365
Views
18
CrossRef citations to date
0
Altmetric
Articles

Predominant role of antioxidants in ameliorating the oxidative stress induced by pesticides

, &

References

  • Sachin K, Sharma AK, Rawat SS, et al. Use of pesticides in agriculture and livestock animals and its impact on environment of India. Asian J Environ Sci. 2013;8:51–57.
  • Sitaramaraju S, Prasad N, Reddy VC, et al. Impact of pesticides used for crop production on the environment. J Chem Pharmaceutical Sci. 2014;3:75–79.
  • Sharma A, Kumar V, Shahzad B, et al. Worldwide pesticide usage and its impacts on ecosystem. Springer Nature Appl Sci. 2019;1:1446.
  • Damalas CA, Eleftherohorinos IG. Pesticide exposure, safety issues, and risk assessment indicators. IJERPH. 2011;8(5):1402–1419. doi:10.3390/ijerph8051402.
  • Mostafalou S, Abdollahi M. Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives. Toxicol Appl Pharmacol. 2013;268(2):157–177. doi:10.1016/j.taap.2013.01.025.
  • Runkle J, Flocks J, Economos J, et al. Occupational risks and pregnancy and infant health outcomes in Florida farmworkers. IJERPH. 2014;11(8):7820–7840. doi:10.3390/ijerph110807820.
  • Mishra K, Sharma RC. Assessment of organochlorine pesticides in human milk and risk exposure to infants from North-East India. Sci Total Environ. 2011;409(23):4939–4949. doi:10.1016/j.scitotenv.2011.07.038.
  • Rose M, Fernandes A, Mortimer D, et al. Contamination of fish in UK fresh water systems: risk assessment for human consumption. Chemosphere. 2015;122:183–189. doi:10.1016/j.chemosphere.2014.11.046.
  • Hernandez AF, Parron T, Tsatsakis AM, et al. Toxic effects of pesticide mixtures at a molecular level: Their relevance to human health. Toxicology. 2013;307:136–145. doi:10.1016/j.tox.2012.06.009.
  • Xavier R Rekha K, Bairy KL. Health perspective of pesticide exposure and dietary management. Mal J Nutr. 2004;10(1):39–51.
  • Ia A-S. Pesticides: a review article. J Environ Pathol Toxicol Oncol. 1994;13:151–161.
  • Bolognesi C, Morasso G. Genotoxicity of pesticides: potential risk for consumers. Trends Food Sci Technol. 2000;11(4–5):182–187. doi:10.1016/S0924-2244(00)00060-1.
  • Saleem U, Ejaz S, Ashraf M, et al. Mutagenic and cytotoxic potential of Endosulfan and Lambda-cyhalothrin — In vitro study describing individual and combined effects of pesticides. J Environ Sci. 2014;26(7):1471–1479. doi:10.1016/j.jes.2014.05.013.
  • Abdollahi M, Ranjbar A, Shadnia S, et al. Pesticides and oxidative stress: a review. Med. Sci. Monit. 2004;10(6):RA141–147.
  • Hussain AL. Role of oxidative stress in organophosphate insecticide toxicity – Short review. Pestic Biochem Physiol. 2010;98:145–150.
  • Kisby GE, Muniz JF, Scherer J, et al. Oxidative stress and DNA damage in agricultural workers. J Agromed. 2009;14(2):206–214. doi:10.1080/10599240902824042.
  • Abass K, Turpeinen M, Rautio A, et al. Metabolism of pesticides by human Cytochrome P450 Enzymes. In: Perveen F, ed. Vitro – A Survey, Insecticides - Advances in Integrated Pest Management. Finland: InTech; 2012. doi:10.5772/28088.
  • Hennig B, Hammock BD, Slim R, et al. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. Int J Hyg Environ Health. 2002;205(1–2):95–102. doi:10.1078/1438-4639-00134.
  • Hrycay EG, Bandiera SM. Involvement of Cytochrome P450 in reactive oxygen species formation and cancer. Adv Pharmacol. 2015;74:35–84. doi:10.1016/bs.apha.2015.03.003.
  • Dostalek M, Hardy KD, Milne G, et al. Development of Oxidative Stress by Cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems. J Biol Chem. 2008;283(25):17147–17157. doi:10.1074/jbc.M802447200.
  • Mecdad AA, Ahmed MH, ElHalwagy MEA, et al. A study on oxidative stress biomarkers and immunomodulatory effects of pesticides in pesticide-sprayers. Egyptian J Forensic Sci. 2011;1(2):93–98. doi:10.1016/j.ejfs.2011.04.012.
  • Alavanja MCR, Ross MK, Bonner MR. Increased cancer burden among pesticide applicators and others due to pesticide exposure. CA. 2013;63(2):120–142. doi:10.3322/caac.21170.
  • Bhattacharyya A, Chattopadhyay R, Mitra S, et al. Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. Physiol Rev. 2014;94(2):329–354. doi:10.1152/physrev.00040.2012.
  • Sharma P, Jha AB, Dubey RS, et al. Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. J Botany. 2012;2012:1–26. doi:10.1155/2012/217037.
  • Al-Dalaen SM, Al QA. Review article: Oxidative stress versus antioxidants. BIO. 2014;2(5):60–71. doi:10.11648/j.bio.20140205.11.
  • Bendich A, Machlin LJ, Scandurra O, et al. The antioxidant role of vitamin C. Adv Free Radical Biol Med. 1986;2(2):419–444. doi:10.1016/S8755-9668(86)80021-7.
  • Altuntas I, Delibas N, Demirci M, et al. The effects of methidathion on lipid peroxidation and some liver enzymes role of vitamins E and C. Arch Toxicol. 2002;76(8):470–473. doi:10.1007/s00204-002-0359-1.
  • Serbecic N, Beutelspacher SC. Anti-oxidative vitamins prevent lipid-peroxidation and apoptosis in corneal endothelial cells. Cell Tissue Res. 2005;320(3):465–475. doi:10.1007/s00441-004-1030-3.
  • Ambali S, Akanbi D, Igbokwe N, et al. Evaluation of Subchronic Chlorpyrifos poisoning on haematological and serum biochemical changes in mice and protective effect of vitamin C. J Toxicol Sci. 2007;32(2):111–120. doi:10.2131/jts.32.111.
  • Frei B, Stocker R, England L, et al. Acorbate: The most effective antioxidant in human blood plasma. Adv Ex Med Biol. 1990;264:155–163.
  • Halliwell B. Vitamin C: Antioxidant or Prooxidant in vivo? Free Radical Res. 1996;25(5):439–454. doi:10.3109/10715769609149066.
  • Grajeda-Cota P, VinicioRamı́rez-Mares M, González de Mejı́a E. Vitamin C protects against in vitro cytotoxicity of cypermethrin in rat hepatocytes. Toxicol in Vitro. 2004;18(1):13–19. doi:10.1016/S0887-2333(03)00077-8.
  • Fetoui H, Garoui EM, Makni-Ayadi F, et al. Oxidative stress induced by lambda-cyhalothrin (LTC) in rat erythrocytes and brain: Attenuation by vitamin C. Environ Toxicol Pharmacol. 2008;26(2):225–231. doi:10.1016/j.etap.2008.04.002.
  • Fetoui H, Garoui EM, Zeghal N. Lambda-cyhalothrin-induced biochemical and histopathological changes in the liver of rats: Ameliorative effect of ascorbic acid. Exp Toxicol Pathol. 2009;61(3):189–196. doi:10.1016/j.etp.2008.08.002.
  • Fetoui H, Makni M, Garoui EM, et al. Toxic effects of lambda-cyhalothrin, a synthetic pyrethroid pesticide, on the rat kidney: Involvement of oxidative stress and protective role of ascorbic acid. Exp Toxicol Pathol. 2010;62(6):593–599. doi:10.1016/j.etp.2009.08.004.
  • Rai DK, Rai PK, Rizvi SI, et al. Carbofuran - induced toxicity in rats: Protective role of vitamin C. Exp Toxicol Pathol. 2009;61(6):531–535. doi:10.1016/j.etp.2008.11.003.
  • Jaiswal SK, Siddiqi NJ, Sharma B. Carbofuran induced oxidative stress in rat heart: Ameliorative effect of Vitamin C. ISRN Oxidative Med. 2013;2013:1–10. doi:10.1155/2013/824102.
  • EL-Gendy KS, Aly NM, Mahmoud FH, et al. The role of vitamin C as antioxidant in protection of oxidative stress induced by imidacloprid. Food Chem Toxicol. 2010;48(1):215–221. doi:10.1016/j.fct.2009.10.003.
  • Reddy A, Soujanya S, Lakshman M, Kumar A. Evaluation of the protective role of vitamin C in Imidacloprid-induced hepatotoxicity in male Albino rats. J Nat Sc Biol Med. 2013;4(1):63–67. doi:10.4103/0976-9668.107262.
  • Aly N, EL-Gendy K, Mahmoud F, El-Sebae AK. Protective effect of vitamin C against chlorpyrifos oxidative stress in male mice. Pestic Biochem Physiol. 2010;97(1):7–12. doi:10.1016/j.pestbp.2009.11.007.
  • Yavuz T, Delibas N, Yildirim B, et al. Vascular wall damage in rats induced by methidathion and ameliorating effect of vitamins E and C. Arch Toxicol. 2004;78(11):655–659. doi:10.1007/s00204-004-0593-9.
  • Ando M, Yoshioka T, Akiyama J, et al. Regulation of neutrophil superoxide generation by alpha-tocopherol in human peripheral umbilical-cord blood. J Obstet Gynaecol Res. 1996;22(5):507–516. doi:10.1111/j.1447-0756.1996.tb01064.x.
  • Burton GW, Joyce A, Ingold KU. Is vitamin E the only lipid soluble, chain breaking antioxidant in human blood plasma and erythrocyte membrane. Arch Biochem Biophys. 1983;221(1):281–290. doi:10.1016/0003-9861(83)90145-5.
  • Giray B, Gürbay A, Hincal F. Cypermethrin-induced oxidative stress in rat brain and liver is prevented by Vitamin E or allopurinol. Toxicol Lett. 2001;118(3):139–146. doi:10.1016/S0378-4274(00)00277-0.
  • Yousef MI, Awad TI, Mohamed EH. Deltamethrin-induced oxidative damage and biochemical alterations in rat and its attenuation by Vitamin E. Toxicology. 2006;227(3):240–247. doi:10.1016/j.tox.2006.08.008.
  • Ozden S, Catalgol B, Gezginci-Oktayoglu S, et al. Methiocarb-induced oxidative damage following sub-acute exposure and the protective effects of vitamin E and taurine in rats. Food Chem Toxicol. 2009;47(7):1676–1684. doi:10.1016/j.fct.2009.04.018.
  • Singh M, Sandhir R, Kiran R. Effects on antioxidant status of liver following Atrazine exposure and its attenuation by vitamin E. Exp Toxicol Pathol. 2011;63(3):269–276. doi:10.1016/j.etp.2010.01.005.
  • Sargazi Z, Reza NM, Mehdi J, et al. Diazinon-induced ovarian toxicity and protection by vitamins E. Iranian J Toxicol. 2014;8:1130–1135.
  • Suntres ZE. Role of antioxidants in paraquat toxicity. Toxicology. 2002;180(1):65–77. doi:10.1016/S0300-483X(02)00382-7.
  • Kumar SJ, Banudevi S, Sharmila M, et al. Effects of Vitamin C and Vitamin E on PCB (Aroclor 1254) induced oxidative stress, androgen binding protein and lactate in rat Sertoli cells. Reprod Toxicol. 2004;19(2):201–208. doi:10.1016/j.reprotox.2004.08.001.
  • Akturk O, Demirin H, Sutcu R, Yilmaz N, Koylu H, Altuntas I. The effects of diazinon on lipid peroxidation and antioxidant enzymes in rat heart and ameliorating role of vitamin E and vitamin C. Cell Biol Toxicol. 2006;22(6):455–461. doi:10.1007/s10565-006-0138-5.
  • Yu F, Wang Z, Ju B, Wang Y, Wang J, Bai D. Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E. Exp Toxicol Pathol. 2008;59(6):415–423. doi:10.1016/j.etp.2007.11.007.
  • Ahmed NS, Mohamed AS, Abdel-Wahhab MA. Chlorpyrifos-induced oxidative stress and histological changes in retinas and kidney in rats: Protective role of ascorbic acid and alpha tocopherol. Pestic Biochem Physiol. 2010;98(1):33–38. doi:10.1016/j.pestbp.2010.04.006.
  • Yahya AS, Mohamed AA, Gamal EH. Dimethoate-induced oxidative stress and morphological changes in the liver of guinea pig and the protective effect of vitamin C and E. Asian J Biol Sci. 2012;5:9–19.
  • Abdallah BF, Fetoui H, Zribi N, et al. Antioxidant supplementations in vitro improve rat sperm parameters and enhance antioxidant enzyme activities against dimethoate-induced sperm damages. Andrologia. 2012;44(Suppl. 1):272–279. doi:10.1111/j.1439-0272.2011.01177.x.
  • El-Demerdash FM. Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. Toxicol in Vitro. 2007;21(3):392–397. doi:10.1016/j.tiv.2006.09.019.
  • Zervos IA, Nikolaidis E, Lavrentiadou SN, et al. Endosulfan-induced lipid peroxidation in rat brain and its effect on t-PA and PAI-1: ameliorating effect of vitamins C and E. J Toxicol Sci. 2011;36(4):423–433. doi:10.2131/jts.36.423.
  • Heydari Y, Hossein KJ, Saberi R, et al. Effect of vitamins E and C on sexual cell lineages in adult male rats under oxidative stress arising from the use of endosulfan. Adv Environ Biol. 2013;7:4714–4718.
  • Heydari Y, Hosseini SH, Keshavarz M, et al. Evaluating the effect of vitamins E and C on sexual cell lineages in adult male rats under oxidative stress induced by endosulfan consumption. J Fasa Univ Med Sci. 2014;4:250–257.
  • Badgujar PC, Pawar NN, Chandratre GA, et al. Fipronil induced oxidative stress in kidney and brain of mice: Protective effect of vitamin E and vitamin C. Pestic Biochem Physiol. 2015;118:10–18. doi:10.1016/j.pestbp.2014.10.013.
  • Badgujar PC, Chandratre GA, Pawar NN, et al. Fipronil induced oxidative stress involves alterations in SOD1 and catalase gene expression in male mice liver: Protection by vitamins E and C. Environ Toxicol. 2016;31(9):1147–1158. doi:10.1002/tox.22125.
  • Verma RS, Mehta A, Srivastava N. In vivo chlorpyrifos induced oxidative stress: Attenuation by antioxidant vitamins. Pestic Biochem Physiol. 2007;88(2):191–196. doi:10.1016/j.pestbp.2006.11.002.
  • Verma RS, Mehta A, Srivastava N. Comparative studies on chlorpyrifos and methyl parathion induced oxidative stress in different parts of rat brain: Attenuation by antioxidant vitamin. Pestic Biochem Physiol. 2009;95(3):152–158. doi:10.1016/j.pestbp.2009.08.004.
  • Patil JA, Patil AJ, Govindwar SP, et al. Protection of liver injury by vitamin C, E and GSH after methomyl toxicity in rat. J Pharmaceutical, Chem Biol Sci. 2016;3:506–517.
  • Goel A, Dani V, Dhawan DK. Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity. Chem Biol Interact. 2005;156(2–3):131–140. doi:10.1016/j.cbi.2005.08.004.
  • Mansour SA, Mossa AH. Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc. Pestic Biochem Physiol. 2009;93(1):34–39. doi:10.1016/j.pestbp.2008.09.004.
  • Mansour SA, Mossa AH. Oxidative damage, biochemical and histopathological alterations in rats exposed to chlorpyrifos and the antioxidant role of zinc. Pestic Biochem Physiol. 2010;96(1):14–23. doi:10.1016/j.pestbp.2009.08.008.
  • Alvarez JG, Storey BT. Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation. Gamete Res. 1989;23(1):77–90. doi:10.1002/mrd.1120230108.
  • Rotruck JT, Pope AL, Ganther HE, et al. Selenium: biochemical role as a component of glutathione peroxidase. Science. 1973;179(4073):588–590. doi:10.1126/science.179.4073.588.
  • Adesiyan AC, Oyejola TO, Abarikwu SO, et al. Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity. Exp Toxicol Pathol. 2011;63(3):201–207. doi:10.1016/j.etp.2009.11.008.
  • Amara BI, Soudani N, Hakim A, et al. Dimethoate-induced oxidative damage in erythrocytes of female adult rats: possible protective effect of vitamin E and selenium supplemented to diet. Toxicol Ind Health. 2012;28(3):222–237. doi:10.1177/0748233711410909.
  • Amara BI, Soudani N, Troudi A, et al. Dimethoate induced oxidative damage and histopathological changes in lung of adult rats: Modulatory effects of Selenium and/or Vitamin E. Biomed Environ Sci. 2012;25(3):340–351. doi:10.3967/0895-3988.2012.03.013.
  • Amara BI, Soudani N, Hakim A, et al. Protective effects of vitamin E and selenium against dimethoate-induced cardiotoxicity in vivo: Biochemical and histological studies. Environ Toxicol. 2013;28(11):630–643. doi:10.1002/tox.20759.
  • Yurumez Y, Cemek M, Yavuz Y, et al. Beneficial Effect of N-Acetylcysteine against organophosphate toxicity in mice. Biol Pharm Bull. 2007;30(3):490–494. doi:10.1248/bpb.30.490.
  • Dorval J, Hontela A. Role of glutathione redox cycle and catalase in defense against oxidative stress induced by endosulfan in adrenocortical cells of rainbow trout (Oncorhynchus mykiss). Toxicol Appl Pharmacol. 2003;192(2):191–200. doi:10.1016/S0041-008X(03)00281-3.
  • Llopis SP, Ferrando MD, Pena JB. Fish tolerance to organophosphate-induced oxidative stress is dependent on the glutathione metabolism and enhanced by N-acetylcysteine. Aquat Toxicol. 2003;65(4):337–360. doi:10.1016/S0166-445X(03)00148-6.
  • Cankayali L, Demirag K, Eris O, et al. The effects of N-acetylcysteine on oxidative stress in organophosphate poisoning model. Adv Therapy. 2005;22(2):107–116. doi:10.1007/BF02849882.
  • Shadnia S, Dasgar M, Taghikhani S, et al. Protective Effects of α-Tocopherol and N-Acetyl-Cysteine on diazinon-induced oxidative stress and acetylcholinesterase inhibition in rats. Toxicol Mech Methods. 2007;17(2):109–115. doi:10.1080/15376510600860318.
  • Sevgiler Y, Piner P, Durmaz H, et al. Effects of N-acetylcysteine on oxidative responses in the liver of fenthion exposed Cyprinus carpio. Pestic Biochem Physiol. 2007;87(3):248–254. doi:10.1016/j.pestbp.2006.08.003.
  • Ahmad I, Shukla S, Kumar A, et al. Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb- and paraquat-induced hepatotoxicity in rats. Chem Biol Interact. 2013;201(1–3):9–18. doi:10.1016/j.cbi.2012.10.027.
  • Astiz M, de Alaniz MJ, Marra CA. The oxidative damage and inflammation caused by pesticides are reverted by lipoic acid in rat brain. Neurochem Int. 2012;61(7):1231–1241. doi:10.1016/j.neuint.2012.09.003.
  • Elsawy H, Al-Omair MA, Sedky A, et al. Protective effect of α-lipoic acid against α-cypermethrin-induced changes in rat cerebellum. J Chem Neuroanat. 2017;86:52–58. doi:10.1016/j.jchemneu.2017.08.005.
  • Ahmed T, Pathak R, Mustafa MD, et al. Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells. Environ Monit Assess. 2011;179(1–4):293–299. doi:10.1007/s10661-010-1736-5.
  • Patil JA, Patil AJ, Sontakke AV, et al. Effect of Vitamin E supplementation on biochemical parameters in pesticides sprayers of grape gardens of Western Maharashtra (India). Ind J Clin Biochem. 2012;27(2):134–140. doi:10.1007/s12291-012-0207-x.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.