Gain-of-function nature of Cav1.4 L-type calcium channels alters firing properties of mouse retinal ganglion cells

References

• Strom TM, Nyakatura G, Apfelstedt-Sylla E, Hellebrand H, Lorenz B, Weber BH, Wutz K, Gutwillinger N, Ruther K, Drescher B, et al. An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness. NatGenet 1998; 19:260-3
   Google Scholar
• Boycott KM, Pearce WG, Musarella MA, Weleber RG, Maybaum TA, Birch DG, Miyake Y, Young RS, Bech-Hansen NT. Evidence for genetic heterogeneity in X-linked congenital stationary night blindness. Am J Hum Genet 1998; 62:865-75; PMID:9529339; http://dx.doi.org/10.1086/301781
   PubMed Web of Science ®Google Scholar
• Stockner T, Koschak A. What can naturally occurring mutations tell us about Ca(v)1.x channel function? Biochim Biophys Acta 2013; 1828:1598-607; PMID:23219801; http://dx.doi.org/10.1016/j.bbamem.2012.11.026
   PubMed Web of Science ®Google Scholar
• Zeitz C, Robson AG, Audo I. Congenital stationary night blindness: an analysis and update of genotype-phenotype correlations and pathogenic mechanisms. Prog Retin Eye Res 2015; 45:58-110; PMID:25307992; http://dx.doi.org/10.1016/j.preteyeres.2014.09.001
   PubMed Web of Science ®Google Scholar
• Morgans CW, Gaughwin P, Maleszka R. Expression of the alpha1F calcium channel subunit by photoreceptors in the rat retina. Mol Vis 2001; 7:202-9; PMID:11526344
   PubMed Web of Science ®Google Scholar
• Specht D, Wu SB, Turner P, Dearden P, Koentgen F, Wolfrum U, Maw M, Brandstatter JH, tom Dieck S. Effects of presynaptic mutations on a postsynaptic Cacna1s calcium channel colocalized with mGluR6 at mouse photoreceptor ribbon synapses. Invest Ophthalmol Vis Sci 2009; 50:505-15; PMID:18952919; http://dx.doi.org/10.1167/iovs.08-2758
   PubMed Web of Science ®Google Scholar
• Koschak A, Reimer D, Walter D, Hoda JC, Heinzle T, Grabner M, Striessnig J. Cav1.4a1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation. J Neurosci 2003; 23:6041-9; PMID:12853422
   PubMed Web of Science ®Google Scholar
• Mansergh F, Orton NC, Vessey JP, Lalonde MR, Stell WK, Tremblay F, Barnes S, Rancourt DE, Bech-Hansen NT. Mutation of the calcium channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina. Hum Mol Genet 2005; 14:3035-46; PMID:16155113; http://dx.doi.org/10.1093/hmg/ddi336
   PubMed Web of Science ®Google Scholar
• Miyake Y, Yagasaki K, Horiguchi M, Kawase Y, Kanda T. Congenital stationary night blindness with negative electroretinogram. A new classification. Arch Ophthalmol 1986; 104:1013-20; PMID:3488053; http://dx.doi.org/10.1001/archopht.1986.01050190071042
   PubMed Web of Science ®Google Scholar
• Knoflach D, Kerov V, Sartori SB, Obermair GJ, Schmuckermair C, Liu X, Sothilingam V, Garrido MG, Baker SA, Glosmann M, et al. Cav1.4 IT mouse as model for vision impairment in human congenital stationary night blindness type 2. Channels (Austin) 2013; 7:503-13; PMID:24051672; http://dx.doi.org/10.4161/chan.26368
   PubMed Web of Science ®Google Scholar
• Zabouri N, Haverkamp S. Calcium channel-dependent molecular maturation of photoreceptor synapses. PLoS One 2013; 8:e63853; PMID:23675510; http://dx.doi.org/10.1371/journal.pone.0063853
   PubMed Web of Science ®Google Scholar
• Liu X, Kerov V, Haeseleer F, Majumder A, Artemyev N, Baker SA, Lee A. Dysregulation of Ca(v)1.4 channels disrupts the maturation of photoreceptor synaptic ribbons in congenital stationary night blindness type 2. Channels (Austin) 2013; 7:514-23; PMID:24064553; http://dx.doi.org/10.4161/chan.26376
   PubMed Web of Science ®Google Scholar
• Regus-Leidig H, Atorf J, Feigenspan A, Kremers J, Maw MA, Brandstatter JH. Photoreceptor degeneration in two mouse models for congenital stationary night blindness type 2. PLoS One 2014; 9:e86769; PMID:24466230; http://dx.doi.org/10.1371/journal.pone.0086769
   PubMed Web of Science ®Google Scholar
• Michalakis S, Shaltiel L, Sothilingam V, Koch S, Schludi V, Krause S, Zeitz C, Audo I, Lancelot ME, Hamel C, et al. Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2. Hum Mol Genet 2014; 23:1538-50; PMID:24163243; http://dx.doi.org/10.1093/hmg/ddt541
   PubMed Web of Science ®Google Scholar
• Dick O, tom Dieck S, Altrock WD, Ammermuller J, Weiler R, Garner CC, Gundelfinger ED, Brandstatter JH. The presynaptic active zone protein bassoon is essential for photoreceptor ribbon synapse formation in the retina. Neuron 2003; 37:775-86; PMID:12628168; http://dx.doi.org/10.1016/S0896-6273(03)00086-2
   PubMed Web of Science ®Google Scholar
• Doering CJ, Rehak R, Bonfield S, Peloquin JB, Stell WK, Mema SC, Sauve Y, McRory JE. Modified Ca(v)1.4 expression in the Cacna1f(nob2) mouse due to alternative splicing of an ETn inserted in exon 2. PLoS One 2008; 3:e2538; PMID:18596967; http://dx.doi.org/10.1371/journal.pone.0002538
   PubMed Web of Science ®Google Scholar
• Chang B, Heckenlively JR, Bayley PR, Brecha NC, Davisson MT, Hawes NL, Hirano AA, Hurd RE, Ikeda A, Johnson BA, et al. The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses. Vis Neurosci 2006; 23:11-24; PMID:16597347; http://dx.doi.org/10.1017/S095252380623102X
   PubMed Web of Science ®Google Scholar
• Hemara-Wahanui A, Berjukow S, Hope CI, Dearden PK, Wu SB, Wilson-Wheeler J, Sharp DM, Lundon-Treweek P, Clover GM, Hoda JC, et al. A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation. Proc Natl Acad Sci U S A 2005; 102:7553-8; PMID:15897456; http://dx.doi.org/10.1073/pnas.0501907102
   PubMed Web of Science ®Google Scholar
• Nirenberg S, Meister M. The light response of retinal ganglion cells is truncated by a displaced amacrine circuit. Neuron 1997; 18:637-50; PMID:9136772; http://dx.doi.org/10.1016/S0896-6273(00)80304-9
   PubMed Web of Science ®Google Scholar
• Enroth-Cugell C, Robson JG. The contrast sensitivity of retinal ganglion cells of the cat. J Physiol 1966; 187:517-52; PMID:16783910; http://dx.doi.org/10.1113/jphysiol.1966.sp008107
   PubMed Web of Science ®Google Scholar
• Umino Y, Solessio E, Barlow RB. Speed, spatial, and temporal tuning of rod and cone vision in mouse. J Neurosci 2008; 28:189-98; PMID:18171936; http://dx.doi.org/10.1523/JNEUROSCI.3551-07.2008
   PubMed Web of Science ®Google Scholar
• Bijveld MM, Florijn RJ, Bergen AA, van den Born LI, Kamermans M, Prick L, Riemslag FC, van Schooneveld MJ, Kappers AM, van Genderen MM. Genotype and phenotype of 101 dutch patients with congenital stationary night blindness. Ophthalmology 2013; 120:2072-81; PMID:23714322; http://dx.doi.org/10.1016/j.ophtha.2013.03.002
   PubMed Web of Science ®Google Scholar
• Blanks JC, Johnson LV. Selective lectin binding of the developing mouse retina. J Comp Neurol 1983; 221:31-41; PMID:6643744; http://dx.doi.org/10.1002/cne.902210103
   PubMed Web of Science ®Google Scholar
• Peng YW, Hao Y, Petters RM, Wong F. Ectopic synaptogenesis in the mammalian retina caused by rod photoreceptor-specific mutations. Nat Neurosci 2000; 3:1121-7; PMID:11036269; http://dx.doi.org/10.1038/80639
   PubMed Web of Science ®Google Scholar
• Strettoi E, Pignatelli V. Modifications of retinal neurons in a mouse model of retinitis pigmentosa. Proc Natl Acad Sci U S A 2000; 97:11020-5; PMID:10995468; http://dx.doi.org/10.1073/pnas.190291097
   PubMed Web of Science ®Google Scholar
• Haverkamp S, Wassle H. Immunocytochemical analysis of the mouse retina. J Comp Neurol 2000; 424:1-23; PMID:10888735; http://dx.doi.org/10.1002/1096-9861(20000814)424:1%3c1::AID-CNE1%3e3.0.CO;2-V
   PubMed Web of Science ®Google Scholar
• Bloomfield SA, Volgyi B. The diverse functional roles and regulation of neuronal gap junctions in the retina. Nat Rev Neurosci 2009; 10:495-506; PMID:19491906; http://dx.doi.org/10.1038/nrn2636
   PubMed Web of Science ®Google Scholar
• Deans MR, Volgyi B, Goodenough DA, Bloomfield SA, Paul DL. Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron 2002; 36:703-12; PMID:12441058; http://dx.doi.org/10.1016/S0896-6273(02)01046-2
   PubMed Web of Science ®Google Scholar
• Krizaj D, Copenhagen DR. Calcium regulation in photoreceptors. Front Biosci 2002; 7:d2023-44; PMID:12161344; http://dx.doi.org/10.2741/krizaj
   PubMed Web of Science ®Google Scholar
• Krizaj D, Demarco SJ, Johnson J, Strehler EE, Copenhagen DR. Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons. J Comp Neurol 2002; 451:1-21; PMID:12209837; http://dx.doi.org/10.1002/cne.10281
   PubMed Web of Science ®Google Scholar
• Haverkamp S, Ghosh KK, Hirano AA, Wassle H. Immunocytochemical description of five bipolar cell types of the mouse retina. J Comp Neurol 2003; 455:463-76; PMID:12508320; http://dx.doi.org/10.1002/cne.10491
   PubMed Web of Science ®Google Scholar
• Tom Dieck S. Keeping the balance. Channels (Austin) 2013; 7:418-9; PMID:24722264; http://dx.doi.org/10.4161/chan.26925
   PubMed Web of Science ®Google Scholar
• Morgans CW. Localization of the α(1F) calcium channel subunit in the rat retina. Invest Ophthalmol Vis Sci 2001; 42:2414-8; PMID:11527958
   PubMed Web of Science ®Google Scholar
• Berntson A, Taylor WR, Morgans CW. Molecular identity, synaptic localization, and physiology of calcium channels in retinal bipolar cells. J Neurosci Res 2003; 71:146-51; PMID:12478624; http://dx.doi.org/10.1002/jnr.10459
   PubMed Web of Science ®Google Scholar
• Busquet P, Nguyen NK, Schmid E, Tanimoto N, Seeliger MW, Ben-Yosef T, Mizuno F, Akopian A, Striessnig J, Singewald N. CaV1.3 L-type Ca2+ channels modulate depression-like behaviour in mice independent of deaf phenotype. Int J Neuropsychopharmacol 2010; 13:499-513; PMID:19664321; http://dx.doi.org/10.1017/S1461145709990368
   PubMed Web of Science ®Google Scholar
• Sonntag S, Dedek K, Dorgau B, Schultz K, Schmidt KF, Cimiotti K, Weiler R, Lowel S, Willecke K, Janssen-Bienhold U. Ablation of retinal horizontal cells from adult mice leads to rod degeneration and remodeling in the outer retina. J Neurosci 2012; 32:10713-24; PMID:22855819; http://dx.doi.org/10.1523/JNEUROSCI.0442-12.2012
   PubMed Web of Science ®Google Scholar
• Li ZY, Kljavin IJ, Milam AH. Rod photoreceptor neurite sprouting in retinitis pigmentosa. J Neurosci 1995; 15:5429-38; PMID:7643192
   PubMed Web of Science ®Google Scholar
• Fisher SK, Lewis GP, Linberg KA, Verardo MR. Cellular remodeling in mammalian retina: results from studies of experimental retinal detachment. Prog Retin Eye Res 2005; 24:395-431; PMID:15708835; http://dx.doi.org/10.1016/j.preteyeres.2004.10.004
   PubMed Web of Science ®Google Scholar
• Liets LC, Eliasieh K, van der List DA, Chalupa LM. Dendrites of rod bipolar cells sprout in normal aging retina. Proc Natl Acad Sci U S A 2006; 103:12156-60; PMID:16880381; http://dx.doi.org/10.1073/pnas.0605211103
   PubMed Web of Science ®Google Scholar
• Raven MA, Orton NC, Nassar H, Williams GA, Stell WK, Jacobs GH, Bech-Hansen NT, Reese BE. Early afferent signaling in the outer plexiform layer regulates development of horizontal cell morphology. J Comp Neurol 2008; 506:745-58; PMID:18076080; http://dx.doi.org/10.1002/cne.21526
   PubMed Web of Science ®Google Scholar
• Dunn FA. Photoreceptor ablation initiates the immediate loss of glutamate receptors in postsynaptic bipolar cells in retina. J Neurosci 2015; 35:2423-31; PMID:25673837; http://dx.doi.org/10.1523/JNEUROSCI.4284-14.2015
   PubMed Web of Science ®Google Scholar
• Puthussery T, Gayet-Primo J, Pandey S, Duvoisin RM, Taylor WR. Differential loss and preservation of glutamate receptor function in bipolar cells in the rd10 mouse model of retinitis pigmentosa. Eur J Neurosci 2009; 29:1533-42; PMID:19385989; http://dx.doi.org/10.1111/j.1460-9568.2009.06728.x
   PubMed Web of Science ®Google Scholar
• Feigenspan A, Janssen-Bienhold U, Hormuzdi S, Monyer H, Degen J, Sohl G, Willecke K, Ammermuller J, Weiler R. Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci 2004; 24:3325-34; PMID:15056712; http://dx.doi.org/10.1523/JNEUROSCI.5598-03.2004
   PubMed Web of Science ®Google Scholar
• Xing W, Akopian A, Krizaj D. Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 alpha1 subunits. Adv Exp Med Biol 2012; 723:739-44; PMID:22183401; http://dx.doi.org/10.1007/978-1-4614-0631-0_94
   PubMed Web of Science ®Google Scholar
• Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nat Methods 2012; 9:671-5; PMID:22930834; http://dx.doi.org/10.1038/nmeth.2089
   PubMed Web of Science ®Google Scholar
• Straw AD. Vision egg: an open-source library for realtime visual stimulus generation. Frontiers in neuroinformatics 2008; 2:4; PMID:19050754; http://dx.doi.org/10.3389/neuro.11.004.2008
   PubMedGoogle Scholar
• Quiroga RQ, Nadasdy Z, Ben-Shaul Y. Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering. Neural computation 2004; 16:1661-87; PMID:15228749; http://dx.doi.org/10.1162/089976604774201631
   PubMed Web of Science ®Google Scholar
• Wiltschko AB, Gage GJ, Berke JD. Wavelet filtering before spike detection preserves waveform shape and enhances single-unit discrimination. J Neurosci Methods 2008; 173:34-40; PMID:18597853; http://dx.doi.org/10.1016/j.jneumeth.2008.05.016
   PubMed Web of Science ®Google Scholar