References
- Arutjunyan AV, Milyutina YP, Shcherbitskaia AD, Kerkeshko GO, Zalozniaia IV, Mikhel AV. 2020. Neurotrophins of the fetal brain and placenta in prenatal hyperhomocysteinemia. Biochemistry (Mosc). 85(2):213–223. doi:https://doi.org/10.1134/S000629792002008X.
- Atia TA. 2017. Placental apoptosis in recurrent miscarriage. Kaohsiung J Med Sci. 33(9):449–452. doi:https://doi.org/10.1016/j.kjms.2017.06.012.
- Austgulen R, Isaksen CV, Chedwick L, Romundstad P, Vatten L, Craven C. 2004. Preeclampsia: associated with increased syncytial apoptosis when the infant is small-for-gestational-age. J Reprod Immunol. 61(1):39–50. doi:https://doi.org/10.1016/j.jri.2003.10.001.
- Bertrand MJ, Kenchappa RS, Andrieu D, Leclercq-Smekens M, Nguyen HN, Carter BD, Muscatelli F, Barker PA, De Backer O. 2008. NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death Differ. 15(12):1921–1929. doi:https://doi.org/10.1038/cdd.2008.127.
- Bhakar AL, Howell JL, Paul CE, Salehi AH, Becker EB, Said F, Bonni A, Barker PA. 2003. Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad. J Neurosci. 23(36):11373–11381. doi:https://doi.org/10.1523/JNEUROSCI.23-36-11373.2003.
- Black S, Kadyrov M, Kaufmann P, Ugele B, Emans N, Huppertz B. 2004. Syncytial fusion of human trophoblast depends on caspase 8. Cell Death Differ. 11(1):90–98. doi:https://doi.org/10.1038/sj.cdd.4401307.
- Burton GJ, Skepper JN, Hempstock J, Cindrova T, Jones CJP, Jauniaux E. 2003. A reappraisal of the contrasting morphological appearances of villous cytotrophoblast cells during early human pregnancy; evidence for both apoptosis and primary necrosis. Placenta. 24:297–305. doi:https://doi.org/10.1053/plac.2002.0882.
- Casciaro A, Arcuri F, Occhini R, Toti MS, CDe F, Toti P. 2009. Expression of placental neurotrophin-3 (NT-3) in physiological pregnancy, preeclampsia and chorioamnionitis. Clin Med Pathol. 11(2):9–15.
- Chen Y, Huang Y, Jiang R, Teng Y. 2012. Syncytiotrophoblast-derived microparticle shedding in early-onset and late-onset severe preeclampsia. Int J Gynaecol Obstet. 119(3):234–238. doi:https://doi.org/10.1016/j.ijgo.2012.07.010.
- Chow R, Wessels JM, Foster WG. 2020. Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive tract. Hum Reprod Update. 26(4):545–564. doi:https://doi.org/10.1093/humupd/dmaa008.
- D’Arcy MS. 2019. Cell death: a review of the major forms of apoptosis, necrosis and autophagy. Cell Biol Int. 43(6):582–592. doi:https://doi.org/10.1002/cbin.11137.
- D’Souza V, Patil V, Pisal H, Randhir K, Joshi A, Mehendale S, Wagh G, Gupte S, Joshi S. 2014. Levels of brain derived neurotrophic factors across gestation in women with preeclampsia. Int J Dev Neurosci. 37:36–40. doi:https://doi.org/10.1016/j.ijdevneu.2014.06.008.
- Dagdelen M, Temur M, Ö Y, Altındag T, Uslu T, Özbay PÖ. 2016. Placental bed apoptosis is increased in pregnant women with preeclampsia versus normotensive pregnant women. J Obstet Gynaecol. 36(8):974–979. doi:https://doi.org/10.1080/01443615.2016.1178221.
- Daher S, Guimarães AJ, Mattar R, Ishigai MM, Barreiro EG, Bevilacqua E. 2008. Bcl-2 and Bax expressions in pre-term, term and post-term placentas. Am J Reprod Immunol. 60(2):172–178. doi:https://doi.org/10.1111/j.1600-0897.2008.00609.x.
- De Falco M, Fedele V, Cobellis L, Mastrogiacomo A, Leone S, Giraldi D, De Luca B, Laforgia V, De Luca A. 2004. Immunohistochemical distribution of proteins belonging to the receptor-mediated and the mitochondrial apoptotic pathways in human placenta during gestation. Cell Tissue Res. 318:599–608. doi:https://doi.org/10.1007/s00441-004-0969-4.
- DeFreitas MF, McQuillen PS, Shatz CJ. 2001. A novel p75NTR signaling pathway promotes survival, not death, of immunopurified neocortical subplate neurons. J Neurosci. 21(14):5121–5129. doi:https://doi.org/10.1523/JNEUROSCI.21-14-05121.2001.
- Demendi C, Börzsönyi B, Végh V, Nagy ZB, Jr RJ, Pajor A, Joó JG. 2012. Gene expression patterns of the Bcl-2 and Bax genes in preterm birth. Acta Obstet Gynecol Scand. 91(10):1212–1217. doi:https://doi.org/10.1111/j.1600-0412.2012.01428.x.
- Dhobale M, Mehendale S, Pisal H, D’Souza V, Joshi SR. 2012a. Association of brain-derived neurotrophic factor and tyrosine kinase B receptor in pregnancy. Neuroscience.216. 216(2):31–37. doi:https://doi.org/10.1016/j.neuroscience.2012.04.016.
- Dhobale M, Mehendale S, Pisal H, Nimbargi V, Joshi S. 2012b. Reduced maternal and cord nerve growth factor levels in preterm deliveries. Int J Dev Neurosci. 30(2):99–103. doi:https://doi.org/10.1016/j.ijdevneu.2011.12.007.
- Dhobale M, Pisal H, Mehendale S, Joshi S. 2013. Differential expression of human placental neurotrophic factors in preterm and term deliveries. Int J Dev Neurosci. 31(8):719–723. doi:https://doi.org/10.1016/j.ijdevneu.2013.09.006.
- DiFederico E, Genbacev O, Fisher SJ. 1999. Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall. Am J Pathol. 155(1):293–301. doi:https://doi.org/10.1016/S0002-9440(10)65123-1.
- Donovan MJ, Lin MI, Wiegn P, Ringstedt T, Kraemer R, Hahn R, Wang S, Ibañez CF, Rafii S, Hempstead BL. 2000. Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development. 127(21):4531–4540. doi:https://doi.org/10.1242/dev.127.21.4531.
- Elmore S. 2007. Apoptosis: a review of programmed cell death. Toxicol Pathol. 35(4):495–516. doi:https://doi.org/10.1080/01926230701320337.
- Erel CT, Dane B, Calay Z, Kaleli S, Aydinli K. 2001. Apoptosis in the placenta of pregnancies complicated with IUGR. Int J Gynaecol Obstet. 73(3):229–235. doi:https://doi.org/10.1016/S0020-7292(01)00373-3.
- Espinet C, Gonzalo H, Fleitas C, Menal MJ, Egea J. 2015. Oxidative stress and neurodegenerative diseases: a neurotrophic approach. Curr Drug Targets. 16(1):20–30. doi:https://doi.org/10.2174/1389450116666150107153233.
- Forbes K, Westwood M. 2010. Maternal growth factor regulation of human placental development and fetal growth. J Endocrinol. 207(1):1–16. doi:https://doi.org/10.1677/JOE-10-0174.
- Fornes R, Hu M, Maliqueo M, Kokosar M, Benrick A, Carr D, Billig H, Jansson T, Manni L, Stener-Victorin E. 2016. Maternal testosterone and placental function: effect of electroacupuncture on placental expression of angiogenic markers and fetal growth. Mol Cell Endocrinol. 433:1–11. doi:https://doi.org/10.1016/j.mce.2016.05.014.
- Frank P, Barrientos G, Tirado-González I, Cohen M, Moschansky P, Peters EM, Klapp BF, Rose M, Tometten M, Blois SM. 2014. Balanced levels of nerve growth factor are required for normal pregnancy progression. Reproduction. 148(2):179–189. doi:https://doi.org/10.1530/REP-14-0112.
- Freund-Michel V, Frossard N. 2008. The nerve growth factor and its receptors in airway inflammatory diseases. Pharmacol Ther. 117(1):52–76.
- Fujita K, Tatsumi K, Kondoh E, Chigusa Y, Mogami H, Fujii T, Yura S, Kakui K, Konishi I. 2011. Differential expression and the anti-apoptotic effect of human placental neurotrophins and their receptors. Placenta. 32(10):737–744. doi:https://doi.org/10.1016/j.placenta.2011.07.001.
- Gaiday AN, Tussupkaliyev AB, Bermagambetova SK, Zhumagulova SS, Sarsembayeva LK, Dossimbetova MB, Daribay ZZ. 2018. Effect of homocysteine on pregnancy: a systematic review. Chem Biol Interact. 293:70–76. doi:https://doi.org/10.1016/j.cbi.2018.07.021.
- Gauster M, Huppertz B. 2010. The paradox of caspase 8 in human villous trophoblast fusion. Placenta. 31(2):82–88. doi:https://doi.org/10.1016/j.placenta.2009.12.007.
- Germain SJ, Sacks GP, Sooranna SR, Sargent IL, Redman CW. 2007. Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticles. J Immunol. 178(9):5949–5956. doi:https://doi.org/10.4049/jimmunol.178.9.5949.
- Goldstein LD, Reynolds CP, Perez-Polo JR. 1978. Isolation of human nerve growth factor from placental tissue. Neurochem Res. 3(2):175–183. doi:https://doi.org/10.1007/BF00964058.
- Halperin R, Peller S, Rotschild M, Bukovsky I, Schneider D. 2000. Placental apoptosis in normal and abnormal pregnancies. Gynecol Obstet Invest. 50(2):84–87. doi:https://doi.org/10.1159/000010287.
- Harrington AW, Kim JY, Yoon SO. 2002. Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis. J Neurosci. 22(1):156–166. doi:https://doi.org/10.1523/JNEUROSCI.22-01-00156.2002.
- Heazell A, Crocker P. 2008. Live and Let Die - Regulation of villous trophoblast apoptosis in normal and abnormal pregnancies. Placenta. 29(9):772–783. doi:https://doi.org/10.1016/j.placenta.2008.07.003.
- Humphrey RG, Sonnenberg-Hirche C, Smith SD, Hu C, Barton A, Sadovsky Y, Nelson DM. 2008. Epidermal growth factor abrogates hypoxia-induced apoptosis in cultured human trophoblasts through phosphorylation of BAD Serine 112. Endocrinology. 149(5):2131–2137. doi:https://doi.org/10.1210/en.2007-1253.
- Hung TH, Burton GJ. 2006. Hypoxia and reoxygenation: a possible mechanism for placental oxidative stress in preeclampsia. Taiwan J Obstet Gynecol. 45(3):189–200. doi:https://doi.org/10.1016/S1028-4559(09)60224-2.
- Hung TH, Huang SY, Chen SF, Wu CP, Hsieh TT. 2020. Decreased placental apoptosis and autophagy in pregnancies complicated by gestational diabetes with large-for-gestational age fetuses. Placenta. 15(90):27–36. doi:https://doi.org/10.1016/j.placenta.2019.12.003.
- Huppertz B, Kadyrov M, Kingdom JC. 2006. Apoptosis and its role in the trophoblast. Am J Obstet Gynecol. 195(1):29–39. doi:https://doi.org/10.1016/j.ajog.2005.07.039.
- Ishihara N, Matsuo H, Murakoshi H, Laoag-Fernandez JB, Samoto T, Maruo T. 2002. Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am J Obstet Gynecol. 186(1):158–166. doi:https://doi.org/10.1067/mob.2002.119176.
- Jauniaux E, Greenwold N, Hempstock J, Burton GJ. 2003. Comparison of ultrasonographic and Doppler mapping of the intervillous circulation in normal and abnormal early pregnancies. Fertil Steril. 79(1):100–106.
- Kadyrov M, Kingdom JC, Huppertz B. 2006. Divergent trophoblast invasion and apoptosis in placental bed spiral arteries from pregnancies complicated by maternal anemia and early-onset preeclampsia/intrauterine growth restriction. Am J Obstet Gynecol. 194(2):557–563. doi:https://doi.org/10.1016/j.ajog.2005.07.035.
- Kaihola H, Olivier J, Poromaa IS, Åkerud H, Homberg J. 2015. The effect of antenatal depression and selective serotonin reuptake inhibitor treatment on nerve growth factor signaling in human placenta. PLoS ONE. 10(1):1–15. doi:https://doi.org/10.1371/journal.pone.0116459.
- Kamudhamas A, Pang L, Smith SD, Sadovsky Y, Nelson DM. 2004. Homocysteine thiolactone induces apoptosis in cultured human trophoblasts: a mechanism for homocysteine-mediated placental dysfunction? Am J Obstet Gynecol. 191(2):563–571. doi:https://doi.org/10.1016/j.ajog.2004.01.037.
- Kawamura K, Kawamura N, Fukuda J, Kumagai J, Hsueh AJ, Tanaka T. 2007. Regulation of preimplantation embryo development by brain-derived neurotrophic factor. Dev Biol. 311(1):147–158. doi:https://doi.org/10.1016/j.ydbio.2007.08.026.
- Kawamura K, Kawamura N, Sato W, Fukuda J, Kumagai J, Tanaka T. 2009. Brain-derived neurotrophic factor promotes implantation and subsequent placental development by stimulating trophoblast cell growth and survival. Endocrinology. 150(8):3774–3782. doi:https://doi.org/10.1210/en.2009-0213.
- Kerr JF, Wyllie AH, Currie AR. 1972. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 26(4):239–257. doi:https://doi.org/10.1038/bjc.1972.33.
- Kodomari I, Wada E, Nakamura S, Wada K. 2009. Maternal supply of BDNF to mouse fetal brain through the placenta. Neurochem Int. 54(2):95–98. doi:https://doi.org/10.1016/j.neuint.2008.11.005.
- Kolbeck R, Jungbluth S, Barde YA. 1994. Characterisation of neurotrophin dimers and monomers. Eur J Biochem. 225(3):995–1003. doi:https://doi.org/10.1111/j.1432-1033.1994.0995b.x.
- Kuo CY, Shevchuk M, Opfermann J, Guo T, Santoro M, Fisher JP, Kim PC. 2019. Trophoblast-endothelium signaling involves angiogenesis and apoptosis in a dynamic bioprinted placenta model. Biotechnol Bioeng. 116(1):181–192. doi:https://doi.org/10.1002/bit.26850.
- Kwiatkowski S, Dołęgowska B, Kwiatkowska E, Rzepka R, Marczuk N, Loj B, Mikolajek-Bedner W, Torbe A. 2019. Do the physiological aging of the placenta and the changes in angiogenesis marker sFlt-1 and PlGF concentrations predispose patients to late-onset preeclampsia? J Matern Fetal Neonatal Med. 32(1):11–20. doi:https://doi.org/10.1080/14767058.2017.1369517.
- Letai A. 2006. Growth factor withdrawal and apoptosis: the middle game. Mol Cell. 21(6):728–730. doi:https://doi.org/10.1016/j.molcel.2006.03.005.
- Levy R, Nelson DM. 2000. To be, or not to be, that is the question. Apoptosis in human trophoblast. Placenta. 21(1):1–13. doi:https://doi.org/10.1053/plac.1999.0450.
- Longtine MS, Chen B, Odibo AO, Zhong Y, Nelson DM. 2012. Villous trophoblast apoptosis is elevated and restricted to cytotrophoblasts in pregnancies complicated by preeclampsia, IUGR, or preeclampsia with IUGR. Placenta. 33(5):352–359. doi:https://doi.org/10.1016/j.placenta.2012.01.017.
- MacGrogan D, Saint‐André JP, Dicou E. 1992. Expression of nerve growth factor and nerve growth factor receptor genes in human tissues and in prostatic adenocarcinoma cell lines. J Neurochem. 59(4):1381–1391. doi:https://doi.org/10.1111/j.1471-4159.1992.tb08451.x.
- Magee TR, Ross MG, Wedekind L, Desai M, Kjos S, Belkacemi L. 2014. Gestational diabetes mellitus alters apoptotic and inflammatory gene expression of trophobasts from human term placenta. J Diabetes Complications. 28(4):448–459. doi:https://doi.org/10.1016/j.jdiacomp.2014.03.010.
- Mason EF, Rathmell JC. 2011. Cell metabolism: an essential link between cell growth and apoptosis. Biochim Biophys Acta. 1813(4):645–654. doi:https://doi.org/10.1016/j.bbamcr.2010.08.011.
- Mayeur S, Silhol M, Moitrot E, Barbaux S, Breton C, Gabory A, Vaiman D, Dutriez-Casteloot I, Fajardy I, Vambergue A, et al. 2010. Placental BDNF/TrkB signaling system is modulated by fetal growth disturbances in rat and human. Placenta. 31(9):785–791. doi:https://doi.org/10.1016/j.placenta.2010.06.008
- Moll SJ, Jones CJ, Crocker IP, Baker PN, Heazell AE. 2007. Epidermal growth factor rescues trophoblast apoptosis induced by reactive oxygen species. Apoptosis. 12(9):1611–1622. doi:https://doi.org/10.1007/s10495-007-0092-6.
- Norbury CJ, Hickson ID. 2001. Cellular responses to D PMID: 11264462. NA damage. Annu Rev Pharmacol Toxicol. 41:367–401. doi:https://doi.org/10.1146/annurev.pharmtox.41.1.367.
- Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, et al. 2004. Sortilin is essential for proNGF-induced neuronal cell death. Nature. 427(6977):843–848. doi:https://doi.org/10.1038/nature02319
- Perrone L, Paladino S, Mazzone M, Nitsch L, Gulisano M, Zurzolo C. 2005. Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling. Biochem J. 385(Pt 1):233–241. doi:https://doi.org/10.1042/BJ20041155.
- Prince CS, Maloyan A, Myatt L. 2017. Maternal obesity alters brain derived neurotrophic factor (BDNF) signaling in the placenta in a sexually dimorphic manner. Placenta. 49:55–63. doi:https://doi.org/10.1016/j.placenta.2016.11.010.
- Raguema N, Moustadraf S, Bertagnolli M. 2020. Immune and apoptosis mechanisms regulating placental development and vascularization in preeclampsia. Front Physiol. 11:98. doi:https://doi.org/10.3389/fphys.2020.00098.
- Reichardt LF. 2006. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci. 361(1473):1545–1564. doi:https://doi.org/10.1098/rstb.2006.1894.
- Rodríguez M, Couve-Pérez C, San Martín S, Martínez F, Lozano C, Sepúlveda-Martínez A. 2018. Perinatal outcome and placental apoptosis in patients with late-onset pre-eclampsia and abnormal uterine artery Doppler at diagnosis. Ultrasound Obstet Gynecol. 51(6):775–782. doi:https://doi.org/10.1002/uog.17515.
- Rogers ML, Bailey S, Matusica D, Nicholson I, Muyderman H, Pagadala PC, Neet KE, Zola H, Macardle P, Rush RA. 2010. ProNGF mediates death of natural killer cells through activation of the p75NTR-sortilin complex. J Neuroimmunol. 226(1–2):93–103. doi:https://doi.org/10.1016/j.jneuroim.2010.05.040.
- Roux PP, Barker PA. 2002. Neurotrophin signaling through the p75 neurotrophin receptor. Prog Neurobiol. 67(3):203–233. doi:https://doi.org/10.1016/S0301-0082(02)00016-3.
- Rull K, Tomberg K, Kõks S, Männik J, Möls M, Sirotkina M, Värv S, Laan M. 2013. Increased placental expression and maternal serum levels of apoptosis-inducing TRAIL in recurrent miscarriage. Placenta. 34(2):141–148. doi:https://doi.org/10.1016/j.placenta.2012.11.032.
- Sahay AS, Jadhav AT, Sundrani DP, Wagh GN, Joshi SR. 2020. Differential expression of Nerve growth factor (NGF) and Brain derived neurotrophic factor (BDNF) in different regions of normal and preeclampsia placentae. Clin Exp Hypertens. 42(4):360–364. doi:https://doi.org/10.1080/10641963.2019.1665677.
- Sahay AS, Sundrani DP, Wagh GN, Mehendale SS, Joshi SR. 2015. Neurotrophin levels in different regions of the placenta and their association with birth outcome and blood pressure. Placenta. 36(8):938–943. doi:https://doi.org/10.1016/j.placenta.2015.06.006.
- Salavati N, Smies M, Ganzevoort W, Charles AK, Erwich JJ, Plösch T, Gordijn SJ. 2019. The possible role of placental morphometry in the detection of fetal growth restriction. Front Physiol. 9:1884. doi:https://doi.org/10.3389/fphys.2018.01884.
- Scifres CM, Nelson DM. 2009. Intrauterine growth restriction, human placental development and trophoblast cell death. J Physiol. 587(Pt 14):3453–3458. doi:https://doi.org/10.1113/jphysiol.2009.173252.
- Seidah NG, Benjannet S, Pareek S, Savaria D, Hamelin J, Goulet B, Laliberte J, Lazure C, Chrétien M, Murphy RA. 1996. Cellular processing of the nerve growth factor precursor by the mammalian proprotein convertases. Biochem J. 314(Pt 3):951–960. doi:https://doi.org/10.1042/bj3140951.
- Shanab AY, Mysona BA, Matragoon S, El-Remessy AB. 2015. Silencing p75(NTR) prevents proNGF-induced endothelial cell death and development of acellular capillaries in rat retina. Mol Ther Methods Clin Dev. 2:15013. doi:https://doi.org/10.1038/mtm.2015.13.
- Sharp AN, Heazell AE, Crocker IP, Mor G. 2010. Placental apoptosis in health and disease. Am J Reprod Immunol. 64(3):159–169. doi:https://doi.org/10.1111/j.1600-0897.2010.00837.x.
- Shen W, Zhu L, Lee SR, Chung SH, Gillies MC. 2013. Involvement of NT3 and P75(NTR) in photoreceptor degeneration following selective Müller cell ablation. J Neuroinflammation. 10:137. doi:https://doi.org/10.1186/1742-2094-10-137.
- Smith SC, Baker PN, EM S. 1997. Placental apoptosis in normal human pregnancy. Am J Obstet Gynecol. 177(1):57–65. doi:https://doi.org/10.1016/S0002-9378(97)70438-1.
- Song W, Volosin M, Cragnolini AB, Hempstead BL, Friedman WJ. 2010. Pro-NGF induces PTEN via p75NTR to suppress Trk -mediated survival signaling in brain neurons. J Neurosci. 30(46):15608–15615. doi:https://doi.org/10.1523/JNEUROSCI.2581-10.2010.
- Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, Kermani P, Torkin R, Chen ZY, Lee FS, et al. 2005. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci. 25(22):5455–5463. doi:https://doi.org/10.1523/JNEUROSCI.5123-04.2005
- Teng KK, Felice S, Kim T, Hempstead BL. 2010. Understanding proneurotrophin actions: recent advances and challenges. Dev Neurobiol. 70(5):350–359.
- Tometten M, Blois S, Arck PC. 2005. Nerve growth factor in reproductive biology: link between the immune, endocrine and nervous system? Chem Immunol Allergy. 89:135–148.
- Toti P, Ciarmela P, Florio P, Volpi N, Occhini R, Petraglia F. 2006. Human placenta and fetal membranes express nerve growth factor mRNA and protein. J Endocrinol Invest. 29(4):337–341. doi:https://doi.org/10.1007/BF03344105.
- Travaglino A, Raffone A, Saccone G, Migliorini S, Maruotti GM, Esposito G, Mollo A, Martinelli P, Zullo F, D’Armiento M. 2019. Placental morphology, apoptosis, angiogenesis and epithelial mechanisms in early-onset preeclampsia. Eur J Obstet Gynecol Reprod Biol. 234:200–206. doi:https://doi.org/10.1016/j.ejogrb.2018.12.039.
- Urban D, Lorenz J, Meyborg H, Ghosh S, Kintscher U, Kaufmann J, Fleck E, Kappert K, Stawowy P. 2013. Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor. J Biochem. 153(2):197–207. doi:https://doi.org/10.1093/jb/mvs137.
- Whitley GS, Cartwright JE. 2009. Trophoblast-mediated spiral artery remodelling: a role for apoptosis. J Anat. 215(1):21–26. doi:https://doi.org/10.1111/j.1469-7580.2008.01039.x.
- Yang X, Wang Q, Gao Z, Zhou Z, Peng S, Chang WL, Lin HY, Zhang W, Wang H. 2013. Proprotein convertase furin regulates apoptosis and proliferation of granulosa cells in the rat ovary. PLoS One. 8(2):e50479. doi:https://doi.org/10.1371/journal.pone.0050479.
- Yoon SO, Casaccia-Bonnefil P, Carter B, Chao MV. 1998. Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival. J Neurosci. 18(9):3273–3281. doi:https://doi.org/10.1523/JNEUROSCI.18-09-03273.1998.
- Zanin JP, Montroull LE, Volosin M, Friedman WJ. 2019. The p75 neurotrophin receptor facilitates TrkB signaling and function in rat hippocampal neurons. Front Cell Neurosci. 13:485. doi:https://doi.org/10.3389/fncel.2019.00485.
- Zhou X, Jiang Z, Zou Y, Yin Y, Zuo Q, Sun L. 2015. Role of SOCS3 in the Jak/stat3 pathway in the human placenta: different mechanisms for preterm and term labor. Acta Obstet Gynecol Scand. 94(10):1112–1117. doi:https://doi.org/10.1111/aogs.12708.
- Zhou Z, Shen T, Zhang BH, Lv XY, Lin HY, Zhu C, Xue LQ, Wang H. 2009. The proprotein convertase furin in human trophoblast: possible role in promoting trophoblast cell migration and invasion. Placenta. 30(11):929–938. doi:https://doi.org/10.1016/j.placenta.2009.09.003.
- Zhou Z, Zhang Q, Lu X, Wang R, Wang H, Wang YL, Zhu C, Lin HY, Wang H. 2013. The proprotein convertase furin is required for trophoblast syncytialization. Cell Death Dis. 4(4):e593. doi:https://doi.org/10.1038/cddis.2013.106.