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Expert Review of Respiratory Medicine Volume 10, 2016 - Issue 10
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Editorial

Can we prevent childhood asthma before birth? Summary of the VDAART results so far

Scott T. WeissChanning Division of Network Medicine, Brigham and Women’s Hospital, Boston, MA, USACorrespondence[email protected]
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Augusto A. LitonjuaChanning Division of Network Medicine, Brigham and Women’s Hospital, Boston, MA, USAView further author information
Pages 1039-1040 | Received 15 Jun 2016, Accepted 18 Aug 2016, Published online: 06 Sep 2016

References

  • Raby BA, Lazarus R, Silverman EK, et al. Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med. 2004 Nov 15;170(10):1057–1065. Epub 2004 Jul 28 PMID: 15282200.
  • Camargo CA, Rifas-Shiman SL, Litonjua AA, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr. 2007 Mar;85(3):788–795. PMID: 17344501.
  • Devereux G, Litonjua AA, Turner SW, et al. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr. 2007 Mar;85(3):853–859. PMID: 17344509.
  • Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol. 2007 Nov;120(5):1031–1035. Epub 2007 Oct 24 PMID: 17919705.
  • Litonjua AA, Lange NE, Carey VJ, et al. The Vitamin D Antenatal Asthma Reduction Trial (VDAART): rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for the primary prevention of asthma and allergies in children. Contemp Clin Trials. 2014 May;38(1):37–50. doi:10.1016/j.cct.2014.02.006. Epub 2014 Mar 12.
  • Litonjua AA, Carey VJ, Laranjo N, et al. Effect of prenatal supplementation with vitamin d on asthma or recurrent wheezing in offspring by age 3 years: the VDAART randomized clinical trial. JAMA. 2016 Jan 26;315(4):362–370. PMID: 26813209. doi:10.1001/jama.2015.18589.
  • Kho AT, Sharma S, Qiu W, et al. Vitamin D related genes in lung development and asthma pathogenesis BMC. Med Genomics. 2013 Nov 5;6:47. PMID: 24188128. doi:10.1186/1755-8794-6-47.
  • Weiss ST. Perspective: evolution of human skin color: how low levels of vitamin D drove natural selection. In: Litonjua AA, editor. Vitamin D and the Lung. New York (NY): Humana Press; 2012. p. 25–37.
  • Heaney RP. The nutrient problem. Nutr Rev. 2012 Mar;70(3):165–169. doi:10.1111/j.1753-4887.2011.00469.x. Epub 2012 Feb 15.

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