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Original Research

Use of PrEP, sexual behaviors and mental health correlates in a sample of gay, bisexual and other men who have sex with men

, PhDORCID Icon, , PhDORCID Icon, , BA & , BA
Pages 94-111 | Received 20 Jan 2019, Accepted 29 Oct 2019, Published online: 14 Nov 2019

References

  • Alvy, L. M., McKirnan, D. J., Mansergh, G., Koblin, B., Colfax, G. N., Flores, S. A., & Hudson, S. (2011). Depression is associated with sexual risk among men who have sex with men, but is mediated by cognitive escape and self-efficacy. AIDS and Behavior, 15(6), 1171–1179. doi:10.1007/s10461-010-9678-z
  • Amola, O., & Grimmett, M. A. (2015). Sexual identity, mental health, HIV risk behaviors, and internalized homophobia among black men who have sex with men. Journal of Counseling & Development, 93(2), 236–246. doi:10.1002/j.1556-6676.2015.00199.x
  • Anderson, P. L., Glidden, D. V., Liu, A., Buchbinder, S., Lama, J. R., Guanira, J. V., … Grant, R. M. (2012). Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men. Science Translational Medicine, 4(151), 151ra125. doi:10.1126/scitranslmed.3004006
  • Bostwick, W. B., Boyd, C. J., Hughes, T. L., & McCabe, S. E. (2010). Dimensions of sexual orientation and the prevalence of mood and anxiety disorders in the United States. American Journal of Public Health, 100(3), 468–475. doi:10.2105/AJPH.2008.152942
  • Centers for Disease Control and Prevention (CDC). (2015). HIV prevention in the United States: New opportunities, new expectations. Retrieved from https://www.cdc.gov/hiv/pdf/policies/cdc-hiv-prevention-bluebook.pdf
  • Centers for Disease Control and Prevention (CDC). (2017). HIV surveillance report, 2016 (vol. 28). Retrieved from http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html
  • Cochran, S. D., Sullivan, J. G., & Mays, V. M. (2003). Prevalence of mental disorders, psychological distress, and mental health services use among lesbian, gay, and bisexual adults in the United States. Journal of Consulting and Clinical Psychology, 71(1), 53–61. doi:10.1037/0022-006X.71.1.53
  • Colfax, G., Vittinghoff, E., Husnik, M. J., McKirnan, D., Buchbinder, S., Koblin, B., … Mayer, K. (2004). Substance use and sexual risk: A participant-and episode-level analysis among a cohort of men who have sex with men. American Journal of Epidemiology, 159(10), 1002–1012. doi:10.1093/aje/kwh135
  • Crepaz, N., & Marks, G. (2001). Are negative affective states associated with HIV sexual risk behaviors? A meta-analytic review. Health Psychology, 20(4), 291–299. doi:10.1037//0278-6133.20.4.291
  • Feinstein, B. A., Goldfried, M. R., & Davila, J. (2012). The relationship between experiences of discrimination and mental health among lesbians and gay men: An examination of internalized homonegativity and rejection sensitivity as potential mechanisms. Journal of Consulting and Clinical Psychology, 80(5), 917–927. doi:10.1037/a0029425
  • U.S. Food & Drug Administration (2012). Truvada for PrEP fact sheet: Ensuring safe and proper use. Retrieved from https://www.fda.gov/media/83586/download
  • Golub, S. A., Kowalczyk, W., Weinberger, C. L., & Parsons, J. T. (2010). Preexposure prophylaxis and predicted condom use among high-risk men who have sex with men. JAIDS Journal of Acquired Immune Deficiency Syndromes, 54(5), 548–555. doi:10.1097/QAI.0b013e3181e19a54
  • Grant, R. M., Lama, J. R., Anderson, P. L., McMahan, V., Liu, A. Y., Vargas, L., … Glidden, D. V. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. New England Journal of Medicine, 363(27), 2587–2599. doi:10.1056/NEJMoa1011205
  • Grov, C., Whitfield, T. H., Rendina, H. J., Ventuneac, A., & Parsons, J. T. (2015). Willingness to take PrEP and potential for risk compensation among highly sexually active gay and bisexual men. AIDS and Behavior, 19(12), 2234–2244. doi:10.1007/s10461-015-1030-1
  • Guille, C., Frank, E., Zhao, Z., Kalmbach, D. A., Nietert, P. J., Mata, D. A., & Sen, S. (2017). Work-family conflict and the sex difference in depression among training physicians. JAMA Internal Medicine, 177(12), 1766–1772. doi:10.1001/jamainternmed.2017.5138
  • Herek, G. M. (2004). Beyond “homophobia”: Thinking about sexual prejudice and stigma in the twenty-first century. Sexuality Research and Social Policy, 1(2), 6–24. doi:10.1525/srsp.2004.1.2.6
  • Herek, G. M., Cogan, J. C., Gillis, J. R., & Glunt, E. K. (1998). Correlates of internalized homophobia in a community sample of lesbians and gay men. Journal of the Gay and Lesbian Medical Association, 2, 17–26.
  • Hoff, C. C., Chakravarty, D., Bircher, A. E., Campbell, C. K., Grisham, K., Neilands, T. B., … Dworkin, S. (2015). Attitudes towards PrEP and anticipated condom use among concordant HIV-negative and HIV-discordant male couples. AIDS Patient Care and Stds, 29(7), 408–417. doi:10.1089/apc.2014.0315
  • Houston, E., Sandfort, T., Dolezal, C., & Carballo-Diéguez, A. (2012). Depressive symptoms among MSM who engage in bareback sex: Does mood matter? AIDS and Behavior, 16(8), 2209–2215. doi:10.1007/s10461-012-0156-7
  • Igartua, K. J., Gill, K., & Montoro, R. (2003). Internalized homophobia: A factor in depression, anxiety, and suicide in the gay and lesbian population. Canadian Journal of Community Mental Health, 22(2), 15–30. doi:10.7870/cjcmh-2003-0011
  • Jie, W., Ciyong, L., Xueqing, D., Hui, W., & Lingyao, H. (2012). A syndemic of psychosocial problems places the MSM (men who have sex with men) population at greater risk of HIV infection. PloS One, 7(3), e32312. doi:10.1371/journal.pone.0032312
  • King, M., Semlyen, J., Tai, S. S., Killaspy, H., Osborn, D., Popelyuk, D., & Nazareth, I. (2008). A systematic review of mental disorder, suicide, and deliberate self harm in lesbian, gay and bisexual people. BMC Psychiatry, 8(1), 70. doi:10.1186/1471-244X-8-70
  • Krakower, D. S., Mimiaga, M. J., Rosenberger, J. G., Novak, D. S., Mitty, J. A., White, J. M., & Mayer, K. H. (2012). Limited awareness and low immediate uptake of pre-exposure prophylaxis among men who have sex with men using an internet social networking site. PloS One, 7(3), e33119. doi:10.1371/journal.pone.0033119
  • Kroenke, K., Spitzer, R. L., & Williams, J. B. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9), 606–613. doi:10.1046/j.1525-1497.2001.016009606.x
  • Liu, A. Y., Vittinghoff, E., Chillag, K., Mayer, K., Thompson, M., Grohskopf, L., … Buchbinder, S. P. (2013). Sexual risk behavior among HIV-uninfected men who have sex with men (MSM) participating in a tenofovir pre-exposure prophylaxis (PrEP) randomized trial in the United States. JAIDS Journal of Acquired Immune Deficiency Syndromes, 64(1), 87–94. doi:10.1097/QAI.0b013e31828f097a
  • Mantell, J. E., Sandfort, T. G., Hoffman, S., Guidry, J. A., Masvawure, T. B., & Cahill, S. (2014). Knowledge and attitudes about preexposure prophylaxis (PrEP) among sexually active men who have sex with men and who participate in New York City Gay Pride events. LGBT Health, 1(2), 93–97. doi:10.1089/lgbt.2013.0047
  • Mehrotra, M. L., Glidden, D. V., McMahan, V., Amico, K. R., Hosek, S., Defechereux, P., … Grant, R. M. (2016). The effect of depressive symptoms on adherence to daily oral PrEP in men who have sex with men and transgender women: A marginal structural model analysis of the iPrEx OLE Study. AIDS and Behavior, 20(7), 1527–1534. doi:10.1007/s10461-016-1415-9
  • Mera Giler, R., Trevor, H., Bush, S., Rawlings, K., & McCallister, S. (2017). Changes in truvada (TVD) for HIV pre-exposure prophylaxis (PrEP) utilization in the United States (2012–2016). Presented at the 9th International AIDS Society Conference on HIV Science, 23–26, Paris, France.
  • Meyer, I. H. (2003). Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: Conceptual issues and research evidence. Psychological Bulletin, 129(5), 674–697. doi:10.1037/0033-2909.129.5.674
  • Newcomb, M. E., & Mustanski, B. (2011). Moderators of the relationship between internalized homophobia and risky sexual behavior in men who have sex with men: A meta-analysis. Archives of Sexual Behavior, 40(1), 189–199. doi:10.1007/s10508-009-9573-8
  • Pereira, L. F., Goschin, S., & Ashley, K. B. (2016). PrEP: A review for mental health professionals. Journal of Gay & Lesbian Mental Health, 20(1), 4–12. doi:10.1080/19359705.2015.1106221
  • Reisner, S. L., Mimiaga, M. J., Skeer, M., Bright, D., Cranston, K., Isenberg, D., … Mayer, K. H. (2009). Clinically significant depressive symptoms as a risk factor for HIV infection among Black MSM in Massachusetts. AIDS and Behavior, 13(4), 798–810. doi:10.1007/s10461-009-9571-9
  • Rosario, M., Schrimshaw, E. W., & Hunter, J. (2006). A model of sexual risk behaviors among young gay and bisexual men: Longitudinal associations of mental health, substance abuse, sexual abuse, and the coming-out process. AIDS Education and Prevention, 18(5), 444–460. doi:10.1521/aeap.2006.18.5.444
  • Safren, S. A., Reisner, S. L., Herrick, A., Mimiaga, M. J., & Stall, R. (2010). Mental health and HIV risk in men who have sex with men. JAIDS Journal of Acquired Immune Deficiency Syndromes, 55(Suppl 2), S74–S77. doi:10.1097/QAI.0b013e3181fbc939
  • Smith, D. K., Mendoza, M. C., Stryker, J. E., & Rose, C. E. (2016). PrEP awareness and attitudes in a national survey of primary care clinicians in the United States, 2009–2015. PLoS One, 11(6), e0156592. doi:10.1371/journal.pone.0156592
  • Spieldenner, A. (2016). PrEP whores and HIV prevention: The queer communication of HIV pre-exposure prophylaxis (PrEP). Journal of Homosexuality, 63(12), 1685–1697. doi:10.1080/00918369.2016.1158012
  • Spitzer, R. L., Kroenke, K., Williams, J. B., & Löwe, B. (2006). A brief measure for assessing generalized anxiety disorder: The GAD-7. Archives of Internal Medicine, 166(10), 1092–1097. doi:10.1001/archinte.166.10.1092
  • Stall, R., Mills, T. C., Williamson, J., Hart, T., Greenwood, G., Paul, J., … Catania, J. A. (2003). Association of co-occurring psychosocial health problems and increased vulnerability to HIV/AIDS among urban men who have sex with men. American Journal of Public Health, 93(6), 939–942. doi:10.2105/AJPH.93.6.939
  • Stall, R., Paul, J. P., Greenwood, G., Pollack, L. M., Bein, E., Crosby, G. M., … Catania, J. A. (2001). Alcohol use, drug use and alcohol-related problems among men who have sex with men: The Urban Men’s Health Study. Addiction, 96(11), 1589–1601. doi:10.1046/j.1360-0443.2001.961115896.x
  • Sullivan, P. S., Smith, D. K., Mera Giler, R., Siddiqi, A.-A., Gunnels, B., Harris, N., … McCallister, S. (2018). The impact of pre-exposure prophylaxis with FTC/TDF on HIV diagnoses, 2012–2016, United States. Retrieved from http://www.natap.org/2018/IAC/IAC_17.htm
  • Tan, D. H., Leon-Carlyle, M., Mills, R., Moses, E., & Carvalhal, A. (2016). Self-administered screening for Syndemic mental health problems should be routinely implemented among MSM PrEP users. Journal of Gay & Lesbian Mental Health, 20(1), 13–20. doi:10.1080/19359705.2015.1105765
  • Tao, J., Qian, H.-Z., Kipp, A. M., Ruan, Y., Shepherd, B. E., Amico, K. R., … Vermund, S. H. (2017). Effects of depression and anxiety on antiretroviral therapy adherence among newly diagnosed HIV-infected Chinese MSM. AIDS, 31(3), 401–406. doi:10.1097/QAD.0000000000001287
  • Tripathi, A., Whiteside, Y. O., & Duffus, W. A. (2013). Perceptions and attitudes about preexposure prophylaxis among seronegative partners and the potential of sexual disinhibition. Southern Medical Journal, 106(10), 558–564.
  • Volk, J. E., Marcus, J. L., Phengrasamy, T., Blechinger, D., Nguyen, D. P., Follansbee, S., & Hare, C. B. (2015). No new HIV infections with increasing use of HIV preexposure prophylaxis in a clinical practice setting. Clinical Infectious Diseases, 61(10), 1601–1603. doi:10.1093/cid/civ778
  • Whitfield, T. H., John, S. A., Rendina, H. J., Grov, C., & Parsons, J. T. (2018). Why i quit pre-exposure prophylaxis (PrEP)? A mixed-method study exploring reasons for PrEP discontinuation and potential re-initiation among gay and bisexual men. AIDS and Behavior, 22(11), 3566–3575. doi:10.1007/s10461-018-2045-1
  • World Health Organization (WHO). (2014). Policy brief: Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. Retrieved from https://apps.who.int/iris/bitstream/handle/10665/128048/9789241507431_eng.pdf?sequence=1
  • World Health Organization (WHO). (2015). Pre-exposure prophylaxis (PrEP): WHO expands recommendation on oral pre-exposure prophylaxis of HIV infection (PrEP). Retrieved from https://apps.who.int/iris/bitstream/handle/10665/197906/WHO_HIV_2015.48_eng.pdf?sequence=1

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