Redox signaling and antioxidant therapies in acute respiratory distress syndrome: a systematic review and meta-analysis

References

• Rezoagli E, Fumagalli R, Bellani G. Definition and epidemiology of acute respiratory distress syndrome. Ann Transl Med. 2017;5(14):282.
   PubMed Web of Science ®Google Scholar
• Ranieri VM, Rubenfeld GD, Thompson BT, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA. 2012;307(23):2526–2533.
   PubMed Web of Science ®Google Scholar
• Rubenfeld GD, Caldwell E, Peabody E, et al. Incidence and outcomes of acute lung injury. N Engl J Med. 2005;353(16):1685–1693.
   PubMed Web of Science ®Google Scholar
• Brun-Buisson C, Minelli C, Bertolini G, et al. Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study. Intensive Care Med. 2004;30(1):51–61.
   PubMed Web of Science ®Google Scholar
• Sakr Y, Vincent JL, Reinhart K, et al. High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest. 2005;128(5):3098–3108.
   PubMed Web of Science ®Google Scholar
• Bellani G, Laffey JG, Pham T, et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. 2016;315(8):788–800.
   PubMed Web of Science ®Google Scholar
• Fan E, Del SL, Goligher EC, et al. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation in adult patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 2017;195(9):1253–1263.
   PubMed Web of Science ®Google Scholar
• Wang C, Wang X, Chi C, et al. Lung ventilation strategies for acute respiratory distress syndrome: a systematic review and network meta-analysis. Sci Rep. 2016;6:22855.
   PubMed Web of Science ®Google Scholar
• Fan E, Brodie D, Slutsky AS. Acute respiratory distress syndrome: advances in diagnosis and treatment. JAMA. 2018;319(7):698–710.
   PubMed Web of Science ®Google Scholar
• Adhikari N, Burns KE, Meade MO. Pharmacologic therapies for adults with acute lung injury and acute respiratory distress syndrome. Cochrane Database Syst Rev. 2004;(4):D4477. DOI:https://doi.org/10.1002/14651858.CD004477.pub2
   Google Scholar
• Matthay MA, Zemans RL, Zimmerman GA, et al. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019;5(1):18.
   PubMed Web of Science ®Google Scholar
• Guerin C, Reignier J, Richard JC, et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med. 2013;368(23):2159–2168.
   PubMed Web of Science ®Google Scholar
• Papazian L, Forel JM, Gacouin A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107–1116.
   PubMed Web of Science ®Google Scholar
• Erol N, Saglam L, Saglam YS, et al. The protection potential of antioxidant vitamins against acute respiratory distress syndrome: a rat trial. Inflammation. 2019;42(5):1585–1594.
   PubMed Web of Science ®Google Scholar
• Chen L, Li W, Qi D, et al. Lycium barbarum polysaccharide protects against LPS-induced ARDS by inhibiting apoptosis, oxidative stress, and inflammation in pulmonary endothelial cells. Free Radic Res. 2018;52(4):480–490.
   PubMed Web of Science ®Google Scholar
• Kellner M, Noonepalle S, Lu Q, et al. ROS signaling in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Adv Exp Med Biol. 2017;967:105–137.
   PubMed Web of Science ®Google Scholar
• Fowler AR, Truwit JD, Hite RD, et al. Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure: the CITRIS-ALI randomized clinical trial. JAMA. 2019;322(13):1261–1270.
   PubMed Web of Science ®Google Scholar
• Bernard GR, Wheeler AP, Arons MM, et al. A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The antioxidant in ARDS study group. Chest. 1997;112(1):164.
   PubMed Web of Science ®Google Scholar
• Suter PM, Domenighetti G, Schaller MD, et al. N-acetylcysteine enhances recovery from acute lung injury in man. A randomized, double-blind, placebo-controlled clinical study. Chest. 1994;105(1):190–194.
   PubMed Web of Science ®Google Scholar
• Domenighetti G, Suter PM, Schaller MD, et al. Treatment with N-acetylcysteine during acute respiratory distress syndrome: a randomized, double-blind, placebo-controlled clinical study. J Crit Care. 1997;12(4):177–182.
   PubMed Web of Science ®Google Scholar
• Jepsen S, Herlevsen P, Knudsen P, et al. Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: a prospective, randomized, placebo-controlled study. Crit Care Med. 1992;20(7):918–923.
   PubMed Web of Science ®Google Scholar
• Moradi M, Mojtahedzadeh M, Mandegari A, et al. The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine. Respir Med. 2009;103(3):434–441.
   PubMed Web of Science ®Google Scholar
• Ortolani O, Conti A, De Gaudio AR, et al. Protective effects of N-acetylcysteine and rutin on the lipid peroxidation of the lung epithelium during the adult respiratory distress syndrome. Shock. 2000;13(1):14–18.
   PubMed Web of Science ®Google Scholar
• Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Open Med. 2009;3(3):e123–e130.
   PubMedGoogle Scholar
• Higgins JP, Altman DG, Gotzsche PC, et al. The Cochrane collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
   PubMed Web of Science ®Google Scholar
• Li C, Bo L, Liu W, et al. Enteral immunomodulatory diet (omega-3 fatty acid, gamma-linolenic acid and antioxidant supplementation) for acute lung injury and acute respiratory distress syndrome: an updated systematic review and meta-analysis. Nutrients. 2015;7(7):5572–5585.
   PubMed Web of Science ®Google Scholar
• Mahmoodpoor A, Hamishehkar H, Shadvar K, et al. The effect of intravenous selenium on oxidative stress in critically ill patients with acute respiratory distress syndrome. Immunol Invest. 2019;48(2):147–159.
   PubMed Web of Science ®Google Scholar
• Shirai K, Yoshida S, Matsumaru N, et al. Effect of enteral diet enriched with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with sepsis-induced acute respiratory distress syndrome. J Intensive Care. 2015;3(1):24.
   Google Scholar
• Elamin EM, Miller AC, Ziad S. Immune enteral nutrition can improve outcomes in medical-surgical patients with ARDS: a prospective randomized controlled trial. J Nutr Disord Ther. 2012;2:109.
   PubMedGoogle Scholar
• Grau-Carmona T, Morán-García V, García-de-lorenzo A, et al. Effect of an enteral diet enriched with eicosapentaenoic acid, gamma-linolenic acid and anti-oxidants on the outcome of mechanically ventilated, critically ill, septic patients. Clin Nutr. 2011;30(5):578–584.
   PubMed Web of Science ®Google Scholar
• Rice TW, Wheeler AP, Thompson BT, et al. Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA. 2011;306(14):1574–1581.
   PubMed Web of Science ®Google Scholar
• Morris PE, Papadakos P, Russell JA, et al. A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome. Crit Care Med. 2008;36(3):782–788.
   PubMed Web of Science ®Google Scholar
• Singer P, Theilla M, Fisher H, et al. Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. Crit Care Med. 2006;34(4):1033–1038.
   PubMed Web of Science ®Google Scholar
• Martin GS, Moss M, Wheeler AP, et al. A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury. Crit Care Med. 2005;33(8):1681–1687.
   PubMed Web of Science ®Google Scholar
• Martin GS. Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury. JAMA. 2003;289(9):1083.
   Google Scholar
• Network A. Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. Crit Care Med. 2002;30(1):1–6.
   PubMed Web of Science ®Google Scholar
• Gadek JE, DeMichele SJ, Karlstad MD, et al. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral nutrition in ARDS study group. Crit Care Med. 1999;27(8):1409–1420.
   PubMed Web of Science ®Google Scholar
• Metnitz PG, Bartens C, Fischer M, et al. Antioxidant status in patients with acute respiratory distress syndrome. Intensive Care Med. 1999;25(2):180–185.
   PubMed Web of Science ®Google Scholar
• Ward C, Schlingmann B, Stecenko AA, et al. NF-kappaB inhibitors impair lung epithelial tight junctions in the absence of inflammation. Tissue Barriers. 2015;3(1–2):e982424.
   PubMed Web of Science ®Google Scholar
• Putzu A, Daems AM, Lopez-Delgado JC, et al. The effect of vitamin c on clinical outcome in critically ill patients: a systematic review with meta-analysis of randomized controlled trials. Crit Care Med. 2019;47(6):774–783.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Yang M, Mao Z, et al. The clinical outcomes of selenium supplementation on critically ill patients: a meta-analysis of randomized controlled trials. Medicine (Baltimore). 2019;98(20):e15473.
   PubMed Web of Science ®Google Scholar
• Reilly JP, Calfee CS, Christie JD. Acute respiratory distress syndrome phenotypes. Semin Respir Crit Care Med. 2019;40(1):19–30.
   PubMed Web of Science ®Google Scholar
• Calfee CS, Delucchi K, Parsons PE, et al. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med. 2014;2(8):611–620.
   PubMed Web of Science ®Google Scholar
• Yadav H, Thompson BT, Gajic O. Fifty years of research in ARDS. Is acute respiratory distress syndrome a preventable disease? Am J Respir Crit Care Med. 2017;195(6):725–736.
   PubMed Web of Science ®Google Scholar
• Nathens AB, Neff MJ, Jurkovich GJ, et al. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg. 2002;236(6):814–822.
   PubMed Web of Science ®Google Scholar
• See KC, Sahagun J, Taculod J. Identification of focal ARDS using PF ratio: a cross-sectional study. Crit Care. 2020;24(1):471.
   PubMed Web of Science ®Google Scholar