Pneumothorax, pneumomediastinum, and subcutaneous emphysema in hospitalized COVID-19 patients: incidence, clinical characteristics, and outcomes

References

• Ding X, Xu J, Zhou J, et al. Chest CT findings of COVID-19 pneumonia by duration of symptoms. Eur J Radiol. 2020;127:109009. doi: 10.1016/j.ejrad.2020.109009
   PubMed Web of Science ®Google Scholar
• Taha M, Elahi M, Wahby K, et al. Incidence and risk factors of COVID-19 associated pneumothorax. PLoS One. 2022;17(8):e0271964. doi: 10.1371/journal.pone.0271964
   PubMed Web of Science ®Google Scholar
• Chopra A, Al-Tarbsheh AH, Shah NJ, et al. Pneumothorax in critically ill patients with COVID-19 infection: incidence, clinical characteristics and outcomes in a case control multicenter study. Respir med. 2021;184:106464. doi: 10.1016/j.rmed.2021.106464
   PubMed Web of Science ®Google Scholar
• Chong WH, Saha BK, Hu K, et al. The incidence, clinical characteristics, and outcomes of pneumothorax in hospitalized COVID-19 patients: a systematic review. Heart Lung J Crit Care. 2021;50(5):599–608. doi: 10.1016/j.hrtlng.2021.04.005
   PubMed Web of Science ®Google Scholar
• Kanani E. Pneumomediastinum with COVID-19: a natural process or complication? A literature review. Int Surg J. 2020;7(11):3868–3875. doi: 10.18203/2349-2902.isj20204712
   Google Scholar
• Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet Lond Engl. 2020;395(10223):507–513. doi: 10.1016/S0140-6736(20)30211-7
   PubMed Web of Science ®Google Scholar
• Martinelli AW, Ingle T, Newman J, et al. COVID-19 and pneumothorax: a multicentre retrospective case series. Eur Respir J. 2020;56(5):2002697. doi: 10.1183/13993003.02697-2020
   PubMed Web of Science ®Google Scholar
• Muhammad AI, Mehta M, Shaw M, et al. Incidence and clinical features of pneumomediastinum and pneumothorax in COVID-19 pneumonia. J Intensive Care Med. 2022;37(8):1015–1018. doi: 10.1177/08850666221091441
   PubMed Web of Science ®Google Scholar
• Muley M, Finamore P, Pedone C, et al. Incidence and outcome of pneumomediastinum in non-ICU hospitalized COVID-19 patients. Crit Care Med. 2023;51(1):47–56. doi: 10.1097/CCM.0000000000005680
   PubMed Web of Science ®Google Scholar
• Geraci TC, Williams D, Chen S, et al. Incidence, management, and outcomes of patients with COVID-19 and pneumothorax. Ann Thorac Surg. 2022;114(2):401–407. doi: 10.1016/j.athoracsur.2021.07.097
   PubMed Web of Science ®Google Scholar
• Bhakta S, Sanghavi DK, Johnson PW, et al. Clinical and laboratory profiles of the SARS-CoV-2 Delta variant compared with pre-Delta variants. Int J Infect Dis. 2022;120:88–95. doi: 10.1016/j.ijid.2022.04.050
   PubMed Web of Science ®Google Scholar
• Johnson PW, Kunze KL, Senefeld JW, et al. Association of neutralizing antispike monoclonal antibody treatment with coronavirus disease 2019 hospitalization and assessment of the monoclonal antibody screening score. Mayo Clin Proc Innov Qual Outcomes. 2023;7(2):109–121. doi: 10.1016/j.mayocpiqo.2022.12.007
   PubMedGoogle Scholar
• Walkey AJ, Kumar VK, Harhay MO, et al. The viral infection and respiratory illness universal study (VIRUS): an international registry of coronavirus 2019-related Critical illness. Crit Care Explor. 2020;2(4):e0113. doi: 10.1097/CCE.0000000000000113
   PubMedGoogle Scholar
• Walkey AJ, Sheldrick RC, Kashyap R, et al. Guiding principles for the conduct of observational Critical Care research for coronavirus disease 2019 pandemics and beyond: the society of critical care medicine discovery viral infection and respiratory illness universal study registry. Crit Care Med. 2020;48(11):e1038–e1044. doi: 10.1097/CCM.0000000000004572
   PubMed Web of Science ®Google Scholar
• Domecq JP, Lal A, Sheldrick CR, et al. Outcomes of patients with coronavirus disease 2019 receiving organ support therapies: the international viral infection and respiratory illness universal study registry. Crit Care Med. 2021;49(3):437–448. doi: 10.1097/CCM.0000000000004879
   PubMed Web of Science ®Google Scholar
• Tomazini BM, Maia IS, Cavalcanti AB, et al. Effect of dexamethasone on days alive and ventilator-free in patients with moderate or severe acute respiratory distress syndrome and COVID-19: the CoDEX randomized clinical trial. JAMA. 2020;324(13):1307–1316. doi: 10.1001/jama.2020.17021
   PubMed Web of Science ®Google Scholar
• Miró Ò, Llorens P, Jiménez S, et al. Frequency, risk factors, clinical characteristics, and outcomes of spontaneous pneumothorax in patients with coronavirus disease 2019: a case-control, emergency Medicine-based multicenter study. Chest. 2021;159(3):1241–1255. doi: 10.1016/j.chest.2020.11.013
   PubMed Web of Science ®Google Scholar
• McGuinness G, Zhan C, Rosenberg N, et al. Increased incidence of barotrauma in patients with COVID-19 on invasive mechanical ventilation. Radiology. 2020;297(2):E252–E262. doi: 10.1148/radiol.2020202352
   PubMed Web of Science ®Google Scholar
• Lemmers DHL, Abu Hilal M, Bnà C, et al. Pneumomediastinum and subcutaneous emphysema in COVID-19: barotrauma or lung frailty? ERJ Open Res. 2020;6(4):00385–02020. doi: 10.1183/23120541.00385-2020
   PubMedGoogle Scholar
• Cut TG, Tudoran C, Lazureanu VE, et al. Spontaneous pneumomediastinum, pneumothorax, pneumopericardium and subcutaneous emphysema-not so uncommon complications in patients with COVID-19 pulmonary infection-A series of cases. J Clin Med. 2021;10(7):1346. doi: 10.3390/jcm10071346
   PubMed Web of Science ®Google Scholar
• Hyams C, Challen R, Marlow R, et al. Severity of Omicron (B.1.1.529) and Delta (B.1.617.2) SARS-CoV-2 infection among hospitalised adults: a prospective cohort study in Bristol, United Kingdom. Lancet Reg Health - Eur. 2023;25:100556. doi: 10.1016/j.lanepe.2022.100556
   PubMedGoogle Scholar
• Twohig KA, Nyberg T, Zaidi A, et al. Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study. Lancet Infect Dis. 2022;22(1):35–42. doi: 10.1016/S1473-3099(21)00475-8
   PubMed Web of Science ®Google Scholar
• Butt AA, Dargham SR, Chemaitelly H, et al. Severity of illness in persons infected with the SARS-CoV-2 Delta variant vs beta variant in Qatar. JAMA Intern Med. 2022;182((2)):197–205. doi: 10.1001/jamainternmed.2021.7949
   PubMed Web of Science ®Google Scholar
• Zhou C, Gao C, Xie Y, et al. COVID-19 with spontaneous pneumomediastinum. Lancet Infect Dis. 2020;20(4):510. doi: 10.1016/S1473-3099(20)30156-0
   PubMed Web of Science ®Google Scholar
• Wang W, Gao R, Zheng Y, et al. COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema. J Travel Med. 2020;27(5):taaa062. doi: 10.1093/jtm/taaa062
   PubMed Web of Science ®Google Scholar
• Liu K, Zeng Y, Xie P, et al. COVID-19 with cystic features on computed tomography: a case report. Medicine (Baltimore). 2020;99(18):e20175. doi: 10.1097/MD.0000000000020175
   PubMed Web of Science ®Google Scholar
• Ackermann M, Verleden SE, Kuehnel M, et al. Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in covid-19. N Engl J Med. 2020;383(2):120–128. doi: 10.1056/NEJMoa2015432
   PubMed Web of Science ®Google Scholar
• Woodside KJ, vanSonnenberg E, Chon KS, et al. Pneumothorax in patients with acute respiratory distress syndrome: pathophysiology, detection, and treatment. J Intensive Care Med. 2003;18(1):9–20. doi: 10.1177/0885066602239120
   PubMedGoogle Scholar
• Horby P, Lim WS, Haynes R, et al. RECOVERY Collaborative Group. Dexamethasone in hospitalized patients with covid-19. N Engl J Med. 2021;384(8):693–704. doi: 10.1056/NEJMoa2021436.
   PubMed Web of Science ®Google Scholar
• Palumbo D, Campochiaro C, Belletti A, et al. Pneumothorax/Pneumomediastinum in non-intubated COVID-19 patients: differences between first and second Italian pandemic wave. Eur J Intern Med. 2021;88:144–146. doi: 10.1016/j.ejim.2021.03.018
   PubMed Web of Science ®Google Scholar
• Marciniak SJ, Farrell J, Rostron A, et al. COVID-19 pneumothorax in the UK: a prospective observational study using the ISARIC WHO clinical characterisation protocol. Eur Respir J. 2021;58(3):2100929. doi: 10.1183/13993003.00929-2021
   PubMed Web of Science ®Google Scholar