Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases

REFERENCES

• Costanzo M, Zurzolo C. The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration. Biochem J 2013; 452(1):1-17; PMID:23614720; http://dx.doi.org/10.1042/BJ20121898
   PubMed Web of Science ®Google Scholar
• Aguzzi A, Falsig J. Prion propagation, toxicity and degradation. Nat Neurosci 2012; 15(7):936-9; PMID:22735515; http://dx.doi.org/10.1038/nn.3120
   PubMed Web of Science ®Google Scholar
• Abounit S, Zurzolo C. Wiring through tunneling nanotubes–from electrical signals to organelle transfer. J Cell Sci 2012; 125(Pt 5):1089-98; PMID:22399801; http://dx.doi.org/10.1242/jcs.083279
   PubMed Web of Science ®Google Scholar
• Rustom A. The missing link: does tunnelling nanotube-based supercellularity provide a new understanding of chronic and lifestyle diseases? Open Biol 2016; 6(6):160057; PMID:27278648; http://dx.doi.org/10.1098/rsob.160057
   PubMed Web of Science ®Google Scholar
• Gousset K, Schiff E, Langevin C, Marijanovic Z, Caputo A, Browman DT, Chenouard N, de Chaumont F, Martino A, Enninga J, et al. Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol 2009; 11(3):328-36; PMID:19198598; http://dx.doi.org/10.1038/ncb1841
   PubMed Web of Science ®Google Scholar
• Costanzo M, Abounit S, Marzo L, Danckaert A, Chamoun Z, Roux P, Zurzolo C. Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes. J Cell Sci 2013; 126(Pt 16):3678-85; PMID:23781027; http://dx.doi.org/10.1242/jcs.126086
   PubMed Web of Science ®Google Scholar
• Abounit S, Bousset L, Loria F, Zhu S, de Chaumont F, Pieri L, Olivo-Marin JC, Melki R, Zurzolo C. Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes. EMBO J 2016; pii: e201593411; [epub ahead of print]
   Google Scholar
• Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G. Cells release prions in association with exosomes. Proc Natl Acad Sci U S A 2004; 101(26):9683-8; PMID:15210972; http://dx.doi.org/10.1073/pnas.0308413101
   PubMed Web of Science ®Google Scholar
• Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, et al. Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J Biol Chem 2012; 287(6):3842-9; PMID:22057275; http://dx.doi.org/10.1074/jbc.M111.277061
   PubMed Web of Science ®Google Scholar
• Münch C, O'Brien J, Bertolotti A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc Natl Acad Sci U S A 2011; 108(9):3548-53; PMID:21321227; http://dx.doi.org/10.1073/pnas.1017275108
   PubMed Web of Science ®Google Scholar
• Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, Kostka M. Different species of α-synuclein oligomers induce calcium influx and seeding. J Neurosci 2007; 27(34):9220-32; PMID:17715357; http://dx.doi.org/10.1523/JNEUROSCI.2617-07.2007
   PubMed Web of Science ®Google Scholar
• Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT, McLean PJ. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. FASEB J 2011; 25(1):326-36; PMID:20876215; http://dx.doi.org/10.1096/fj.10-164624
   PubMed Web of Science ®Google Scholar
• Lee HJ, Suk JE, Bae EJ, Lee JH, Paik SR, Lee SJ. Assembly-dependent endocytosis and clearance of extracellular α-synuclein. Int J Biochem Cell Biol 2008; 40(9):1835-49; PMID:18291704; http://dx.doi.org/10.1016/j.biocel.2008.01.017
   PubMed Web of Science ®Google Scholar
• Lee HJ, Suk JE, Bae EJ, Lee SJ. Clearance and deposition of extracellular α-synuclein aggregates in microglia. Biochem Biophys Res Commun 2008; 372(3):423-8; PMID:18492487; http://dx.doi.org/10.1016/j.bbrc.2008.05.045
   PubMed Web of Science ®Google Scholar
• Ren PH, Lauckner JE, Kachirskaia I, Heuser JE, Melki R, Kopito RR. Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates. Nat Cell Biol 2009; 11(2):219-25; PMID:19151706; http://dx.doi.org/10.1038/ncb1830
   PubMed Web of Science ®Google Scholar
• Frost B, Jacks RL, Diamond MI. Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem 2009; 284(19):12845-52; PMID:19282288; http://dx.doi.org/10.1074/jbc.M808759200
   PubMed Web of Science ®Google Scholar
• Kfoury N, Holmes BB, Jiang H, Holtzman DM, Diamond MI. Trans-cellular propagation of Tau aggregation by fibrillar species. J Biol Chem 2012; 287(23):19440-51; PMID:22461630; http://dx.doi.org/10.1074/jbc.M112.346072
   PubMed Web of Science ®Google Scholar
• Wu JW, Herman M, Liu L, Simoes S, Acker CM, Figueroa H, Steinberg JI, Margittai M, Kayed R, Zurzolo C, et al. Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J Biol Chem 2013; 288(3):1856-70; PMID:23188818; http://dx.doi.org/10.1074/jbc.M112.394528
   PubMed Web of Science ®Google Scholar
• Wu JW, Hussaini SA, Bastille IM, Rodriguez GA, Mrejeru A, Rilett K, Sanders DW, Cook C, Fu H, Boonen RA, et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nat Neurosci 2016; 19(8):1085-92
   PubMed Web of Science ®Google Scholar
• Seng Zhu, Victoria GS, Marzo L, Ghosh R, Zurzolo C. Prion aggregates transfer through tunneling nanotubes in endocytic vesicles. Prion 2015; 9(2):125-135; PMID:25996400; http://dx.doi.org/10.1080/19336896.2015.1025189
   PubMed Web of Science ®Google Scholar
• Abounit S, Delage E, Zurzolo C. Identification and characterization of tunneling nanotubes for intercellular trafficking. Curr Protoc Cell Biol 2015; 67:12.10.1-21; PMID:26061240
   PubMedGoogle Scholar
• Wang Y, Cui J, Sun X, Zhang Y. Tunneling-nanotube development in astrocytes depends on p53 activation. Cell Death Differ 2011; 18(4):732-42; PMID:21113142; http://dx.doi.org/10.1038/cdd.2010.147
   PubMed Web of Science ®Google Scholar
• Chen X, Guo C, Kong J. Oxidative stress in neurodegenerative diseases. Neural Regeneration Res 2012; 7(5):376-85; PMID:25774178
   PubMed Web of Science ®Google Scholar
• Ron D, Hampton RY. Membrane biogenesis and the unfolded protein response. J Cell Biol 2004; 167(1):23-25; PMID:15479733; http://dx.doi.org/10.1083/jcb.200408117
   PubMed Web of Science ®Google Scholar
• Butler D, Bahr BA. Oxidative stress and lysosomes: CNS-related consequences and implications for lysosomal enhancement strategies and induction of autophagy. Antioxidants Redox Signal 2006; 8(1-2):185-96.
   PubMed Web of Science ®Google Scholar
• Chinnery HR, Pearlman E, McMenamin PG. Cutting edge: Membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 2008; 180:5779-83; PMID:18424694; http://dx.doi.org/10.4049/jimmunol.180.9.5779
   PubMed Web of Science ®Google Scholar
• Pyrgaki C, Trainor P, Hadjantonakis AK, Niswander L. Dynamic imaging of mammalian neural tube closure. Dev Biol 2010; 344(2):941-7; PMID:20558153; http://dx.doi.org/10.1016/j.ydbio.2010.06.010
   PubMed Web of Science ®Google Scholar
• Lou E, Fujisawa S, Morozov A, Barlas A, Romin Y, Dogan Y, Gholami S, Moreira AL, Manova-Todorova K, Moore MA. Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. Yang PC, ed. PLoS One 2012; 7(3):e33093; PMID:22427958; http://dx.doi.org/10.1371/journal.pone.0033093
   PubMed Web of Science ®Google Scholar
• Seyed-Razavi Y, Hickey MJ, Kuffová L, McMenamin PG, Chinnery HR. Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction. Immunol Cell Biol 2013; 91(1):89-95; PMID:23146944; http://dx.doi.org/10.1038/icb.2012.52
   PubMed Web of Science ®Google Scholar
• Thayanithy V, Dickson EL, Steer C, Subramanian S, Lou E. Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes. Transl Res 2014; 164(5):359-65; PMID:24929208; http://dx.doi.org/10.1016/j.trsl.2014.05.011
   PubMed Web of Science ®Google Scholar
• Connor Y, Tekleab S, Nandakumar S, Walls C, Tekleab Y, Husain A, Gadish O, Sabbisetti V, Kaushik S, Sehrawat S, et al. Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype. Nat Commun 2015; 6:8671; PMID:26669454; http://dx.doi.org/10.1038/ncomms9671
   PubMed Web of Science ®Google Scholar
• Ady JW, Desir S, Thayanithy V, Vogel RI, Moreira AL, Downey RJ, Fong Y, Manova-Todorova K, Moore MA, Lou E. Intercellular communication in malignant pleural mesothelioma: properties of tunneling nanotubes. Front Physiol 2014; 5:400; PMID:25400582; http://dx.doi.org/10.3389/fphys.2014.00400
   PubMed Web of Science ®Google Scholar
• Polak R, de Rooij B, Pieters R, den Boer ML. B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment. Blood 2015; 126(21):2404-14; PMID:26297738; http://dx.doi.org/10.1182/blood-2015-03-634238
   PubMed Web of Science ®Google Scholar
• Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Blaes J, Weil S, Horstmann H, Wiestler B, Syed M, et al. Brain tumour cells interconnect to a functional and resistant network. Nature 2015; 528(7580):93-8; PMID:26536111
   PubMed Web of Science ®Google Scholar