References
- Alfarawati S, Fragouli E, Colls P, Stevens J, Gutiérrez-Mateo C, Schoolcraft WB, Katz-Jaffe MG, Wells D. 2011. The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender. Fertil Steril. 95(2):520–524. http://www.ncbi.nlm.nih.gov/pubmed/20537630.
- Ata B, Kaplan B, Danzer H, Glassner M, Opsahl M, Tan SL, Munné S. 2012. Array CGH analysis shows that aneuploidy is not related to the number of embryos generated. Reprod Biomed Online. 24(6):614–620. http://www.ncbi.nlm.nih.gov/pubmed/22503277.
- Baart EB, Martini E, Eijkemans MJ, Van Opstal D, Beckers NGM, Verhoeff A, Macklon NS, Fauser BCJM. 2007. Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial. Hum Reprod. 22(4):980–988. http://www.ncbi.nlm.nih.gov/pubmed/17204525.
- Babariya D, Fragouli E, Alfarawati S, Spath K, Wells D. 2017. The incidence and origin of segmental aneuploidy in human oocytes and preimplantation embryos. Hum Reprod. 32(12):2549–2560. http://www.ncbi.nlm.nih.gov/pubmed/29126206.
- Balasch J, Vidal E, Peñarrubia J, Casamitjana R, Carmona F, Creus M, Fábregues F, Vanrell JA. 2001. Suppression of LH during ovarian stimulation: analysing threshold values and effects on ovarian response and the outcome of assisted reproduction in down-regulated women stimulated with recombinant FSH. Hum Reprod. 16(8):1636–1643. https://academic.oup.com/humrep/article-lookup/doi/10.1093/humrep/16.8.1636.
- Barash OO, Hinckley MD, Rosenbluth EM, Ivani KA, Weckstein LN. 2017. High gonadotropin dosage does not affect euploidy and pregnancy rates in IVF PGS cycles with single embryo transfer. Hum Reprod. 32(11):2209–2217. http://www.ncbi.nlm.nih.gov/pubmed/29040519.
- Capalbo A, Rienzi L, Cimadomo D, Maggiulli R, Elliott T, Wright G, Nagy ZP, Ubaldi FM. 2014. Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts. Hum Reprod. 29(6):1173–1181. http://www.ncbi.nlm.nih.gov/pubmed/24578475.
- de Ziegler D, Jaaskelainen AS, Brioschi PA, Fanchin R, Bulletti C. 1998. Synchronization of endogenous and exogenous FSH stimuli in controlled ovarian hyperstimulation (COH). Hum Reprod. 13(3):561–564. https://academic.oup.com/humrep/article-lookup/doi/10.1093/humrep/13.3.561.
- Engmann L, DiLuigi A, Schmidt D, Nulsen J, Maier D, Benadiva C. 2008. The use of gonadotropin-releasing hormone (GnRH) agonist to induce oocyte maturation after cotreatment with GnRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective randomized controlled study. Fertil Steril. 89(1):84–91. https://linkinghub.elsevier.com/retrieve/pii/S001502820700338X.
- Griffin D, Feinn R, Engmann L, Nulsen J, Budinetz T, Benadiva C. 2014. Dual trigger with gonadotropin-releasing hormone agonist and standard dose human chorionic gonadotropin to improve oocyte maturity rates. Fertil Steril. 102(2):405–409.
- Hodes-Wertz B, Grifo J, Ghadir S, Kaplan B, Laskin CA, Glassner M, Munné S. 2012. Idiopathic recurrent miscarriage is caused mostly by aneuploid embryos. Fertil Steril. 98(3):675–680. https://linkinghub.elsevier.com/retrieve/pii/S0015028212005791.
- Hong K. H., Franasiak J. M., Werner M. M., Patounakis, G., Juneau C. R., Forman E. J., and Scott R. T. 2019. Embryonic aneuploidy rates are equivalent in natural cycles and gonadotropin-stimulated cycles. 112(4):670–676.
- Kuliev A, Verlinsky Y. 2004. Meiotic and mitotic nondisjunction: lessons from preimplantation genetic diagnosis. Hum Reprod. 10(5):401–407. http://www.ncbi.nlm.nih.gov/pubmed/15319376.
- Labarta E, Bosch E, Mercader A, Alamá P, Mateu E, Pellicer A. 2017. A higher ovarian response after stimulation for IVF is related to a higher number of euploid embryos. Biomed Res Int. 2017:1–8. http://www.ncbi.nlm.nih.gov/pubmed/28428962.
- Macklon NS, Stouffer RL, Giudice LC, Fauser BCJM. 2006. The science behind 25 years of ovarian stimulation for in vitro fertilization. Endocr Rev. 27(2):170–207. https://academic.oup.com/edrv/article/27/2/170/2355253.
- MacLennan M, Crichton JH, Playfoot CJ, Adams IR. 2015. Oocyte development, meiosis and aneuploidy. Semin Cell Dev Biol. 45:68–76. http://www.ncbi.nlm.nih.gov/pubmed/26454098.
- McCulloh DH, Alikani M, Norian J, Kolb B, Arbones JM, Munné S. 2019. Controlled ovarian hyperstimulation (COH) parameters associated with euploidy rates in donor oocytes. Eur J Med Genet. 62(8):103707.
- Mochtar MH, Van der Veen F, Ziech M, van Wely M, Musters A. 2007. Recombinant Luteinizing Hormone (rLH) for controlled ovarian hyperstimulation in assisted reproductive cycles. In: Mochtar MH, editor. Cochrane database system review. Vol. 2. p. CD005070. doi:10.1002/14651858.CD005070.pub2.
- Morin S, Melzer-Ross K, McCulloh D, Grifo J, Munné S. 2014. A greater number of euploid blastocysts in a given cohort predicts excellent outcomes in single embryo transfer cycles. J Assist Reprod Genet. 31(6):667–673.
- Munné S, Alikani M, Ribustello L, Colls P, Martínez-Ortiz PA, McCulloh DH, Referring Physician Group. 2017. Euploidy rates in donor egg cycles significantly differ between fertility centers. Hum Reprod. 32(4):743–749. http://www.ncbi.nlm.nih.gov/pubmed/28333245.
- Munné S, Chen S, Colls P, Garrisi J, Zheng X, Cekleniak N, Lenzi M, Hughes P, Fischer J, Garrisi M, et al. 2007. Maternal age, morphology, development and chromosome abnormalities in over 6000 cleavage-stage embryos. Reprod Biomed Online. 14(5):628–634. https://linkinghub.elsevier.com/retrieve/pii/S1472648310610577
- Munne S, Magli C, Adler A, Wright G, de Boer K, Mortimer D, Tucker M, Cohen J, Gianaroli L. 1997. Treatment-related chromosome abnormalities in human embryos. Hum Reprod. 12(4):780–784. http://www.ncbi.nlm.nih.gov/pubmed/9159442.
- Nargund G, Waterstone J, Bland J, Philips Z, Parsons J, Campbell S. 2001. Cumulative conception and live birth rates in natural (unstimulated) IVF cycles. Hum Reprod. 16(2):259–262. http://www.ncbi.nlm.nih.gov/pubmed/11157816.
- Neal SA, Werner MD. 2018. The impact of contemporary preimplantation genetic screening and diagnosis on the detection of aneuploidy and inherited genetic diseases. Birth Defects Res. 110(8):644–647. http://www.ncbi.nlm.nih.gov/pubmed/29714058.
- Pacchierotti F, Adler I-D, Eichenlaub-Ritter U, Mailhes JB. 2007. Gender effects on the incidence of aneuploidy in mammalian germ cells. Environ Res. 104(1):46–69. http://www.ncbi.nlm.nih.gov/pubmed/17292877.
- Patrizio P, Sakkas D. 2009. From oocyte to baby: a clinical evaluation of the biological efficiency of in vitro fertilization. Fertil Steril. 91(4):1061–1066. https://linkinghub.elsevier.com/retrieve/pii/S0015028208000253.
- Sato A, Otsu E, Negishi H, Utsunomiya T, Arima T. 2007. Aberrant DNA methylation of imprinted loci in superovulated oocytes. Hum Reprod. 22(1):26–35. http://academic.oup.com/humrep/article/22/1/26/2939070/Aberrant-DNA-methylation-of-imprinted-loci-in.
- Sekhon L, Shaia K, Santistevan A, Cohn KH, Lee JA, Beim PY, Copperman AB. 2017. The cumulative dose of gonadotropins used for controlled ovarian stimulation does not influence the odds of embryonic aneuploidy in patients with normal ovarian response. J Assist Reprod Genet. 34(6):749–758. http://www.ncbi.nlm.nih.gov/pubmed/28321529.
- Thorne J, Loza A, Kaye L, Nulsen J, Benadiva C, Grow D, Engmann L. 2019. Euploidy rates between cycles triggered with gonadotropin-releasing hormone agonist and human chorionic gonadotropin. Fertil Steril. 112(2):258–265. https://linkinghub.elsevier.com/retrieve/pii/S0015028219303231.
- Vanneste E, Voet T, Melotte C, Debrock S, Sermon K, Staessen C, Liebaers I, Fryns J-P, D’Hooghe T, Vermeesch JR. 2009. What next for preimplantation genetic screening? High mitotic chromosome instability rate provides the biological basis for the low success rate. Hum Reprod. 24(11):2679–2682. http://www.ncbi.nlm.nih.gov/pubmed/19633308.
- Verpoest W, Fauser BC, Papanikolaou E, Staessen C, Van Landuyt L, Donoso P, Tournaye H, Liebaers I, Devroey P. 2008. Chromosomal aneuploidy in embryos conceived with unstimulated cycle IVF. Hum Reprod. 23(10):2369–2371. http://www.ncbi.nlm.nih.gov/pubmed/18621755.
- Weghofer A, Munné S, Brannath W, Chen S, Barad D, Cohen J, Gleicher N. 2009. The impact of LH-containing gonadotropin stimulation on euploidy rates in preimplantation embryos: antagonist cycles. Fertil Steril. 92(3):937–942. https://linkinghub.elsevier.com/retrieve/pii/S0015028208032688.
- Weghofer A, Munné S, Brannath W, Chen S, Tomkin G, Cekleniak N, Garrisi M, Barad D, Cohen J, Gleicher N. 2008. The impact of LH-containing gonadotropins on diploidy rates in preimplantation embryos: long protocol stimulation. Hum Reprod. 23(3):499–503. https://academic.oup.com/humrep/article-lookup/doi/10.1093/humrep/dem412.
- Wu Q, Li H, Zhu Y, Jiang W, Lu J, Wei D, Yan J, Chen Z-J. 2018. Dosage of exogenous gonadotropins is not associated with blastocyst aneuploidy or live-birth rates in PGS cycles in Chinese women. Hum Reprod. 33(10):1875–1882. http://www.ncbi.nlm.nih.gov/pubmed/30137360.