A new role under sortilin's belt in cancer

References

• Harding C, Heuser J, Stahl P. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J Cell Biol 1983; 97:329-39; PMID:6309857; http://dx.doi.org/10.1083/jcb.97.2.329
   PubMed Web of Science ®Google Scholar
• Johnstone RM, Adam M, Hammond JR, Orr L, Turbide C. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem 1987; 262:9412-20.
   PubMed Web of Science ®Google Scholar
• Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007; 9:654-9; PMID:17486113; http://dx.doi.org/10.1038/ncb1596
   PubMed Web of Science ®Google Scholar
• Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, et al. Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. J Clin Invest 2014; 124:2136-46; PMID:24743145; http://dx.doi.org/10.1172/JCI70577
   PubMed Web of Science ®Google Scholar
• Lei H, Venkatakrishnan A, Yu S, Kazlauskas A. Protein kinase A-dependent translocation of Hsp90 α impairs endothelial nitric-oxide synthase activity in high glucose and diabetes. J Biol Chem 2007; 282:9364-71; PMID:17202141; http://dx.doi.org/10.1074/jbc.M608985200
   PubMed Web of Science ®Google Scholar
• Chowdhury R, Webber JP, Gurney M, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts. Oncotarget 2014; 6:715-31.
   Web of Science ®Google Scholar
• Ciravolo V, Huber V, Ghedini GC, Venturelli E, Bianchi F, Campiglio M, Morelli D, Villa A, Della Mina P, Menard S, et al. Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy. J Cell Physiol 2012; 227:658-67; PMID:21465472; http://dx.doi.org/10.1002/jcp.22773
   PubMed Web of Science ®Google Scholar
• Singh R, Pochampally R, Watabe K, Lu Z, Mo YY. Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer. Mol Cancer 2014; 13:256; PMID:25428807; http://dx.doi.org/10.1186/1476-4598-13-256
   PubMed Web of Science ®Google Scholar
• Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, et al., VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005; 438:820-7; PMID:16341007; http://dx.doi.org/10.1038/nature04186
   PubMed Web of Science ®Google Scholar
• Hogan MC, Bakeberg JL, Gainullin VG, Irazabal MV, Harmon AJ, Lieske JC, Charlesworth MC, Johnson KL, Madden BJ, Zenka RM, et al. Identification of Biomarkers for PKD1 Using Urinary Exosomes. J Am Soc Nephrol 2014; 26:1661-70.
   PubMed Web of Science ®Google Scholar
• Musante L, Tataruch DE, Holthofer H, Use and isolation of urinary exosomes as biomarkers for diabetic nephropathy. Front Endocrinol (Lausanne) 2014; 5:149; PMID:25309511
   PubMed Web of Science ®Google Scholar
• Yang T, Martin P, Fogarty B, Brown A, Schurman K, Phipps R, Yin VP, Lockman P, Bai S. Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio. Pharm Res 2015; 32:2003-14
   PubMed Web of Science ®Google Scholar
• Wilson CM, Naves T, Saada S, Pinet S, Vincent F, Lalloué F, Jauberteau MO. The implications of sortilin/vps10p domain receptors in neurological and human diseases. CNS Neurol Disord Drug Targets 2014; 13:1354-65; PMID:25345507; http://dx.doi.org/10.2174/1871527313666141023151642
   PubMed Web of Science ®Google Scholar
• Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, et al., Sortilin is essential for proNGF-induced neuronal cell death. Nature 2004; 427:843-8; PMID:14985763; http://dx.doi.org/10.1038/nature02319
   PubMed Web of Science ®Google Scholar
• Mari M, Bujny MV, Zeuschner D, Geerts WJ, Griffith J, Petersen CM, Cullen PJ, Klumperman J, Geuze HJ. SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Traffic 2008; 9:380-93; PMID:18088323; http://dx.doi.org/10.1111/j.1600-0854.2007.00686.x
   PubMed Web of Science ®Google Scholar
• Canuel M, Lefrancois S, Zeng J, Morales CR. AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes. Biochem Biophys Res Commun 2008; 366:724-30; PMID:18078806; http://dx.doi.org/10.1016/j.bbrc.2007.12.015
   PubMed Web of Science ®Google Scholar
• Lefrancois S, Zeng J, Hassan AJ, Canuel M, Morales CR. The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin. EMBO J 2003; 22:6430-7; http://dx.doi.org/10.1093/emboj/cdg629
   PubMed Web of Science ®Google Scholar
• Ni X, Morales CR, The lysosomal trafficking of acid sphingomyelinase is mediated by sortilin and mannose 6-phosphate receptor. Traffic 2006; 7:889-902; PMID:16787399; http://dx.doi.org/10.1111/j.1600-0854.2006.00429.x
   PubMed Web of Science ®Google Scholar
• Mazella J, Zsürger N, Navarro V, Chabry J, Kaghad M, Caput D, Ferrara P, Vita N, Gully D, Maffrand JP, et al. The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. J Biol Chem 1998; 273:26273-6; PMID:9756851; http://dx.doi.org/10.1074/jbc.273.41.26273
   PubMed Web of Science ®Google Scholar
• Munck Petersen C, Nielsen MS, Jacobsen C, Tauris J, Jacobsen L, Gliemann J, Moestrup SK, Madsen P. Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. EMBO J 1999; 18:595-604; PMID:9927419; http://dx.doi.org/10.1093/emboj/18.3.595
   PubMed Web of Science ®Google Scholar
• Navarro V, Martin S, Sarret P, Nielsen MS, Petersen CM, Vincent J, Mazella J. Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin. FEBS Lett, 2001. 495:100-5; PMID:11322955; http://dx.doi.org/10.1016/S0014-5793(01)02367-5
   PubMed Web of Science ®Google Scholar
• Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, Kermani P, Torkin R, Chen ZY, Lee FS, et al. ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci 2005; 25:5455-63; PMID:15930396; http://dx.doi.org/10.1523/JNEUROSCI.5123-04.2005
   PubMed Web of Science ®Google Scholar
• Nilsson SK, Christensen S, Raarup MK, Ryan RO, Nielsen MS, Olivecrona G. Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families. J Biol Chem, 2008. 283:25920-7; PMID:18603531; http://dx.doi.org/10.1074/jbc.M802721200
   PubMed Web of Science ®Google Scholar
• Vaegter CB, Jansen P, Fjorback AW, Glerup S, Skeldal S, Kjolby M, Richner M, Erdmann B, Nyengaard JR, Tessarollo L, et al. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci 2011; 14:54-61.
   PubMed Web of Science ®Google Scholar
• Akil H, Perraud A, Melin C, Jauberteau MO, Mathonnet M. Fine-tuning roles of endogenous brain-derived neurotrophic factor, TrkB and sortilin in colorectal cancer cell survival. PloS One 2011; 6:e25097.
   PubMed Web of Science ®Google Scholar
• Dal Farra C, Sarret P, Navarro V, Botto JM, Mazella J, Vincent JP. Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines. Int J Cancer 2001; 92:503-9.
   PubMed Web of Science ®Google Scholar
• Truzzi F, Marconi A, Lotti R, Dallaglio K, French LE, Hempstead BL, Pincelli C. Neurotrophins and their receptors stimulate melanoma cell proliferation and migration. J Invest Dermatol 2008; 128:2031-40.
   PubMed Web of Science ®Google Scholar
• Giorgi RR, Chile T, Bello AR, Reyes R, Fortes MA, Machado MC, Cescato VA, Musolino NR, Bronstein MD, Giannella-Neto D, et al. Expression of neurotensin and its receptors in pituitary adenomas. J Neuroendocrinol 2008; 20:1052-7.
   PubMed Web of Science ®Google Scholar
• Xiong J, Zhou L, Yang M, Lim Y, Zhu YH, Fu DL, Li ZW, Zhong JH, Xiao ZC, Zhou XF. ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro. Neuro Oncol 2013; 15:990-1007.
   PubMed Web of Science ®Google Scholar
• Navarro V, Vincent JP, Mazella J. Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line. Biochem Biophys Res Commun 2002; 298:760-4.
   PubMed Web of Science ®Google Scholar
• Martin S, Navarro V, Vincent JP, Mazella J. Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line. Gastroenterology 2002; 123:1135-43.
   PubMed Web of Science ®Google Scholar
• Massa F, Devader C, Beraud-Dufour S, Brau F, Coppola T, Mazella J. Focal adhesion kinase dependent activation of the PI3 kinase pathway by the functional soluble form of neurotensin receptor-3 in HT29 cells. Int J Biochem Cell Biol 2013; 45:952-9.
   PubMed Web of Science ®Google Scholar
• Liu P, Cheng H, Roberts TM, Zhao JJ. Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov 2009; 8:627-44.
   PubMed Web of Science ®Google Scholar
• Schecterson LC, Bothwell M. Neurotrophin receptors: Old friends with new partners. Dev Neurobiol 2010; 70:332-8.
   PubMed Web of Science ®Google Scholar
• Skeldal S, Matusica D, Nykjaer A, Coulson EJ. Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR). BioEssays 2011; 33:614-25.
   PubMed Web of Science ®Google Scholar
• Reichardt LF. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 2006; 361:1545-64.
   PubMed Web of Science ®Google Scholar
• Volosin M, Song W, Almeida RD, Kaplan DR, Hempstead BL, Friedman WJ. Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. J Neurosci 2006; 26:7756-66.
   PubMed Web of Science ®Google Scholar
• Harrington AW, Leiner B, Blechschmitt C, Arevalo JC, Lee R, Morl K, Meyer M, Hempstead BL, Yoon SO, Giehl KM. Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. Proc Natl Acad Sci U S A 2004; 101:6226-30.
   Google Scholar
• Wilson CM, Naves T, Vincent F, Melloni B, Bonnaud F, Lalloue F, Jauberteau MO. Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors. J Cell Sci 2014; 127:3983-97.
   PubMed Web of Science ®Google Scholar
• Tamai K, Tanaka N, Nakano T, Kakazu E, Kondo Y, Inoue J, Shiina M, Fukushima K, Hoshino T, Sano K, et al. Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein. Biochem Biophys Res Commun 2010; 399:384-90.
   PubMed Web of Science ®Google Scholar
• Colombo M, Moita C, van Niel G, Kowal J, Vigneron J, Benaroch P, Manel N, Moita LF, Thery C, Raposo G. Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci 2013; 126:5553-65.
   PubMed Web of Science ®Google Scholar