Analysis of COVID-19 Pandemic on Supplement Usage and Its Combination with Self-Medication within the State of Arkansas

References

• Pascarella G, Strumia A, Piliego C, Bruno F, Del Buono R, Costa F, Scarlata S, Agrò FE. COVID-19 diagnosis and management: a comprehensive review. J Intern Med. 2020;288(2):192–206. doi:10.1111/joim.13091.
   PubMed Web of Science ®Google Scholar
• Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. Jama. 2020;323(11):1061–9. doi:10.1001/jama.2020.1585.
   PubMed Web of Science ®Google Scholar
• Bull-Otterson L, Gray EB, Budnitz DS, Strosnider HM, Schieber LZ, Courtney J, García MC, Brooks JT, Mac Kenzie WR, Gundlapalli AV, et al. Hydroxychloroquine and chloroquine prescribing patterns by provider specialty following initial reports of potential benefit for COVID-19 treatment - United States, January–June 2020. MMWR Morbidity Mortal Weekly Rep. 2020;69(35):1210–5. doi:10.15585/mmwr.mm6935a4.
   PubMed Web of Science ®Google Scholar
• Grebow J. Dietary supplement sales skyrocket during coronavirus pandemic. Nutr Outlook. 2020;23.
   Google Scholar
• Nutrition CfR. Dietary Supplement usage up dramatically during pandemic, New Ipsos-CRN Survey Shows. Washington, DC, 2020.
   Google Scholar
• Adams KK, Baker WL, Sobieraj DM. Myth busters: dietary supplements and COVID-19. Ann Pharmacother. 2020;54(8):820–6. doi:10.1177/1060028020928052.
   PubMed Web of Science ®Google Scholar
• Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O’Neal L, McLeod L, Delacqua G, Delacqua F, Kirby J, et al. The REDCap consortium: Building an international community of software platform partners. J Biomed Inform. 2019;95:103208. doi:10.1016/j.jbi.2019.103208.
   PubMed Web of Science ®Google Scholar
• Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–81. doi:10.1016/j.jbi.2008.08.010.
   PubMed Web of Science ®Google Scholar
• WHO. Coronavirus prevention: symptoms; 2020. https://www.who.int/health-topics/coronavirus#tab=tab_3
   Google Scholar
• Burke RM, Killerby ME, Newton S, Ashworth CE, Berns AL, Brennan S, Bressler JM, Bye E, Crawford R, Harduar Morano L, et al. Symptom profiles of a convenience sample of patients with COVID-19 - United States, January–April 2020. MMWR Morbidity Mortal Weekly Rep. 2020;69(28):904–8. doi:10.15585/mmwr.mm6928a2.
   PubMed Web of Science ®Google Scholar
• Anderson TW, Reid DB, Beaton GH. Vitamin C and the common cold: a double-blind trial. Can Med Assoc J. 1972;107:503–8.
   PubMedGoogle Scholar
• Hemilä H. Vitamin C and the common cold. Br J Nutr. 1992;67(1):3–16. doi:10.1079/bjn19920004.
   PubMed Web of Science ®Google Scholar
• Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2013;2013(1):CD000980. doi: 10.1002/14651858.CD000980.pub4.
   PubMedGoogle Scholar
• Annweiler G, Corvaisier M, Gautier J, Dubée V, Legrand E, Sacco G, Annweiler C. Vitamin D supplementation associated to better survival in hospitalized frail elderly COVID-19 patients: the GERIA-COVID quasi-experimental study. Nutrients. 2020;12(11):3377. doi:10.3390/nu12113377.
   PubMed Web of Science ®Google Scholar
• Ferrari D, Locatelli M. No significant association between vitamin D and COVID-19. A retrospective study from a northern Italian hospital. Int J Vitam Nutr Res. 2021;91(3-4):200–203. doi: 10.1024/0300-9831/a000687
   PubMed Web of Science ®Google Scholar
• Grant WB, Lahore H, McDonnell SL, et al. Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients. 2020;12(4):988. doi: 10.3390/nu12040988.
   PubMed Web of Science ®Google Scholar
• Pérez-López FR, Chedraui P, Pilz S. Vitamin D supplementation after the menopause. Ther Adv Endocrinol Metab. 2020;11:2042018820931291. doi:10.1177/2042018820931291.
   Web of Science ®Google Scholar
• Raharusun P. Patterns of COVID-19 mortality and vitamin D: an Indonesian study. SSRN Electron. 2020;7:1–12.
   Google Scholar
• Henrina J, Lim MA, Pranata R. COVID-19 and misinformation: how an infodemic fuelled the prominence of vitamin D. Br J Nutr. 2021;125(3):359–60. doi:10.1017/S0007114520002950.
   PubMed Web of Science ®Google Scholar
• Rubin R. Sorting out whether vitamin D deficiency raises COVID-19 risk. JAMA. 2021;325(4):329–30. doi:10.1001/jama.2020.24127.
   PubMed Web of Science ®Google Scholar
• Infusino F, Marazzato M, Mancone M, Fedele F, Mastroianni CM, Severino P, Ceccarelli G, Santinelli L, Cavarretta E, Marullo AGM, et al. Diet supplementation, probiotics, and nutraceuticals in SARS-CoV-2 infection: a scoping review. Nutrients. 2020;12(6):1718. doi:10.3390/nu12061718.
   PubMed Web of Science ®Google Scholar
• Shakoor H, Feehan J, Al Dhaheri AS, Ali HI, Platat C, Ismail LC, Apostolopoulos V, Stojanovska L. Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: could they help against COVID-19? Maturitas. 2021;143:1–9. doi:10.1016/j.maturitas.2020.08.003.
   PubMed Web of Science ®Google Scholar
• Shakoor H, Feehan J, Mikkelsen K, Al Dhaheri AS, Ali HI, Platat C, Ismail LC, Stojanovska L, Apostolopoulos V. Be well: a potential role for vitamin B in COVID-19. Maturitas. 2021;144:108–11. doi:10.1016/j.maturitas.2020.08.007.
   PubMed Web of Science ®Google Scholar
• Keil SD, Bowen R, Marschner S. Inactivation of Middle East respiratory syndrome coronavirus (MERS-CoV) in plasma products using a riboflavin-based and ultraviolet light-based photochemical treatment. Transfusion. 2016;56(12):2948–52. doi:10.1111/trf.13860.
   PubMed Web of Science ®Google Scholar
• Michele CA, BA, Valeria L, Teresa M, Pasquale DL, Giuseppe C, Giovanni M, Michele DP, Ernestina P, Mario B. Vitamin supplements in the Era of SARS-Cov2 pandemic. GSC Biol. and Pharm. Sci. 2020;11(2):007–19. doi:10.30574/gscbps.2020.11.2.0114.
   Google Scholar
• Zhang L, Liu Y. Potential interventions for novel coronavirus in China: a systematic review. J Med Virol. 2020;92(5):479–90. doi:10.1002/jmv.25707.
   PubMed Web of Science ®Google Scholar
• Kumar A, Kubota Y, Chernov M, Kasuya H. Potential role of zinc supplementation in prophylaxis and treatment of COVID-19. Med Hypotheses. 2020;144:109848– doi:10.1016/j.mehy.2020.109848.
   PubMed Web of Science ®Google Scholar
• Skalny AV, Rink L, Ajsuvakova OP, Aschner M, Gritsenko VA, Alekseenko SI, Svistunov AA, Petrakis D, Spandidos DA, Aaseth J, et al. Zinc and respiratory tract infections: perspectives for COVID‑19 (review). Int J Mol Med. 2020;46(1):17–26. doi:10.3892/ijmm.2020.4575.
   PubMed Web of Science ®Google Scholar
• Finzi E. Treatment of SARS-CoV-2 with high dose oral zinc salts: a report on four patients. Int J Infect Dis. 2020;99:307–9. doi:10.1016/j.ijid.2020.06.006.
   PubMed Web of Science ®Google Scholar
• Walker LA, Koturbash I, Kingston R, ElSohly MA, Yates CR, Gurley BJ, Khan I. Cannabidiol (CBD) in dietary supplements: perspectives on science, safety, and potential regulatory approaches. J Diet Suppl. 2020;17(5):493–502. doi:10.1080/19390211.2020.1777244.
   PubMedGoogle Scholar
• Weng J-R, Lin C-S, Lai H-C, Lin Y-P, Wang C-Y, Tsai Y-C, Wu K-C, Huang S-H, Lin C-W. Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63. Virus Res. 2019;273:197767– doi:10.1016/j.virusres.2019.197767.
   PubMed Web of Science ®Google Scholar
• Wieland LS, Piechotta V, Feinberg T, Ludeman E, Hutton B, Kanji S, Seely D, Garritty C. Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review. BMC Complement Med Ther. 2021;21(1):112. doi:10.1186/s12906-021-03283-5.
   PubMedGoogle Scholar
• Singletary K. Turmeric: potential health benefits. Nutr Today. 2020;55(1):45–56. doi:10.1097/NT.0000000000000392.
   Google Scholar
• Babaei F, Nassiri-Asl M, Hosseinzadeh H. Curcumin (a constituent of turmeric): new treatment option against COVID-19. Food Sci Nutr. 2020;8(10):5215–27. doi:10.1002/fsn3.1858.
   PubMed Web of Science ®Google Scholar
• Das S, Bhowmick S, Tiwari S, Sen S. An updated systematic review of the therapeutic role of hydroxychloroquine in coronavirus disease-19 (COVID-19). Clin Drug Investig. 2020;40(7):591–601. doi:10.1007/s40261-020-00927-1.
   PubMed Web of Science ®Google Scholar
• Sanders JM, Monogue ML, Jodlowski TZ, Cutrell JB. Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review. Jama. 2020;323(18):1824–36. doi:10.1001/jama.2020.6019.
   PubMed Web of Science ®Google Scholar
• Cathey L. Timeline: tracking Trump alongside scientific developments on hydroxychloroquine; 2020. https://abcnews.go.com/Health/timeline-tracking-trump-alongside-scientific-developments-hydroxychloroquine/story?id=72170553
   Google Scholar
• Silva Borba MG, Almeida VF, Sampaio VS, et al. Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study). medRxiv. 2020:2020.2004.2007.20056424.
   Google Scholar
• Rosenberg ES, Dufort EM, Udo T, Wilberschied LA, Kumar J, Tesoriero J, Weinberg P, Kirkwood J, Muse A, DeHovitz J, et al. Association of treatment with hydroxychloroquine or azithromycin with in-hospital mortality in patients with COVID-19 in New York State. JAMA. 2020;323(24):2493–502. doi:10.1001/jama.2020.8630.
   PubMed Web of Science ®Google Scholar
• Vaduganathan M, van Meijgaard J, Mehra MR, Joseph J, O’Donnell CJ, Warraich HJ. Prescription fill patterns for commonly used drugs during the COVID-19 pandemic in the United States. JAMA. 2020;323(24):2524–6. doi:10.1001/jama.2020.9184.
   PubMed Web of Science ®Google Scholar
• Chahin A, Dhabaan G, Buhaish A, et al. Medications and supplements prescription patterns during COVID 19 pandemic in Yemen: a questionnaire-based study. 2021.
   Google Scholar
• Sterne JAC, Murthy S, Diaz JV, Slutsky AS, Villar J, Angus DC, Annane D, Azevedo LCP, Berwanger O, Cavalcanti AB, et al. Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis. Jama. 2020;324(13):1330–41. doi:10.1001/jama.2020.17023.
   PubMed Web of Science ®Google Scholar
• Horby P, Lim WS, Emberson JR, et al. Dexamethasone in hospitalized patients with Covid-19. N Engl J Med. 2021;384:693–704.
   PubMed Web of Science ®Google Scholar
• Waljee AK, Rogers MAM, Lin P, Singal AG, Stein JD, Marks RM, Ayanian JZ, Nallamothu BK. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study. BMJ. 2017;357:j1415. doi:10.1136/bmj.j1415.
   PubMed Web of Science ®Google Scholar
• Kullar R, Marcelin JR, Swartz TH, Piggott DA, Macias Gil R, Mathew TA, Tan T. Racial disparity of coronavirus disease 2019 in African American Communities. J Infect Dis. 2020;222(6):890–3. doi:10.1093/infdis/jiaa372.
   PubMed Web of Science ®Google Scholar
• Louis-Jean J, Cenat K, Njoku CV, Angelo J, Sanon D. Coronavirus (COVID-19) and racial disparities: a perspective analysis. J Racial Ethn Health Disparities. 2020;7(6):1039–45. doi:10.1007/s40615-020-00879-4.
   PubMed Web of Science ®Google Scholar