The individual and societal prices of non-adherence to continuous positive airway pressure, contributors, and strategies for improvement

References

• Benjafield AV, Ayas NT, Eastwood PR, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med. 2019 Aug;7(8):687–698.
   PubMed Web of Science ®Google Scholar
• Levy P, Kohler M, McNicholas WT, et al. Obstructive sleep apnoea syndrome. Nat Rev Dis Primers. 2015 Jun 25;1:15015. DOI:10.1038/nrdp.2015.15
   PubMed Web of Science ®Google Scholar
• Javaheri S, Barbe F, Campos-Rodriguez F, et al. Sleep apnea: types, mechanisms, and clinical cardiovascular consequences. J Am Coll Cardiol. 2017 Feb 21;69(7):841–858. DOI:10.1016/j.jacc.2016.11.069
   PubMed Web of Science ®Google Scholar
• Marin JM, Carrizo SJ, Vicente E, et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet. 2005 Mar 19-25;365(9464):1046–1053. DOI:10.1016/S0140-6736(05)71141-7
   PubMed Web of Science ®Google Scholar
• Yu J, Zhou Z, McEvoy RD, et al. Association of positive airway pressure with cardiovascular events and death in adults with sleep apnea: a systematic review and meta-analysis. JAMA. 2017 Jul 11;318(2):156–166. DOI:10.1001/jama.2017.7967
   PubMed Web of Science ®Google Scholar
• Li Z, Cai S, Wang J, et al. Predictors of the efficacy for daytime sleepiness in patients with obstructive sleep apnea with continual positive airway pressure therapy: a meta-analysis of randomized controlled trials. Front Neurol. 2022;13:911996.
   PubMed Web of Science ®Google Scholar
• Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine Clinical Practice guideline. J Clin Sleep Med. 2019 Feb 15;15(2):335–343. DOI:10.5664/jcsm.7640
   PubMed Web of Science ®Google Scholar
• Bratton DJ, Stradling JR, Barbe F, et al. Effect of CPAP on blood pressure in patients with minimally symptomatic obstructive sleep apnoea: a meta-analysis using individual patient data from four randomised controlled trials. Thorax. 2014 Dec;69(12):1128–1135.
   PubMed Web of Science ®Google Scholar
• Craig S, Pepin JL, Randerath W, et al. Investigation and management of residual sleepiness in CPAP-treated patients with obstructive sleep apnoea: the European view. Eur Respir Rev. 2022 Jun 30;31(164):210230. DOI:10.1183/16000617.0230-2021
   PubMed Web of Science ®Google Scholar
• Gasa M, Tamisier R, Launois SH, et al. Residual sleepiness in sleep apnea patients treated by continuous positive airway pressure. J Sleep Res. 2013 Aug;22(4):389–397.
   PubMed Web of Science ®Google Scholar
• Rosenberg R, Schweitzer PK, Steier J, et al. Residual excessive daytime sleepiness in patients treated for obstructive sleep apnea: guidance for assessment, diagnosis, and management. Postgrad Med. 2021 Sep;133(7):772–783.
   PubMed Web of Science ®Google Scholar
• Weaver TE, Pepin JL, Schwab R, et al. Long-term effects of solriamfetol on quality of life and work productivity in participants with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea. J Clin Sleep Med. 2021 Oct 1;17(10):1995–2007. DOI:10.5664/jcsm.9384
   PubMed Web of Science ®Google Scholar
• Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment. J Clin Sleep Med. 2019 Feb 15;15(2):301–334. DOI:10.5664/jcsm.7638
   PubMed Web of Science ®Google Scholar
• Cistulli PA, Armitstead J, Pepin JL, et al. Short-term CPAP adherence in obstructive sleep apnea: a big data analysis using real world data. Sleep Med. 2019 Jul;59:114–116. DOI:10.1016/j.sleep.2019.01.004
   PubMed Web of Science ®Google Scholar
• Patel SR, Bakker JP, Stitt CJ, et al. Age and Sex Disparities in Adherence to CPAP. Chest. 2021 Jan;159(1):382–389. DOI:10.1016/j.chest.2020.07.017
   PubMed Web of Science ®Google Scholar
• Pandey A, Mereddy S, Combs D, et al. Socioeconomic inequities in adherence to positive airway pressure therapy in population-level analysis. J Clin Med. 2020 Feb 6;9(2):442. DOI:10.3390/jcm9020442
   PubMed Web of Science ®Google Scholar
• McEvoy RD, Antic NA, Heeley E, et al. CPAP for prevention of cardiovascular events in obstructive sleep apnea. N Engl J Med. 2016 Sep 8;375(10):919–931. DOI:10.1056/NEJMoa1606599
   PubMed Web of Science ®Google Scholar
• Sanchez-de-la-Torre M, Sanchez-de-la-Torre A, Bertran S, et al. Effect of obstructive sleep apnoea and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial. Lancet Respir Med. 2020 Apr;8(4):359–367.
   PubMed Web of Science ®Google Scholar
• Gerves-Pinquie C, Bailly S, Goupil F, et al. Positive airway pressure adherence, mortality, and cardiovascular events in patients with sleep apnea. Am J Respir Crit Care Med. 2022 Dec 1;206(11):1393–1404. DOI:10.1164/rccm.202202-0366OC
   PubMed Web of Science ®Google Scholar
• Pepin JL, Bailly S, Rinder P, et al. CPAP therapy termination rates by OSA Phenotype: a French nationwide database analysis. J Clin Med. 2021 Mar 1;10(5):936. DOI:10.3390/jcm10050936
   PubMed Web of Science ®Google Scholar
• Yeghiazarians Y, Jneid H, Tietjens JR, et al. Obstructive sleep apnea and cardiovascular disease: a scientific statement from the American heart association. Circulation. 2021 Jul 20;144(3):e56–67. DOI:10.1161/CIR.0000000000000988
   PubMed Web of Science ®Google Scholar
• Cowie MR, Linz D, Redline S, et al. Sleep disordered breathing and cardiovascular disease: jACC state-of-the-art review. J Am Coll Cardiol. 2021 Aug 10;78(6):608–624. DOI:10.1016/j.jacc.2021.05.048
   PubMed Web of Science ®Google Scholar
• Bratton DJ, Gaisl T, Wons AM, et al. CPAP vs mandibular advancement devices and blood pressure in patients with obstructive sleep apnea: a systematic review and meta-analysis. JAMA. 2015 Dec 1;314(21):2280–2293. DOI:10.1001/jama.2015.16303
   PubMed Web of Science ®Google Scholar
• Weaver TE, Maislin G, Dinges DF, et al. Relationship between hours of CPAP use and achieving normal levels of sleepiness and daily functioning. Sleep. 2007 Jun;30(6):711–719. DOI:10.1093/sleep/30.6.711
   PubMed Web of Science ®Google Scholar
• Malhotra A, Sterling KL, Cistulli PA, et al. Dose-response relationship between obstructive sleep apnea therapy adherence and healthcare utilization. Ann Am Thorac Soc. 2023 Feb 3. DOI:10.1513/AnnalsATS.202208-738OC
   Google Scholar
• May AM, Patel SR, Yamauchi M, et al. Moving toward equitable care for sleep apnea in the United States: positive airway pressure adherence thresholds: an official American Thoracic Society policy statement. Am J Respir Crit Care Med. 2023 Feb 1;207(3):244–254. DOI:10.1164/rccm.202210-1846ST
   PubMedGoogle Scholar
• Platt AB, Field SH, Asch DA, et al. Neighborhood of residence is associated with daily adherence to CPAP therapy. Sleep. 2009 Jun;32(6):799–806.
   PubMed Web of Science ®Google Scholar
• Peker Y, Glantz H, Eulenburg C, et al. Effect of positive airway pressure on cardiovascular outcomes in coronary artery disease patients with nonsleepy obstructive sleep apnea. The RICCADSA randomized controlled trial. Am J Respir Crit Care Med. 2016 Sep 1;194(5):613–620. DOI:10.1164/rccm.201601-0088OC
   PubMed Web of Science ®Google Scholar
• Pepin JL, Bailly S, Rinder P, et al. Relationship between CPAP termination and all-cause mortality: a French nationwide database analysis. Chest. 2022 Jun;161(6):1657–1665.
   PubMed Web of Science ®Google Scholar
• Faria A, Allen AH, Fox N, et al. The public health burden of obstructive sleep apnea. Sleep Sci. 2021 Jul;14(3):257–265.
   PubMed Web of Science ®Google Scholar
• Bock JM, Needham KA, Gregory DA, et al. Continuous positive airway pressure adherence and treatment cost in patients with obstructive sleep apnea and cardiovascular disease. Mayo Clin Proc Innov Qual Outcomes. 2022 Apr;6(2):166–175.
   PubMedGoogle Scholar
• Wickwire EM, Bailey MD, Somers VK, et al. CPAP adherence is associated with reduced risk for stroke among older adult Medicare beneficiaries with obstructive sleep apnea. J Clin Sleep Med. 2021 Jun 1;17(6):1249–1255. DOI:10.5664/jcsm.9176
   PubMed Web of Science ®Google Scholar
• Sterling KL, Pepin JL, Linde-Zwirble W, et al. Impact of positive airway pressure therapy adherence on outcomes in patients with obstructive sleep apnea and chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2022 Jul 15;206(2):197–205. DOI:10.1164/rccm.202109-2035OC
   PubMed Web of Science ®Google Scholar
• Genzor S, Prasko J, Mizera J, et al. Risk of severe COVID-19 in non-adherent OSA patients. Patient Prefer Adherence. 2022;16:3069–3079.
   PubMed Web of Science ®Google Scholar
• Bottaz-Bosson G, Midelet A, Mendelson M, et al. Remote monitoring of positive airway pressure data: challenges, pitfalls and strategies to consider for optimal data science applications. Chest. 2022 [2022 Dec 1];0(0). Doi:10.1016/j.chest.2022.11.034
   Google Scholar
• Midelet A, Borel JC, Tamisier R, et al. Apnea-hypopnea index supplied by CPAP devices: time for standardization? Sleep Med. 2021 May;81:120–122.
   PubMed Web of Science ®Google Scholar
• Pepin JL, Bailly S, Borel JC, et al. Detecting COVID-19 and other respiratory infections in obstructive sleep apnoea patients through CPAP device telemonitoring. Digit Health. 2021 Jan;7:20552076211002957.
   Web of Science ®Google Scholar
• Prigent A, Pellen C, Texereau J, et al. CPAP telemonitoring can track Cheyne-Stokes respiration and detect serious cardiac events: the AlertApnee study. Respirology. 2022 Feb;27(2):161–169.
   PubMed Web of Science ®Google Scholar
• Babbin SF, Velicer WF, Aloia MS, et al. Identifying longitudinal patterns for individuals and subgroups: an example with adherence to treatment for obstructive sleep apnea. Multivariate Behav Res. 2015;50(1):91–108. DOI:10.1080/00273171.2014.958211
   PubMed Web of Science ®Google Scholar
• Bottaz-Bosson G, Hamon A, Pepin JL, et al. Continuous positive airway pressure adherence trajectories in sleep apnea: clustering with summed discrete Frechet and dynamic time warping dissimilarities. Stat Med. 2021 Oct 30;40(24):5373–5396. DOI:10.1002/sim.9130
   PubMed Web of Science ®Google Scholar
• Bettega F, Leyrat C, Tamisier R, et al. Application of inverse-probability-of-treatment weighting to estimate the effect of daytime sleepiness in patients with obstructive sleep apnea. Ann Am Thorac Soc. 2022 Sep;19(9):1570–1580.
   PubMed Web of Science ®Google Scholar
• Midelet A, Bailly S, Tamisier R, et al. Hidden Markov model segmentation to demarcate trajectories of residual apnoea-hypopnoea index in CPAP-treated sleep apnoea patients to personalize follow-up and prevent treatment failure. Epma J. 2021 Dec;12(4):535–544. DOI:10.1007/s13167-021-00264-z
   PubMed Web of Science ®Google Scholar
• Midelet A, Bailly S, Borel JC, et al. Bayesian structural time series with synthetic controls for evaluating the impact of mask changes in residual apnea-hypopnea index telemonitoring data. IEEE J Biomed Health Inform. 2022 Oct;26(10):5213–5222.
   PubMed Web of Science ®Google Scholar
• Sweetman A, Lack L, Bastien C. Co-morbid Insomnia and Sleep Apnea (COMISA): prevalence, consequences, methodological considerations, and recent randomized controlled trials. Brain Sci. 2019 Dec 12;9(12):371.
   PubMed Web of Science ®Google Scholar
• Jacobsen AR, Eriksen F, Hansen RW, et al. Determinants for adherence to continuous positive airway pressure therapy in obstructive sleep apnea. PLoS ONE. 2017;12(12):e0189614. DOI:10.1371/journal.pone.0189614
   PubMed Web of Science ®Google Scholar
• Kohler M, Smith D, Tippett V, et al. Predictors of long-term compliance with continuous positive airway pressure. Thorax. 2010 Sep;65(9):829–832.
   PubMed Web of Science ®Google Scholar
• Campos-Rodriguez F, Martinez-Alonso M, Sanchez-de-la-Torre M, et al. Long-term adherence to continuous positive airway pressure therapy in non-sleepy sleep apnea patients. Sleep Med. 2016 Jan;17:1–6.
   PubMed Web of Science ®Google Scholar
• Rotenberg BW, Murariu D, Pang KP. Trends in CPAP adherence over twenty years of data collection: a flattened curve. J Otolaryngol Head Neck Surg. 2016 Aug 19;45(1):43.
   PubMedGoogle Scholar
• Budhiraja R, Parthasarathy S, Drake CL, et al. Early CPAP use identifies subsequent adherence to CPAP therapy. Sleep. 2007 Mar;30(3):320–324.
   PubMed Web of Science ®Google Scholar
• Gay P, Weaver T, Loube D, et al. Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Sleep. 2006 Mar;29(3):381–401.
   PubMed Web of Science ®Google Scholar
• Hui DS, Chan JK, Choy DK, et al. Effects of augmented continuous positive airway pressure education and support on compliance and outcome in a Chinese population. Chest. 2000 May;117(5):1410–1416.
   PubMed Web of Science ®Google Scholar
• Olsen S, Smith S, Oei T, et al. Health belief model predicts adherence to CPAP before experience with CPAP. Eur Respir J. 2008 Sep;32(3):710–717.
   PubMed Web of Science ®Google Scholar
• Popescu G, Latham M, Allgar V, et al. Continuous positive airway pressure for sleep apnoea/hypopnoea syndrome: usefulness of a 2 week trial to identify factors associated with long term use. Thorax. 2001 Sep;56(9):727–733.
   PubMed Web of Science ®Google Scholar
• Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc. 2008 Feb 15;5(2):173–178.
   PubMedGoogle Scholar
• Brostrom A, Arestedt KF, Nilsen P, et al. The side-effects to CPAP treatment inventory: the development and initial validation of a new tool for the measurement of side-effects to CPAP treatment. J Sleep Res. 2010 Dec;19(4):603–611.
   PubMed Web of Science ®Google Scholar
• Brostrom A, Stromberg A, Ulander M, et al. Perceived informational needs, side-effects and their consequences on adherence - a comparison between CPAP treated patients with OSAS and healthcare personnel. Patient Educ Couns. 2009 Feb;74(2):228–235.
   PubMed Web of Science ®Google Scholar
• Sawyer AM, Canamucio A, Moriarty H, et al. Do cognitive perceptions influence CPAP use? Patient Educ Couns. 2011 Oct;85(1):85–91.
   PubMed Web of Science ®Google Scholar
• Zozula R, Rosen R. Compliance with continuous positive airway pressure therapy: assessing and improving treatment outcomes. Curr Opin Pulm Med. 2001 Nov;7(6):391–398.
   PubMedGoogle Scholar
• Brin YS, Reuveni H, Greenberg S, et al. Determinants affecting initiation of continuous positive airway pressure treatment. Isr Med Assoc J. 2005 Jan;7(1):13–18.
   PubMed Web of Science ®Google Scholar
• Simon-Tuval T, Reuveni H, Greenberg-Dotan S, et al. Low socioeconomic status is a risk factor for CPAP acceptance among adult OSAS patients requiring treatment. Sleep. 2009 Apr;32(4):545–552.
   PubMed Web of Science ®Google Scholar
• Bakker JP, O’Keeffe KM, Neill AM, et al. Ethnic disparities in CPAP adherence in New Zealand: effects of socioeconomic status, health literacy and self-efficacy. Sleep. 2011 Nov 1;34(11):1595–1603. DOI:10.5665/sleep.1404
   PubMed Web of Science ®Google Scholar
• Lewis KE, Seale L, Bartle IE, et al. Early predictors of CPAP use for the treatment of obstructive sleep apnea. Sleep. 2004 Feb 1;27(1):134–138. DOI:10.1093/sleep/27.1.134
   PubMed Web of Science ®Google Scholar
• Billings ME, Auckley D, Benca R, et al. Race and residential socioeconomics as predictors of CPAP adherence. Sleep. 2011 Dec 1;34(12):1653–1658. DOI:10.5665/sleep.1428
   PubMed Web of Science ®Google Scholar
• Campbell A, Neill A, Lory R. Ethnicity and socioeconomic status predict initial continuous positive airway pressure compliance in New Zealand adults with obstructive sleep apnoea. Intern Med J. 2012 Jun;42(6):e95–101.
   PubMed Web of Science ®Google Scholar
• Gulati A, Ali M, Davies M, et al. A prospective observational study to evaluate the effect of social and personality factors on continuous positive airway pressure (CPAP) compliance in obstructive sleep apnoea syndrome. BMC Pulm Med. 2017 Mar 22;17(1):56. DOI:10.1186/s12890-017-0393-7
   PubMedGoogle Scholar
• Ye L, Pack AI, Maislin G, et al. Predictors of continuous positive airway pressure use during the first week of treatment. J Sleep Res. 2012 Aug;21(4):419–426.
   PubMed Web of Science ®Google Scholar
• Becker MH, Maiman LA. Sociobehavioral determinants of compliance with health and medical care recommendations. Med care. 1975 Jan;13(1):10–24.
   PubMed Web of Science ®Google Scholar
• Andrulis DP. Access to care is the centerpiece in the elimination of socioeconomic disparities in health. Ann Intern Med. 1998 Sep 1;129(5):412–416.
   PubMed Web of Science ®Google Scholar
• Potosky AL, Breen N, Graubard BI, et al. The association between health care coverage and the use of cancer screening tests. Results from the 1992 national health interview survey. Med Care. 1998 Mar;36(3):257–270.
   PubMed Web of Science ®Google Scholar
• Schillinger D, Grumbach K, Piette J, et al. Association of health literacy with diabetes outcomes. JAMA. 2002 Jul 24-31;288(4):475–482. DOI:10.1001/jama.288.4.475
   PubMed Web of Science ®Google Scholar
• Williams LK, Joseph CL, Peterson EL, et al. Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids. J Allergy Clin Immunol. 2007 Jan;119(1):168–175.
   PubMed Web of Science ®Google Scholar
• Palm A, Grote L, Theorell-Haglow J, et al. Socioeconomic factors and adherence to CPAP: the population-based course of disease in patients reported to the Swedish CPAP oxygen and ventilator registry study. Chest. 2021 Oct;160(4):1481–1491.
   PubMed Web of Science ®Google Scholar
• Liu D, Armitstead J, Benjafield A, et al. Trajectories of emergent central sleep apnea during CPAP therapy. Chest. 2017 Oct;152(4):751–760.
   PubMed Web of Science ®Google Scholar
• Bailly S, Daabek N, Jullian-Desayes I, et al. Partial failure of CPAP treatment for sleep apnoea: analysis of the French national sleep database. Respirology. 2020 Jan;25(1):104–111.
   PubMed Web of Science ®Google Scholar
• Pepin JL, Woehrle H, Liu D, et al. Adherence to positive airway therapy after switching from CPAP to ASV: a big data analysis. J Clin Sleep Med. 2018 Jan 15;14(1):57–63. DOI:10.5664/jcsm.6880
   PubMed Web of Science ®Google Scholar
• Benjafield AV, Oldstone LM, Willes LA, et al. Positive airway pressure therapy adherence with mask resupply: a propensity-matched analysis. J Clin Med. 2021 Feb 12;10(4):720. DOI:10.3390/jcm10040720
   PubMed Web of Science ®Google Scholar
• Andrade RGS, Viana FM, Nascimento JA, et al. Nasal vs oronasal CPAP for OSA treatment: a meta-analysis. Chest. 2018 Mar;153(3):665–674.
   PubMed Web of Science ®Google Scholar
• Rowland S, Aiyappan V, Hennessy C, et al. Comparing the efficacy, mask leak, patient adherence, and patient preference of three different CPAP interfaces to treat moderate-severe obstructive sleep apnea. J Clin Sleep Med. 2018 Jan 15;14(1):101–108. DOI:10.5664/jcsm.6892
   PubMed Web of Science ®Google Scholar
• Ebben MR, Narizhnaya M, Segal AZ, et al. A randomised controlled trial on the effect of mask choice on residual respiratory events with continuous positive airway pressure treatment. Sleep Med. 2014 Jun;15(6):619–624.
   PubMed Web of Science ®Google Scholar
• Manis E, Cheng H, Shelgikar AV. Elevated residual apnea-hypopnea index on continuous positive airway pressure download after transition to full-face mask. Ann Am Thorac Soc. 2021 Mar;18(3):524–526.
   PubMed Web of Science ®Google Scholar
• Smith I, Lasserson TJ. Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev. 2019 Dec 2;12: CD003531. DOI:10.1002/14651858
   Google Scholar
• Xu T, Li T, Wei D, et al. Effect of automatic versus fixed continuous positive airway pressure for the treatment of obstructive sleep apnea: an up-to-date meta-analysis. Sleep Breath. 2012 Dec;16(4):1017–1026.
   PubMed Web of Science ®Google Scholar
• Gentina T, Bailly S, Jounieaux F, et al. Marital quality, partner’s engagement and continuous positive airway pressure adherence in obstructive sleep apnea. Sleep Med. 2019 Mar;55:56–61.
   PubMed Web of Science ®Google Scholar
• Pepin JL, Daabek N, Bailly S, et al. Adherence to continuous positive airway pressure hugely improved during COVID-19 lockdown in France. Am J Respir Crit Care Med. 2021 Nov 1;204(9):1103–1106. DOI:10.1164/rccm.202103-0803LE
   PubMed Web of Science ®Google Scholar
• Strausz S, Kiiskinen T, Broberg M, et al. Sleep apnoea is a risk factor for severe COVID-19. BMJ Open Respir Res. 2021 Jan;8(1):e000845.
   PubMed Web of Science ®Google Scholar
• Pepin JL, Sauvaget O, Borel JC, et al. Continuous positive airway pressure-treated patients’ behaviours during the COVID-19 crisis. ERJ Open Res. 2020 Oct;6(4):00508–2020.
   PubMedGoogle Scholar
• Demirovic S, Lusic Kalcina L, Pavlinac Dodig I, et al. The COVID-19 lockdown and CPAP adherence: the more vulnerable ones less likely to improve adherence? Nat Sci Sleep. 2021;13:1097–1108.
   PubMed Web of Science ®Google Scholar
• Bertelli F, Suehs CM, Mallet JP, et al. Did COVID-19 impact positive airway pressure adherence in 2020? A cross-sectional study of 8477 patients with sleep apnea. Respir Res. 2022 Mar 4;23(1):46. DOI:10.1186/s12931-022-01969-z
   PubMed Web of Science ®Google Scholar
• Brostrom A, Nilsen P, Johansson P, et al. Putative facilitators and barriers for adherence to CPAP treatment in patients with obstructive sleep apnea syndrome: a qualitative content analysis. Sleep Med. 2010 Feb;11(2):126–130.
   PubMed Web of Science ®Google Scholar
• Merle R, Pison C, Logerot S, et al. Peer-driven intervention to help patients resume CPAP therapy following discontinuation: a multicentre, randomised clinical trial with patient involvement. BMJ Open. 2021 Oct 14;11(10):e053996. DOI:10.1136/bmjopen-2021-053996
   PubMed Web of Science ®Google Scholar
• Troxel WM, Robles TF, Hall M, et al. Marital quality and the marital bed: examining the covariation between relationship quality and sleep. Sleep Med Rev. 2007 Oct;11(5):389–404.
   PubMed Web of Science ®Google Scholar
• Beninati W, Harris CD, Herold DL, et al. The effect of snoring and obstructive sleep apnea on the sleep quality of bed partners. Mayo Clin Proc. 1999 Oct;74(10):955–958.
   PubMed Web of Science ®Google Scholar
• Martire LM, Schulz R, Helgeson VS, et al. Review and meta-analysis of couple-oriented interventions for chronic illness. Ann Behav Med. 2010 Dec;40(3):325–342.
   PubMed Web of Science ®Google Scholar
• Baron KG, Smith TW, Czajkowski LA, et al. Relationship quality and CPAP adherence in patients with obstructive sleep apnea. Behav Sleep Med. 2009;7(1):22–36. DOI:10.1080/15402000802577751
   PubMed Web of Science ®Google Scholar
• Luyster FS, Aloia MS, Buysse DJ, et al. A couples-oriented intervention for positive airway pressure therapy adherence: a pilot study of obstructive sleep apnea patients and their partners. Behav Sleep Med. 2019 Sep;17(5):561–572.
   PubMed Web of Science ®Google Scholar
• Rosa D, Amigoni C, Rimoldi E, et al. Obstructive sleep apnea and adherence to Continuous Positive Airway Pressure (CPAP) treatment: let’s talk about partners! Healthcare (Basel). 2022 May 19;10(5). DOI:10.3390/healthcare10050943
   Google Scholar
• Baron KG, Gilles A, Sundar KM, et al. Rationale and study protocol for We-PAP: a randomized pilot/feasibility trial of a couples-based intervention to promote PAP adherence and sleep health compared to an educational control. Pilot Feasibility Stud. 2022 Aug 6;8(1):171. DOI:10.1186/s40814-022-01089-x
   PubMedGoogle Scholar
• Catalyst N. What is telehealth? [BRIEF ARTICLE]. NEJM Catal. 2018 2018 Feb 1.
   Google Scholar
• Singh J, Badr MS, Diebert W, et al. American Academy of Sleep Medicine (AASM) position paper for the use of telemedicine for the diagnosis and treatment of sleep disorders. J Clin Sleep Med. 2015 Oct 15;11(10):1187–1198. DOI:10.5664/jcsm.5098
   PubMed Web of Science ®Google Scholar
• Shamim-Uzzaman QA, Bae CJ, Ehsan Z, et al. The use of telemedicine for the diagnosis and treatment of sleep disorders: an American Academy of Sleep Medicine update. J Clin Sleep Med. 2021 May 1;17(5):1103–1107. DOI:10.5664/jcsm.9194
   PubMed Web of Science ®Google Scholar
• Hwang D, Chang JW, Benjafield AV, et al. Effect of telemedicine education and telemonitoring on continuous positive airway pressure adherence. The Tele-OSA randomized trial. Am J Respir Crit Care Med. 2018 Jan 1;197(1):117–126. DOI:10.1164/rccm.201703-0582OC
   PubMed Web of Science ®Google Scholar
• Hwang D. Monitoring progress and adherence with positive airway pressure therapy for obstructive sleep apnea: the roles of telemedicine and mobile health applications. Sleep Med Clin. 2016 Jun;11(2):161–171.
   PubMed Web of Science ®Google Scholar
• Pepin JL, Tamisier R, Hwang D, et al. Does remote monitoring change OSA management and CPAP adherence? Respirology. 2017 Nov;22(8):1508–1517.
   PubMed Web of Science ®Google Scholar
• Olsen S, Smith SS, Oei TP, et al. Motivational interviewing (MINT) improves continuous positive airway pressure (CPAP) acceptance and adherence: a randomized controlled trial. J Consult Clin Psychol. 2012 Feb;80(1):151–163.
   PubMed Web of Science ®Google Scholar
• Schwab RJ, Badr SM, Epstein LJ, et al. An official American thoracic society statement: continuous positive airway pressure adherence tracking systems. The optimal monitoring strategies and outcome measures in adults. Am J Respir Crit Care Med. 2013 Sep 1;188(5):613–620. DOI:10.1164/rccm.201307-1282ST
   PubMed Web of Science ®Google Scholar
• Fox N, Hirsch-Allen AJ, Goodfellow E, et al. The impact of a telemedicine monitoring system on positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial. Sleep. 2012 Apr 1;35(4):477–481. DOI:10.5665/sleep.1728
   PubMed Web of Science ®Google Scholar
• Frasnelli M, Baty F, Niedermann J, et al. Effect of telemetric monitoring in the first 30 days of continuous positive airway pressure adaptation for obstructive sleep apnoea syndrome - a controlled pilot study. J Telemed Telecare. 2016 Jun;22(4):209–214.
   PubMed Web of Science ®Google Scholar
• Turino C, de Batlle J, Woehrle H, et al. Management of continuous positive airway pressure treatment compliance using telemonitoring in obstructive sleep apnoea. Eur Respir J. 2017 Feb;49(2):1601128.
   PubMed Web of Science ®Google Scholar
• Munafo D, Hevener W, Crocker M, et al. A telehealth program for CPAP adherence reduces labor and yields similar adherence and efficacy when compared to standard of care. Sleep Breath. 2016 May;20(2):777–785.
   PubMed Web of Science ®Google Scholar
• Tamisier R, Treptow E, Joyeux-Faure M, et al. Impact of a multimodal telemonitoring intervention on CPAP adherence in symptomatic OSA and low cardiovascular risk: a randomized controlled trial. Chest. 2020 Nov;158(5):2136–2145.
   PubMed Web of Science ®Google Scholar
• Lloyd-Jones DM, Allen NB, Anderson CAM, et al. Life’s essential 8: updating and enhancing the American heart association’s construct of cardiovascular health: a presidential advisory from the American heart association. Circulation. 2022 Aug 2;146(5):e18–43. DOI:10.1161/CIR.0000000000001078
   PubMed Web of Science ®Google Scholar
• Askland K, Wright L, Wozniak DR, et al. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev. 2020 Apr 7;4 CD007736(4). DOI:10.1002/14651858.CD007736.pub3
   PubMedGoogle Scholar