1,701
Views
73
CrossRef citations to date
0
Altmetric
Original Articles

Preliminary evidence for deficits in multisensory integration in autism spectrum disorders: The mirror neuron hypothesis

&
Pages 348-355 | Received 15 Dec 2006, Published online: 31 Oct 2008

References

  • Abell , F. , Krams , M. , Ashburner , J. , Passingham , R. E. , Friston , K. J. Frackowiak , R. S. J. 1999 . The neuroanatomy of autism: A voxel based whole brain analysis of structural scans . Neuroreport , 10 : 1647 – 1651 .
  • Altschuler , E. L. , Vankov , A. , Hubbard , E. M. , Roberts , E. , Ramachandran , V. S. , & Pineda , J. A. ( 2000 , November ). Mu wave blocking by observer of movement and its possible use as a tool to study theory of other minds . Poster session presented at the 30th Annual Meeting of the Society for Neuroscience, New Orleans, LA .
  • American Psychiatric Association . 2000 . Diagnostic and statistical manual of mental disorders (DSM-IVTR) (4th ed., text revision) . Washington, DC : American Psychiatric Press, Inc .
  • Arbib , M. A. 2005 . From monkey-like action recognition to human language: An evolutionary framework for neurolinguistics . Behavioral and Brain Sciences , 28 (2) , 105 – 124 (discussion 125–167) .
  • Bacon , A. L. , Fein , D. , Morris , R. , Waterhouse , L. and Allen , D. 1998 . The responses of autistic children to the distress of others . Journal of Autism and Developmental Disorders , 2 : 129 – 142 .
  • Baron-Cohen , S. 2001 . Theory of mind and autism: A review . In L. M. Glidden International review of research in mental retardation: Vol. 23. Autism . (pp. 169 – 184 ). San Diego, CA : Academic Press .
  • Bebko , J. M. , Weiss , J. A. , Demark , J. L. and Gomez , P. 2006 . Discrimination of temporal synchrony in intermodal events by children with autism and children with developmental disabilities without autism . Journal of Child Psychology and Psychiatry , 47 : 88 – 98 .
  • Calvert , G. A. and Campbell , R. 2003 . Reading speech from still and moving faces: The neural substrates of visible speech . Journal of Cognitive Neuroscience , 15 ( 1 ) : 50 – 70 .
  • Carr , L. , Iacoboni , M. , Dubeau , M.-C. , Mazziotta , J. C. and Lenzi , G. L. 2003 . Neural mechanisms of empathy in humans: A relay from neural systems for imitation to limbic areas . Proceedings of the National Academy of Sciences USA , 100 : 5497 – 5502 .
  • Collet , L. , Rogé , B. , Descouens , D. , Moron , P. , Duverdy , F. and Urgell , H. 1993 . Objective auditory dysfunction in infantile autism . Lancet , 342 : 923 – 924 .
  • Dapretto , M. , Davies , M. , Pfeifer , J. , Scott , A. , Sigman , M. Bookheimer , S. 2005 . Understanding emotions in others: Mirror neuron dysfunction in children with autism spectrum disorders . Nature Neuroscience , 9 : 28 – 30 .
  • Davis , R. 1961 . The fitness of names to drawings: A cross-cultural study in Tanganyika . British Journal of Psychology , 52 : 259 – 268 .
  • Di Pellegrino , G. , Fadiga , L. , Fogassi , L. , Gallese , V. and Rizzolatti , G. 1992 . Understanding motor events: A neurophysiological study . Experimental Brain Research , 91 : 176 – 180 .
  • Fadiga , L. , Craighero , L. , Buccino , G. and Rizzolatti , G. 2002 . Short communication. Speech listening specifically modulates the excitability of tongue muscles: A TMS study . European Journal of Neuroscience , 15 : 399 – 402 .
  • Fadiga , L. , Fogassi , L. , Pavesi , G. and Rizzolatti , G. 1995 . Motor facilitation during action observation: A magnetic stimulation study . Journal of Neurophysiology , 73 ( 6 ) : 2608 – 2611 .
  • Frith , U. 1989 . Autism and Asperger syndrome , London : MRC Cognitive Development Unit .
  • Gomot , M. , Giard , M. H. , Adrien , J. L. , Barthelemy , C. and Bruneau , N. 2001 . Auditory mismatch process in children with autism: An ERP topographic study . International Journal of Psychophysiology , 41 : 197 – 235 .
  • Hadjikhani , N. , Joseph , R. , Snyder , J. and Tager-Flusberg , H. 2006 . Anatomical differences in the mirror neuron system and social cognition network in autism . Cerebral Cortex , 16 : 1276 – 1282 .
  • Hamilton , A. F. , de , C. , Brindley , R. F. and Frith , U. 2007 . Imitation and action understanding in autistic spectrum disorders: How valid is the hypothesis of a deficit in the mirror neuron system? . Neuropsychologia , 45 : 1859 – 1868 .
  • Hauk , O. , Johnsrude , I. and Pulvermüller , F. 2004 . Somatotopic representation of action words in human motor and premotor cortex . Neuron , 41 : 301 – 307 .
  • Hauk , O. and Pulvermüller , F. 2004 . Neurophysiological distinction of action words in the fronto-central cortex . Human Brain Mapping , 21 : 191 – 201 .
  • Jacob , P. and Jeannerod , M. 2005 . The motor theory of social cognition: A critique . Trends in Cognitive Sciences , 9 : 21 – 25 .
  • Just , M. A. , Cherkassky , V. , Keller , T. A. and Minshew , N. J. 2004 . Cortical activation and synchronization during sentence comprehension in high-functioning autism: Evidence of underconnectivity . Brain , 127 : 1811 – 1821 .
  • Keysers , C. , Kohler , E. , Umiltà , M. A. , Fogassi , L. , Nanetti , L. and Gallese , V. 2003 . Audiovisual mirror neurons and action recognition . Experimental Brain Research , 153 : 628 – 636 .
  • Khalfa , S. , Bruneau , N. , Roge , B. , Georgieff , N. , Veuillet , E. Adrien , J. L. 2001 . Peripheral auditory asymmetry in infantile autism . European Journal of Neuroscience , 13 : 628 – 632 .
  • Kjelgaard , M. M. and Tager-Flusberg , H. 2001 . An investigation of language impairment in autism: Implications for genetic subgroups . Language and Cognitive Processes , 16 : 287 – 308 .
  • Kohler , E. , Keysers , C. , Umiltà , M. A. , Fogassi , L. , Gallese , V. and Rizzolatti , G. 2002 . Hearing sounds, understanding actions: Action representation in mirror neurons . Science , 297 : 846 – 848 .
  • Köhler , W. 1929 . Gestalt psychology , New York : Liveright .
  • Köhler , W. 1947 . Gestalt psychology , 2nd. ed , New York : Liveright .
  • Liberman , A. M. and Mattingly , I. G. 1985 . The motor theory of speech perception revised . Cognition , 21 : 1 – 36 .
  • Lord , C. , Rutter , M. , DiLavore , P. C. , & Risi , S. 1999 . Autism Diagnostic Observation Schedule-WPS (WPS ed.) . Los Angeles : Western Psychological Services .
  • Nishitani , N. , Avikainen , S. and Hari , R. 2004 . Abnormal imitation-related cortical activation sequences in Asperger's syndrome . Annals of Neurology , 55 : 558 – 562 .
  • Oberman , L. M. , Hubbard , E. M. , McCleery , J. P. , Altschuler , E. L. , Ramachandran , V. S. and Pineda , J. A . 2005a . EEG evidence for mirror neuron dysfunction in autism spectrum disorders . Cognitive Brain Research , 24 : 190 – 198 .
  • Oberman , L. M. , Pineda , J. A. , & Ramachandran , V. S. 2005b . EEG evidence for the role of the mirror neuron system in metaphor comprehension . Presented at the 35th Annual Meeting of the Society for Neuroscience, Washington, DC, USA .
  • Plaisted , K. , Saksida , L. , Alcantara , J. and Weisblatt , E. 2003 . Towards an understanding of the mechanisms of weak central coherence effects: Experiments in visual configural learning and auditory perception. Philosophical Transactions of the Royal Society of London . Series B: Biological Sciences , 358 : 375 – 386 .
  • Ramachandran , V. S. ( 2000 , June ). Mirror neurons and imitation learning as the driving force behind the great leap forward in human evolution . Edge , 69 . (Available from: http://www.edge.org/3rd_culture/ramachandran/ramachandran_p1.html )
  • Ramachandran , V. S. , Azoulai , S. , Stone , L. , Srnivasan , A. V. , & Bijoy , N. 2005 . Grasping metaphors and thinking with pictures: How brain damage might affect thought and language . Poster Presented at the 12th Annual Meeting of the Cognitive Neuroscience Society, April 2005, New York, USA .
  • Ramachandran , V. S. and Hubbard , E. M. 2001 . Synaesthesia: A window into perception, thought and language . Journal of Consciousness Studies , 8 : 3 – 34 .
  • Rizzolatti , G. and Arbib , M. A. 1998 . Language within our grasp . Trends in Neuroscience , 21 : 188 – 194 .
  • Rizzolatti , G. , Fogassi , L. and Gallese , V. 2001 . Neurophysiological mechanisms underlying the understanding and imitation of action . Nature Reviews Neuroscience , 2 : 661 – 670 .
  • Rogers , S. J. , Hepburn , S. L. , Stackhouse , T. and Wehner , E. 2003 . Imitation performance in toddlers with autism and those with other developmental disorders . Journal of Child Psychology and Psychiatry , 44 : 763 – 781 .
  • Smith , E. G. , & Bennetto , L. 2007 . Audiovisual speech integration and lipreading in autism . Journal of Child Psychology and Psychiatry , 48 , 813 – 821 .
  • Tager-Flusberg , H. 2000 . “ Understanding the language and communicative impairments in autism ” . In Autism , Edited by: Glidden , L. M. 185 – 205 . San Diego, CA : Academic Press .
  • Theoret , H. , Halligan , E. , Kobayashi , M. , Fregni , F. , Tager-Flusberg , H. and Pascual-Leone , A. 2005 . Impaired motor facilitation during action observation in individuals with autism spectrum disorder . Current Biology , 15 : R84 – 85 .
  • Villalobos , M. E. , Mizuno , A. , Dahl , B. C. , Kemmotsu , N. and Müller , R. A. 2005 . Reduced functional connectivity between V1 and inferior frontal cortex associated with visuomotor performance in autism . NeuroImage , 25 : 916 – 925 .
  • Watkins , K. E. , Strafella , A. P. and Paus , T. 2003 . Seeing and hearing speech excites the motor system involved in speech production . Neuropsychologia , 41 : 989 – 994 .
  • Williams , J. H. G. , Whiten , A. , Suddendorf , T. and Perrett , D. I. 2001 . Imitation, mirror neurons and autism . Neuroscience and Biobehaviour Review , 25 : 287 – 295 .
  • Wilson , S. M. , Saygin , A. P. , Sereno , M. I. and Iacoboni , M. 2004 . Listening to speech activates motor areas involved in speech production . Nature Neuroscience , 7 ( 7 ) : 701 – 702 .
  • Zilbovicius , M. , Boddaert , N. , Belin , B. P. , Poline , J. B. , Remy , P. Mangin , J. F. 2000 . Temporal lobe dysfunction in childhood autism: A PET study . American Journal of Psychiatry , 157 : 1988 – 1993 .
  • Zilbovicius , M. , Garreau , B. , Samson , Y. , Remy , P. , Barthélémy , C. Syrota , A. 1995 . Delayed maturation of the frontal cortex in childhood autism . American Journal of Psychiatry , 152 : 248 – 252 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.