49
Views
0
CrossRef citations to date
0
Altmetric
Review

Clinical presentation of ischemic optic neuropathies

&
Pages 167-176 | Received 20 Apr 2023, Accepted 12 Jul 2023, Published online: 19 Jul 2023

References

  • Johnson LN, Arnold AC. Incidence of nonarteritic and arteritic anterior ischemic optic neuropathy. Population-based study in the state of Missouri and Los Angeles County, California. J Neuroophthalmol. 1994 Mar;14(1):38–44. doi: 10.1097/00041327-199403000-00011
  • Hattenhauer MG, Leavitt JA, Hodge DO, et al. Incidence of nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol. 1997 Jan;123(1):103–107.
  • Lee JY, Park KA, Oh SY, et al. Prevalence and incidence of non-arteritic anterior ischaemic optic neuropathy in South Korea: a nationwide population-based study. Br J Ophthalmol. 2018 Jul;102(7):936–941.
  • Swartz NG, Beck RW, Savino PJ, et al. Pain in anterior ischemic optic neuropathy. J Neuroophthalmol. 1995 Mar;15(1):9–10.
  • Arnold AC, Costa RM, Dumitrascu OM. The spectrum of optic disc ischemia in patients younger than 50 years (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2013 Sep;111:93–118.
  • Preechawat P, Bruce BB, Newman NJ, et al. Anterior ischemic optic neuropathy in patients younger than 50 years. Am J Ophthalmol. 2007 Dec;144(6):953–960.
  • Hamann S, Malmqvist L, Wegener M, et al. Young adults with anterior ischemic optic neuropathy: A multicenter optic disc drusen study. Am J Ophthalmol. 2020 Sep;217:174–181.
  • Miller NR, Arnold AC. Current concepts in the diagnosis, pathogenesis and management of nonarteritic anterior ischaemic optic neuropathy. Eye (Lond). 2015 Jan;29(1):65–79. doi: 10.1038/eye.2014.144
  • Dattilo M, Tian T, Peragallo JH, et al. Very poor visual acuity in non-arteritic anterior ischaemic optic neuropathy. Neuro-Ophthalmology. 2021;45(1):23–28. doi: 10.1080/01658107.2020.1785509
  • Pollack SC, Hubbe RH. Color vision in anterior ischemic optic neuropathy. Am J Ophthalmol Case Rep. 2020 Jul;19:100823. doi: 10.1016/j.ajoc.2020.100823
  • Beck RW, Savino PJ, Repka MX, et al. Optic disc structure in anterior ischemic optic neuropathy. Ophthalmol. 1984 Nov;91(11):1334–1337. doi: 10.1016/S0161-6420(84)34146-X
  • Beck RW, Servais GE, Hayreh SS. Anterior ischemic optic neuropathy. IX. Cup to disc ratio and its role in pathogenesis. Ophthalmol. 1987 Nov;94(11):1503–1508. doi: 10.1016/S0161-6420(87)33263-4
  • Burde RM. Optic disk risk factors for nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol. 1993 Dec;116(6):759–764. doi: 10.1016/S0002-9394(14)73478-6
  • Nagia L, Huisingh C, Johnstone J, et al. Peripapillary pachychoroid in nonarteritic anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci. 2016 Sep;57(11):4679–4685.
  • Fard MA, Abdi P, Kasaei A, et al. Peripapillary choroidal thickness in nonarteritic anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci. 2015 Mar 26:IOVS-14–15661. doi: 10.1167/iovs.14-15661
  • Pérez-Sarriegui A, Muñoz-Negrete FJ, Noval S, et al. Automated evaluation of choroidal thickness and minimum rim width thickness in nonarteritic anterior ischemic optic neuropathy. J Neuroophthalmol. 2018 Mar;38(1):7–12.
  • Girkin CA. Is nonarteritic ischemic optic neuropathy due to choroidal compression of the prelaminar neurovascular compartment of the optic nerve head? J Neuroophthalmol. 2018 Mar;38(1):1–3. doi: 10.1097/WNO.0000000000000628
  • Thompson AC, Bhatti MT, Gospe SM. Spectral-domain optical coherence tomography of the vitreopapillary interface in acute nonarteritic anterior ischemic optic neuropathy Am. J Ophthalmol. 2018Nov; 195: 199–208. 3rd. doi: 10.1016/j.ajo.2018.08.002.
  • Ischemic Optic Neuropathy Decompression Trial Research Group. Optic nerve decompression surgery for nonarteritic anterior ischemic optic neuropathy (NAION) is not effective and may be harmful. 1995 JAMA. Feb. 273(8):625–632. doi:10.1001/jama.273.8.625.
  • Hayreh SS, Zimmerman MB. Optic disc edema in non-arteritic anterior ischemic optic neuropathy. Graefes Arch Clin Exp Ophthalmol. 2007 Aug;245(8):1107–1121. doi: 10.1007/s00417-006-0494-0
  • Beck RW, Hayreh SS, Podhajsky PA, et al. Aspirin therapy in nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol. 1997 Feb;123(2):212–217.
  • Guyer DR, Miller NR, Auer CL, et al. The risk of cerebrovascular and cardiovascular disease in patients with anterior ischemic optic neuropathy. Arch Ophthalmol. 1985 Aug;103(8):1136–1142. doi: 10.1001/archopht.1985.01050080048018
  • Sawle GV, James CB, Russell RW. The natural history of nonarteritic anterior ischaemic optic neuropathy. J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):830–833. doi: 10.1136/jnnp.53.10.830
  • Egan RA, Arnold AC, Lee AG, et al. Should aspirin be prescribed to prevent recurrence in nonarteritic anterior ischemic optic neuropathy? J Neuroophthalmol. 2020 Sep;40(3):428–433.
  • Arnold AC, Hepler RS. Fluorescein angiography in acute nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol. 1994 Feb 15;117(2):222–230.
  • Arnold AC, Madr MA, Hepler RS. Fluorescein angiography in nonischemic optic disc edema. Arch Ophthalmol. 1996 Mar;114(3):293–298. doi: 10.1001/archopht.1996.01100130289011
  • Winter A, Chwalisz B. MRI characteristics of NMO, MOG and MS-related optic neuritis. Semin Ophthalmol. 2020 Nov;35(7–8):333–342. doi: 10.1080/08820538.2020.1866027
  • Campbell UB, Walker AM, Gaffney M, et al. Acute nonarteritic anterior ischemic optic neuropathy and exposure to phosphodiesterase type 5 inhibitors. J Sex Med. 2015 Jan;12(1):139–151.
  • Hayreh SS, Zimmerman MB. Incipient nonarteritic anterior ischemic optic neuropathy. Ophthalmol. 2007 Sep;114(9):1763–1772. doi: 10.1016/j.ophtha.2006.11.035
  • Sadda SR, Nee M, Miller NR, et al. Clinical spectrum of posterior ischemic optic neuropathy. Am J Ophthalmol. 2001 Nov;132(5):743–750.
  • McCulley TJ, Lam BL, Feuer WJ. Incidence of nonarteritic anterior ischemic optic neuropathy associated with cataract extraction. Ophthalmol. 2001 Jul;108(7):1275–1278. doi: 10.1016/S0161-6420(01)00631-5
  • McCulley TJ, Lam BL, Feuer WJ. Nonarteritic anterior ischemic optic neuropathy and surgery of the anterior segment: temporal relationship analysis. Am J Ophthalmol. 2003 Dec;136(6):1171–1172. 2003. doi: 10.1016/S0002-9394(03)00676-7
  • Lam BL, Jabaly-Habib H, Al-Sheikh N, et al. Risk of non-arteritic anterior ischaemic optic neuropathy (NAION) after cataract extraction in the fellow eye of patients with prior unilateral NAION. Br J Ophthalmol. 2007 May;91(5):585–587. doi: 10.1136/bjo.2006.0107276
  • Michaels DD, Zugsmith GS. Optic neuropathy following cataract extraction. Ann Ophthalmol. 1973 Mar;5(3):303–306.
  • Bhatti MT, Miller NR. Post-cataract surgery optic neuropathy: a chronological narrative review of the literature and speculation on pathogenesis. Curr Opin Ophthalmol. 2022 Nov 1;33(6):485–493.
  • Moradi A, Kanagalingam S, Diener-West M, et al. Post-cataract surgery optic neuropathy: Prevalence, incidence, temporal relationship, and fellow eye involvement. Am J Ophthalmol. 2017 Mar;175:183–193. doi: 10.1016/j.ajo.2016.10.008
  • Yang HK, Park SJ, Byun SJ, et al. Risk of nonarteritic anterior ischemic optic neuropathy after cataract surgery. Am J Ophthalmol. 2019 Nov;207:343–350.
  • McCulley TJ, Miller NR. Is cataract surgery a risk for developing nonarteritic anterior ischemic optic neuropathy? J Neuroophthalmol. 2021 Mar 1;41(1):119–125.
  • Rubin DS, Parakati I, Lee LA, et al. Perioperative visual loss in spine fusion surgery: Ischemic optic neuropathy in the United States from 1998 to 2012 in the Nationwide Inpatient Sample. Anesthesiology. 2016 Sep;125(3):457–464.
  • Lee LA, Roth S, Todd MM, et al. The postoperative visual loss study group. risk factors associated with ischemic optic neuropathy after spinal fusion surgery. Anesthesiology. 2012 Jan;116(1):15–24.
  • Kalyani SD, Miller NR, Dong LM, et al. Incidence of and risk factors for perioperative optic neuropathy after cardiac surgery. Ann Thorac Surg. 2004 Jul;78(1):34–37.
  • Rubin DS, Matsumoto MM, Moss HE, et al. Ischemic optic neuropathy in cardiac surgery: incidence and risk factors in the United States from the national inpatient sample 1998 to 2013. Anesthesiology. 2017 May;126(5):810–821.
  • Assawakawintip C, Nuttall GA, Garrity JA, et al. Incidence of ischemic optic neuropathy after cardiopulmonary bypass: 20-year experience. J Cardiothorac Vasc Anesth. 2021 Jan;35(1):35–38.
  • Gilbert ME, Savino PJ, Sergott RC. Anterior ischaemic optic neuropathy after rotator cuff surgery. Br J Ophthalmol. 2006 Feb;90(2):248–249. doi: 10.1136/bjo.2005.081455
  • Chan JW, JW Chan. Acute bilateral simultaneous PION after ectopic pregnancy-related haemorrhage. Eye (Lond). 2006 Jun;20(6):747–748. doi: 10.1038/sj.eye.6702010.
  • Yazgan S, Ayar O, Akdemir MO, et al. Simultaneous bilateral non-arteritic anterior ischaemic optic neuropathy and unilateral central retinal artery occlusion after hip prosthesis surgery. Neuro-Ophthalmology. 2014 Jun 27;38(5):257–259.
  • Marshall BK, Goel M, Pitha IF, et al. Sequential episodes of perioperative ischemic optic neuropathy after hip surgery. J Neuroophthalmol. 2014 Jun;34(2):165–168.
  • Chang S-H, Miller NR. The incidence of vision loss due to perioperative ischemic optic neuropathy associated with spine surgery. The Johns Hopkins Exp Spine. 2005 Jun 1;30(11):1299–1302.
  • Heitz JW, Audu PB. Asymmetric postoperative visual loss after spine surgery in the lateral decubitus position. Br J Anaesth. 2008 Sep;101(3):380–382. doi: 10.1093/bja/aen163
  • Eli IM, Kim RB, Kilburg C, et al. Postoperative posterior ischemic optic neuropathy after left far-lateral craniectomy for resection of craniocervical meningioma. World Neurosurg. 2018 Jun;114:339–343.
  • Kawasaki A, Purvin V. Recovery of postoperative visual loss following treatment of severe anaemia. Clin Exp Ophthalmol. 2006 Jul;34(5):497–499. doi: 10.1111/j.1442-9071.2006.01254.x
  • Al-Abdulla NA, Miller NR. Giant cell arteritis: An update on diagnosis and management. Comp Ophthalmol Update. 2002;3:155–166.
  • Ing EB, Miller NR, Nguyen A, et al. Neural network and logistic regression diagnostic prediction models for giant cell arteritis: development and validation. Clin Ophthalmol. 2019 Feb;13: 421–430. 10.2147/OPTH.S193460
  • Jeeva-Patel T, Kabanovski A, Margolin E. Transient monocular visual loss: When is it an emergency? J Emerg Med. 2021 Feb;60(2):192–196. doi: 10.1016/j.jemermed.2020.10.013
  • Donaldson L, Shemesh AA, Margolin EL. Two cases of segmental disc oedema and normal visual acuity in giant cell arteritis. Neuro-Ophthalmology. 2018 Jul;43(3):201–204. doi: 10.1080/01658107.2018.1490778
  • Pollock SC, Arnold AC, Miller NR. Vessels in full view. Preserved vascular clarity in acute arteritic anterior ischaemic optic neuropathy. Acta Ophthalmol. 2019 Nov;97(7):727–728. doi: 10.1111/aos.14202
  • SS Hayreh. Anterior ischaemic optic neuropathy. Differentiation of arteritic from non-arteritic type and its management. Eye (Lond). 1990;4(Pt 1):25–41. doi: 10.1038/eye.1990.4
  • Gaier ED, Gilbert AL, Cestari DM, et al. Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis. Br J Ophthalmol. 2018 Aug;102(8):1141–1146.
  • Liu TYA, Miller NR. Giant cell arteritis presenting as unilateral anterior ischemic optic neuropathy associated with bilateral optic nerve sheath enhancement on magnetic resonance imaging. J Neuroophthalmol. 2015 Dec;35(4):360–363. doi: 10.1097/WNO.0000000000000269
  • Remond P, Attyé A, Lecler A, et al. The central bright spot sign: A potential new MR imaging sign for the early diagnosis of anterior ischemic optic neuropathy due to giant cell arteritis. AJNR Am J Neuroradiol. 2017 Jul;38(7):1411–1415.
  • Emami S, Howarth D, Margolin E. Giant cell arteritis presenting as bilateral optic perineuritis in an African man. J Neuroophthalmol. 2021 Jun;41(2):e149–e152. doi: 10.1097/WNO.0000000000000951
  • Tseng AM, Bindiganavile SH, Bhat N, et al. Optic perineuritis distinguishing arteritic ischaemic from amiodarone-associated optic neuropathy. Neuro-Ophthalmology. 2020 Oct;45(5):329–333.
  • Danyel LA, Miszczuk M, Pietrock C, et al. Utility of standard diffusion-weighted magnetic resonance imaging for the identification of ischemic optic neuropathy in giant cell arteritis. Sci Rep. 2022 Oct;12(1):16553.
  • Hayreh SS, Podhajsky PA, Raman R, et al. Giant cell arteritis: validity and reliability of various diagnostic criteria. Am J Ophthalmol. 1997 Mar;123(3):285–296.
  • Parikh M, Miller NR, Lee AG, et al. Prevalence of a normal C-reactive protein with an elevated erythrocyte sedimentation rate in biopsy-proven giant cell arteritis. Ophthalmol. 2006 Oct;113(10):1842–1845.
  • Bley TA, Weiben O, Uhl M, et al. Assessment of the cranial involvement pattern of giant cell arteritis with 3T magnetic resonance imaging. Arthritis Rheum. 2005 Aug;52(8):2470–2477.
  • Markl M, Uhl M, Wieben O, et al. High resolution 3T MRI for the assessment of cervical and superficial cranial arteries in giant cell arteritis. J Magn Resons Imaging. 2006 Aug;24(2):423–427.
  • Siemonsen S, Brekenfeld C, Hoist B, et al. 3T MRI reveals extra- and intracranial involvement in giant cell arteritis. AJNR Am J Neuroradiol. 2015 Jan;36(1):91–97.
  • Lambrechts RA, Uyttenboogaart M, Drost G. A vertebral artery halo sign indicates giant cell arteritis affecting the posterior circulation of the brain. Lancet. 2021 Feb;397(10274):e6. doi: 10.1016/S0140-6736(21)00248-8
  • Goll C, Thormann M, Hofmüller W, et al. Feasibility study: 7 T MRI in giant cell arteritis. Graefes Arch Clin Exp Ophthalmol. 2016 Jun;254(6):1111–1116.
  • Conway R, Smyth AE, Kavanagh RG, et al. Diagnostic utility of computed tomographic angiography in giant-cell arteritis. Stroke. 2018 Sep;49(9):2233–2236.
  • Pattmöller M, Daas L, Viestenz A, et al. Ultrasound biomicroscopy in giant cell arteritis. Ophthalmologe. 2018 Feb;115(2):150–153.
  • Sommer F, Spörl E, Herber R, et al. Predictive value of positive temporal artery biopsies in patients with clinically suspected giant cell arteritis considering temporal artery ultrasound findings. Graefes Arch Clin Exp Ophthalmol. 2019 Oct;257(10):2279–2284.
  • Lyons HS, Quick V, Sinclair AJ, et al. A new era for giant cell arteritis. Eye (Lond). 2020 Jun;34(6):1013–1026.
  • Chrysidis S, Døhn UM, Terslev L, et al. Diagnostic accuracy of vascular ultrasound in patients with suspected giant cell arteritis (EUREKA): a prospective, multicentre, non-interventional, cohort study. Lancet Rheumatol. 2021 Oct;3(12):e865–873.
  • Hansen MS, Terslev L, Jensen MR, et al. Comparison of temporal artery ultrasound versus biopsy in the diagnosis of giant cell arteritis. Eye (Lond). 2023 Feb;37(2):344–349.
  • Dejaco C, Ramiro S, Duftner C, et al. EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice. Ann Rheum Dis. 2018 May;77(5):636–643.
  • Mackie SL, Dejaco C, Appenzeller S, et al. British society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis Rheumatology (Oxford). Rheumatology. 2020 Mar;59(3):e1–e23.
  • Mackie SL, Smith K, El Khoury L. Scienced by blinding: ultrasound for giant cell arteritis. Lancet Rheumatol. 2021 Oct;3(12):e824–e826. doi: 10.1016/S2665-9913(21)00311-8
  • Villager PM, Adler S, Kuchen S, et al. Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet. 2016 May;387(10031):1921–1927.
  • Guillevin L, Régent. Treating giant-cell arteritis: is IL-6 the cytokine to target? Lancet. 2016 May 7;387(10031):1882–1883. doi: 10.1016/S0140-6736(16)30183-0
  • Stone JH, Tuckwell K, Dimonaco S, et al. Trial of tocilizumab in giant-cell arteritis. N Engl J Med. 2017 Jul;377(4):317–328. doi: 10.1056/NEJMoa1613849

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.