Heart rate variability in newborn foals and its association with illness: a pilot study

References

• Armengou L, Monreal L, Tarancón I, Navarro M, Ríos J, Segura D. 2008. Plasma D-dimer concentration in sick newborn foals. J Vet Intern Med. 22(2):411–417.
   PubMed Web of Science ®Google Scholar
• Barsnick RJIM, Hurcombe SDA, Smith PA, Slovis NM, Sprayberry KA, Saville WJA, Toribio RE. 2011. Insulin, glucagon and leptin in critically ill foals. J Vet Int Med. 25(1):123–131.
   PubMed Web of Science ®Google Scholar
• Beuchée A, Carrault G, Bansard JY, Boutaric E, Bétrémieux P, Pladys P. 2009. Uncorrelated randomness of the heart rate is associated with sepsis in sick premature infants. Neonatology. 96(2):109–114.
   PubMed Web of Science ®Google Scholar
• Bohanon FJ, Mrazek AA, Shabana MT, Mims S, Radhakrishnan GL, Kramer GC, Radhakrishnan RS. 2015. Heart rate variability analysis is more sensitive at identifying neonatal sepsis than conventional vital signs. Am J Surg. 210(4):661–667.
   PubMed Web of Science ®Google Scholar
• Bonelli F, Meucci V, Divers T, Radcliffe R, Jose-Cunilleras E, Corazza M, Guidi G, Tognetti R, Castagnetti C, Intorre L, et al. 2015a. Evaluation of plasma procalcitonin concentrations in healthy foals and foals affected by septic systemic inflammatory response syndrome. J Equine Vet Sci. 35(8):645–649.
   Web of Science ®Google Scholar
• Bonelli F, Meucci V, Divers TJ, Jose-Cunilleras E, Corazza M, Tognetti R, Guidi G, Intorre L, Sgorbini M. 2015b. Plasma procalcitonin concentration in healthy horses and horses affected by systemic inflammatory response syndrome. J Vet Intern Med. 29(6):1689–1691.
   PubMed Web of Science ®Google Scholar
• Bonelli F, Meucci V, Divers TJ, Wagner B, Intorre L, Sgorbini M. 2017. Kinetics of plasma procalcitonin, soluble CD14, CCL2 and IL-10 after a sublethal infusion of lipopolysaccharide in horses. Vet Immunol Immunopathol. 184:29–35.
   PubMed Web of Science ®Google Scholar
• Bonjorno Junior JC, Caruso FR, Mendes RG, da Silva TR, Biazon T. M P d C, Rangel F, Phillips SA, Arena R, Borghi-Silva A. 2019. Non invasive measurements of hemodynamic, autonomic and endothelial function as predictors of mortality in sepsis: a prospective cohort study. PLOS One. 14(3):e0213239.
   PubMed Web of Science ®Google Scholar
• Brewer BD, Koterba AM. 1988. Development of a scoring system for the early diagnosis of equine neonatal sepsis. Equine Vet J. 20(1):18–22.
   PubMed Web of Science ®Google Scholar
• Carr EA. 2014. Field triage of the neonatal foal. Vet Clin North Am Equine Pract. 30(2):283–300.
   PubMed Web of Science ®Google Scholar
• Castagnetti C, Veronesi MC. 2008. Prognostic factors in the sick neonatal foal. Vet Res Commun. 32(S1):87–91.
   Web of Science ®Google Scholar
• Corley KTT, Furr MO. 2003. Evaluation of a score designed to predict sepsis in foals. J Vet Emerg Crit Care. 13(3):149–155.
   Web of Science ®Google Scholar
• de Castilho FM, Ribeiro ALP, Nobre V, Barros G, de Sousa MR. 2018. Heart rate variability as predictor of mortality in sepsis: a systematic review. PLoS One. 13(9):e0203487.
   PubMed Web of Science ®Google Scholar
• Fairchild KD, Saucerman JJ, Raynor LL, Sivak JA, Xiao Y, Lake DE, Moorman JR. 2009. Endotoxin depresses heart rate variability in mice: cytokine and steroid effects. Am J Physiol Regul Integr Comp Physiol. 297(4):R1019–R1027.
   PubMed Web of Science ®Google Scholar
• Gold JR, Divers TJ, Barton MH. 2007a. Plasma adrenocorticotropin, cortisol and adenocorticotropin/cortisol ratios in septic and normal-term foals. J Vet Int Med. 21:791–796.
   PubMed Web of Science ®Google Scholar
• Gold JR, Perkins GA, Erb HN, Ainsworth DM. 2007b. Cytokine profiles of peripheral blood mononuclear cells isolated from septic and healthy neonatal foals. J Vet Int Med. 21:481–488.
   Web of Science ®Google Scholar
• Griffin MP, Lake DE, Bissonette EA, Harrell FE, O'Shea TM, Moorman JR. 2005. Heart rate characteristics: novel physiomarkers to predict neonatal infection and death. Pediatrics. 116(5):1070–1074.
   PubMed Web of Science ®Google Scholar
• Hollis AR, Furr MO, Magdesian KG, Axon JE, Ludlow V, Boston RC, Corley KTT. 2008. Blood glucose concentration in critically ill neonatal foals. J Vet Int Med. 22(5):1223–1227.
   PubMed Web of Science ®Google Scholar
• Hurcombe SDA, Toribio RE, Slovis N, Kohn CW, Refsal K, Saville W, Mudge MC. 2008. Blood arginine vasopressin, adrenocorticotropin hormone and cortisol concentrations at admission in septic and critically ill foals and their association with survival. J Vet Int Med. 22(3):639–647.
   PubMed Web of Science ®Google Scholar
• Hurcombe SDA, Toribio RE, Slovis NM, Saville WJ, Mudge MC, MacGillivray K, Frazer ML. 2009. Calcium regulating hormones and serum calcium and magnesium concentrations in septic and critically ill foals and their association with survival. J Vet Int Med. 23(2):335–343.
   PubMed Web of Science ®Google Scholar
• Hytychová T, Bezděková B. 2015. Retrospective evaluation of blood culture isolates and sepsis survival rate in foals in the Czech Republic: 50 cases (2011–2013). Vet Emerg Crit Care. 25(5):660–666.
   PubMed Web of Science ®Google Scholar
• Jarkovska D, Valesova L, Chvojka J, Benes J, Sviglerova J, Florova B, Nalos L, Matejovic M, Stengl M. 2015. Heart rate variability in porcine progressive peritonitis-induced sepsis. Front Physiol. 6:412.
   PubMed Web of Science ®Google Scholar
• Lake DE, Fairchild KD, Moorman JR. 2014. Complex signals bioinformatics: evaluation of heart rate characteristics monitoring as a novel risk marker for neonatal sepsis. J Clin Monit Comput. 28(4):329–339.
   PubMed Web of Science ®Google Scholar
• Lester GD. 2011. Prematurity, dysmaturity and assessment of maturity. In: McKinnon AO, Squires EL, Vaala WE, Varner DD, editors. Equine reproduction. 2nd ed. Wiley-Blackwell, Philadelphia. p. 121–127.
   Google Scholar
• McConachie E, Giguère S, Barton MH. 2016a. Scoring system for multiple organ dysfunction in adult horses with acute surgical gastrointestinal disease. J Vet Intern Med. 30(4):1276–1283.
   PubMed Web of Science ®Google Scholar
• McConachie E, Giguère S, Rapoport G, Barton MH. 2016b. Heart rate variability in horses with acute gastrointestinal disease requiring exploratory laparotomy. J Vet Emerg Crit Care. 26(2):269–280.
   PubMed Web of Science ®Google Scholar
• Nagel C, Erber R, Bergmaier C, Wulf M, Aurich J, Möstl E, Aurich C. 2012. Cortisol and progestin release, heart rate and heart rate variability in the pregnant and postpartum mare, fetus and newborn foal. Theriogenology. 78(4):759–767.
   PubMed Web of Science ®Google Scholar
• Nagel C, Erber R, Ille N, Wulf M, Aurich J, Möstl E, Aurich C. 2015. Heart rate and salivary cortisol concentrations in foals at birth. Vet J. 203(2):250–252.
   PubMed Web of Science ®Google Scholar
• Paltrinieri S, Giordano A, Villani M, Manfrin M, Panzani S, Veronesi MC. 2008. Influence of age and foaling on plasma protein electrophoresis and serum amyloid A and their possible role as markers of equine neonatal septicaemia. Vet J. 176(3):393–396.
   PubMed Web of Science ®Google Scholar
• Peek SF, Darien BJ, Semrad SD, McGuirk S, Lien L, Riseberg A, Marques F, Slack JA, Coombs D. 2004. A prospective study of neonatal septicemia and factors influencing survival. AAEP Proc. 50:60–62.
   Google Scholar
• Prabhakar SM, Tagami T, Liu N, Samsudin MI, Ng JCJ, Koh ZX, Ong MEH. 2019. Combining quick sequential organ failure assessment score with heart rate variability may improve predictive ability for mortality in septic patients at the emergency department. PLOS One. 14(3):e0213445.
   PubMed Web of Science ®Google Scholar
• Pusterla N, Magdesian KG, Mapes S, Leutenegger CM. 2006. Expression of molecular markers in blood of neonatal foals with sepsis. Am J Vet Res. 67(6):1045–1049.
   PubMed Web of Science ®Google Scholar
• Slack JA, McGuirk SM, Erb HN, Lien L, Coombs D, Semrad SD, Riseberg A, Marques F, Darien B, Fallon L, et al. 2005. Biochemical markers of cardiac injury in normal, surviving septic, or nonsurviving septic neonatal foals. J Vet Intern Med. 19(4):577–580.
   PubMed Web of Science ®Google Scholar
• Stoneham SJ. 2006. Assessing the newborn foal. In: Paradis MR, editor. Equine neonatal medicine: a case-based approach. 1st ed. Philadelphia (PA): Elsevier Inc. p. 1–11.
   Google Scholar
• Stucke D, Große Ruse M, Lebelt D. 2015. Measuring heart rate variability in horses to investigate the autonomic nervous system activity – pros and cons of different methods. Appl Anim Behav Sci. 166:1–10.
   Web of Science ®Google Scholar
• Task Force of the European Society of Cardiology, North American Society of Pacing and Electrophysiology. 1996. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Circulation. 93:1043–1065.
   PubMed Web of Science ®Google Scholar
• Taylor S. 2015. A review of equine sepsis. Equine Vet Educ. 27(2):99–109.
   PubMed Web of Science ®Google Scholar
• von Borell E, Langbein J, Després G, Hansen S, Leterrier C, Marchant-Forde J, Marchant-Forde R, Minero M, Mohr E, Prunier A, et al. 2007. Heart rate variability as a measure of autonomic regulation of cardiac activity for assessing stress and welfare in farm animals – a review. Physiol Behav. 92(3):293–316.
   PubMed Web of Science ®Google Scholar
• Vitale V, Viu J, Armengou L, Rìos J, Jose-Cunilleras E. 2020. Prognostic value of measuring heart rate variability at the time of hospital admission in horses with colic. Am J Vet Res. 81(2):147–152.
   PubMed Web of Science ®Google Scholar
• Wilkins PA. 2018. What's in a word? The need for SIRS and sepsis definitions in equine medicine and surgery. Equine Vet J. 50(1):7–9.
   PubMed Web of Science ®Google Scholar
• Wong DM, Wilkins PA. 2015. Defining the systemic inflammatory response syndrome in equine neonates. Vet Clin North Am Equine Pract. 31(3):463–481.
   PubMed Web of Science ®Google Scholar
• Wong DM, Ruby RE, Dembek KA, Barr BS, Reuss SM, Magdesian KG, Olsen E, Burns T, Slovis NM, Wilkins PA. 2018. Evaluation of updated sepsis scoring systems and systemic inflammatory response syndrome criteria and their association with sepsis in equine neonates. J Vet Intern Med. 32(3):1185–1193.
   PubMed Web of Science ®Google Scholar
• Zila I, Mokra D, Kopincova J, Kolomaznik M, Javorka M, Calkovska A. 2015. Heart rate variability and inflammatory response in rats with lipopolysaccharide-induced endotoxemia. Physiol Res. 64(5):S669–S676.
   PubMed Web of Science ®Google Scholar