An overview of nanofiber-based antibacterial drug design

References

• Demain AL, Sanchez S. Microbial drug discovery: 80 years of progress. J Antibiot (Tokyo). 2009;62:5–16.
   PubMed Web of Science ®Google Scholar
• Berendonk TU, Manaia CM, Merlin C, et al. Tackling antibiotic resistance: the environmental framework. Nat Rev Microbiol. 2015;13:310–317.
   PubMed Web of Science ®Google Scholar
• Bos J, Zhang Q, Vyawahare S, et al. Emergence of antibiotic resistance from multinucleated bacterial filaments. Proc Natl Acad Sci. 2015;112:178–183.
   PubMed Web of Science ®Google Scholar
• Chang -H-H, Cohen T, Grad YH, et al. Origin and proliferation of multiple-drug resistance in bacterial pathogens. Microbiol Mol Biol Rev. 2015;79:101–116.
   PubMed Web of Science ®Google Scholar
• De Faria AF, Perreault F, Shaulsky E, et al. Antimicrobial electrospun biopolymer nanofiber mats functionalized with graphene oxide–silver nanocomposites. ACS Appl Mater Interfaces. 2015;7:12751–12759.
   PubMed Web of Science ®Google Scholar
• Chmielewski R, Frank J. Biofilm formation and control in food processing facilities. Compr Rev Food Sci Food Saf. 2003;2:22–32.
   PubMedGoogle Scholar
• Romero D, Kolter R., Will biofilm disassembly agents make it to market? Trends Microbiol. 2011;19:304–306.
   PubMed Web of Science ®Google Scholar
• Elimelech M, Phillip WA. The future of seawater desalination: energy, technology, and the environment. Science. 2011;333:712–717.
   PubMed Web of Science ®Google Scholar
• Bryers JD. Medical biofilms. Biotechnol Bioeng. 2008;100:1–18.
   PubMed Web of Science ®Google Scholar
• Marano S, Barker SA, Raimi-Abraham BT, et al. Development of micro-fibrous solid dispersions of poorly water-soluble drugs in sucrose using temperature-controlled centrifugal spinning. Eur J Pharm Biopharm. 2016;103(2016):84–94.
   PubMed Web of Science ®Google Scholar
• Helmlinger J, Sengstock C, Groß-Heitfeld C, et al. Silver nanoparticles with different size and shape: equal cytotoxicity, but different antibacterial effects. RSC Adv. 2016;6:18490–18501.
   Web of Science ®Google Scholar
• Tang Q, Liu J, Shrestha LK, et al. Antibacterial effect of silver-incorporated flake-shell nanoparticles under dual-modality. ACS Appl Mater Interfaces. 2016;8:18922−18929.
   PubMed Web of Science ®Google Scholar
• Cui H, Li W, Li C, et al. Liposome containing cinnamon oil with antibacterial activity against methicillin-resistant Staphylococcus aureus biofilm. Biofouling. 2016;32:215–225.
   PubMed Web of Science ®Google Scholar
• Worley BV Structure-activity characterization of nitric oxide-releasing dendrimers as dual-action antibacterial agents: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL; 2016.
   Google Scholar
• Chung BG, Kang L, Khademhosseini A. Micro-and nanoscale technologies for tissue engineering and drug discovery applications. Expert Opin Drug Discov. 2007;2:1653–1668.
   PubMed Web of Science ®Google Scholar
• Sari E, Tunc-Sarisozen Y, Mutlu H, et al. ICAM-1 targeted catalase encapsulated PLGA-b-PEG nanoparticles against vascular oxidative stress. J Microencapsul. 2015;32:687–698.
   PubMed Web of Science ®Google Scholar
• Ulubayram K, Calamak S, Shahbazi R, et al. Nanofibers based antibacterial drug design, delivery and applications. Curr Pharm Des. 2015;21:1930–1943.
   PubMed Web of Science ®Google Scholar
• Gopiraman M, Jatoi AW, Hiromichi S, et al. Silver coated anionic cellulose nanofiber composites for an efficient antimicrobial activity. Carbohydr Polym. 2016;149:51–59.
   PubMed Web of Science ®Google Scholar
• Abdel-Mohsen A, Jancar J, Massoud D, et al. Novel chitin/chitosan-glucan wound dressing: isolation, characterization, antibacterial activity and wound healing properties. Int J Pharm. 2016;510:86–99.
   PubMed Web of Science ®Google Scholar
• Lim TH, Lee SH, Yeo SY. Highly conductive polymer/metal/carbon nanotube composite fiber prepared by the melt-spinning process. Textile Res J. 2016;0040517516632481.
   Google Scholar
• Poongodi G, Anandan P, Kumar RM, et al. Studies on visible light photocatalytic and antibacterial activities of nanostructured cobalt doped ZnO thin films prepared by sol–gel spin coating method. Spectrochimica Acta A: Mol Biomol Spectrosc. 2015;148:237–243.
   PubMed Web of Science ®Google Scholar
• Tran T, Hernandez M, Patel D, et al. Temperature and pH responsive microfibers for controllable and variable ibuprofen delivery. Adv Mater Sci Eng. 2015; Article ID 180187:6.
   Web of Science ®Google Scholar
• Molnar K, Nagy ZK. Corona-electrospinning: needleless method for high-throughput continuous nanofiber production. Eur Polym J. 2016;74:279–286.
   Web of Science ®Google Scholar
• Rieger KA, Birch NP, Schiffman JD. Designing electrospun nanofiber mats to promote wound healing–a review. J Mater Chem B. 2013;1:4531–4541.
   PubMed Web of Science ®Google Scholar
• Yu D-G, Li X-Y, Wang X, et al. Nanofibers fabricated using triaxial electrospinning as zero order drug delivery systems. ACS Appl Mater Interfaces. 2015;7:18891–18897.
   PubMed Web of Science ®Google Scholar
• Abrigo M, Kingshott P, McArthur SL. Bacterial response to different surface chemistries fabricated by plasma polymerization on electrospun nanofibers. Biointerphases. 2015;10:04A301.
   Google Scholar
• Saini S, Belgacem MN, Salon M-CB, et al. Non leaching biomimetic antimicrobial surfaces via surface functionalisation of cellulose nanofibers with aminosilane. Cellulose. 2016;23:795–810.
   Web of Science ®Google Scholar
• Gilchrist SE, Lange D, Letchford K, et al. Fusidic acid and rifampicin co-loaded PLGA nanofibers for the prevention of orthopedic implant associated infections. J Control Release. 2013;170:64–73.
   PubMed Web of Science ®Google Scholar
• Sathish Kumar Y, Unnithan AR, Sen D, et al. Microgravity biosynthesized penicillin loaded electrospun polyurethane–dextran nanofibrous mats for biomedical applications. Colloids Surf A Physicochem Eng Asp. 2015;477:77–83.
   Web of Science ®Google Scholar
• Cai N, Li C, Han C, et al. Tailoring mechanical and antibacterial properties of chitosan/gelatin nanofiber membranes with Fe3O4 nanoparticles for potential wound dressing application. Appl Surf Sci. 2016;369:492–500.
   Web of Science ®Google Scholar
• Ruckh TT, Oldinski RA, Carroll DA, et al. Antimicrobial effects of nanofiber poly(caprolactone) tissue scaffolds releasing rifampicin. J Mater Sci Mater Med. 2012;23:1411–1420.
   PubMed Web of Science ®Google Scholar
• Wang C, Tong SN, Tse YH, et al. Conventional electrospinning vs. emulsion electrospinning: a comparative study on the development of nanofibrous drug/biomolecule delivery vehicles. Switzerland: Trans Tech Publications; 2012.
   Google Scholar
• Tauber S, Fuerst R, Davis K, et al. Drug delivery system and methods of use. Google Patents. 2013. Patent no: US 8,361,492 B2.
   Google Scholar
• Jung WK, Koo HC, Kim KW, et al. Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl Environ Microbiol. 2008;74:2171–2178.
   PubMed Web of Science ®Google Scholar
• Rieger KA, Cho HJ, Yeung HF, et al. Antimicrobial activity of silver ions released from zeolites immobilized on cellulose nanofiber mats. ACS Appl Mater Interfaces. 2016;8:3032–3040.
   PubMed Web of Science ®Google Scholar
• Calamak S, Aksoy EA, Erdogdu C, et al. Silver nanoparticle containing silk fibroin bionanotextiles. J Nanoparticle Res. 2015;17:1–9.
   Web of Science ®Google Scholar
• Liu Y, Liu Y, Liao N, et al. Fabrication and durable antibacterial properties of electrospun chitosan nanofibers with silver nanoparticles. Int J Biol Macromol. 2015;79:638–643.
   PubMed Web of Science ®Google Scholar
• Calamak S, Aksoy EA, Ertas N, et al. Ag/silk fibroin nanofibers: effect of fibroin morphology on Ag+ release and antibacterial activity. Eur Polym J. 2015;67:99–112.
   Web of Science ®Google Scholar
• Hwang SH, Song J, Jung Y, et al. Electrospun ZnO/TiO2 composite nanofibers as a bactericidal agent. Chem Commun (Camb). 2011;47:9164–9166.
   PubMed Web of Science ®Google Scholar
• Das B, Mandal M, Upadhyay A, et al. N. Bio-based hyperbranched polyurethane/Fe3O4 nanocomposites: smart antibacterial biomaterials for biomedical devices and implants. Biomed Mater. 2013;8:035003.
   Google Scholar
• Gultekinoglu M, Sarisozen YT, Erdogdu C, et al. Designing of dynamic polyethyleneimine (PEI) brushes on polyurethane (PU) ureteral stents to prevent infections. Acta Biomater. 2015;21:44–54.
   PubMed Web of Science ®Google Scholar
• Gultekinoglu M, Oh YJ, Hinterdorfer P, et al. Nanoscale characteristics of antibacterial cationic polymeric brushes and single bacterium interactions probed by force microscopy. RSC Adv. 2016;6:17092–17099.
   Web of Science ®Google Scholar
• Özcan İ, Abacı Ö, Uztan AH, et al. Enhanced topical delivery of terbinafine hydrochloride with chitosan hydrogels. AAPS Pharmscitech. 2009;10:1024–1031.
   PubMed Web of Science ®Google Scholar
• Çalamak S, Erdoğdu C, Özalp M, et al. Silk fibroin based antibacterial bionanotextiles as wound dressing materials. Mater Sci Eng C. 2014;43:11–20.
   PubMed Web of Science ®Google Scholar
• Croisier F, Sibret P, Dupont-Gillain CC, et al. Chitosan-coated electrospun nanofibers with antibacterial activity. J Mater Chem B. 2015;3:3508–3517.
   PubMed Web of Science ®Google Scholar
• Seyam A-FM, Hudson SM, Ibrahim HM, et al. Healing performance of wound dressing from cyanoethyl chitosan electrospun fibres. Indian J Fibre Text. 2012;37:205.
   Web of Science ®Google Scholar
• Coneski PN, Fulmer PA, Giles SL, et al. Lyotropic self-assembly in electrospun biocidal polyurethane nanofibers regulates antimicrobial efficacy. Polymer. 2014;55:495–504.
   Web of Science ®Google Scholar
• Vasantha VA, Zainul Rahim SZ, Jayaraman S, et al. Antibacterial, electrospun nanofibers of novel poly(sulfobetaine) and poly(sulfabetaine)s. J Mater Chem B. 2016;4:2731–2738.
   Web of Science ®Google Scholar
• Li X, Cai T, Chung TS. Anti-fouling behavior of hyperbranched polyglycerol-grafted poly(ether sulfone) hollow fiber membranes for osmotic power generation. Environ Sci Technol. 2014;48:9898–9907.
   PubMed Web of Science ®Google Scholar
• Zupančič Š, Sinha-Ray S, Sinha-Ray S, et al. Controlled release of ciprofloxacin from core–shell nanofibers with monolithic or blended core. Mol Pharm. 2016;13:1393–1404.
   PubMed Web of Science ®Google Scholar
• Malam Y, Loizidou M, Seifalian AM. Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer. Trends Pharmacol Sci. 2009;30:592–599.
   PubMed Web of Science ®Google Scholar
• Ranjbar-Mohammadi M, Zamani M, Prabhakaran MP, et al. Electrospinning of PLGA/gum tragacanth nanofibers containing tetracycline hydrochloride for periodontal regeneration. Mater Sci Eng C Mater Biol Appl. 2016;58:521–531.
   PubMed Web of Science ®Google Scholar
• Zhang J, Misra RD. Magnetic drug-targeting carrier encapsulated with thermosensitive smart polymer: core-shell nanoparticle carrier and drug release response. Acta Biomater. 2007;3:838–850.
   PubMed Web of Science ®Google Scholar
• Shen X, Yu D, Zhu L. Electrospun diclofenac sodium loaded Eudragit(R) L 100-55 nanofibers for colon-targeted drug delivery. Int J Pharm. 2011;408:200–207.
   PubMed Web of Science ®Google Scholar
• Yoo HS, Kim TG, Park TG. Surface-functionalized electrospun nanofibers for tissue engineering and drug delivery. Adv Drug Deliv Rev. 2009;61:1033–1042.
   PubMed Web of Science ®Google Scholar
• Wang C, Yan KW, Lin YD, et al. Biodegradable core/shell fibers by coaxial electrospinning: processing, fiber characterization, and its application in sustained drug release. Macromolecules. 2010;43:6389–6397.
   Web of Science ®Google Scholar
• Bolgen N, Vargel I, Korkusuz P, et al. In vivo performance of antibiotic embedded electrospun PCL membranes for prevention of abdominal adhesions. J Biomed Mater Res B-Applied Biomater. 2007;81B:530–543.
   Web of Science ®Google Scholar
• Wang S, Zheng F, Huang Y, et al. Encapsulation of amoxicillin within laponite-doped poly(lactic-co-glycolic acid) nanofibers: preparation, characterization, and antibacterial activity. ACS Appl Mater Interfaces. 2012;4:6393–6401.
   PubMed Web of Science ®Google Scholar
• Mohammadi MR, Rabbani S, Bahrami SH, et al. Antibacterial performance and in vivo diabetic wound healing of curcumin loaded gum tragacanth/poly (ε-caprolactone) electrospun nanofibers. Mater Sci Eng C. 2016;69:1183–1191.
   PubMed Web of Science ®Google Scholar
• Ahmed SM, Ahmed H, Tian C, et al. Whey protein concentrate doped electrospun poly (epsilon-caprolactone) fibers for antibiotic release improvement. Colloids Surf B Biointerfaces. 2016;143:371–381.
   PubMed Web of Science ®Google Scholar
• Qi H, Hu P, Xu J, et al. Encapsulation of drug reservoirs in fibers by emulsion electrospinning: morphology characterization and preliminary release assessment. Biomacromolecules. 2006;7:2327–2330.
   PubMed Web of Science ®Google Scholar
• Xu X, Chen X, Ma P, et al. The release behavior of doxorubicin hydrochloride from medicated fibers prepared by emulsion-electrospinning. Eur J Pharm Biopharm. 2008;70:165–170.
   PubMed Web of Science ®Google Scholar
• Zheng F, Wang S, Wen S, et al. Characterization and antibacterial activity of amoxicillin-loaded electrospun nano-hydroxyapatite/poly(lactic-co-glycolic acid) composite nanofibers. Biomaterials. 2013;34:1402–1412.
   PubMed Web of Science ®Google Scholar
• Moghe AK, Gupta BS. Co‐axial electrospinning for nanofiber structures: preparation and applications. Polymer Rev. 2008;48:353–377.
   Web of Science ®Google Scholar
• Qi R, Guo R, Shen M, et al. Electrospun poly(lactic-co-glycolic acid)/halloysite nanotube composite nanofibers for drug encapsulation and sustained release. J Mater Chem. 2010;20:10622–10629.
   Web of Science ®Google Scholar
• Zhang J-F, Yang D-Z, Xu F, et al. Electrospun core−shell structure nanofibers from homogeneous solution of poly(ethylene oxide)/chitosan. Macromolecules. 2009;42:5278–5284.
   Web of Science ®Google Scholar
• Sun ZC, Zussman E, Yarin AL, et al. Compound core-shell polymer nanofibers by co-electrospinning. Adv Mater. 2003;15:1929.
   Web of Science ®Google Scholar
• Zhuo HT, Hu JL, Chen SJ. Coaxial electrospun polyurethane core-shell nanofibers for shape memory and antibacterial nanomaterials. Express Polym Lett. 2011;5:182–187.
   Web of Science ®Google Scholar
• Qi R, Guo R, Zheng F, et al. Controlled release and antibacterial activity of antibiotic-loaded electrospun halloysite/poly(lactic-co-glycolic acid) composite nanofibers. Colloids Surf B Biointerfaces. 2013;110:148–155.
   PubMed Web of Science ®Google Scholar
• Su Y, Su Q, Liu W, et al. Dual-drug encapsulation and release from core-shell nanofibers. J Biomater Sci Polym Ed. 2012;23:861–871.
   PubMed Web of Science ®Google Scholar
• Qian W, Yu DG, Li Y, et al. Dual drug release electrospun core-shell nanofibers with tunable dose in the second phase. Int J Mol Sci. 2014;15:774–786.
   PubMed Web of Science ®Google Scholar
• Yarin AL. Coaxial electrospinning and emulsion electrospinning of core-shell fibers. Polym Advan Technol. 2011;22:310–317.
   Web of Science ®Google Scholar
• Wang SG, Jiang X, Chen PC, et al. Preparation of coaxial-electrospun poly[bis(p-methylphenoxy)]phosphazene nanofiber membrane for enzyme immobilization. Int J Mol Sci. 2012;13:14136–14148.
   PubMed Web of Science ®Google Scholar
• Loscertales IG, Barrero A, Guerrero I, et al. Micro/nano encapsulation via electrified coaxial liquid jets. Science. 2002;295:1695–1698.
   PubMed Web of Science ®Google Scholar
• Su Y, Su Q, Liu W, et al. Controlled release of bone morphogenetic protein 2 and dexamethasone loaded in core-shell PLLACL-collagen fibers for use in bone tissue engineering. Acta Biomater. 2012;8:763–771.
   PubMed Web of Science ®Google Scholar
• Yu DG, Zhou J, Chatterton NP, et al. Polyacrylonitrile nanofibers coated with silver nanoparticles using a modified coaxial electrospinning process. Int J Nanomedicine. 2012;7:5725–5732. Epub 2012/11/21
   PubMed Web of Science ®Google Scholar
• Yu D-G, Li X-Y, Wang X, et al. Zero-order drug release cellulose acetate nanofibers prepared using coaxial electrospinning. Cellulose. 2013;20:379–389.
   Web of Science ®Google Scholar
• Yu D-G, Williams GR, Wang X, et al. Dual drug release nanocomposites prepared using a combination of electrospraying and electrospinning. RSC Adv. 2013;3:4652–4658.
   Web of Science ®Google Scholar
• Xie J, Mao H, Yu D-G, et al. Stable coated polyvinylpyrrolidone nanofibers prepared using modified coaxial electrospinning. Fiber Polym. 2014;15:78–83.
   Web of Science ®Google Scholar
• Sohrabi A, Shaibani PM, Etayash H, et al. Sustained drug release and antibacterial activity of ampicillin incorporated poly(methyl methacrylate)–nylon6 core/shell nanofibers. Polymer. 2013;54:2699–2705.
   Web of Science ®Google Scholar
• Gupta P, Wilkes GL. Some investigations on the fiber formation by utilizing a side-by-side bicomponent electrospinning approach. Polymer. 2003;44:6353–6359.
   Web of Science ®Google Scholar
• Pehlivan SB, Yavuz B, Çalamak S, et al. Preparation and in vitro/in vivo evaluation of cyclosporin A‐loaded nanodecorated ocular implants for subconjunctival application. J Pharm Sci. 2015;104:1709–1720.
   PubMed Web of Science ®Google Scholar
• Yavuz B, Bozdağ Pehlivan S, Kaffashi A, et al. In vivo tissue distribution and efficacy studies for cyclosporin A loaded nano-decorated subconjunctival implants. Drug Deliv. 2016;23:3279-3284.
   PubMed Web of Science ®Google Scholar
• Weng L, Xie J. Smart electrospun nanofibers for controlled drug release: recent advances and new perspectives. Curr Pharm Des. 2015;21:1944–1959.
   PubMed Web of Science ®Google Scholar
• Yang C, Yu D-G, Pan D, et al. Electrospun pH-sensitive core–shell polymer nanocomposites fabricated using a tri-axial process. Acta Biomater. 2016;35:77–86.
   PubMed Web of Science ®Google Scholar
• Demirci S, Celebioglu A, Aytac Z, et al. pH-responsive nanofibers with controlled drug release properties. Polym Chem. 2014;5:2050–2056.
   Web of Science ®Google Scholar
• Azarbayjani AF, Venugopal JR, Ramakrishna S, et al. Smart polymeric nanofibers for topical delivery of levothyroxine. J Pharm Pharm Sci. 2010;13:400–410.
   PubMed Web of Science ®Google Scholar
• Elashnikov R, Lyutakov O, Ulbrich P, et al. Light-activated polymethylmethacrylate nanofibers with antibacterial activity. Mater Sci Eng C. 2016;64:229–235.
   PubMed Web of Science ®Google Scholar
• Nakielski P, Kowalczyk T, Kowalewski TA. Modeling drug release from materials based on electrospun nanofibers. Rotterdam; 2013.
   Google Scholar
• Shaikh HK, Kshirsagar R, Patil S. Mathematical models for drug release characterization: a review. Wjpps. 2015;4:324–338.
   Google Scholar
• El-Naggar ME, El-Rafie M, El-Sheikh M, et al. Synthesis, characterization, release kinetics and toxicity profile of drug-loaded starch nanoparticles. Int J Biol Macromol. 2015;81:718–729.
   PubMed Web of Science ®Google Scholar
• Barzegar-Jalali M, Adibkia K, Valizadeh H, et al. Kinetic analysis of drug release from nanoparticles. J Pharm Pharm Sci. 2008;11:167–177.
   PubMed Web of Science ®Google Scholar
• Blanco E, Shen H, Ferrari M. Principles of nanoparticle design for overcoming biological barriers to drug delivery. Nat Biotechnol. 2015;33:941–951.
   PubMed Web of Science ®Google Scholar
• Mazza M, Notman R, Anwar J, et al. Nanofiber-based delivery of therapeutic peptides to the brain. ACS Nano. 2013;7:1016–1026.
   PubMed Web of Science ®Google Scholar
• Kamble RN, Gaikwad S, Maske A, et al. Fabrication of electrospun nanofibres of BCS II drug for enhanced dissolution and permeation across skin. J Adv Res. 2016;7:483–489.
   PubMed Web of Science ®Google Scholar
• Sebe I, Szabó P, Kállai-Szabó B, et al. Incorporating small molecules or biologics into nanofibers for optimized drug release: a review. Int J Pharm. 2015;494:516–530.
   PubMed Web of Science ®Google Scholar
• Andrady AL. Science and technology of polymer nanofibers. Hoboken, New Jersey: John Wiley & Sons; 2008.
   Google Scholar
• Goonoo N, Bhaw-Luximon A, Jhurry D. Drug loading and release from electrospun biodegradable nanofibers. J Biomed Nanotechnol. 2014;10:2173–2199.
   PubMed Web of Science ®Google Scholar
• Kim K, Luu YK, Chang C, et al. Incorporation and controlled release of a hydrophilic antibiotic using poly (lactide-co-glycolide)-based electrospun nanofibrous scaffolds. J Control Release. 2004;98:47–56.
   PubMed Web of Science ®Google Scholar
• Rezaei A, Nasirpour A, Tavanai H, et al. A study on the release kinetics and mechanisms of vanillin incorporated in almond gum/polyvinyl alcohol composite nanofibers in different aqueous food simulants and simulated saliva. Flavour Fragr J. 2016;31:442–447.
   Web of Science ®Google Scholar
• Vemula VR, Lagishetty V, Lingala S. Solubility enhancement techniques. Ijpsrr. 2010;5:41–51.
   Google Scholar
• Chou S-F, Carson D, Woodrow KA. Current strategies for sustaining drug release from electrospun nanofibers. J Control Release. 2015;220:584–591.
   PubMed Web of Science ®Google Scholar
• Yu D, Wang X, Li X, et al. Electrospun biphasic drug release polyvinylpyrrolidone/ethyl cellulose core/sheath nanofibers. Acta Biomater. 2013;9:5665–5672.
   PubMed Web of Science ®Google Scholar
• Laha A, Yadav S, Majumdar S, et al. In-vitro release study of hydrophobic drug using electrospun cross-linked gelatin nanofibers. Biochem Eng J. 2016;105:481–488.
   Web of Science ®Google Scholar
• Gholipour-Kanani A, Bahrami SH, Joghataie MT, et al. Tissue engineered poly (caprolactone)-chitosan-poly (vinyl alcohol) nanofibrous scaffolds for burn and cutting wound healing. IET Nanobiotechnol. 2014;8:123–131.
   PubMed Web of Science ®Google Scholar
• Feng S, Nie L, Zou P, et al. Effects of drug and polymer molecular weight on drug release from PLGA‐mPEG microspheres. J Appl Polym Sci. 2015;132:6:41431(1-8).
   Web of Science ®Google Scholar
• Wang J, Vermerris W. Antimicrobial nanomaterials derived from natural products – a review. Materials. 2016;9:255.
   PubMed Web of Science ®Google Scholar
• Rathinamoorthy R. Nanofiber for drug delivery system – principle and application. Pak Text J. 2012;61:45–48.
   Google Scholar
• Paaver U, Laidmäe I, Santos HA, et al. Development of a novel electrospun nanofibrous delivery system for poorly water-soluble β-sitosterol. Asian J Pharm Sci. 2016;11:500–506.
   Web of Science ®Google Scholar
• Sultanova Z, Kaleli G, Kabay G, et al. Controlled release of a hydrophilic drug from coaxially electrospun polycaprolactone nanofibers. Int J Pharm. 2016;505:133–138.
   PubMed Web of Science ®Google Scholar
• Wen H-F, Yang C, Yu D-G, et al. Electrospun zein nanoribbons for treatment of lead-contained wastewater. Chem Eng J. 2016;290:263–272.
   Web of Science ®Google Scholar
• Yu D-G, Yang C, Jin M, et al. Medicated Janus fibers fabricated using a Teflon-coated side-by-side spinneret. Colloids Surf B Biointerfaces. 2016;138:110–116.
   PubMed Web of Science ®Google Scholar
• Taneri F, Ozcan I, Guneri T. In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-β-cyclodextrin. Drug Delivery. 2010;17:152–157.
   PubMed Web of Science ®Google Scholar
• Ozcan I, Segura-Sanchez F, Bouchemal K, et al. Pegylation of poly (γ-benzyl-L-glutamate) nanoparticles is efficient for avoiding mononuclear phagocyte system capture in rats. Int J Nanomed. 2010;5:1103–1111.
   PubMed Web of Science ®Google Scholar
• Aytac Z, Dogan SY, Tekinay T, et al. Release and antibacterial activity of allyl isothiocyanate/β-cyclodextrin complex encapsulated in electrospun nanofibers. Colloids Surf B Biointerfaces. 2014;120:125–131.
   PubMed Web of Science ®Google Scholar
• Zhang Q, Li X, Ren Z, et al. Synthesis of CaTiO3 nanofibers with controllable drug‐release kinetics. Eur J Inorg Chem. 2015;2015:4532–4538.
   PubMed Web of Science ®Google Scholar
• Hrib J, Sirc J, Hobzova R, et al. Nanofibers for drug delivery – incorporation and release of model molecules, influence of molecular weight and polymer structure. Beilstein J Nanotechnol. 2015;6:1939–1945.
   PubMed Web of Science ®Google Scholar
• Samprasit W, Rojanarata T, Akkaramongkolporn P, et al. Fabrication and in vitro/in vivo performance of mucoadhesive electrospun nanofiber mats containing α-mangostin. AAPS Pharmscitech. 2015;16:1140–1152.
   PubMed Web of Science ®Google Scholar