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Tudor-domain containing proteins act to make the piRNA pathways more robust in Drosophila

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Pages 86-90 | Received 12 Nov 2015, Accepted 30 Nov 2015, Published online: 13 Jan 2016

References

  • Ghildiyal M, Zamore PD. Small silencing RNAs: an expanding universe. Nat Rev Genet 2009; 10:94-108; PMID:19148191; http://dx.doi.org/10.1038/nrg2504
  • Kim VN, Han J, Siomi MC. Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 2009; 10:126-39; PMID:19165215; http://dx.doi.org/10.1038/nrm2632
  • Malone CD, Hannon GJ. Small RNAs as guardians of the genome. Cell 2009; 136:656-68; PMID:19239887; http://dx.doi.org/10.1016/j.cell.2009.01.045
  • Siomi H, Siomi MC. On the road to reading the RNA-interference code. Nature 2009; 457:396-404; PMID:19158785; http://dx.doi.org/10.1038/nature07754
  • Thomson T, Lin H. The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu Rev Cell Dev Biol 2009; 25:355-76; PMID:19575643; http://dx.doi.org/10.1146/annurev.cellbio.24.110707.175327
  • Senti KA, Brennecke J. The piRNA pathway: a fly's perspective on the guardian of the genome. Trends Genet 2010; 26:499-509; PMID:20934772; http://dx.doi.org/: 10.1016/j.tig.2010.08.007
  • Siomi MC, Sato K, Pezic D, Aravin AA. PIWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol 2011; 12:246-58; PMID:21427766; http://dx.doi.org/10.1038/nrm3089
  • Iwasaki YW, Siomi MC, Siomi H. PIWI-Interacting RNA: Its Biogenesis and Functions. Annu Rev Biochem 2015; 84:405-33; PMID:25747396; http://dx.doi.org/10.1146/annurev-biochem-060614-034258
  • Guzzardo PM, Muerdter F, Hannon GJ. The piRNA pathway in flies: highlights and future directions. Curr Opin Genet Dev 2013; 23:44-52; PMID:23317515; http://dx.doi.org/10.1016/j.gde.2012.12.003
  • Lim AK, Kai T. Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci USA 2007; 104:6714-9; PMID:17428915;http://dx.doi.org/10.1073/pnas.0701920104
  • Kirino Y, Kim N, de Planell-Saguer M, Khandros E, Chiorean S, Klein PS, Rigoutsos I, Jongens TA, Mourelatos Z. Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat Cell Biol 2009; 11:652-8; PMID:19377467; http://dx.doi.org/10.1038/ncb1872
  • Nishida KM, Okada TN, Kawamura T, Mituyama T, Kawamura Y, Inagaki S, Huang H, Chen D, Kodama T, Siomi H, et al. Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. EMBO J 2009; 28:3820-31; PMID:19959991; http://dx.doi.org/10.1038/emboj.2009.365
  • Kirino Y, Vourekas A, Sayed N, de Lima Alves F, Thomson T, Lasko P, Rappsilber J, Jongens TA, Mourelatos Z. Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. RNA 2010; 16:70-8; PMID:19926723;http://dx.doi.org/10.1261/rna.1869710
  • Ishizu H, Siomi H, Siomi MC. Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines. Genes Dev 2012; 26:2361-73; PMID:23124062;http://dx.doi.org/10.1101/gad.203786.112
  • Handler D, Meixner K, Pizka M, Lauss K, Schmied C, Gruber FS, Brennecke J. The genetic makeup of the Drosophila piRNA pathway. Mol Cell 2013; 50:762-77; PMID:23665231;http://dx.doi.org/10.1016/j.molcel.2013.04.031
  • Czech B, Preall JB, McGinn J, Hannon GJ. A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway. Mol Cell 2013; 50:749-61; PMID:23665227; http://dx.doi.org/10.1016/j.molcel.2013.04.007
  • Muerdter F, Guzzardo PM, Gillis J, Luo Y, Yu Y, Chen C, Fekete R, Hannon GJ. A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell 2013; 50:736-48;PMID:23665228;http://dx.doi.org/10.1016/j.molcel.2013.04.006
  • Siomi MC, Mannen T, Siomi H. How does the royal family of Tudor rule the PIWI-interacting RNA pathway? Genes Dev 2010; 24:636-46; PMID:20360382; http://dx.doi.org/10.1101/gad.1899210
  • Chen C, Nott TJ, Jin J, Pawson T. Deciphering arginine methylation: Tudor tells the tale. Nat Rev Mol Cell Biol 2011; 12:629-42; PMID:21915143; http://dx.doi.org/10.1038/nrm3185
  • Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, Siomi H, Siomi MC. A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila. Science 2007; 315:1587-90; PMID:17322028;http://dx.doi.org/10.1126/science.1140494
  • Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ. Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 2007; 128:1089-103; PMID:17346786; http://dx.doi.org/10.1016/j.cell.2007.01.043
  • Saito K, Inagaki S, Mituyama T, Kawamura Y, Ono Y, Sakota E, Kotani H, Asai K, Siomi H, Siomi MC. A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature 2009; 461:1296-9; PMID:19812547; http://dx.doi.org/10.1038/nature08501
  • Mohn F, Handler D, Brennecke J. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis. Science 2015; 348:812-7; PMID:25977553;http://dx.doi.org/10.1126/science.aaa1039
  • Han BW, Wang W, Li C, Weng Z, Zamore PD. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production. Science 2015; 348:817-21. PMID:25977554;http://dx.doi.org/10.1126/science.aaa1264
  • Yamanaka S, Siomi MC, Siomi H. piRNA clusters and open chromatin structure. Mob DNA 2014; 5:22; PMID:25126116;http://dx.doi.org/10.1186/1759-8753-5-22
  • Malone CD, Brennecke J, Dus M, Stark A, McCombie WR, Sachidanandam R, Hannon GJ. Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell 2009; 137:522-35; PMID:19395010; http://dx.doi.org/10.1016/j.cell.2009.03.040
  • Li C, Vagin VV, Lee S, Xu J, Ma S, Xi H, Seitz H, Horwich MD, Syrzycka M, Honda BM, et al. Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell 2009; 137:509-21; PMID:19395009; http://dx.doi.org/10.1016/j.cell.2009.04.027
  • Pane A, Wehr K, Schüpbach T. zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. Dev Cell 2007; 12:851-62; PMID:17543859; http://dx.doi.org/:10.1016/j.devcel.2007.03.022
  • Nishimasu H, Ishizu H, Saito K, Fukuhara S, Kamatani MK, Bonnefond L, Matsumoto N, Nishizawa T, Nakanaga K, Aoki J, et al. Structure and function of Zucchini endoribonuclease in piRNA biogenesis. Nature 2012; 491:284-7; PMID:23064230; http://dx.doi.org/10.1038/nature11509
  • Ipsaro JJ, Haase AD, Knott SR, Joshua-Tor L, Hannon GJ. The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature 2012; 491:279-83; PMID:23064227; http://dx.doi.org/10.1038/nature11502
  • Voigt F, Reuter M, Kasaruho A, Schulz EC, Pillai RS, Barabas O. Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc. RNA 2012; 18:2128-34; PMID:23086923;http://dx.doi.org/10.1261/rna.034967.112
  • Klenov MS, Sokolova OA, Yakushev EY, Stolyarenko AD, Mikhaleva EA, Lavrov SA, Gvozdev VA. Separation of stem cell maintenance and transposon silencing functions of Piwi protein. Proc Natl Acad Sci USA 2011; 108:18760-5; PMID:22065765;http://dx.doi.org/10.1073/pnas.1106676108
  • Sienski G, Dönertas D, Brennecke J. Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression. Cell. 2012; 151:964-80; PMID:23159368; http://dx.doi.org/10.1016/j.cell.2012.10.040
  • Rozhkov NV, Hammell M, Hannon GJ. Multiple roles for Piwi in silencing Drosophila transposons. Genes Dev 2013; 27:400-12; PMID:23392609; http://dx.doi.org/10.1101/gad.209767.112
  • Le Thomas A, Rogers AK, Webster A, Marinov GK, Liao SE, Perkins EM, Hur JK, Aravin AA, Tóth KF. Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. Genes Dev 2013; 27:390-9; PMID:23392610; http://dx.doi.org/10.1101/gad.209841.112
  • Nishida KM, Saito K, Mori T, Kawamura Y, Nagami-Okada T, Inagaki S, Siomi H, Siomi MC. Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad. RNA 2007; 13:1911-22; PMID:17872506; http://dx.doi.org/10.1261/rna.744307
  • Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z, Cora E, Couté Y, Conn S, Kadlec J, Sachidanandam R, et al. RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts. Cell 2014; 157:1698-711; PMID:24910301; http://dx.doi.org/10.1016/j.cell.2014.05.018
  • Nishida KM, Iwasaki YW, Murota Y, Nagao A, Mannen T, Kato Y, Siomi H, Siomi MC. Respective functions of two distinct Siwi complexes assembled during PIWI-interacting RNA biogenesis in Bombyx germ cells. Cell Rep 2015; 10:193-203; PMID:25558067; http://dx.doi.org/10.1016/j.celrep.2014.12.013
  • Wang W, Han BW, Tipping C, Ge DT, Zhang Z, Weng Z, Zamore PD. Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms. Mol Cell 2015; 59:819-30; PMID:26340424; http://dx.doi.org/10.1016/j.molcel.2015.08.007
  • Senti KA, Jurczak D, Sachidanandam R, Brennecke J. piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire. Genes Dev 2015; 29:1747-62; PMID:26302790;http://dx.doi.org/10.1101/gad.267252.115
  • Nagao A, Sato K, Nishida KM, Siomi H, Siomi MC. Gender-Specific Hierarchy in Nuage Localization of PIWI-Interacting RNA Factors in Drosophila. Front Genet 2011; 2:55; PMID:22303351; http://dx.doi.org/10.3389/fgene.2011.00055
  • Sato K, Iwasaki YW, Shibuya A, Carninci P, Tsuchizawa Y, Ishizu H, Siomi MC, Siomi H. Krimper Enforces an Antisense Bias on piRNA Pools by Binding AGO3 in the Drosophila Germline. Mol Cell 2015; 59:553-63; PMID:26212455; http://dx.doi.org/10.1016/j.molcel.2015.06.024
  • Webster A, Li S, Hur JK, Wachsmuth M, Bois JS, Perkins EM, Patel DJ, Aravin AA. Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper. Mol Cell 2015; 59:564-75; PMID:26295961; http://dx.doi.org/10.1016/j.molcel.2015.07.017
  • Olivieri D, Senti KA, Subramanian S, Sachidanandam R, Brennecke J. The cochaperone shutdown defines a group of biogenesis factors essential for all piRNA populations in Drosophila. Mol Cell 2012; 47:954-69; PMID:22902557; http://dx.doi.org/10.1016/j.molcel.2012.07.021
  • Zhang Z, Xu J, Koppetsch BS, Wang J, Tipping C, Ma S, Weng Z, Theurkauf WE, Zamore PD. Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Mol Cell 2011; 44:572-84; PMID:22099305;http://dx.doi.org/10.1016/j.molcel.2011.10.011
  • Anand A, Kai T. The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila. EMBO J 2012; 31:870-82; PMID:22157814;http://dx.doi.org/10.1038/emboj.2011.449
  • Zhang Z, Koppetsch BS, Wang J, Tipping C, Weng Z, Theurkauf WE, Zamore PD. Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin. EMBO J 2014; 33:536-9; PMID:24652836; http://dx.doi.org/10.1002/embj.201384895
  • Brennecke J, Malone CD, Aravin AA, Sachidanandam R, Stark A, Hannon GJ. An epigenetic role for maternally inherited piRNAs in transposon silencing. Science 2008; 322:1387-92; PMID:19039138; http://dx.doi.org/10.1126/science.1165171
  • Le Thomas A, Stuwe E, Li S, Du J, Marinov G, Rozhkov N, Chen YC, Luo Y, Sachidanandam R, Toth KF, et al. Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev 2014; 28:1667-80; PMID:25085419; http://dx.doi.org/10.1101/gad.245514.114

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