GenomeAsia100K: Singapore Builds National Science with Asian DNA

References

• The 1000 Genomes Project Consortium. 2010. “A Map of Human Genome Variation from Population-scale Sequencing.” Nature 467 (7319): 1061. doi:10.1038/nature09534.
   PubMed Web of Science ®Google Scholar
• A*STAR. 2019. “Singapore Completes the World’s Largest Whole-genome Sequencing Analysis of Multi-ethnic Asian Populations.” A*STAR Genome Institute of Singapore. Media Release. Accessed 10 January 2020. https://www.a-star.edu.sg/News-and-Events/a-star-news/press-releases/news/press-releases/singapore-completes-world-s-largest-whole-genome-sequencing-analysis-of-multi-ethnic-asian-populations
   Google Scholar
• A*STAR. 2020. “Asian Genomes in the Spotlight.” Accessed 24 February 2020. https://research.a-star.edu.sg/articles/features/asian-genomes-in-the-spotlight/?utm_source=Feb2020-newsletter&utm_medium=email&utm_campaign=Feb2020-newsletter
   Google Scholar
• Benjamin, Ruha. 2009. “A Lab of Their Own: Genomic Sovereignty as Postcolonial Science Policy.” Policy and Society 28 (4): 341–355. doi:10.1016/j.polsoc.2009.09.007.
   Google Scholar
• Bharadwaj, Aditya, and Peter Glasner. 2008. Local Cells, Global Science: The Rise of Embryonic Stem Cell Research in India. London: Routledge.
   Google Scholar
• Burton, Elise K. 2018. “Narrating Ethnicity and Diversity in Middle Eastern National Genome Projects.” Social Studies of Science 48 (5): 762–786. doi:10.1177/0306312718804888.
   Web of Science ®Google Scholar
• Bustamante, Carlos D., M. Francisco, and Esteban G. Burchard. 2011. “Genomics for the World.” Nature 475 (7355): 163–165. doi:10.1038/475163a.
   PubMed Web of Science ®Google Scholar
• Cambon-Thomsen, Anne, Pascal Ducournau, Pierre-Antoine Gourraud, and David Pontille. 2003. “Biobanks for Genomics and Genomics for Biobanks.” International Journal of Genomics 4 (6): 628–634.
   Google Scholar
• Chen, C.H., J.H. Yang, C.W. Chiang, C.N. Hsiung, P.E. Wu, L.C. Chang, H.W. Chu, et al. 2016. “Population Structure of Han Chinese in the Modern Taiwanese Population-based on 10,000 Participants in the Taiwan Biobank Project.” Human Molecular Genetics 25 (24): 5321–5331. doi:10.1093/hmg/ddw346.
   PubMed Web of Science ®Google Scholar
• Chen, Yongxi, and Lingqiao Song. 2018. “China: Concurring Regulation of Cross-border Genomic Data Sharing for Statist Control and Individual Protection.” Human Genetics 137 (8): 605–615. doi:10.1007/s00439-018-1903-2.
   Web of Science ®Google Scholar
• Cho, S.Y., E.J. Hong, J.M. Nam, B. Han, C. Chu, and O. Park. 2012. “Opening of the National Biobank of Korea as the Infrastructure of Future Biomedical Science in Korea.” Osong Public Health and Research Perspectives 3 (3): 177–184. doi:10.1016/j.phrp.2012.07.004.
   Google Scholar
• Clancey, Gregory. 2012. “Intelligent Island to Biopolis: Smart Minds, Sick Bodies, and Millennial Turns in Singapore.” Science, Technology, and Society 17 (1): 13–35. doi:10.1177/097172181101700102.
   Web of Science ®Google Scholar
• Coopmans, Catelijne, and Margaret Tan Ai Hua. 2018. “On ‘Asian’ Distinctiveness and Race as a Variable: The Case of Ophthalmic Epidemiology in Singapore.” Science, Technology, and Society 23 (2): 252–270. doi:10.1177/0971721818762865.
   Web of Science ®Google Scholar
• De Souza, Vanderlei Sebastiao, and Ricardo Ventura Santos. 2014. “The Emergence of Human Population Genetics and Narratives about the Formation of the Brazilian Nation (1950–1960).” Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 47: 97–107. doi:10.1016/j.shpsc.2014.05.010.
   Google Scholar
• de Vries, Jantina, Muminatou Jallow, Thomas N. Williams, Dominic Kwiatkowski, Michael Parker, and Raymond Fitzpatrick. 2012. “Investigating the Potential for Ethnic Group Harm in Collaborative Genomics Research in Africa: Is Ethnic Stigmatization Likely?” Social Science & Medicine 75 (8): 1400–1407. doi:10.1016/j.socscimed.2012.05.020.
   PubMed Web of Science ®Google Scholar
• Dive, L., P. Mason, E. Light, I. Kerridge, and W. Lipworth. 2017. “Globalization and the Ethics of Transnational Biobank Networks.” Asian Bioethics Review 9 (4): 301–310. doi:10.1007/s41649-017-0034-8.
   Google Scholar
• Fakhro, Khalid A., Michelle R. Staudt, Monica Denise Ramstetter, Amal Robay, Joel A. Malek, Ramin Badii, Ajayeb Al-Nabet Al-Marri, et al. 2016. “The Qatar Genome: A Population-specific Tool for Precision Medicine in the Middle East.” Human Genome Variation 3 (1): 1–7. doi:10.1038/hgv.2016.16.
   Google Scholar
• Fischer, Michael MJ. 2013. “Biopolis: Asian Science in the Global Circuitry.” Science, Technology, and Society 18 (3): 379–404. doi:10.1177/0971721813498500.
   Web of Science ®Google Scholar
• Fischer, Michael MJ. 2018. “Theorizing STS from Asia—Toward an STS Multiscale Bioecology Framework: A Blurred Genre Manifesto/Agenda for an Emergent Field.” East Asian Science, Technology and Society: An International Journal 12 (4): 519–540. doi:10.1215/18752160-7219380.
   Web of Science ®Google Scholar
• Fujimura, Joan H. 2000. “Transnational Genomics: Transgressing the Boundary between the ‘Modern/west’ and the ‘Premodern/east’.” In Doing Science+ Culture, edited by Roddey Reid and Sharon Traveek, 71–92. New York: Routledge.
   Google Scholar
• Gelfert, Axel. 2013. “Before Biopolis: Representations of the Biotechnology Discourse in Singapore.” East Asian Science, Technology and Society: An International Journal 7 (1): 103–123. doi:10.1215/18752160-2075527.
   Google Scholar
• GenomeAsia100K. 2019. Genome Asia 100K Sample and Analysis Provider Agreement. By-Law.
   Google Scholar
• GenomeAsia100K Consortium. 2019. “The GenomeAsia 100K Project Enables Genetic Discoveries across Asia.” Nature 576 (7785): 106. doi:10.1038/s41586-019-1793-z.
   Web of Science ®Google Scholar
• Goodwin, Sara, John D. McPherson, and W. Richard McCombie. 2016. “Coming of Age: Ten Years of Next-generation Sequencing Technologies.” Nature Reviews Genetics 17 (6): 333. doi:10.1038/nrg.2016.49.
   PubMed Web of Science ®Google Scholar
• Gurdasani, Deepti, Inês Barroso, Eleftheria Zeggini, and Manjinder S. Sandhu. 2019. “Genomics of Disease Risk in Globally Diverse Populations.” Nature Reviews Genetics 20 (9): 520–535. doi:10.1038/s41576-019-0144-0.
   PubMed Web of Science ®Google Scholar
• H3Africa Consortium. 2014. “Enabling the Genomic Revolution in Africa.” Science 344 (6190): 1346–1348. doi:10.1126/science.1251546.
   Web of Science ®Google Scholar
• Hatch, Anthony Ryan. 2016. Blood Sugar: Racial Pharmacology and Food Justice in Black America. Minneapolis: U of Minnesota Press.
   Google Scholar
• Hindorff, Lucia A., Vence L. Bonham, Lawrence C. Brody, Margaret EC Ginoza, Carolyn M. Hutter, Teri A. Manolio, and Eric D. Green. 2018. “Prioritizing Diversity in Human Genomics Research.” Nature Reviews Genetics 19 (3): 175. doi:10.1038/nrg.2017.89.
   PubMed Web of Science ®Google Scholar
• Hinterberger, Amy. 2012. “Investing in Life, Investing Indifference: Nations, Populations, and Genomes.” Theory, Culture & Society 29 (3): 72–93. doi:10.1177/0263276411427409.
   Web of Science ®Google Scholar
• Hogarth, Stuart. 2007. The Clinical Application of New Molecular Diagnostic Technologies–A Review of the Regulatory and Policy Issues A Report for Health Canada. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH).
   Google Scholar
• International HapMap Consortium. 2003. “The International HapMap Project.” Nature 426 (6968): 789. doi:10.1038/nature02168.
   PubMed Web of Science ®Google Scholar
• Jasanoff, S., ed. 2004. States of Knowledge: The Co-Production of Science and the Social Order. London: Routledge.
   Google Scholar
• Kaiser, D. 2019. “Discovery Is Always Political.” Nature 573: 487–490. doi:10.1038/d41586-019-02848-2.
   Web of Science ®Google Scholar
• Kaye, Jane. 2011. “From Single Biobanks to International Networks: Developing E-governance.” Human Genetics 130 (3): 377. doi:10.1007/s00439-011-1063-0.
   PubMed Web of Science ®Google Scholar
• Lee, Sunhee, Paul Eunil Jung, and Yeonhee Lee. 2016. “Publicly-funded Biobanks and Networks.” East Asia SpringerPlus 5 (1): 1080. doi:10.1186/s40064-016-2723-2.
   Google Scholar
• Lim, Alwyn. 2002. “The Culture of Technology of Singapore.” Asian Journal of Social Science 30 (2): 271–286. doi:10.1163/156853102320405852.
   Google Scholar
• Liu, Jennifer A. 2017. “Postcolonial Biotech: Taiwanese Conundrums and Sub Imperial Desires.” East Asian Science, Technology and Society: An International Journal 11 (4): 563–588. doi:10.1215/18752160-4152424.
   Web of Science ®Google Scholar
• Manry, J., and L. Quintana-Murci. 2013. “A Genome-wide Perspective of Human Diversity and Its Implications in Infectious Disease.” Cold Spring Harbor Perspectives in Medicine 3 (1): 012450. doi:10.1101/cshperspect.a012450.
   PubMed Web of Science ®Google Scholar
• McGonigle, Ian. 2019. “Genomic Data and the Dividual Self.” Genetics Research 101: e12. doi:10.1017/S0016672319000107.
   Web of Science ®Google Scholar
• McGonigle, Ian. 2020a. “National Biobanking in Qatar and Israel: Tracing How Global Scientific Institutions Mediate Local Ethnic Identities.” Science, Technology, and Society 26 (1): 146-165.
   Web of Science ®Google Scholar
• McGonigle, Ian. 2020b. “Biobanking and ‘Qatarization’: Ethno-national Identity in the Molecular Realm.” In Studies on the Social Construction of Identity and Authenticity, edited by KC Schwarz and JP Williams, 156–160. London: Routledge.
   Google Scholar
• McGonigle, Ian, and Stephan C. Schuster. 2018. “Global Science Meets Ethnic Diversity: Ian McGonigle Interviews GenomeAsia100K Scientific Chairman Stephan Schuster.” Genetics Research 101: 1–6.
   Web of Science ®Google Scholar
• McGonigle, Ian Vincent. 2016. “The Collective Nature of Personalized Medicine.” Genetics Research 98 (e3): 1–4. doi:10.1017/S0016672315000270.
   Google Scholar
• McGonigle, Ian Vincent, and Ruha Benjamin. 2016. “The Molecularization of Identity: Science and Subjectivity in the 21st Century.” Genetics Research 98: e12. doi:10.1017/S0016672316000094.
   Web of Science ®Google Scholar
• McGonigle, Ian Vincent, and Noam Shomron. 2016. “Privacy, Anonymity and Subjectivity in Genomic Research.” Genetics Research 98: e2. doi:10.1017/S0016672315000221.
   PubMed Web of Science ®Google Scholar
• Min, Chia Yan. 2014. “A Home for the World’s Best Scientists.” The Straits Times, January 3.
   Google Scholar
• Mitchell, Robert, and Catherine Waldby. 2010. “National Biobanks: Clinical Labor, Risk Production, and the Creation of Biovalue.” Science, Technology, & Human Values 35 (3): 330–355. doi:10.1177/0162243909340267.
   PubMed Web of Science ®Google Scholar
• Nasir, Kamaludeen M., and Bryan S. Turner. 2014. The Future of Singapore: Population, Society and the Nature of the State. New York: Routledge.
   Google Scholar
• Need, Anna C., and David B. Goldstein. 2009. “Next Generation Disparities in Human Genomics: Concerns and Remedies.” Trends in Genetics 25 (1): 489–494. doi:10.1016/j.tig.2009.09.012.
   Google Scholar
• NTU News. 2019. “Asia-wide Genome Mapping Project Reveals Insight into Asian Ancestry and Genetic Diversity.” Accessed 20 March 2020. http://news.ntu.edu.sg/pages/newsdetail.aspx?URL=http://news.ntu.edu.sg/news/Pages/NR2019_Dec05.aspx&Guid=9b2bcb15-d2a7-43a0-8c8d-cbcfc8f486fd&Category=@NTU
   Google Scholar
• OECD. 2010. “Strong Performers and Successful Reformers in Education: Lessons from PISA for the United States: 159–176.” Accessed 23 June 2020. https://www.oecd.org/countries/singapore/46581101.pdf
   Google Scholar
• Ong, Aihwa. 2008. “Scales of Exception: Experiments with Knowledge and Sheer Life in Tropical Southeast Asia.” Singapore Journal of Tropical Geography 29 (2): 117–129. doi:10.1111/j.1467-9493.2008.00323.x.
   Web of Science ®Google Scholar
• Pálsson, Gísli. 2015. “Anthropology, Genomics, and Human Variation: National Roots.” International Encyclopedia of the Social & Behavioral Sciences (2nd ed.), edited by James D. Wright, 758–764.
   Google Scholar
• Pawluk, April. 2019. “National Efforts with Global Implications.” Cell 177 (1): 16–19.
   PubMed Web of Science ®Google Scholar
• Popejoy, Alice B., and Stephanie M. Fullerton. 2016. “Genomics Is Failing on Diversity.” Nature 538: 161–164. doi:10.1038/538161a.
   PubMed Web of Science ®Google Scholar
• Porter, Michael E. 2001. Clusters of Innovation: Regional Foundations of US Competitiveness. Washington, DC: Council on Competitiveness.
   Google Scholar
• PuruShotam, Nirmala Srirekam. 1998. Negotiating Language, Constructing Race: Disciplining in Singapore. Berlin: Mouton de Gruyter.
   Google Scholar
• Raghavan, Maanasa, Matthias Steinrücken, Kelley Harris, Stephan Schiffels, Simon Rasmussen, Michael DeGiorgio, Anders Albrechtsen, et al. 2015. “Genomic Evidence for the Pleistocene and Recent Population History of Native Americans.” Science 349 (6250): aab3884–aab3884. doi:10.1126/science.aab3884.
   PubMed Web of Science ®Google Scholar
• Reardon, Jenny. 2017. The Postgenomic Condition: Ethics, Justice, and Knowledge after the Genome. Chicago: University of Chicago Press.
   Google Scholar
• Reich, David, Kumarasamy Thangaraj, Nick Patterson, Alkes L. Price, and Lalji Singh. 2009. “Reconstructing Indian Population History.” Nature 461 (7263): 489–494. doi:10.1038/nature08365.
   PubMed Web of Science ®Google Scholar
• Rotimi, C.N., and L.B. Jorde. 2010. “Ancestry and Disease in the Age of Genomic Medicine.” New England Journal of Medicine 363 (16): 1551–1558. doi:10.1056/NEJMra0911564.
   PubMed Web of Science ®Google Scholar
• Sleeboom-Faulkner, Margaret. 2018. “The Justification of Studies in Genetic Epidemiology–political Scaling in China Medical City.” Anthropology & Medicine 25 (1): 102–120. doi:10.1080/13648470.2017.1381229.
   PubMed Web of Science ®Google Scholar
• Tan, Augustine HH. 2001. “The Asian Economic Crisis: The Way Ahead for Singapore.” In Singapore Inc.: Public Policy in the Third Millennium, edited by Linda Low and Douglas M. Johnston, 17–34. Singapore: Asia Pacific Press.
   Google Scholar
• Tarkkala, Heta, and Aaro Tupasela. 2018. “Shortcut to Success? Negotiating Genetic Uniqueness in Global Biomedicine.” Social Studies of Science 48 (5): 740–761. doi:10.1177/0306312718801165.
   PubMed Web of Science ®Google Scholar
• Thompson, C. 2010. “Asian Regeneration? Nationalism and Internationalism in Stem Cell Research in South Korea and Singapore.” In Asian Biotech: Ethics and Communities of Fate, edited by Aihwa Ong and Nancy N. Chen, 95–117. Durham, NC: Duke University Press.
   Google Scholar
• Tsai, Yu-yueh. 2010. “Geneticizing Ethnicity: A Study on the ‘Taiwan Bio-Bank’.” East Asian Science, Technology and Society: An International Journal 4 (3): 433–455. doi:10.1215/s12280-010-9146-x.
   Google Scholar
• Tsai, Yu-yueh, and Wan-Ju Lee. 2020. “An Imagined Future Community: Taiwan Biobank, Taiwanese Genome, and Nation-building.” BioSocieties 16: 88–115.
   Web of Science ®Google Scholar
• Waldby, Catherine. 2009. “Singapore Biopolis: Bare Life in the City-state.” East Asian Science, Technology and Society 3 (2–3): 367–383. doi:10.1215/s12280-009-9089-2.
   Google Scholar
• Watson, P.H., R. Ravid, C.B. Eng, J.E. Litton, J. Vaught, and A. Matusan. 2011. “What are the Main Roadblocks to Transnational Biobank Collaboration, and How Can We Overcome Them?” Biopreservation and Biobanking 9 (3): 213–216. doi:10.1089/bio.2011.9340.
   Web of Science ®Google Scholar
• Wu, Degang, Jinzhuang Dou, Xiaoran Chai, Claire Bellis, Andreas Wilm, Chih Chuan Shih, Wendy Wei Jia Soon, et al. 2019. “Large-scale Whole-genome Sequencing of Three Diverse Asian Populations in Singapore.” Cell 179 (3): 736–749. doi:10.1016/j.cell.2019.09.019.
   PubMed Web of Science ®Google Scholar
• Wu, Shellen. 2019. “China: How Science Made a Superpower.” Nature 574 (7776): 25–28. doi:10.1038/d41586-019-02937-2.
   Web of Science ®Google Scholar
• Yangchen, Lin. 2016. “Sequencing 100,000 Asian Genomes for Tailor-made Healthcare.” The Straits Times, April 8.
   Google Scholar
• Yeoh, Keat-Chuan. 2007. “Singapore’s Biomedical Sciences Landscape.” Journal of Commercial Biotechnology 14 (2): 141–148. doi:10.1057/palgrave.jcb.3050083.
   Google Scholar
• Youjin, Low. 2019. “Asians Have at Least 10 Ancestral Lineages, Northern Europeans Just One: NTU-hosted Genetic Study.” Today, December 5.
   Google Scholar
• Zayed, Hatem. 2016. “The Arab Genome: Health and Wealth.” Gene 592 (2): 239–243. doi:10.1016/j.gene.2016.07.007.
   PubMed Web of Science ®Google Scholar
• Zhang, Y., Q. Li, X. Wang, and X. Zhou. 2015. “China Biobanking. In Biobanking in the 21st Century.” Advances in Experimental Medicine and Biology 864: 125–140.
   Web of Science ®Google Scholar
• Zwart, Hub. 2014. “The Donor Organ as an ‘Object A’: A Lacanian Perspective on Organ Donation and Transplantation Medicine.” Medicine, Health Care and Philosophy 17 (4): 559–571. doi:10.1007/s11019-014-9553-1.
   Web of Science ®Google Scholar