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Nafa 2006

Lipid-induced cell stress and insulin resistance

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Pages 62-67 | Published online: 13 Dec 2016

References

  • Dahlquist IG, Patterson C, Shaw J, Sicree R, Singh R, Soltesz G, . Diabetes e-atlas; 2005.
  • McGarryJD. What if Minkowski had been ageusic? An alternative angle on diabetesScience199225876670
  • DeFronzoRAGunnarssonRBjorkmanOOlssonMWahrenJ. Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitusJ Clin Invest19857614955
  • SchalchDSKipnisDM. Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acidsJ Clin Invest196544201020
  • UngerRH. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implicationsDiabetes19954486370
  • UngerRHOrciL. Lipotoxic diseases of nonadipose tissues in obesityInt J Obes Relat Metab Disord200024Suppl 4S2832
  • PerseghinGScifoPDe CobelliFPagliatoEBattezzatiAArcelloniC Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H–13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parentsDiabetes19994816006
  • Schrauwen-HinderlingVBKooiMEHesselinkMKMoonen-KornipsESchaartGMustardKJ Intramyocellular lipid content and molecular adaptations in response to a 1-week high-fat dietObes Res200513208894
  • JacobSMachannJRettKBrechtelKVolkARennW Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjectsDiabetes19994811139
  • DobbinsRLSzczepaniakLSBentleyBEsserVMyhillJMcGarryJD. Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in ratsDiabetes20015012330
  • GoodpasterBHHeJWatkinsSKelleyDE. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletesJ Clin Endocrinol Metab200186575561
  • Schrauwen-HinderlingVBSchrauwenPHesselinkMKVan EngelshovenJMNicolayKSarisWH The increase in intramyocellular lipid content is a very early response to trainingJ Clin Endocrinol Metab20038816106
  • KelleyDEMandarinoLJ. Fuel selection in human skeletal muscle in insulin resistance: a reexaminationDiabetes20004967783
  • ItaniSIRudermanNBSchmiederFBodenG. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alphaDiabetes200251200511
  • KimJKFillmoreJJSunshineMJAlbrechtBHigashimoriTKimDW PKC-theta knockout mice are protected from fat-induced insulin resistanceJ Clin Invest20041148237
  • ChavezJASummersSA. Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubesArch Biochem Biophys20034191019
  • VessbyBUnsitupaMHermansenKRiccardiGRivelleseAATapsellLC Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU studyDiabetologia2001443129
  • HoustisNRosenEDLanderES. Reactive oxygen species have a causal role in multiple forms of insulin resistanceNature20064409448
  • HoJKDuclosRIJrHamiltonJA. Interactions of acyl carnitines with model membranes: a 13C-NMR studyJ Lipid Res200243142939
  • RussellAPGastaldiGBobbioni-HarschEArboitPGobeletCDeriazO Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids?FEBS Lett20035511046
  • KelleyDEHeJMenshikovaEVRitovVB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetesDiabetes200251294450
  • PetersenKFDufourSBefroyDGarciaRShulmanGI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetesN Engl J Med200435066471
  • TurrensJF. Superoxide production by the mitochondrial respiratory chainBiosci Rep19971738
  • SkulachevVP. Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductantsQ Rev Biophys199629169202
  • EchtayKSEstevesTCPakayJLJekabsonsMBLambertAJPortero-OtinM A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncouplingEMBO J200322410310
  • HoeksJHesselinkMKSluiterWSchaartGWillemsJMorrissonA The effect of high-fat feeding on intramuscular lipid and lipid peroxidation levels in UCP3-ablated miceFEBS Lett200658013715
  • BrandMDPamplonaRPortero-OtinMRequenaJRRoebuckSJBuckinghamJA Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3Biochem J2002368597603
  • MacLellanJDGerritsMFGowingASmithPJWheelerMBHarperME. Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cellsDiabetes200554234350
  • SchrauwenPMensinkMSchaartGMoonen-KornipsESelsJPBlaakEE Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatmentJ Clin Endocrinol Metab20069115205
  • Mensink M, Hesselink MK, Borghouts LB, Keizer H, Moonen-Kornips E, Schaart G, skeletal muscle uncoupling protein-3 restores upon intervention in the pre-diabetic and diabetic state: implications for diabetes pathogenesis? Diabetes Obes Metab 2006; in press.
  • GableDRStephensJWCooperJAMillerGJHumphriesSE. Variation in the UCP2–UCP3 gene cluster predicts the development of type 2 diabetes in healthy middle-aged menDiabetes200655150411