Significance of psychiatric comorbidity for the outcome of maintenance treatment – a review of the literature

References

• Alterman , A. I. , Rutherford , M. J. , Cacciola , J. S. , McKay , J. R. and Woody , G. E. 1996 . Response to methadone maintenance and counseling in antisocial patients with and without major depression . Journal of Nervous and Mental Disease , 184 : 695 – 702 .
   PubMed Web of Science ®Google Scholar
• Brands , B. , Blake , J. , Marsh , D. C. , Sproule , B. , Jeyapalan , R. and Li , S. 2008 . The impact of benzodiazepine use on methadone maintenance treatment outcomes . Journal of Addictive Disorders , 27 : 37 – 48 .
   PubMed Web of Science ®Google Scholar
• Brooner , R. K. , Greenfield , L. , Schmidt , C. W. and Bigelow , G. E. 1993 . Antisocial personality disorder and HIV infection among intravenous drug abusers . American Journal of Psychiatry , 150 : 53 – 58 .
   PubMed Web of Science ®Google Scholar
• Brooner , R. K. , King , V. L. , Kidorf , M. , Schmidt , C. W., Jr. and Bigelow , G. E. 1997 . Psychiatric and substance use comorbidity among treatment-seeking opioid abusers . Archives of General Psychiatry , 54 : 71 – 80 .
   PubMed Web of Science ®Google Scholar
• Cacciola , J. S. , Alterman , A. I. , Rutherford , M. J. , McKay , J. R. and Mulvaney , F. D. 2001 . The relationship of psychiatric comorbidity to treatment outcomes in methadone maintained patients . Drug and Alcohol Dependence , 61 : 271 – 280 .
   PubMed Web of Science ®Google Scholar
• Cacciola , J. S. , Rutherford , M. J. , Alterman , A. I. , McKay , J. R. and Snider , E. C. 1996 . Personality disorders and treatment outcome in methadone maintenance patients . Journal of Nervous and Mental Disease , 184 : 234 – 239 .
   PubMed Web of Science ®Google Scholar
• Callaly , T. , Trauer , T. , Munro , L. and Whelan , G. 2001 . Prevalence of psychiatric disorder in a methadone maintenance population . Australian and New Zealand Journal of Psychiatry , 35 : 601 – 605 .
   PubMed Web of Science ®Google Scholar
• Carpenter , K. M. , Brooks , A. C. , Vosburg , S. K. and Nunes , E. V. 2004 . The effect of sertraline and environmental context on treating depression and illicit substance use among methadone maintained opiate dependent patients: a controlled clinical trial . Drug and Alcohol Dependence , 74 : 123 – 134 .
   PubMed Web of Science ®Google Scholar
• Compton , W. M. III , Cottler , L. B. , Jacobs , J. L. , Ben-Abdallah , A. and Spitznagel , E. L. 2003 . The role of psychiatric disorders in predicting drug dependence treatment outcomes . American Journal of Psychiatry , 160 : 890 – 895 .
   PubMed Web of Science ®Google Scholar
• Darke , S. , Ross , J. , Williamson , A. , Mills , K. L. , Havard , A. and Teesson , M. 2007 . Borderline personality disorder and persistently elevated levels of risk in 36-month outcomes for the treatment of heroin dependence . Addiction , 102 : 1140 – 1146 .
   PubMed Web of Science ®Google Scholar
• Darke , S. , Swift , W. and Hall , W. 1994 . Prevalence, severity and correlates of psychological morbidity among methadone maintenance clients . Addiction , 89 : 211 – 217 .
   PubMed Web of Science ®Google Scholar
• Darke , S. , Williamson , A. , Ross , J. , Teesson , M. and Lynskey , M. 2004 . Borderline personality disorder, antisocial personality disorder and risk-taking among heroin users: Findings from the Australian Treatment Outcome Study (ATOS) . Drug and Alcohol Dependence , 74 : 77 – 83 .
   PubMed Web of Science ®Google Scholar
• Gelkopf , M. , Weizman , T. , Melamed , Y. , Adelson , M. and Bleich , A. 2006 . Does psychiatric comorbidity affect drug abuse treatment outcome? A prospective assessment of drug abuse, treatment tenure and infectious diseases in an Israeli methadone maintenance clinic . Israel Journal of Psychiatry and Related Sciences , 43 : 126 – 136 .
   PubMed Web of Science ®Google Scholar
• Gerra , G. , Borella , F. , Zaimovic , A. , Moi , G. , Bussandri , M. Bubici , C. 2004 . Buprenorphine versus methadone for opioid dependence: Predictor variables for treatment outcome . Drug and Alcohol Dependence , 75 : 37 – 45 .
   PubMed Web of Science ®Google Scholar
• Gerra , G. , Di Petta , G. , D'Amore , A. , Iannotta , P. , Bardicchia , F. Falorni , F. 2007 . Combination of olanzapine with opioid-agonists in the treatment of heroin addicted patients affected by comorbid schizophrenia spectrum disorders . Clinical Neuropharmacology , 30 : 127 – 135 .
   PubMed Web of Science ®Google Scholar
• Gerra , G. , Ferri , M. , Polidori , E. , Santoro , G. , Zaimovic , A. and Sternieri , E. 2003 . Long-term methadone maintenance effectiveness: Psychosocial and pharmacological variables . Journal of Substance Abuse Treatment , 25 : 1 – 8 .
   PubMed Web of Science ®Google Scholar
• Gerra , G. , Leonardi , C. , D'Amore , A. , Strepparola , G. , Fagetti , R. Assi , C. 2006 . Buprenorphine treatment outcome in dually diagnosed heroin dependent patients: A retrospective study . Progress in Neuro-Psychopharmacology and Biological Psychiatry , 30 : 265 – 272 .
   PubMed Web of Science ®Google Scholar
• Gonzalez , G. , Feingold , A. , Oliveto , A. , Gonsai , K. and Kosten , T. R. 2003 . Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management . American Journal of Drug and Alcohol Abuse , 29 : 497 – 514 .
   PubMed Web of Science ®Google Scholar
• Grella , C. E. , Wugalter , S. E. and Anglin , M. D. 1997 . Predictors of treatment retention in enhanced and standard methadone maintenance treatment for HIV risk reduction . Journal of Drug Issues , 27 : 203 – 224 .
   Web of Science ®Google Scholar
• Havens , J. R. , Latkinm , C. A. , Pu , M. , Cornelius , L. J. , Bishai , D. Huettner , S. 2009 . Predictors of opiate agonist treatment retention among injection drug users referred from a needle exchange program . Journal of Substance Abuse Treatment , 36 : 306 – 312 .
   PubMed Web of Science ®Google Scholar
• Hien , D. A. , Nunes , E. , Levin , F. R. and Fraser , D. 2000 . Posttraumatic stress disorder and short-term outcome in early methadone treatment . Journal of Substance Abuse Treatment , 19 : 31 – 37 .
   PubMed Web of Science ®Google Scholar
• Kamal , F. , Flavin , S. , Campbell , F. , Behan , C. , Fagan , J. and Smyth , R. 2007 . Factors affecting the outcome of methadone maintenance treatment dependence . Irish Medical Journal , 100 : 393 – 397 .
   PubMedGoogle Scholar
• King , V. L. , Kidorf , M. S. , Stoller , K. B. and Brooner , R. K. 2000 . Influence of psychiatric comorbidity on HIV risk behaviors: Changes during drug abuse treatment . Journal of Addictive Diseases , 19 : 65 – 83 .
   PubMed Web of Science ®Google Scholar
• Kleinman , P. H. , Millman , R. B. , Robinson , H. , Lesser , M. , Hsu , C. Engelhart , P. 1994 . Lifetime needle sharing: A predictive analysis . Journal of Substance Abuse Treatment , 11 : 449 – 455 .
   Google Scholar
• Krausz , M. , Degkwitz , P. , Kühne , A. and Verthein , U. 1998 . Comorbidity of opiate dependence and mental disorders . Addictive Behaviors , 23 : 767 – 783 .
   PubMed Web of Science ®Google Scholar
• Lavie , E. , Fatseas , M. , Denis , C. and Auriacombe , M. 2009 . Benzodiazepine use among opiate-dependent subjects in buprenorphine maintenance treatment: correlates of use, abuse and dependence . Drug and Alcohol Dependence , 99 : 338 – 344 .
   PubMed Web of Science ®Google Scholar
• Linehan , M. M. , Dimeff , L. A. , Reynolds , S. K. , Comtois , K. A. , Welch , S. S. Heagerty , P. 2002 . Dialectical behavior therapy versus comprehensive validation therapy plus 12-step for the treatment of opioid dependent women meeting criteria for borderline personality disorder . Drug and Alcohol Dependence , 67 : 13 – 26 .
   PubMed Web of Science ®Google Scholar
• Maremmani , I. , Pacini , M. , Lubrano , S. , Perugi , G. , Tagliamonte , A. Pani , P. P. 2008 . Longterm outcomes of treatment-resistant heroin addicts with and without DSM-IV Axis psychiatric comorbidity (dual diagnosis) . European Addiction Research , 14 : 134 – 142 .
   PubMed Web of Science ®Google Scholar
• McLellan , A. T. , Luborsky , L. , Woody , G. E. , O'Brien , C. P. and Druley , K. A. 1983 . Predicting response to alcohol and drug abuse treatments. Role of psychiatric severity . Archives of General Psychiatry , 40 : 620 – 625 .
   PubMed Web of Science ®Google Scholar
• Musselman , D. L. and Kell , M. J. 1995 . Prevalence and improvement in psychopathology in opioid-dependent patients participating in methadone maintenance . Journal of Addictive Disorders , 14 : 67 – 82 .
   PubMed Web of Science ®Google Scholar
• Nunes , E. V. , Sullivan , M. A. and Levin , F. R. 2004 . Treatment of depression in patients with opiate dependence . Biological Psychiatry , 56 : 793 – 802 .
   PubMed Web of Science ®Google Scholar
• Nunes , E. V. , Quitkin , F. M. , Donovan , S. J. , Deliyannides , D. , Ocepek-Welikson , K. Koeng , T. 1998 . Imipramine treatment of opiate-dependent patients with depressive disorders: A placebo controlled trial . Archives of General Psychiatry , 55 : 153 – 160 .
   PubMed Web of Science ®Google Scholar
• Pani , P. P. , Trogu , E. , Contu , P. , Agus , A. and Gessa , G. L. 1997 . Psychiatric severity and treatment response in a comprehensive methadone maintenance treatment program . Drug and Alcohol Dependence , 48 : 19 – 26 .
   Google Scholar
• Petrakis , I. , Carroll , K. M. , Nichm , C. , Gordon , L. , Kosten , T. and Rounsaville , B. 1998 . Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts . Drug and Alcohol Dependence , 50 : 221 – 226 .
   PubMed Web of Science ®Google Scholar
• Rounsaville , B. J. , Kosten , T. R. , Weissman , M. M. and Kleber , H. D. 1986 . Prognostic significance of psychopathology in treated opiate addicts . Archives of General Psychiatry , 43 : 739 – 745 .
   PubMed Web of Science ®Google Scholar
• Rounsaville , B. J. , Tierney , T. , Crits-Christoph , K. , Weissman , M. M. and Kleber , H. D. 1982 . Predictors of outcome in treatment of opiate addicts: evidence for the multidimensional nature of addicts' problems . Comprehensive Psychiatry , 23 : 462 – 478 .
   PubMed Web of Science ®Google Scholar
• Rounsaville , B. J. , Weissman , M. M. , Crits-Christoph , K. , Wilber , C. and Kleber , H. 1982 . Diagnosis and symptoms of depression in opiate addicts. Course and relationship to treatment outcome . Archives of General Psychiatry , 39 : 151 – 156 .
   PubMed Web of Science ®Google Scholar
• Rutherford , M. J. , Cacciola , J. S. and Alterman , A. I. 1994 . Relationships of personality disorders with problem severity in methadone patients . Drug and Alcohol Dependence , 35 : 69 – 76 .
   PubMed Web of Science ®Google Scholar
• Schäfer , I. , Eiroa , F. , Verthein , U. , Dilg , C. , Haasen , C. and Reimer , J. 2010 . Effects of psychiatric comorbidity on treatment outcome in patients undergoing diamorphine and methadone maintenance treatment . Psychopathology , 43 : 88 – 95 .
   PubMed Web of Science ®Google Scholar
• Schreiber , S. , Peles , E. and Adelson , M. 2008 . Association between improvement in depression, reduced benzodiazepine (BDZ) abuse, and increased psychotropic medication use in methadone maintenance treatment (MMT) patients . Drug and Alcohol Dependence , 92 : 79 – 85 .
   PubMed Web of Science ®Google Scholar
• Strain , E. C. 2002 . Assessment and treatment of comorbid psychiatric disorders in opioid-dependent patients . Clinical Journal of Pain , 18 : 14 – 27 .
   PubMed Web of Science ®Google Scholar
• Strain , E. C. , Brooner , R. K. and Bigelow , G. E. 1991 . Clustering a multiple substance use and psychiatric diagnoses in opiate addicts . Drug and Alcohol Dependence , 27 : 127 – 134 .
   PubMed Web of Science ®Google Scholar
• Teesson , M. , Havard , A. , Fairbairn , S. , Ross , J. , Lynskey , M. and Darke , S. 2005 . Depression among entrants to treatment for heroin dependence in the Australian Treatment Outcome Study (ATOS): prevalence, correlates and treatment seeking . Drug and Alcohol Dependence , 78 : 309 – 315 .
   PubMed Web of Science ®Google Scholar
• Tourian , K. , Alterman , A. , Metzger , D. , Rutherford , M. , Cacciola , J. S. and McKay , J. R. 1997 . Validity of three measures of antisociality in predicting HIV risk behaviors in methadone-maintenance patients . Drug and Alcohol Dependence , 47 : 99 – 107 .
   PubMed Web of Science ®Google Scholar
• Trafton , J. A. , Minkel , J. and Humphreys , K. 2006 . Opioid substitution treatment reduces substance use equivalently in patients with and without posttraumatic stress disorder . Journal of Studies on Alcohol and Drugs , 67 : 228 – 235 .
   PubMed Web of Science ®Google Scholar
• Verthein , U. , Degkwitz , P. , Haasen , C. and Krausz , M. 2005 . Significance of comorbidity for the long-term course of opiate dependence . European Addiction Research , 11 : 15 – 21 .
   PubMed Web of Science ®Google Scholar
• Wedekind , D. , Jacobs , S. , Karg , I. , Luedecke , C. , Schneider , U. & Cimander , K. 2008 . Psychiatric comorbidity and additional abuse of drugs in maintenance treatment with l- and d,l-methadone . World Journal of Biological Psychiatry , 29 : 1 – 10 .
   Google Scholar
• Weizman , T. , Gelkopf , M. , Melamed , Y. , Adelson , M. and Bleich , A. 2003 . Treatment of benzodiazepine dependence in methadone maintenance treatment patients: a comparison of two therapeutic modalities and the role of psychiatric comorbidity . Australian and New Zealand Journal of Psychiatry , 37 : 458 – 463 .
   PubMed Web of Science ®Google Scholar
• Woody , G. E. , Luborsky , L. , McLellan , A. T. , O'Brien , C. P. , Beck , A. T. & Blaine , J. 1983 . Psychotherapy for opiate addicts . Archives of General Psychiatry , 40 : 636 – 645 .
   Google Scholar
• Woody , G. E. , McLellan , A. T. , Luborsky , L. , O'Brien , C. P. , Blaine , J. Fox , S. 1984 . Severity of psychiatric symptoms as a predictor of benefits of psychotherapy: The VA Penn study . American Journal of Psychiatry , 141 : 1172 – 1177 .
   PubMed Web of Science ®Google Scholar
• Woody , G. E. , Metzger , D. , Navaline , H. , McLellan , T. and O'Brien , C. P. 1997 . Psychiatric symptoms, risky behavior, and HIV infection . NIDA Research Monograph , 172 : 156 – 170 .
   PubMedGoogle Scholar
• Zanis , D. A. , Metzger , D. S. and McLellan , A. T. 1994 . Factors associated with employment among methadone patients . Journal of Substance Abuse Treatment , 11 : 443 – 447 .
   PubMed Web of Science ®Google Scholar