metastatic spinal cord compression in prostate cancer: a new score. Spine 2012; 37: 2168–76.
  • Crnalic S, Hildingsson C, Bergh A, Widmark A, Svensson O, Löfvenberg R. Early diagnosis and treatment is crucial for neurological recovery after surgery for metastatic spinal cord compression in prostate cancer. Acta Oncol 2013; 52: 809–15.
  • Enkaoua E A, Doursounian L, Chatellier G, Mabesoone F, Aimard T, Saillant G. Vertebral metastases – a critical appreciation of the preoperative prognostic Tokuhashi score in a series of 71 cases. Spine 1997; 22: 2293–8.
  • Fehlings M G, Nater A, Tetreault L, Kopjar B, Arnold P, Dekutoski M, Finkelstein J, Fisher C, France J, Gokaslan Z, Massicotte E, Rhines L, Rose P, Sahgal A, Schuster J, Vaccaro A. Survival and clinical outcomes in surgically treated patients with metastatic epidural spinal cord compression: results of the prospective multicenter AOSpine study. J Clin Oncol 2016; 34: 268–76.
  • Finkelstein J A, Zaveri G, Wai E, Vidar M, Kreder H, Chow E. A population-based study of surgery for spinal metastases: survival rates and complications. J Bone Joint Surg (Br) 2003; 85: 1045–50.
  • George, R, Jeba J, Ramkumar G, Chacko A G, Leng M, Tharyan P. Interventions for the treatment of metastatic extradural spinal cord compression in adults. Cochrane Database SystRev 2015; 9: p. CD006716
  • Helweg-Larsen S, Sorensen P, Kreiner S. Prognostic factors in metastatic spinal cord compression: a prospective study using multivariate analysis of variables influencing survival and gait function in 153 patients. Int J Radiat Oncol Biol Phys 2000; 46: 1163–9.
  • Huddart R A, Rajan B, Law M, Meyer L, Dearnaley D P. Spinal cord compression in prostate cancer: treatment outcome and prognostic factors. Radiother Oncol 1997; 44(3): 229–36.
  • Iizuka Y, Iizuka H, Tsutsumi S, Nakagawa Y, Nakajima T, Sorimachi Y, Ara T, Nishinome M, Seki T, Takagishi K. Diagnosis of a previously unidentified primary site in patients with spinal metastasis: diagnostic usefulness of laboratory analysis, CT scanning and CT-guided biopsy. Eur Spine J 2009; 18: 1431–5.
  • Jansson K A, Bauer H C. Survival, complications and outcome in 282 patients operated for neurological deficit due to thoracic or lumbar spinal metastases. Eur Spine J 2006; 15(2): 196–202.
  • Klimo P Jr, Thompson C J, Kestle J R, Schmidt MH . A meta-analysis of surgery versus conventional radiotherapy for the treatment of metastatic spinal epidural disease. Neuro Oncol 2005; 7(1): 64–76.
  • Lee C H, Kwon J W, Lee J, Hyun S J, Kim K J, Jahng T A, Kim H J. Direct decompressive surgery followed by radiotherapy versus radiotherapy alone for metastatic epidural spinal cord compression: a meta-analysis. Spine 2014; 39(9): E587–E592.
  • Loblaw D A, Laperriere N J, Mackillop W J. A population-based study of malignant spinal cord compression in Ontario. Clin Oncol (R Coll Radiol) 2003; 15(4): 211–17.
  • Rades D, Fehlauer F, Veninga T, Stalpers L J A, Basic H, Hoskin P J, Rudat V, Karstens J H, Schild S E, Dunst J. Functional outcome and survival after radiotherapy of metastatic spinal cord compression in patients with cancer of unknown primary. Int J Radiat Oncol Biol Phys 2007; 67: 532–7.
  • Schiff D, O’Neill B P, Suman V J. Spinal epidural metastasis as the initial manifestation of malignancy. Neurology 1997; 49: 452–6.
  • Takagi T, Katagiri H, Kim Y, Suehara Y, Kubota D, Akaike K, Ishii M, Mukaihara K, Okubo T, Murata H, Takahashi M, Kaneko K, Saito T. Skeletal metastasis of unknown primary origin at the initial visit: A retrospective analysis of 286 cases. PlosOne DO: 2015: 10.1471
  • Quraishi N A, Ramoutar D, Manoharan S R, Spencer A, Arealis G, Edwards K L, Boszczyk BM . Metastatic spinal cord compression as a result of the unknown primary tumor. Eur Spine J 2014; 23: 1502–7.
  • White B D, Stirling A J, Paterson E, Asquith-Coe K, Melder A. Diagnosis and management of patients at risk of or with metastatic spinal cord compression: summary of NICE guidance. BMJ 2008; 337: a2538.

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