Chemical contaminant exposures assessed using silicone wristbands among fuel station attendants, taxi drivers and commercial motorcycle riders in Kampala, Uganda

References

• World Health Organization. WHO Global Ambient Air Quality Database (Update 2018). Geneva, Switzerland: World Health Organization; 2018.
   Google Scholar
• Samoli E, Atkinson RW, Analitis A, et al. Associations of short-term exposure to traffic-related air pollution with cardiovascular and respiratory hospital admissions in London, UK. Occup Environ Med. 2016;73(5):300–307. doi:10.1136/oemed-2015-103136.
   PubMed Web of Science ®Google Scholar
• McDonald BC, de Gouw JA, Gilman JB, et al. Volatile chemical products emerging as largest petrochemical source of urban organic emissions. Science. 2018;359(6377):760–764. doi:10.1126/science.aaq0524.
   PubMed Web of Science ®Google Scholar
• S E. Air Quality Monitoring using Beta Attenuation Monitor 1022 and E-Samplers in Kampala Uganda: status of air quality Oct 2017-Sept 2019., Preliminary results from the Eastern Africa GEOHealth Hub. Environmental Epidemiology. 2019;3:114. doi:10.1097/01.EE9.0000606972.97552.56.
   Google Scholar
• Kirenga BJ, Meng Q, van Gemert F, et al. The state of ambient air quality in two ugandan cities: a pilot cross-sectional spatial assessment. Int J Environ Res Public Health. 2015;12(7):8075–8091. doi:10.3390/ijerph120708075.
   PubMed Web of Science ®Google Scholar
• Atuyambe L, et al. Situation analysis and needs assessment for Uganda: air pollution, occupational safety and health, and climate change. Makerere University School of Public Health (MakSPH) Uganda and University of Southern California (USC) USA. 2015.
   Google Scholar
• Jovanelly TJ, et al. Comparative assessment of ambient air standards in rural areas to uganda city centers. J Public Health Develop Count. 2017;3(1):371–380.
   Google Scholar
• Johnson O, Umoren Q. Assessment of occupational hazards, health problems and safety practices of petrol station attendants in Uyo, Nigeria. J Commun Med Prim Health Care. 2018;30(1):47–57.
   Google Scholar
• Mutungi J, Moturi W, Makindi S. Occupational safety and health management systems and their compliance among petrol stations in Kenya: A case study in Nakuru county. CJAST. 2019;1–8. doi:10.9734/cjast/2019/v37i230275.
   Google Scholar
• Paulik LB, Anderson KA. Considerations for measuring exposure to chemical mixtures. In: Rider CV and Simmons JE, eds. Chemical Mixtures and Combined Chemical and Nonchemical Stressors: Exposure, Toxicity, Analysis, and Risk. Cham: Springer International Publishing; 2018:37–80.
   Google Scholar
• Clausen AS, Jørs E, Atuhaire A, et al. Effect of integrated pest management training on ugandan small-scale farmers. Environ Health Insights. 2017;11:1178630217703391. doi:10.1177/1178630217703391.
   Google Scholar
• Prüss-Ustün A, et al. Preventing disease through healthy environments, a global assessment of the burden of disease from environmental risks; 2016.
   Google Scholar
• Espina C, Straif K, Friis S, et al. European code against cancer 4th edition: environment, occupation and cancer. Cancer Epidemiol. 2015;39(Suppl. 1):S84–S92. doi:10.1016/j.canep.2015.03.017.
   PubMedGoogle Scholar
• Loomis D, Grosse Y, Lauby-Secretan B, et al. The carcinogenicity of outdoor air pollution. Lancet Oncol. 2013;14(13):1262–1263. doi:10.1016/s1470-2045(13)70487-x.
   PubMed Web of Science ®Google Scholar
• Forman MR, Winn DM, Collman GW, et al. Environmental exposures, breast development and cancer risk: through the looking glass of breast cancer prevention. Reprod Toxicol. 2015;54:6–10. doi:10.1016/j.reprotox.2014.10.019.
   PubMed Web of Science ®Google Scholar
• Engel LS, Werder E, Satagopan J, et al. Insecticide use and breast cancer risk among farmers’ wives in the agricultural health study. Environ Health Perspect. 2017;125(9):097002. doi:10.1289/EHP1295.
   PubMed Web of Science ®Google Scholar
• García-Pérez J, Lope V, Pérez-Gómez B, et al. Risk of breast cancer and residential proximity to industrial installations: new findings from a multicase-control study (MCC-Spain). Environ Pollut. 2018;237:559–568. doi:10.1016/j.envpol.2018.02.065.
   PubMed Web of Science ®Google Scholar
• Philippat C, Bennett D, Calafat AM, et al. Exposure to select phthalates and phenols through use of personal care products among Californian adults and their children. Environ Res. 2015;140:369–376. doi:10.1016/j.envres.2015.04.009.
   PubMed Web of Science ®Google Scholar
• Hammel SC, Hoffman K, Webster TF, et al. Measuring personal exposure to organophosphate flame retardants using silicone wristbands and hand wipes. Environ Sci Technol. 2016;50(8):4483–4491. doi:10.1021/acs.est.6b00030.
   PubMed Web of Science ®Google Scholar
• Taylor KW, Troester MA, Herring AH, et al. Associations between personal care product use patterns and breast cancer risk among white and black women in the sister study. Environ Health Perspect. 2018;126(2):027011. doi:10.1289/EHP1480.
   PubMed Web of Science ®Google Scholar
• Scheel JR, Nealey EM, Orem J, et al. ACR BI-RADS use in low-income countries: an analysis of diagnostic breast ultrasound practice in Uganda. J Am Coll Radiol. 2016;13(2):163–169. doi:10.1016/j.jacr.2015.07.035.
   PubMed Web of Science ®Google Scholar
• Zuwasti U, Abbey G, Pollack E, et al. Breast imaging in global health: serving the underserved. Curr Radiol Rep. 2020;8(5):5. doi:10.1007/s40134-020-00349-z.
   Google Scholar
• Yaqub G, et al. Biomonitoring of workers exposed to volatile organic compounds associated with different occupations by headspace GC-FID. J Chem. 2020;2020;6956402.
   Web of Science ®Google Scholar
• Singh A, Bodakhe SH. Resveratrol delay the cataract formation against naphthalene‐induced experimental cataract in the albino rats. J Biochem Mol Toxicol. 2020;34(1):e22420. doi:10.1002/jbt.22420.
   PubMed Web of Science ®Google Scholar
• Prager JC. Environmental contaminant reference databook. 1995.
   Google Scholar
• Singh S, Singh J. Dermal toxicity and microscopic alterations by JP-8 jet fuel components in vivo in rabbit. Environ Toxicol Pharmacol. 2004;16(3):153–161. doi:10.1016/j.etap.2003.12.001.
   PubMed Web of Science ®Google Scholar
• Dishaw LV, Powers CM, Ryde IT, et al. Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. Toxicol Appl Pharmacol. 2011;256(3):281–289. doi:10.1016/j.taap.2011.01.005.
   PubMed Web of Science ®Google Scholar
• Meeker JD, Cooper EM, Stapleton HM, et al. Exploratory analysis of urinary metabolites of phosphorus-containing flame retardants in relation to markers of male reproductive health. Endocr Disruptors (Austin). 2013;1(1):e26306. doi:10.4161/endo.26306.
   PubMedGoogle Scholar
• McGee SP, Konstantinov A, Stapleton HM, et al. Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor. Toxicol Sci. 2013;133(1):144–156. doi:10.1093/toxsci/kft020.
   PubMed Web of Science ®Google Scholar
• Bollati V, Baccarelli A. Environmental epigenetics. Heredity (Edinb). 2010;105(1):105–112. doi:10.1038/hdy.2010.2.
   PubMed Web of Science ®Google Scholar
• Preuss R, Angerer J, Drexler H. Naphthalene—an environmental and occupational toxicant. Int Arch Occup Environ Health. 2003;76(8):556–576. doi:10.1007/s00420-003-0458-1.
   PubMed Web of Science ®Google Scholar
• Santucci K, Shah B. Association of naphthalene with acute hemolytic anemia. Acad Emerg Med. 2000;7(1):42–47. doi:10.1111/j.1553-2712.2000.tb01889.x.
   PubMed Web of Science ®Google Scholar
• Uthuman A, Jayasinghe C, Fernando A. Acute intravascular hemolysis due to naphthalene toxicity: a case report. J Med Case Rep. 2019;13(1):91. doi:10.1186/s13256-018-1963-x.
   PubMedGoogle Scholar
• Slaga T, Triplett L, Nesnow S. Mutagenic and carcinogenic potency of extracts of diesel and related environmental emissions: two-stage carcinogenesis in skin tumor sensitive mice (SENCAR). Environ Int. 1981;5(4-6):417–423. doi:10.1016/0160-4120(81)90092-1.
   Google Scholar
• Schupp T, Bolt HM, Jaeckh R, Hengstler JG. Benzene and its methyl-derivatives: derivation of maximum exposure levels in automobiles. Toxicol Lett. 2006;160(2):93–104. doi:10.1016/j.toxlet.2005.06.012.
   PubMed Web of Science ®Google Scholar
• Janik-Spiechowicz E, Wyszyńska K, Dziubałtowska E. Genotoxicity evaluation of trimethylbenzenes. Mutat Res. 1998;412(3):299–305. doi:10.1016/s1383-5718(97)00202-7.
   PubMed Web of Science ®Google Scholar
• Fuente A, McPherson B, Cardemil F. Xylene-induced auditory dysfunction in humans. Ear Hear. 2013;34(5):651–660. doi:10.1097/AUD.0b013e31828d27d7.
   PubMed Web of Science ®Google Scholar
• Sułkowski WJ. Effects of occupational exposure to a mixture of solvents on the inner ear: a field study. Int J Occup Med Environ Health. 2002;15(3):247–256.
   PubMedGoogle Scholar
• Kandyala R, Raghavendra SPC, Rajasekharan ST. Xylene: An overview of its health hazards and preventive measures. J Oral Maxillofac Pathol. 2010;14(1):1–5. doi:10.4103/0973-029X.64299.
   PubMedGoogle Scholar
• Rappaport SM. Implications of the exposome for exposure science. J Expo Sci Environ Epidemiol. 2011;21(1):5–9. doi:10.1038/jes.2010.50.
   PubMed Web of Science ®Google Scholar
• Anderson KA, Points GL, Donald CE, et al. Preparation and performance features of wristband samplers and considerations for chemical exposure assessment. J Expo Sci Environ Epidemiol. 2017;27(6):551–559. doi:10.1038/jes.2017.9.
   PubMed Web of Science ®Google Scholar
• O'Connell SG, Kincl LD, Anderson KA. Silicone wristbands as personal passive samplers. Environ Sci Technol. 2014;48(6):3327–3335. doi:10.1021/es405022f.
   PubMed Web of Science ®Google Scholar
• Kerebba N, Ssebugere P, Kwetegyeka J, et al. Concentrations and sources apportionment of polycyclic aromatic hydrocarbons in sediments from the Uganda side of Lake Victoria. Environ Sci Process Impacts. 2017;19(4):570–577. doi:10.1039/c7em00017k.
   PubMed Web of Science ®Google Scholar
• Ofori SA, Cobbina SJ, Doke DA. The occurrence and levels of polycyclic aromatic hydrocarbons (PAHs) in African environments—a systematic review. Environ Sci Pollut Res Int. 2020;27(26):32389–32431. doi:10.1007/s11356-020-09428-2.
   PubMed Web of Science ®Google Scholar
• Munyeza CF, Rohwer ER, Forbes PBC. A review of monitoring of airborne polycyclic aromatic hydrocarbons: An African perspective. Trends Environ Anal Chem. 2019;24:e00070. doi:10.1016/j.teac.2019.e00070.
   Web of Science ®Google Scholar
• Wild CP. The exposome: from concept to utility. Int J Epidemiol. 2012;41(1):24–32. doi:10.1093/ije/dyr236.
   PubMed Web of Science ®Google Scholar
• UBOS-Uganda. Leveraging Uganda’s Population Dynamics for a Resilient Future amidst COVID-19. Highlighting Population Issues through Statistics. Uganda Bureau of Statistics (UBOS). 2020; Kampala-Uganda.
   Google Scholar
• Citypopulation. The population of the regions of Uganda according to census results and latest official estimates. 2016. http://citypopulation.de/Uganda-Cities.html. Accessed April 24, 2018.
   Google Scholar
• UBOS. National population and housing census, 20114. 2015.
   Google Scholar
• Dixon HM, Scott RP, Holmes D, et al. Silicone wristbands compared with traditional polycyclic aromatic hydrocarbon exposure assessment methods. Anal Bioanal Chem. 2018;410(13):3059–3071. doi:10.1007/s00216-018-0992-z.
   PubMed Web of Science ®Google Scholar
• Donald CE, Scott RP, Blaustein KL, et al. Silicone wristbands detect individuals’ pesticide exposures in West Africa. R Soc Open Sci. 2016;3(8):160433. doi:10.1098/rsos.160433.
   PubMed Web of Science ®Google Scholar
• Bergmann AJ, North PE, Vasquez L, et al. Multi-class chemical exposure in rural Peru using silicone wristbands. J Expo Sci Environ Epidemiol. 2017;27(6):560–568. doi:10.1038/jes.2017.12.
   PubMed Web of Science ®Google Scholar
• Wang X, Khlystov A, Ho K-F, et al. Real-World Vehicle Emissions Characterization for the Shing Mun Tunnel in Hong Kong and Fort McHenry Tunnel in the United States. Res Rep Health Eff Inst. 2019;2019(199):5–52. PMID:31663714
   PubMedGoogle Scholar
• Jia C, Batterman S. A critical review of naphthalene sources and exposures relevant to indoor and outdoor air. Int J Environ Res Public Health. 2010;7(7):2903–2939. doi:10.3390/ijerph7072903.
   PubMed Web of Science ®Google Scholar
• Gong J, Zhu T, Kipen H, et al. Urinary polycyclic aromatic hydrocarbon metabolites as biomarkers of exposure to traffic-emitted pollutants. Environ Int. 2015;85:104–110. doi:10.1016/j.envint.2015.09.003.
   PubMed Web of Science ®Google Scholar
• Ekpenyong CE, Asuquo AE. Recent advances in occupational and environmental health hazards of workers exposed to gasoline compounds. Int J Occup Med Environ Health. 2017;30(1):1–26. doi:10.13075/ijomeh.1896.00800.
   PubMed Web of Science ®Google Scholar
• Alves LP, Vieira DSP, Nunes LSS, et al. Relationship between symptoms, use of PPE and habits related to occupational exposure to BTEX compounds in workers of gas stations in Bahia, Brazil. JEP. 2017;08(05):650–661. doi:10.4236/jep.2017.85042.
   Google Scholar
• Furey RL, Nagel BE. Composition of vapor emitted from a vehicle gasoline tank during refueling. SAE transactions. 1986;95(6):45–60.
   Google Scholar
• EPA. Chemicals in the Environment: 1,2,4-Trimethylbenzene (CAS NO. 95-63-6). 1994. United States Environmental Protection Agency (EPA). National Service Center for Environmental Publications (NSCEP).
   Google Scholar
• Järnberg J, Johanson G, Löf A. Toxicokinetics of inhaled trimethylbenzenes in man. Toxicol Appl Pharmacol. 1996;140(2):281–288. doi:10.1006/taap.1996.0223.
   PubMed Web of Science ®Google Scholar
• Bahrami AR, Joneidi Jafari A, Ahmadi H, et al. Comparison of benzene exposure in drivers and petrol stations workers by urinary trans,trans-muconic acid in west of Iran. Ind Health. 2007;45(3):396–401. doi:10.2486/indhealth.45.396.
   PubMed Web of Science ®Google Scholar
• Clough SR. Xylene. In: Wexler P, ed. Encyclopedia of Toxicology (3rd ed.). Oxford: Academic Press: 2014:989–992.
   Google Scholar
• Anand SS, Philip BK, Mehendale HM. Volatile organic compounds. In: Wexler P, ed. Encyclopedia of Toxicology (3rd ed.). Oxford: Academic Press; 2014:967–970.
   Google Scholar
• Okafoagu Nneka C, Oche Mansur O, Gana Godwin J, et al. Knowledge of occupational hazards and safety practices among petrol station attendants in Sokoto metropolis, Sokoto State, Nigeria. JOHE. 2017;6(3):122–127. doi:10.29252/johe.6.3.122.
   Google Scholar
• Kuranchie FA, Angnunavuri PN, Attiogbe F, et al. Occupational exposure of benzene, toluene, ethylbenzene and xylene (BTEX) to pump attendants in Ghana: Implications for policy guidance. Cogent Environ Sci. 2019;5(1):1603418. doi:10.1080/23311843.2019.1603418.
   Web of Science ®Google Scholar
• Singh A, Kamal R, Ahamed I, et al. PAH exposure-associated lung cancer: an updated meta-analysis. Occup Med (Lond). 2018;68(4):255–261. doi:10.1093/occmed/kqy049.
   PubMed Web of Science ®Google Scholar