Epidemiology and treatment of relative anemia in children with sickle cell disease in sub-Saharan Africa

References

• Hoffbrand V, Moss PA. Essential haematology. John Wiley & Sons; 2011. Available from: http://www.wileyessential.com/haematology/
   Google Scholar
• Diallo DA, Guindo A. Sickle cell disease in sub-Saharan Africa: stakes and strategies for control of the disease. Curr Opin Hematol. 2014;21(3):210–214.
   PubMed Web of Science ®Google Scholar
• Beaumont C. Disorders of iron homeostasis, erythrocytes, erythropoiesis: the handbook: European school of haematology. Available from: http://www.esh.org/esh-handbook-on-disorders-of-iron-metabolism-2009/
   Google Scholar
• Brown AK, Sleeper LA, Miller ST, et al. Reference values and hematologic changes from birth to 5 years in patients with sickle cell disease. Cooperative study of sickle cell disease. Arch Pediatr Adolesc Med. 1994;148:796–804.
   PubMedGoogle Scholar
• Brown B, Jacob N, Lagunju I, et al. Morbidity and mortality pattern in hospitalized children with sickle cell disorders at the University College Hospital, Ibadan, Nigeria. Niger J Paediatr. 2013;40:34–39.
   Google Scholar
• Gill FM, Sleeper LA, Weiner SJ, et al. Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative study of sickle cell disease. Blood. 1995;86:776–783.
   PubMed Web of Science ®Google Scholar
• Juwah AI, Nlemadim EU, Kaine W. Types of anaemic crises in paediatric patients with sickle cell anaemia seen in Enugu, Nigeria. Arch Dis Child. 2004;89:572–576.
   PubMed Web of Science ®Google Scholar
• Aloni MN, Tshimanga BK, Ekulu PM, et al. Malaria, clinical features and acute crisis in children suffering from sickle cell disease in resource-limited settings: a retrospective description of 90 cases. Pathog Glob Health. 2013;107:198–201.
   PubMed Web of Science ®Google Scholar
• Gardner K, Hoppe C, Mijovic A, et al. How we treat delayed haemolytic transfusion reactions in patients with sickle cell disease. Br J Haematol. 2015;170:745–756.
   PubMed Web of Science ®Google Scholar
• Martyres DJ, Vijenthira A, Barrowman N, et al. Nutrient insufficiencies/Deficiencies in children with sickle cell disease and its association with increased disease severity. Pediatr Blood Cancer. 2016;63(6):1060–1064.
   PubMed Web of Science ®Google Scholar
• Vichinsky E, Kleman K, Embury S, et al. The diagnosis of iron deficiency anemia in sickle cell disease. Blood. 1981;58:963–968.
   PubMed Web of Science ®Google Scholar
• Carmel R, Bellevue R, Kelman Z. Low cobalamin levels associated with sickle cell disease: contrasting origins and clinical meanings in two instructive patients. Am J Hematol. 2010;85:436–439.
   PubMed Web of Science ®Google Scholar
• Kennedy TS, Fung EB, Kawchak DA, et al. Red blood cell folate and serum vitamin B12 status in children with sickle cell disease. J Pediatr Hematol Oncol. 2001;23:165–169.
   PubMed Web of Science ®Google Scholar
• Osungbade KO, Oladunjoye AO. Anaemia in developing countries: Burden and prospects of prevention and control. 2012. Available from: http://www.intechopen.com/books/anemia/anaemia-in-developing-countries-burden-and-prospects-of-prevention-and-control
   Google Scholar
• Tolentino K, Friedman JF. An update on anemia in less developed countries. Am J Trop Med Hyg. 2007;77:44–51.
   PubMed Web of Science ®Google Scholar
• Camaschella C. Iron deficiency: new insights into diagnosis and treatment. Hematology Am Soc Hematol Educ Program. 2015;2015:8–13.
   PubMed Web of Science ®Google Scholar
• Balarajan Y, Ramakrishnan U, Ozaltin E, et al. Anaemia in low-income and middle-income countries. Lancet. 2011;378:2123–2135.
   PubMed Web of Science ®Google Scholar
• Okeahialam TC, Obi GO. Iron deficiency in sickle cell anaemia in Nigerian children. Ann Trop Paediatr. 1982;2:89–92.
   PubMedGoogle Scholar
• Tshilolo L, Zita MN, Ngiyulu R, et al. Iron status in 72 Congolese patients with sickle cell anemia. Medecine et sante tropicales. 2016;26:83–87.
   PubMedGoogle Scholar
• Jeremiah ZA, Buseri FI, Uko EK. Iron deficiency anaemia and evaluation of the utility of iron deficiency indicators among healthy Nigerian children. Hematology. 2007;12:249–253.
   PubMed Web of Science ®Google Scholar
• Dixit R, Nettem S, Madan SS, et al. Folate supplementation in people with sickle cell disease. Cochrane Database Syst Rev. 2016;2:CD011130.
   PubMedGoogle Scholar
• Al-Momen AK. Diminished vitamin B12 levels in patients with severe sickle cell disease. J Intern Med. 1995;237:551–555.
   PubMed Web of Science ®Google Scholar
• Galadanci N, Wudil BJ, Balogun TM, et al. Current sickle cell disease management practices in Nigeria. Int Health. 2014;6:23–28.
   PubMed Web of Science ®Google Scholar
• Carmel R. The laboratory diagnosis of megaloblastic anemias. West J Med. 1978;128:294–304.
   PubMedGoogle Scholar
• Uusiku NP, Oelofse A, Duodu KG, et al. Nutritional value of leafy vegetables of sub-Saharan Africa and their potential contribution to human health: a review. J Food Composition Anal. 2010;23:499–509.
   Web of Science ®Google Scholar
• Kwenin W, Wolli M, Dzomeku B. Assessing the nutritional value of some African indigenous green leafy vegetables in Ghana. J Anim Plant Sci. 2011;10:1300–1305.
   Google Scholar
• Magalhaes RJ, Clements AC. Mapping the risk of anaemia in preschool-age children: the contribution of malnutrition, malaria, and helminth infections in West Africa. PLoS Med. 2011;8:e1000438.
   PubMed Web of Science ®Google Scholar
• Crawley J, Chu C, Mtove G, et al. Malaria in children. Lancet. 2010;375:1468–1481.
   PubMed Web of Science ®Google Scholar
• Makani J, Ofori-Acquah SF, Nnodu O, et al. Sickle cell disease: new opportunities and challenges in Africa. Scientific World J. 2013;2013:193252.
   Web of Science ®Google Scholar
• Bamidele Abiodun I, Oluwadun A, Olugbenga Ayoola A, et al. Plasmodium falciparum merozoite surface protein-1 polymorphisms among asymptomatic sickle cell anemia patients in Nigeria. Acta Medica Iranica. 2016;54:44–53.
   PubMedGoogle Scholar
• Onwubalili JK. Sickle cell disease and infection. J Infect. 1983;7:2–20.
   PubMed Web of Science ®Google Scholar
• Greenwood BM, Bojang K, Whitty CJ, et al. Malaria. Lancet. 2005;365:1487–1498.
   PubMed Web of Science ®Google Scholar
• Crawley J. Reducing the burden of anemia in infants and young children in malaria-endemic countries of Africa: from evidence to action. Am J Trop Med Hyg. 2004;71:25–34.
   PubMed Web of Science ®Google Scholar
• Awolola TS, Oduola AO, Obansa JB, et al. Anopheles gambiae s.s. breeding in polluted water bodies in urban Lagos, southwestern Nigeria. J Vector Borne Dis. 2007;44:241–244.
   PubMedGoogle Scholar
• Oniyangi O, Omari AA. Malaria chemoprophylaxis in sickle cell disease. Cochrane Database Syst Rev. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003489.
   PubMed Web of Science ®Google Scholar
• Olds GR. Deworming the world. Trans Am Clin Climatol Assoc. 2013;124:265–274.
   PubMedGoogle Scholar
• World Health Organization. Soil Transmitted Helminthes. Fact sheet 2016.
   Google Scholar
• Sodipo JO, Padgett D, Warrie E, et al. Parasitic infections in sickle cell crisis: Nigerian experience. J Natl Med Assoc. 1997;89:285–288.
   PubMed Web of Science ®Google Scholar
• Ahmed SG, Uraka J. Impact of intestinal parasites on haematological parameters of sickle-cell anaemia patients in Nigeria. East Mediterr Health J. 2011;17:710–713.
   PubMedGoogle Scholar
• Bethony J, Brooker S, Albonico M, et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 2006;367:1521–1532.
   PubMed Web of Science ®Google Scholar
• Hotez PJ, Brooker S, Bethony JM, et al. Hookworm infection. N Engl J Med. 2004;351:799–807.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Parasites-Hookworm. 2013.
   Google Scholar
• Steketee RW. Pregnancy, nutrition and parasitic diseases. J Nutr. 2003;133:1661S–7S.
   PubMed Web of Science ®Google Scholar
• Stephenson LS, Holland CV, Cooper ES. The public health significance of Trichuris trichiura. Parasitology. 2000;121 Suppl:S73–95.
   PubMed Web of Science ®Google Scholar
• Friedman JF, Kanzaria HK, McGarvey ST. Human schistosomiasis and anemia: the relationship and potential mechanisms. Trends Parasitol. 2005;21:386–392.
   PubMed Web of Science ®Google Scholar
• Prevention Cfdca. Parasites-Schistosomiasis. 2012.
   Google Scholar
• Gurarie D, Wang X, Bustinduy AL, et al. Modeling the effect of chronic schistosomiasis on childhood development and the potential for catch-up growth with different drug treatment strategies promoted for control of endemic schistosomiasis. Am J Trop Med Hyg. 2011;84:773–781.
   PubMed Web of Science ®Google Scholar
• Prual A, Daouda H, Develoux M, et al. Consequences of Schistosoma haematobium infection on the iron status of schoolchildren in Niger. Am J Trop Med Hyg. 1992;47:291–297.
   PubMed Web of Science ®Google Scholar
• Iwalokun BA, Iwalokun SO, Hodonu SO. Seroprevalence of parvovirus B19 antibodies and evidence of viremia among Nigerian patients with sickle cell anemia. J Biomed Res. 2013;27:272–282.
   PubMedGoogle Scholar
• Quek L, Sharpe C, Dutt N, et al. Acute human parvovirus B19 infection and nephrotic syndrome in patients with sickle cell disease. Br J Haematol. 2010;149:289–291.
   PubMed Web of Science ®Google Scholar
• Ubesie A, Emodi I, Ikefuna A, et al. Prevalence of human immunodeficiency virus transmission among transfused children with sickle cell anemia in Enugu Nigeria. Ann Med Health Sci Res. 2012;2:109–113.
   PubMedGoogle Scholar
• Jayaraman S, Chalabi Z, Perel P, et al. The risk of transfusion-transmitted infections in sub-Saharan Africa. Transfusion. 2010;50:433–442.
   PubMed Web of Science ®Google Scholar
• Diarra AB, Guindo A, Kouriba B, et al. Sickle cell anemia and transfusion safety in Bamako, Mali. Seroprevalence of HIV, HBV and HCV infections and alloimmunization belonged to Rh and Kell systems in sickle cell anemia patients. Transfus Clin Biol. 2013;20:476–481.
   PubMed Web of Science ®Google Scholar
• Damen JG, Barnabas O, Damulak D, et al. Malaria parasitemia in apparently healthy blood donors in north-central Nigeria. Lab Med. 2015;46:42–46.
   PubMed Web of Science ®Google Scholar
• Owusu-Ofori AK, Parry C, Bates I. Transfusion-transmitted malaria in countries where malaria is endemic: a review of the literature from sub-Saharan Africa. Clin Infect Dis. 2010;51:1192–1198.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Screening Donated Blood For Transfusion Transmissible Infections. 2010.
   Google Scholar
• World Health Organization. International Program on chemical safety: Lead. 2010.
   Google Scholar
• Wright RO. The role of iron therapy in childhood plumbism. Curr Opin Pediatr. 1999;11:255.
   PubMedGoogle Scholar
• Ajumobi OO, Tsofo A, Yango M, et al. High concentration of blood lead levels among young children in Bagega community, Zamfara - Nigeria and the potential risk factor. Pan Afr Med J. 2014;18(Suppl 1):14.
   PubMedGoogle Scholar
• Dooyema CA, Neri A, Lo YC, et al. Outbreak of fatal childhood lead poisoning related to artisanal gold mining in northwestern Nigeria, 2010. Environ Health Perspect. 2012;120:601–607.
   PubMed Web of Science ®Google Scholar
• Howarth D. Pica – a case report. Aust Fam Physician. 2013;42:299–300.
   PubMed Web of Science ®Google Scholar
• Meier ER, Wright EC, Miller JL. Reticulocytosis and anemia are associated with an increased risk of death and stroke in the newborn cohort of the cooperative study of sickle cell disease. Am J Hematol. 2014;89:904–906.
   PubMed Web of Science ®Google Scholar
• Cancio MI, Helton KJ, Schreiber JE, et al. Silent cerebral infarcts in very young children with sickle cell anaemia are associated with a higher risk of stroke. Br J Haematol. 2015;171:120–129.
   PubMed Web of Science ®Google Scholar
• Lagunju I, Brown BJ, Sodeinde O. Hydroxyurea lowers transcranial Doppler flow velocities in children with sickle cell anaemia in a Nigerian cohort. Pediatr Blood Cancer. 2015;62:1587–1591.
   PubMed Web of Science ®Google Scholar
• Adams RJ. Big strokes in small persons. Arch Neurol. 2007;64:1567–1574.
   PubMed Web of Science ®Google Scholar
• Rees DC, Dick MC, Height SE, et al. A simple index using age, hemoglobin, and aspartate transaminase predicts increased intracerebral blood velocity as measured by transcranial Doppler scanning in children with sickle cell anemia. Pediatrics. 2008;121:e1628–32.
   PubMed Web of Science ®Google Scholar
• Ohene-Frempong K, Weiner SJ, Sleeper LA, et al. Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91:288–294.
   PubMed Web of Science ®Google Scholar
• DeBaun MR, Kirkham FJ. Central nervous system complications and management in sickle cell disease. Blood. 2016;127:829–838.
   PubMed Web of Science ®Google Scholar
• King AA, DeBaun MR, White DA. Need for cognitive rehabilitation for children with sickle cell disease and strokes. Expert Rev Neurother. 2008;8:291–296.
   PubMedGoogle Scholar
• Steen RG, Xiong X, Mulhern RK, et al. Subtle brain abnormalities in children with sickle cell disease: relationship to blood hematocrit. Ann Neurol. 1999;45:279–286.
   PubMed Web of Science ®Google Scholar
• Wang M. Iron deficiency and other types of anemia in infants and children. Am Fam Physician. 2016;93:270–278.
   PubMed Web of Science ®Google Scholar
• Wolf RB, Saville BR, Roberts DO, et al. Factors associated with growth and blood pressure patterns in children with sickle cell anemia: silent cerebral infarct multi-center clinical trial cohort. Am J Hematol. 2015;90:2–7.
   PubMed Web of Science ®Google Scholar
• Hankins JS, Ware RE, Rogers ZR, et al. Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study. Blood. 2005;106:2269–2275.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Nutrition Landscape Information system-Country Profile Indicators, Interpretation guide. 2010.
   Google Scholar
• Esezobor CI, Akintan P, Akinsulie A, et al. Wasting and stunting are still prevalent in children with sickle cell anaemia in Lagos, Nigeria. Ital J Pediatr. 2016;42:45.
   PubMed Web of Science ®Google Scholar
• Cox SE, Makani J, Fulford AJ, et al. Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania. Haematologica. 2011;96:948–953.
   PubMed Web of Science ®Google Scholar
• Wang WC, Ware RE, Miller ST, et al. Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG). Lancet. 2011;377:1663–1672.
   PubMed Web of Science ®Google Scholar
• Hankins JS, Penkert RR, Lavoie P, et al. Parvovirus B19 infection in children with sickle cell disease in the hydroxyurea era. Exp Biol Med (Maywood). 2016;241(7):749–754.
   PubMed Web of Science ®Google Scholar
• Ware RE. Optimizing hydroxyurea therapy for sickle cell anemia. Hematology Am Soc Hematol Educ Program. 2015;2015:436–443.
   PubMedGoogle Scholar
• Ozdemir N. Iron deficiency anemia from diagnosis to treatment in children. Turk Pediatri Ars. 2015;50:11–19.
   PubMedGoogle Scholar
• Makani J, Roberts DJ. Hematology in Africa. Hematol Oncol Clin North Am. 2016;30:457–475.
   PubMed Web of Science ®Google Scholar
• Quinn CT, Rogers ZR, McCavit TL, et al. Improved survival of children and adolescents with sickle cell disease. Blood. 2010;115:3447–3452.
   PubMed Web of Science ®Google Scholar