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Original Research

Genetic polymorphisms in CYP2B6 may be associated with lung cancer risk in the Chinese Han population

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Pages 1297-1305 | Received 30 Oct 2023, Accepted 02 Jan 2024, Published online: 04 Jan 2024

References

  • Mattiuzzi C, Lippi G. Current cancer epidemiology. J Epidemiol Glob Health. 2019;9(4):217–222. doi: 10.2991/jegh.k.191008.001
  • Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. Ca A Cancer J Clinicians. 2015;65(2):87–108. doi: 10.3322/caac.21262
  • Hirsch FR, Scagliotti GV, Mulshine JL, et al. Lung cancer: current therapies and new targeted treatments. Lancet (London, England). 2017;389(10066):299–311. doi: 10.1016/S0140-6736(16)30958-8
  • Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the global burden of disease study 2016. Occup Environ Med. 2020;77(3):151–159. doi: 10.1136/oemed-2019-106012
  • Yu D, Zheng W, Johansson M, et al. Overall and central obesity and risk of lung cancer: a pooled analysis. JNCI. 2018;110(8):831–842. doi: 10.1093/jnci/djx286
  • Morel H, Raynard B, d’Arlhac M, et al. Prediagnosis weight loss, a stronger factor than BMI, to predict survival in patients with lung cancer. Lung Cancer. 2018;126:55–63. doi: 10.1016/j.lungcan.2018.07.005
  • O’Keeffe LM, Taylor G, Huxley RR, et al. Smoking as a risk factor for lung cancer in women and men: a systematic review and meta-analysis. BMJ Open. 2018;8(10):e021611. doi: 10.1136/bmjopen-2018-021611
  • Zhao M, Ma J, Li M, et al. Cytochrome P450 enzymes and drug metabolism in humans. Int J Mol Sci. 2021;22(23):12808. doi: 10.3390/ijms222312808
  • Hardwick JP. Cytochrome P450 function and pharmacological roles in inflammation and cancer. Preface. Adv pharmacol (San Diego. Calif). 2015;74:xv–xxxi.
  • Deenen MJ, Cats A, Beijnen JH, et al. Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism. Oncology. 2011;16(6):820–834. doi: 10.1634/theoncologist.2010-0259
  • Liu H, Li G, Sturgis EM, et al. Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck. Int J Cancer. 2022;151(4):553–564. doi: 10.1002/ijc.34023
  • Thum T, Borlak J. Gene expression in distinct regions of the heart. Lancet (London, England). 2000;355(9208):979–983. doi: 10.1016/S0140-6736(00)99016-0
  • Wassenaar CA, Dong Q, Amos CI, et al. Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis. Int J Mol Sci. 2013;14(4):8381–8392. doi: 10.3390/ijms14048381
  • de Araujo TK, Secolin R, Félix TM, et al. A multicentric association study between 39 genes and nonsyndromic cleft lip and palate in a Brazilian population. J Craniomaxillofac Surg. 2016;44(1):16–20. doi: 10.1016/j.jcms.2015.07.026
  • Gola D, Mahachie John JM, van Steen K, et al. A roadmap to multifactor dimensionality reduction methods. Brief Bioinform. 2016;17(2):293–308. doi: 10.1093/bib/bbv038
  • Ritchie MD, Hahn LW, Roodi N, et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet. 2001;69(1):138–147. doi: 10.1086/321276
  • Motsinger AA, Ritchie MD. Multifactor dimensionality reduction: an analysis strategy for modelling and detecting gene-gene interactions in human genetics and pharmacogenomics studies. Hum Genomics. 2006;2(5):318–328. doi: 10.1186/1479-7364-2-5-318
  • Uciechowski P, Imhoff H, Lange C, et al. Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression. J Leukoc Biol. 2011;90(2):377–388. doi: 10.1189/jlb.0409233
  • Huang D, Zhou Y, Yi X, et al. VannoPortal: multiscale functional annotation of human genetic variants for interrogating molecular mechanism of traits and diseases. Nucleic Acids Res. 2022;50(D1):D1408–d1416. doi: 10.1093/nar/gkab853
  • Qiu A, Xu H, Mao L, et al. A novel apaQTL-SNP for the modification of non-small-cell lung cancer susceptibility across histological subtypes. Cancers (Basel). 2022;14(21):5309. doi: 10.3390/cancers14215309
  • Huang Y, Bao T, Zhang T, et al. Machine learning study of SNPs in noncoding regions to predict non-small cell lung cancer susceptibility. Clin Oncol (R Coll Radiol). 2023;35(11):701–712. doi: 10.1016/j.clon.2023.08.010
  • Hurkmans EGE, Klumpers MJ, Vermeulen SH, et al. Analysis of drug metabolizing gene panel in osteosarcoma patients identifies association between variants in SULT1E1, CYP2B6 and CYP4F8 and methotrexate levels and toxicities. Front Pharmacol. 2020;11:1241. doi: 10.3389/fphar.2020.01241
  • Li J, Sun Z, Cui Y, et al. Knockdown of LMNB1 inhibits the proliferation of lung adenocarcinoma cells by inducing DNA damage and cell senescence. Front Oncol. 2022;12:913740. doi: 10.3389/fonc.2022.913740
  • Wang JF, Xi ZN, Su HJ, et al. SP1-induced overexpression of LINC00520 facilitates non-small cell lung cancer progression through miR-577/CCNE2 pathway and predicts poor prognosis. Hum Cell. 2021;34(3):952–964. doi: 10.1007/s13577-021-00518-y
  • Guo G, Li L, Song G, et al. miR‑7/SP1/TP53BP1 axis may play a pivotal role in NSCLC radiosensitivity. Oncol Rep. 2020;44(6):2678–2690. doi: 10.3892/or.2020.7824
  • Zheng X, Sarode P, Weigert A, et al. The HDAC2-SP1 axis orchestrates protumor macrophage polarization. Cancer Res. 2023;83(14):2345–2357. doi: 10.1158/0008-5472.CAN-22-1270
  • Xing YL, Liu F, Li JF, et al. Case-control study on impact of the telomerase reverse transcriptase gene polymorphism and additional single nucleotide polymorphism (SNP)- SNP interaction on non-small cell lung cancers risk in Chinese han population. J Clin Lab Analysis. 2016;30(6):1071–1077. doi: 10.1002/jcla.21982
  • Li Q, Zhang C, Cheng Y, et al. IL1RL1 polymorphisms rs12479210 and rs1420101 are associated with increased lung cancer risk in the Chinese Han population. Front Genet. 2023;14:1183528. doi: 10.3389/fgene.2023.1183528

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