560
Views
42
CrossRef citations to date
0
Altmetric
Original Articles

Simultaneous determination of 10 mycotoxins in grain by ultra-high-performance liquid chromatography–tandem mass spectrometry using 13C15-deoxynivalenol as internal standard

, , , &
Pages 1701-1713 | Received 17 Apr 2010, Accepted 17 Aug 2010, Published online: 11 Oct 2010

References

  • Bascaran , V , de Rojas , AH , Choucino , P and Delgado , T . 2007 . Analysis of ochratoxin A in milk after direct immunoaffinity column clean-up by high-performance liquid chromatography with fluorescence detection . J Chromatogr A , 1167 ( 1 ) : 95 – 101 .
  • Berthiller , F , Schuhmacher , R , Buttinger , G and Krska , R . 2005 . Rapid simultaneous determination of major type A- and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography–tandem mass spectrometry . J Chromatogr A , 1062 ( 2 ) : 209 – 216 .
  • Bogialli , S , Curini , R , Di Corcia , A , Nazzari , M and Samperi , R . 2003 . A liquid chromatography-mass spectrometry assay for analyzing sulfonamide antibacterials in cattle and fish muscle tissues . Anal Chem , 75 ( 8 ) : 1798 – 1804 .
  • Bottalico , A . 1998 . Fusarium disease of cereals: species complex and related mycotoxin profiles in Europe . J Plant Pathol , 80 ( 2 ) : 85 – 103 .
  • Briones-Reyes , D , Gomez-Martinez , L and Cueva-Rolon , R . 2007 . Zearalenone contamination in corn for human consumption in the state of Tlaxcala, Mexico . Food Chem , 100 ( 2 ) : 693 – 698 .
  • Castillo , MA , Montes , R , Navarro , A , Segarra , R , Cuesta , G and Hernandez , E . 2008 . Occurrence of deoxynivalenol and nivalenol in Spanish corn-based food products . J Food Compos Anal , 21 ( 5 ) : 423 – 427 .
  • Cavaliere , C , D'Ascenzo , G , Foglia , P , Pastorini , E , Samperi , R and Lagana , A . 2005 . Determination of type B trichothecenes and macrocyclic lactone mycotoxins in field contaminated maize . Food Chem , 92 ( 3 ) : 559 – 568 .
  • Chinese Commission. 2005. Commission Regulation (GB) No. 2761/2005 of 1 October 2005 amending Regulations (GB) No. 9676/2003, No. 2761/1981, No. 16329/1996 and No. 14974/2003 as maximum levels of mycotoxins in foods. GuoBiao. L 53:1–2
  • Cohen , H and Lapointe , M . 1982 . Capillary gas–liquid chromatographic determination of vomitoxin in cereal grains . J Assoc Off Anal Chem , 65 ( 6 ) : 1429 – 1434 .
  • Cunha , SC , Faria , MA and Fernandes , JO . 2009 . Determination of patulin in apple and quince products by GC–MS using 13C5-7 patulin as internal standard . Food Chem , 115 ( 1 ) : 352 – 359 .
  • Di Mavungu , DJ , Monbaliu , S , Scippo , ML , Maghuin-Rogister , G , Schneider , YJ , Larondelle , Y , Callebaut , A , Robbens , J , Van Peteghem , C and De Saeger , S . 2009 . LC-MS/MS multi-analyte method for mycotoxin determination in food supplements . Food Addit Contam , 26 ( 6 ) : 885 – 895 .
  • D'Mello , JPF , Placinta , CM and Macdonald , AMC . 1999 . Fusarium mycotoxins: a review of global implications for animal health, welfare and productivity . Anim Feed Sci Technol , 80 ( 3/4 ) : 183 – 205 .
  • Eppley , RM , Trucksess , MW , Nesheim , S , Thorpe , CW and Pohland , AE . 1986 . Thin-Layer chromatographic method for determination of deoxynivalenol in wheat . Collaborative study. J Assoc Off Anal Chem , 69 ( 1 ) : 37 – 40 .
  • European Commission. 2002. Commission Regulation No. 472/2002, 2002. Off J Eur Union. L75:18–20
  • European Commission. 2005. Commission Regulation (EC) No. 856/2005 of 6 June 2005 amending Regulation (EC) No. 466/2001 as regards Fusarium toxins (Text with EEA relevance). Off J Eur Union. L143:3–8
  • European Commission. 2007. Commission Regulation (EC) No. 1126/2007 of 28 September 2007 amending Regulation (EC) No. 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products. Off J Eur Union. L255:14–17
  • Gilbert , J , Sharman , M , Patel , S , Boenke , A and Wagstaffe , PJ . 1992 . Deoxynivalenol in wheat and maize flour reference materials . 2. Preparation and certification. Food Addit Contam , 9 ( 2 ) : 119 – 135 .
  • González-Osnaya , L , Soriano , JM , Moltó , JC and Maňes , J . 2008 . Simple liquid chromatography assay for analyzing ochratoxin A in bovine milk . Food Chem , 108 ( 1 ) : 272 – 276 .
  • Grabarkiewicz-Szczesna , J , Kostecki , M , Golinski , P and Kiecana , I . 2001 . Fusariotoxins in kernels of winter wheat cultivars field samples collected during (1993) in Poland . Nahrung-Food , 45 ( 1 ) : 28 – 30 .
  • Häubl , G , Berthiller , F , Krska , R and Schuhmacher , R . 2006 . Suitability of a fully 13C isotope labeled internal standard for the determination of the mycotoxin deoxynivalenol by LC-MS/MS without clean up . Anal Bioanal Chem , 384 ( 3 ) : 692 – 696 .
  • Kabak , B . 2009 . Ochratoxin A in cereal-derived products in Turkey: occurrence and exposure assessment . Food Chem Toxicol , 47 ( 2 ) : 348 – 352 .
  • Kebarle , P and Tang , L . 1993 . From ions in solution to ions in the gas phase – the mechanism of electrospray mass spectrometry . Anal Chem , 65 ( 22 ) : 972A – 986A .
  • Klötzel , M , Gutsche , B , Lauber , U and Humpf , HU . 2005 . Determination of 12 type A and B trichothecenes in cereals by liquid chromatography-electrospray ionization tandem mass spectrometry . J Agric Food Chem , 53 ( 23 ) : 8904 – 8910 .
  • Klötzel , M , Lauber , U and Humpf , HU . 2006 . A new solid phase extraction clean-up method for the determination of 12 type A and B trichothecenes in cereals and cereal-based food by LC-MS/MS . Mol Nutr Food Res , 50 ( 3 ) : 261 – 269 .
  • Krska , R and Josephs , R . 2001 . The state-of-the-art in the analysis of estrogenic mycotoxins in cereals . Fresenius J Anal Chem , 369 ( 6 ) : 469 – 476 .
  • Krska , R , Baumgartner , S and Josephs , R . 2001 . The state-of-the-art in the analysis of type-A and -B trichothecene mycotoxins in cereals . Fresenius J Anal Chem , 371 ( 3 ) : 285 – 299 .
  • Kuiper-Goodman , T . 1995 . Mycotoxins: risk assessment and legislation . Toxicol Lett , 82–83 ( 7 ) : 853 – 859 .
  • Maragos , CM and Appell , M . 2007 . Capillary electrophoresis of the mycotoxin zearalenone using cyclodextrin-enhanced fluorescence . J Chromatogr A , 1143 ( 1–2 ) : 252 – 257 .
  • Mateo , JJ , Mateo , R , Hinojo , MJ , Llorens , A and Jimenez , M . 2002 . Liquid chromatographic determination of toxigenic secondary metabolites produced by Fusarium strains . J Chromatogr A , 955 ( 2 ) : 245 – 256 .
  • Mubatanhema , W , Moss , MO , Frank , MJ and Wilson , DM . 1999 . Prevalence of Fusarium species of the Liseola section on Zimbabwean corn and their ability to produce the mycotoxins zearalenone, moniliformin and fumonisin B1 . Mycopathologia , 148 ( 3 ) : 157 – 163 .
  • Omurtag , GZ and Yazicioglu , D . 2001 . Occurrence of T-2 toxin in processed cereals and pulses in Turkey determined by HPLC and TLC . Food Addit Contam , 18 ( 9 ) : 844 – 849 .
  • Razzazi-Fazeli , E , Rabus , B , Cecon , B and Bohm , J . 2002 . Simultaneous quantification of A-trichothecene mycotoxins in grains using liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry . J Chromatogr A , 968 ( 1/2 ) : 129 – 142 .
  • Ren , Y , Zhang , Y , Shao , S , Cai , Z , Feng , L , Pan , H and Wang , Z . 2007 . Simultaneous determination of multi-component mycotoxin contaminants in foods and feeds by ultra-performance liquid chromatography tandem mass spectrometry . J Chromatogr A , 1143 ( 1/2 ) : 48 – 64 .
  • Schollenberger , M , Lauber , U , Jara , HT , Suchy , S , Drochner , W and Muller , HM . 1998 . Determination of eight trichothecenes by gas chromatography-mass spectrometry after sample clean-up by a two-stage solid-phase extraction . J Chromatogr A , 815 ( 1 ) : 123 – 132 .
  • Solovey , MM , Somoza , C , Cano , G , Pacin , A and Resnik , S . 1999 . A survey of fumonisins, deoxynivalenol, zearalenone and aflatoxins contamination in corn-based food products in Argentina . Food Addit Contam , 16 ( 8 ) : 325 – 329 .
  • Spanjer , MC , Rensen , PM and Scholten , JM . 2008 . LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs . Food Addit Contam , 25 ( 4 ) : 472 – 489 .
  • Sulyok , M , Berthiller , F , Krska , R and Schuhmacher , R . 2006 . Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize . Rapid Commun Mass Spectrom , 20 ( 18 ) : 2649 – 2659 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.