Diagnostic and prognostic value of ABC transporter family member ABCG1 gene in clear cell renal cell carcinoma

References

• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Gupta K, Miller JD, Li JZ, et al. Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review. Cancer Treat Rev. 2008 May;34(3):193–205.
   PubMed Web of Science ®Google Scholar
• Escudier B, Porta C, Schmidinger M, et al. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2019 May 1;30(5):706–720.
   PubMed Web of Science ®Google Scholar
• Atkins MB, Tannir NM. Current and emerging therapies for first-line treatment of metastatic clear cell renal cell carcinoma. Cancer Treat Rev. 2018 Nov;70:127–137.
   PubMed Web of Science ®Google Scholar
• Motzer RJ, Bander NH, Nanus DM. Renal-cell carcinoma. N Engl J Med. 1996 Sep 19;335(12):865–875.
   PubMed Web of Science ®Google Scholar
• Lin W, Chen X, Chen T, et al. C1QTNF6 as a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma. DNA Cell Biol. 2020 Apr 13;39(6):1000–1011.
   Web of Science ®Google Scholar
• Zhao Y, Yan Y, Ma R, et al. Expression signature of six-snoRNA serves as novel non-invasive biomarker for diagnosis and prognosis prediction of renal clear cell carcinoma. J Cell Mol Med. 2020 Feb;24(3):2215–2228.
   PubMed Web of Science ®Google Scholar
• Xu D, Xu Y, Lv Y, et al. Identification of four pathological stage-relevant genes in association with progression and prognosis in clear cell renal cell carcinoma by integrated bioinformatics analysis. Biomed Res Int. 2020;2020:2137319.
   PubMed Web of Science ®Google Scholar
• Dean M, Hamon Y, Chimini G. The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res. 2001 Jul;42(7):1007–1017.
   PubMed Web of Science ®Google Scholar
• Vasiliou V, Vasiliou K, Nebert DW. Human ATP-binding cassette (ABC) transporter family. Hum Genomics. 2009 Apr 3;3(3):281–290.
   PubMedGoogle Scholar
• Lam F, Hussain S, Sinha J. An unusual cause of a limp in a child: developmental coxa vara. Emerg Med J. 2001 Jul;18(4):314.
   PubMed Web of Science ®Google Scholar
• Rudling M, Collins VP. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels are coordinately reduced in human renal cell carcinoma. Biochim Biophys Acta. 1996 Jan 5;1299(1):75–79.
   PubMedGoogle Scholar
• Dessi S, Batetta B, Pulisci D, et al. Cholesterol content in tumor tissues is inversely associated with high-density lipoprotein cholesterol in serum in patients with gastrointestinal cancer. Cancer. 1994 Jan 15;73(2):253–258.
   PubMed Web of Science ®Google Scholar
• Wu G, Wang Q, Xu Y, et al. Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist? Cell Death Dis. 2019 May 28;10(6):416.
   PubMedGoogle Scholar
• Hour TC, Kuo YZ, Liu GY, et al. Downregulation of ABCD1 in human renal cell carcinoma. Int J Biol Markers. 2009 Jul-Sep;24(3):171–178.
   PubMed Web of Science ®Google Scholar
• Yun EJ, Zhou J, Lin CJ, et al. The network of DAB2IP-miR-138 in regulating drug resistance of renal cell carcinoma associated with stem-like phenotypes. Oncotarget. 2017 Sep 15;8(40):66975–66986.
   PubMedGoogle Scholar
• Arai E, Sakamoto H, Ichikawa H, et al. Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome. Int J Cancer. 2014 Sep 15;135(6):1330–1342.
   PubMed Web of Science ®Google Scholar
• Reustle A, Fisel P, Renner O, et al. Characterization of the breast cancer resistance protein (BCRP/ABCG2) in clear cell renal cell carcinoma. Int J Cancer. 2018 Dec 15;143(12):3181–3193.
   PubMed Web of Science ®Google Scholar
• Li S, Yang J, Wang J, et al. Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1. Cell Biosci. 2018;8(1):9.
   PubMedGoogle Scholar
• Haenisch S, Zimmermann U, Dazert E, et al. Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex. Pharmacogenomics J. 2007 Feb 7;7(1):56–65.
   PubMed Web of Science ®Google Scholar
• Saleeb RM, Farag M, Lichner Z, et al. Modulating ATP binding cassette transporters in papillary renal cell carcinoma type 2 enhances its response to targeted molecular therapy. Mol Oncol. 2018 Oct;12(10):1673–1688.
   PubMed Web of Science ®Google Scholar
• Seliger B, Atkins D, Bock M, et al. Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation. Clin Cancer Res. 2003 May;9(5):1721–1727.
   PubMed Web of Science ®Google Scholar
• Kuo CY, Yoo TJ. In vitro inhibition of tritiated thymidine uptake in Morris hepatoma cells by normal rat liver extract: a possible liver chalone. J Natl Cancer Inst. 1977 Dec;59(6):1691–1695.
   PubMedGoogle Scholar
• Huang Y, Zhang Y, Jia L, et al. Circular RNA ABCB10 promotes tumor progression and correlates with pejorative prognosis in clear cell renal cell carcinoma. Int J Biol Markers. 2019 Jun;34(2):176–183.
   PubMed Web of Science ®Google Scholar
• D’Arcangelo D, Giampietri C, Muscio M, et al. WIPI1, BAG1, and PEX3 autophagy-related genes are relevant melanoma markers. Oxid Med Cell Longev. 2018;2018.
   Web of Science ®Google Scholar
• Chai AB, Ammit AJ, Gelissen IC. Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation. Respir Res. 2017 Feb 28;18(1):41.
   PubMedGoogle Scholar
• Zhu L, Tang F, Lei Z, et al. Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC-DLBCL cells. Mol Carcinog. 2019 Sep 26;58(12):2340–2352. .
   Web of Science ®Google Scholar
• Yvan-Charvet L, Wang N, Tall AR. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):139–143.
   PubMed Web of Science ®Google Scholar
• Sag D, Cekic C, Wu R, et al. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun. 2015 Feb 27;6(1):6354.
   PubMedGoogle Scholar
• Kober AC, Manavalan APC, Tam-Amersdorfer C, et al. Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jun;1862(6):573–588.
   PubMed Web of Science ®Google Scholar
• Vaughan AM, Oram JF. ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL. J Lipid Res. 2006 Nov;47(11):2433–2443.
   PubMed Web of Science ®Google Scholar
• Pereira CD, Martins F, Wiltfang J, et al. ABC transporters are key players in Alzheimer’s disease. J Alzheimers Dis. 2018;61(2):463–485.
   PubMed Web of Science ®Google Scholar
• Schumacher T, Benndorf RA, Transport ABC. Proteins in cardiovascular disease—a brief summary. Molecules. 2017 Apr 6;22(4):589.
   Web of Science ®Google Scholar
• Tarling EJ, De Aguiar Vallim TQ, Edwards PA. Role of ABC transporters in lipid transport and human disease. Trends Endocrinol Metab. 2013 Jul;24(7):342–350.
   PubMed Web of Science ®Google Scholar
• Harandi NM, Stavness I, Woo J. Subject-specific biomechanical modelling of the oropharynx: towards speech production. Comput Methods Biomech Biomed Eng Imaging Vis. 2017;5(6):416–426.
   PubMed Web of Science ®Google Scholar
• Liu X. ABC family transporters. Adv Exp Med Biol. 2019;1141:13–100.
   PubMed Web of Science ®Google Scholar
• Briz O, Perez-Silva L, Al-Abdulla R, et al. What “The Cancer Genome Atlas” database tells us about the role of ATP-binding cassette (ABC) proteins in chemoresistance to anticancer drugs. Expert Opin Drug Metab Toxicol. 2019 Jul;15(7):577–593.
   PubMed Web of Science ®Google Scholar
• Fletcher JI, Williams RT, Henderson MJ, et al. ABC transporters as mediators of drug resistance and contributors to cancer cell biology. Drug Resist Updat. 2016 May;26:1–9.
   PubMed Web of Science ®Google Scholar
• Tian C, Huang D, Yu Y, et al. ABCG1 as a potential oncogene in lung cancer. Exp Ther Med. 2017 Jun;13(6):3189–3194.
   PubMed Web of Science ®Google Scholar
• Wang Y, Liu H, Ready NE, et al. Genetic variants in ABCG1 are associated with survival of nonsmall-cell lung cancer patients. Int J Cancer. 2016 Jun 1;138(11):2592–2601.
   PubMed Web of Science ®Google Scholar
• Gonzalez HE, Gujrati M, Frederick M, et al. Identification of 9 genes differentially expressed in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2003 Jul;129(7):754–759.
   PubMedGoogle Scholar
• Demidenko R, Razanauskas D, Daniunaite K, et al. Frequent down-regulation of ABC transporter genes in prostate cancer. BMC Cancer. 2015 Oct 12;15(1):683.
   PubMedGoogle Scholar
• Jiang L, Zhao L, Bi J, et al. Glycolysis gene expression profilings screen for prognostic risk signature of hepatocellular carcinoma. Aging (Albany NY). 2019 Dec 2;11(23):10861–10882.
   PubMedGoogle Scholar
• Massari F, Ciccarese C, Santoni M, et al. Metabolic alterations in renal cell carcinoma. Cancer Treat Rev. 2015 Nov;41(9):767–776.
   PubMed Web of Science ®Google Scholar
• Drabkin HA, Gemmill RM. Cholesterol and the development of clear-cell renal carcinoma. Curr Opin Pharmacol. 2012 Dec;12(6):742–750.
   PubMed Web of Science ®Google Scholar
• Gebhard RL, Clayman RV, Prigge WF, et al. Abnormal cholesterol metabolism in renal clear cell carcinoma. J Lipid Res. 1987 Oct;28(10):1177–1184.
   PubMed Web of Science ®Google Scholar
• Kang HW, Seo SP, Kim WT, et al. Low preoperative serum cholesterol level is associated with aggressive pathologic features and poor cancer-specific survival in patients with surgically treated renal cell carcinoma. Int J Clin Oncol. 2018 Feb;23(1):142–150.
   PubMed Web of Science ®Google Scholar
• Lee H, Kim YJ, Hwang EC, et al. Preoperative cholesterol level as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with cyto-reductive nephrectomy. BMC Cancer. 2017 May 25;17(1):364.
   PubMedGoogle Scholar
• Peng D, He ZS, Li XS, et al. A novelpredictor of survival with renal cell carcinoma after nephrectomy. J Endourol. 2017 Apr;31(4):397–404.
   PubMed Web of Science ®Google Scholar
• Yang H, Li W, Lv Y, et al. Exploring the mechanism of clear cell renal cell carcinoma metastasis and key genes based on multi-tool joint analysis. Gene. 2019 Dec 15;720:144103.
   PubMed Web of Science ®Google Scholar
• Frambach S, De Haas R, Smeitink JAM, et al. Brothers in arms: ABCA1- and ABCG1-mediated cholesterol efflux as promising targets in cardiovascular disease treatment. Pharmacol Rev. 2020 Jan;72(1):152–190.
   PubMed Web of Science ®Google Scholar
• Ren K, Li H, Zhou HF, et al. Mangiferin promotes macrophage cholesterol efflux and protects against atherosclerosis by augmenting the expression of ABCA1 and ABCG1. Aging (Albany NY). 2019 Dec 2;11(23):10992–11009.
   PubMedGoogle Scholar
• Huesca-Gomez C, Torres-Paz YE, Martinez-Alvarado R, et al. Association between the transporters ABCA1/G1 and the expression of miR-33a/144 and the carotid intima media thickness in patients with arterial hypertension. Mol Biol Rep. 2020 Feb;47(2):1321–1329.
   PubMed Web of Science ®Google Scholar
• Koga M, Kanaoka Y, Okamoto M, et al. Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression. J Pharmacol Sci. 2020 Jan;142(1):9–15.
   PubMed Web of Science ®Google Scholar
• Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006 Jan 15;66(2):605–612.
   PubMed Web of Science ®Google Scholar
• Movahedi K, Laoui D, Gysemans C, et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res. 2010 Jul 15;70(14):5728–5739.
   PubMed Web of Science ®Google Scholar
• Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 2004 Jan 4;4(1):71–78.
   PubMed Web of Science ®Google Scholar
• Lin EY, Li JF, Gnatovskiy L, et al. Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res. 2006 Dec 1;66(23):11238–11246.
   PubMed Web of Science ®Google Scholar
• Sica A, Larghi P, Mancino A, et al. Macrophage polarization in tumour progression. Semin Cancer Biol. 2008 Oct;18(5):349–355.
   PubMed Web of Science ®Google Scholar
• Hiraoka K, Zenmyo M, Watari K, et al. Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages. Cancer Sci. 2008 Aug;99(8):1595–1602.
   PubMed Web of Science ®Google Scholar
• Li Y, Schwabe RF, DeVries-Seimon T, et al. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. J Biol Chem. 2005 Jun 10;280(23):21763–21772.
   PubMed Web of Science ®Google Scholar
• Solinas G, Germano G, Mantovani A, et al. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol. 2009 Nov;86(5):1065–1073.
   PubMed Web of Science ®Google Scholar
• Wei H, Tarling EJ, McMillen TS, et al. ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and ratio of M1 to M2 cells in obesity and caloric restriction. J Lipid Res. 2015 Dec;56(12):2337–2347.
   PubMed Web of Science ®Google Scholar
• Buczek M, Escudier B, Bartnik E, et al. Resistance to tyrosine kinase inhibitors in clear cell renal cell carcinoma: from the patient’s bed to molecular mechanisms. Biochim Biophys Acta. 2014 Jan;1845(1):31–41.
   PubMed Web of Science ®Google Scholar
• Van Der Mijn JC, Mier JW, Broxterman HJ, et al. Predictive biomarkers in renal cell cancer: insights in drug resistance mechanisms. Drug Resist Updat. 2014 Oct-Dec;17(4–6):77–88.
   PubMed Web of Science ®Google Scholar
• Randall JM, Millard F, Kurzrock R. Molecular aberrations, targeted therapy, and renal cell carcinoma: current state-of-the-art. Cancer Metastasis Rev. 2014 Dec;33(4):1109–1124.
   PubMed Web of Science ®Google Scholar
• Garcia-Donas J, Rodriguez-Moreno JF, Romero-Laorden N, et al. Renal carcinoma pharmacogenomics and predictors of response: steps toward treatment individualization. Urol Oncol. 2015 Apr;33(4):179–186.
   PubMed Web of Science ®Google Scholar
• Yvan-Charvet L, Welch C, Pagler TA, et al. Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation. 2008 Oct 28;118(18):1837–1847.
   PubMed Web of Science ®Google Scholar
• Hein MY, Hubner NC, Poser I, et al. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712–723.
   PubMed Web of Science ®Google Scholar
• Abdelmohsen K, Srikantan S, Yang X, et al. Ubiquitin-mediated proteolysis of HuR by heat shock. Embo J. 2009 May 6;28(9):1271–1282.
   PubMed Web of Science ®Google Scholar
• Fei T, Chen Y, Xiao T, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5207–E5215.
   PubMed Web of Science ®Google Scholar
• Na CH, Jones DR, Yang Y, et al. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J Proteome Res. 2012 Sep 7;11(9):4722–4732.
   PubMed Web of Science ®Google Scholar