Severe acute pancreatitis: The continued challenge

References

• Andersson R, Wang XD, Ihse I. The influence of abdominal sepsis on acute pancreatitis in rats: a study on mortality, permeability, arterial pressure, and intestinal blood flow. Pancreas 1995; 11: 365–73
   PubMed Web of Science ®Google Scholar
• Wang XD, Wang Q, Andersson R, Ihse I. Alterations in intestinal function in acute pancreatitis in an experimental model. Br J Surg 1996; 83: 1537–43
   PubMed Web of Science ®Google Scholar
• Wang XD, Andersson R, Soltesz V, Leveau P, Ihse I. Gut origin sepsis, macrophage function, and oxygen extraction associated with acute pancreatitis in the rat. World J Surg 1996; 20: 299–308
   PubMed Web of Science ®Google Scholar
• Andersson R, Wang XD, Sun ZW, Deng XM, Soltesz V, Ihse I. Effect of a platelet-activating factor antagonist on pancreatitis-associated gut barrier dysfunction in rats. Pancreas 1998; 17: 107–19
   PubMed Web of Science ®Google Scholar
• Wang XD, Sun ZW, Börjesson A, Andersson R. Inhibition of platelet-activating factor, intercellular adhesion molecule 1 and platelet endothelial cell adhesion molecule 1 reduces experimental pancreatitis-associated gut endothelial barrier dysfunction. Br J Surg 1999; 86: 411–6
   PubMed Web of Science ®Google Scholar
• Wang XD, Börjesson A, Sun ZW, Wallén R, Deng XM, Zhang HY, et al. The association of type II pneumocytes and endothelial permeability with the pulmonary custocyte system in experimental acute pancreatitis. Eur J Clin Invest 1998; 28: 778–85
   PubMedGoogle Scholar
• Wang XD, Sun ZW, Börjesson A, Haraldsen P, Aldman M, Deng XM, et al. Treatment with lexipafant ameliorates the severity of pancreatic microvascular endothelial barrier dysfunction in rats with acute hemorrhagic pancreatitis. Int J Pancreatol 1999; 25: 45–52
   PubMedGoogle Scholar
• Dib M, Zhao X, Wang XD, Andersson R. The role of mast cells in the development of pancreatitis-induced multiple organ dysfunction. Br J Surg 2002; 89: 172–8
   PubMed Web of Science ®Google Scholar
• Dib M, Zhao X, Wang XD, Andersson R. Mast cells contribute to early pancreatitis-induced systemic endothelial barrier dysfunction. Pancreatology 2002; 2: 396–401
   Google Scholar
• Dib M, Zhao X, Wang XD, Andersson E, Drewsen G, Andersson R. Acute phase response in acute pancreatitis: a comparison with abdominal sepsis. Scand J Gastroenterol 2003; 38: 1072–7
   PubMed Web of Science ®Google Scholar
• Shi C, Zhao X, Wang XD, Andersson R. Role of nuclear factor-kappaB, reactive oxygen species and cellular signalling in the early phase of acute pancreatitis. Scand J Gastroenterol 2005; 40: 103–8
   PubMed Web of Science ®Google Scholar
• Haraldsen P, Sun ZW, Börjesson A, Olanders K, Lasson Å, Andersson R. Multimodal management—of value in fulminant acute pancreatitis?. Pancreatology 2003; 3: 14–25
   PubMedGoogle Scholar
• Ederoth P, Sun ZW, Nordström C-H, Andersson R. Experimental pancreatitis causes acute perturbation of energy metabolism in the intestinal wall. Pancreas 2002; 25: 270–6
   PubMedGoogle Scholar
• Qader SS, Ekelund M, Andersson R, Obermuller S, Salehi A. Acute pancreatitis, expression of inducible nitric oxide synthase and defective insulin secretion. Cell Tissue Res 2003; 313: 271–9
   PubMed Web of Science ®Google Scholar
• Leveau P, Wang XD, Sun ZW, Börjesson A, Andersson E, Andersson R. Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant. Biochem Pharmacol 2005; 69: 1325–31
   PubMed Web of Science ®Google Scholar
• Zhao X, Dib M, Andersson R, Andersson E, Widegren B, Rosendahl A, et al. Alterations of adhesion molecule expression and inflammatory mediators in acute lung injury associated by septic and non-septic challenges. Lung 2005; 183: 87–100
   PubMed Web of Science ®Google Scholar
• Buter A, Imrie CW, Carter CR, Evans S, McKay CJ. Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis. Br J Surg 2002; 89: 298–302
   PubMed Web of Science ®Google Scholar
• Andersson E, Andersson R. Exocrine insufficiency in acute pancreatitis [Review]. Scand J Gastroenterol 2004; 39: 1035–9
   PubMed Web of Science ®Google Scholar
• Eckerwall G, Axelsson JB, Andersson R. Early nasogastric feeding in predicted severe acute pancreatitis—a clinical randomized study. Ann Surg 2006; In press.
   Google Scholar
• Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001; 345: 1359–67
   PubMed Web of Science ®Google Scholar