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Original Articles

Sleep-disordered breathing and systemic inflammation in overweight children and adolescents

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Pages 234-239 | Received 08 Aug 2007, Published online: 12 Jul 2009

References

  • Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, et al. Childhood obesity. J Clin Endocrinol Metab. 2005; 903: 1871–87
  • Malik S, Wong ND, Franklin SS, Kamath TV, L'Italien GJ, Pio JR, et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation. 2004; 110(10)1245–50
  • Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB. Low-grade systemic inflammation in overweight children. Pediatrics. 2001; 107(1)E13
  • Cindik N, Baskin E, Agras PI, Kinik ST, Turan M, Saatci U. Effect of obesity on inflammatory markers and renal functions. Acta Paediatr. 2005; 94(12)1732–7
  • Desai MY, Dalal D, Santos RD, Carvalho JA, Nasir K, Blumenthal RS. Association of body mass index, metabolic syndrome, and leukocyte count. Am J Cardiol. 2006; 97(6)835–8
  • Nagasawa N, Tamakoshi K, Yatsuya H, Hori Y, Ishikawa M, Murata C, et al. Association of white blood cell count and clustered components of metabolic syndrome in Japanese men. Circ J. 2004; 68(10)892–7
  • Coller BS. Leukocytosis and ischemic vascular disease morbidity and mortality: is it time to intervene?. Arterioscler Thromb Vasc Biol. 2005; 25(4)658–70
  • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest. 1995; 95(5)2409–15
  • Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab. 1997; 82(12)4196–200
  • Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003; 112(12)1821–30
  • Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW, Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003; 112(12)1796–808
  • Mallory GB, Jr, Fiser DH, Jackson R. Sleep-associated breathing disorders in morbidly obese children and adolescents. J Pediatr. 1989; 115(6)892–7
  • Marcus CL, Curtis S, Koerner CB, Joffe A, Serwint JR, Loughlin GM. Evaluation of pulmonary function and polysomnography in obese children and adolescents. Pediatr Pulmonol. 1996; 21(3)176–83
  • Chay OM, Goh A, Abisheganaden J, Tang J, Lim WH, Chan YH, et al. Obstructive sleep apnea syndrome in obese Singapore children. Pediatr Pulmonol. 2000; 29(4)284–90
  • Verhulst SL, Schrauwen N, Haentjens D, Suys B, Rooman RP, Van Gaal L, et al. Sleep-disordered breathing in overweight and obese children and adolescents: prevalence, characteristics and the role of fat distribution. Arch Dis Child. 2007; 92(3)205–8
  • Verhulst SL, Van Hoeck K, Schrauwen N, Haentjens D, Rooman R, Van Gaal L, et al. Sleep-disordered breathing and uric acid in overweight and obese children and adolescents. Chest. 2007; 132(1)76–80
  • Lavie L. Obstructive sleep apnoea syndrome–an oxidative stress disorder. Sleep Med Rev. 2003; 7(1)35–51
  • Ryan S, Taylor CT, McNicholas WT. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation. 2005; 112(17)2660–7
  • Choi JB, Loredo JS, Norman D, Mills PJ, Ancoli-Israel S, Ziegler MG, et al. Does obstructive sleep apnea increase hematocrit?. Sleep Breath. 2006; 10(3)155–60
  • Yamaguchi Y. Increased number of peripheral leukocytes in patients with severe obstructive sleep apnea-hypopnea syndrome. Sleep and Biological Rhythms. 2006; 4(3)290–2
  • Nacher M, Serrano-Mollar A, Farre R, Panes J, Segui J, Montserrat JM. Recurrent obstructive apneas trigger early systemic inflammation in a rat model of sleep apnea. Respir Physiol Neurobiol. 2007; 155(1)93–6
  • Tauman R, Ivanenko A, O'Brien LM, Gozal D. Plasma C-reactive protein levels among children with sleep-disordered breathing. Pediatrics. 2004; 113(6)e564–9
  • Larkin EK, Rosen CL, Kirchner HL, Storfer-Isser A, Emancipator JL, Johnson NL, et al. Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation. 2005; 111(15)1978–84
  • Kaditis AG, Alexopoulos EI, Kalampouka E, Kostadima E, Angelopoulos N, Germenis A, et al. Morning levels of fibrinogen in children with sleep-disordered breathing. Eur Respir J. 2004; 24(5)790–7
  • Mertens I, Verrijken A, Michiels JJ, Van der Planken M, Ruige JB, Van Gaal LF. Among inflammation and coagulation markers, PAI-1 is a true component of the metabolic syndrome. Int J Obes (Lond) 2006; 30(8)1308–14
  • Deurenberg P, van der Kooy K, Leenen R, Weststrate JA, Seidell JC. Sex and age specific prediction formulas for estimating body composition from bioelectrical impedance: a cross-validation study. Int J Obes. 1991; 15(1)17–25
  • Hauspie R, Roelants M. Growth Charts, Flanders, 2004. Department of Anthropogenetics, Vrije Universiteit Brussel, Belgium; 2004.
  • Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000; 320(7244)1240–3
  • EEG arousals: scoring rules and examples: a preliminary report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep. 1992;15(2):173–84.
  • Mograss MA, Ducharme FM, Brouillette RT. Movement/arousals. Description, classification, and relationship to sleep apnea in children. Am J Respir Crit Care Med. 1994; 150(6 Pt 1)1690–6
  • Traeger N, Schultz B, Pollock AN, Mason T, Marcus CL, Arens R. Polysomnographic values in children 2–9 years old: Additional data and review of the literature. Pediatr Pulmonol. 2005; 40(1)22–30
  • Verhulst SL, Schrauwen N, Haentjens D, Van Gaal L, De Backer WA, Desager KN. Reference values for sleep-related respiratory variables in asymptomatic European children and adolescents. Pediatr Pulmonol. 2007;42(2):159–67.
  • Kutner M, Nachtsheim C, Neter J, Li W. Applied Linear Statistical Models. 5th ed. McGraw-Hill; 2005.
  • Amin RS, Carroll JL, Jeffries JL, Grone C, Bean JA, Chini B, et al. Twenty-four-hour ambulatory blood pressure in children with sleep-disordered breathing. Am J Respir Crit Care Med. 2004; 169(8)950–6
  • Marcus CL, Greene MG, Carroll JL. Blood pressure in children with obstructive sleep apnea. Am J Respir Crit Care Med. 1998; 157(4 Pt 1)1098–103
  • Amin RS, Kimball TR, Bean JA, Jeffries JL, Willging JP, Cotton RT, et al. Left ventricular hypertrophy and abnormal ventricular geometry in children and adolescents with obstructive sleep apnea. Am J Respir Crit Care Med. 2002; 165(10)1395–9
  • Amin RS, Kimball TR, Kalra M, Jeffries JL, Carroll JL, Bean JA, et al. Left ventricular function in children with sleep-disordered breathing. Am J Cardiol. 2005; 95(6)801–4
  • Verhulst SL, Schrauwen N, Haentjens D, Rooman R, Van Gaal L, De Backer W, et al. Sleep-disordered breathing and the metabolic syndrome in overweight and obese children and adolescents. J Pediatr. 2007; 150(6)612–6
  • Redline S, Storfer-Isser A, Rosen CL, Johnson NL, Kirchner HL, Emancipator J, et al. Association Between Metabolic Syndrome and Sleep Disordered Breathing in Adolescents. Am J Respir Crit Care Med. 2007; 176(4)401–8
  • Shamsuzzaman AS, Gersh BJ, Somers VK. Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA. 2003; 290(14)1906–14
  • Kheiradish-Gozal L, Capdevilla OS, Tauman R, Gozal D. Plasma C-reactive protein in nonobese children with obstructive sleep apnea before and after adenotonsillectomy. J Clin Sleep Med. 2006; 3(2)301–4
  • Htoo AK, Greenberg H, Tongia S, Chen G, Henderson T, Wilson D, et al. Activation of nuclear factor kappaB in obstructive sleep apnea: a pathway leading to systemic inflammation. Sleep Breath. 2006; 10(1)43–50
  • O'Brien LM, Serpero LD, Tauman R, Gozal D. Plasma adhesion molecules in children with sleep-disordered breathing. Chest. 2006; 129(4)947–53
  • Kaditis AG, Alexopoulos EI, Kalampouka E, Kostadima E, Germenis A, Zintzaras E, et al. Morning levels of C-reactive protein in children with obstructive sleep-disordered breathing. Am J Respir Crit Care Med. 2005; 171(3)282–6
  • Kelly A, Marcus CL. Childhood obesity, inflammation, and apnea: what is the future for our children?. Am J Respir Crit Care Med. 2005; 171(3)202–3
  • Tauman R, O'Brien LM, Gozal D. Hypoxemia and obesity modulate plasma C-reactive protein and interleukin-6 levels in sleep-disordered breathing. Sleep Breath. 2007; 11(2)77–84
  • von Känel R, Dimsdale JE. Hemostatic alterations in patients with obstructive sleep apnea and the implications for cardiovascular disease. Chest. 2003; 124(5)1956–67
  • Desideri G, De SM, Iughetti L, Rosato T, Iezzi ML, Marinucci MC, et al. Early activation of vascular endothelial cells and platelets in obese children. J Clin Endocrinol Metab. 2005; 90(6)3145–52
  • Haszon I, Papp F, Kovacs J, Bors M, Nemeth I, Bereczki C, et al. Platelet aggregation, blood viscosity and serum lipids in hypertensive and obese children. Eur J Pediatr. 2003; 162(6)385–90
  • Zaldivar F, McMurray RG, Nemet D, Galassetti P, Mills PJ, Cooper DM. Body fat and circulating leukocytes in children. Int J Obes (Lond) 2006; 30(6)906–11
  • Ross R. Atherosclerosis–an inflammatory disease. N Engl J Med. 1999; 340(2)115–26
  • Kapiotis S, Holzer G, Schaller G, Haumer M, Widhalm H, Weghuber D, et al. A proinflammatory state is detectable in obese children and is accompanied by functional and morphological vascular changes. Arterioscler Thromb Vasc Biol. 2006; 26(11)2541–6
  • Meyer AA, Kundt G, Steiner M, Schuff-Werner P, Kienast W. Impaired flow-mediated vasodilation, carotid artery intima-media thickening, and elevated endothelial plasma markers in obese children: the impact of cardiovascular risk factors. Pediatrics. 2006; 117(5)1560–7

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