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Autocommentary

Impaired cAMP-cGMP cross-talk during cardiac sympathetic dysautonomia

Emma N. BardsleyWellcome Trust OXION Initiative in Ion Channels and Disease, Oxford, UK;Burdon Sanderson Cardiac Science Center, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UKCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-3371-1290
ORCID Icon,
Hege E. LarsenWellcome Trust OXION Initiative in Ion Channels and Disease, Oxford, UK;Burdon Sanderson Cardiac Science Center, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
&
David J. PatersonWellcome Trust OXION Initiative in Ion Channels and Disease, Oxford, UK;Burdon Sanderson Cardiac Science Center, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
Pages 178-180 | Received 04 Nov 2016, Accepted 04 Nov 2016, Published online: 18 Dec 2016

References

  • Malpas SC. Sympathetic nervous system overactivity and its role in the development of cardiovascular disease. Phys Revs 2010; 90(2):513-557; PMID:20393193; https://doi.org/10.1152/physrev.00007.2009
  • Yamada Y, Kinoshita H, Kuwahara K, Nakagawa Y, Kuwabara Y, Minami T, Yamada C, Shibata J, Nakao K, Cho K, et al. Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure. Cardiovasc Res 2014; 104(1):183-193; PMID:25100767; https://doi.org/10.1093/cvr/cvu185
  • Li D, Paterson DJ. Cyclic nucleotide regulation of cardiac sympatho-vagal responsiveness. J Physiol 2016; 594(14):3993-4008; PMID:26915722; https://doi.org/10.1113/JP271827
  • Larsen HE, Bardsley EN, Lefkimmiatis K, Paterson DJ. Dysregulation of neuronal Ca2+ channel linked to heightened sympathetic phenotype in prohypertensive states. J. Neurosci 2016; 36(33):8562-73; PMID:27535905; https://doi.org/10.1523/JNEUROSCI.1059-16.2016
  • Zaccolo M, Movsesian MA. cAMP and cGMP signaling cross-talk: Role of Phosphodiesterases and implications for cardiac pathophysiology. Circ Res 2007; 100(11):1569-78; PMID:17556670; https://doi.org/10.1161/CIRCRESAHA.106.144501
  • Li D, Lu CJ, Hao G, Wright H, Woodward L, Liu K, Vergari E, Surdo NC, Herring N, Zaccolo M, et al. Efficacy of B-type natriuretic peptide is coupled to phosphodiesterase 2A in cardiac sympathetic neurons. Hypertension 2015; 66(1):190-8; PMID:25916722; https://doi.org/10.1161/HYPERTENSIONAHA.114.05054
  • Boda H, Uchida H, Takaiso N, Ouchi Y, Fujita N, Kuno A, Hata T, Nagatani A, Funamoto Y, Miyata M, et al. A PDE3A mutation in familial hypertension and brachydactyly syndrome. J Hum Genet 2016; 61(8):701-703; PMID:27053290; https://doi.org/10.1038/jhg.2016.32
  • Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo S-H, Danner T, Zhang M, Rainer PP, et al. Phosphodiesterase 9A controls nitric-oxide- independent cGMP and hypertrophic heart disease. Nature 2015; 519(7544):472-476; PMID:25799991; https://doi.org/10.1038/nature14332

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