660
Views
65
CrossRef citations to date
0
Altmetric
Original Articles

Characterisation of aflatoxin and deoxynivalenol exposure among pregnant Egyptian women

, , , , , , , , , & show all
Pages 962-971 | Received 11 Jul 2011, Accepted 11 Jan 2012, Published online: 01 Mar 2012

References

  • Allen , SJ , Wild , CP , Wheeler , JG , Riley , EM , Montesano , R , Bennett , S , Whittle , HC , Hall , AJ and Greenwood , BM . 1992 . Aflatoxin exposure, malaria and hepatitis B infection in rural Gambian children . Trans R Soc Trop Med Hyg , 86 : 426 – 430 .
  • Bennett , JW and Klich , M . 2003 . Mycotoxins . Clin Microbiol Rev , 16 : 497 – 516 .
  • Chapot , B and Wild , CP . 1991 . “ ELISA for quantification of aflatoxin–albumin adducts and their application to human exposure assessment ” . In Techniques in diagnostic pathology , Edited by: Warthol , M , van Velzer , D and Bullock , GR . 135 – 155 . London : Academic Press .
  • Collins , TF , Sprando , RL , Black , TN , Olejnik , N , Eppley , RM , Hines , FA , Rorie , J and Ruggles , DI . 2006 . Effects of deoxynivalenol (DON, vomitoxin) on in utero development in rats . Food Chem Toxicol , 44 : 747 – 757 .
  • Côté , LM , Nicoletti , J , Swanson , SJ and Buck , W . 1986 . Production of deepoxydeoxynivalenol (DOM-1), a metabolite of deoxynivalenol, by in vitro rumen incubation . J Agric Food Chem , 34 : 458 – 460 .
  • Council for Agricultural Science and Technology (CAST) . 2003 . Mycotoxins: risks in plant, animal and human systems. Task Force Report No. 139 , Ames , IA : CAST .
  • Dänicke , S , Brüssow , KP , Goyarts , T , Valenta , H , Ueberschär , KH and Tiemann , U . 2007 . On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from the sow to the full-term piglet during the last third of gestation . Food Chem Toxicol , 45 : 1565 – 1574 .
  • Devegowda , G , Raju , MVLN and Swang , HVLN . 1998 . Mycotoxins: novel solutions for their counteraction . Feedstuffs , 70 : 12 – 15 .
  • Egal , S , Hounsa , A , Gong , YY , Turner , PC , Wild , CP , Hall , AJ , Hell , K and Cardwell , KF . 2005 . Dietary exposure to aflatoxin from maize and groundnut in young children from Benin and Togo, West Africa . Int J Food Microbiol , 104 : 215 – 224 .
  • El-Nezami , H , Kankaanpää , P , Salminen , S and Ahokas , J . 1998 . Ability of dairy strains of lactic acid bacteria to bind a common food carcinogen, aflatoxin B1 . Food Chem Toxicol , 36 : 321 – 326 .
  • El-Nezami , HS , Chrevatidis , A , Auriola , S , Salminen , S and Mykkänen , H . 2002 . Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium . Food Addit Contam , 19 : 680 – 686 .
  • European Food Safety Authority (EFSA) . 2004 . Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to deoxynivalenol (DON) as undesirable substance in animal feed . EFSA J , 73 : 1 – 42 .
  • Gan , LS , Skipper , PL , Peng , XC , Groopman , JD , Chen , JS , Wogan , GN and Tannenbaum , SR . 1988 . Serum albumin adducts in the molecular epidemiology of aflatoxin carcinogenesis: Correlation with aflatoxin B1 intake and urinary excretion of aflatoxin M1 . Carcinogenesis , 9 : 1323 – 1325 .
  • Gong , Y , Hounsa , A , Egal , S , Turner , PC , Sutcliffe , AE , Hall , AJ , Cardwell , K and Wild , CP . 2004 . Postweaning exposure to aflatoxin results in impaired child growth: a longitudinal study in Benin, West Africa . Environ Health Perspect , 112 : 1334 – 1338 .
  • Gong , YY , Cardwell , K , Hounsa , A , Egal , S , Turner , PC , Hall , AJ and Wild , CP . 2002 . Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: Cross sectional study . Br Med J , 325 : 20 – 21 .
  • Gong , YY , Turner , PC , Hall , AJ and Wild , CP . 2008 . “ Aflatoxin exposure and impaired child growth in West Africa: an unexplored international public health burden? ” . In Mycotoxins. Detection methods, management, public health and agricultural trade , Edited by: Leslie , JF , Bandyopadhyay , R and Visconti , A . 53 – 65 . Wallingford , , UK : CABI .
  • Goyarts , T , Danicke , S , Brussow , KP , Valenta , H , Ueberschar , KH and Tiemann , U . 2007 . On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from sows to their fetuses during days 35–70 of gestation . Toxicol Lett , 171 : 38 – 49 .
  • Groopman , JD . 1994 . “ Molecular dosimetry methods for assessing human aflatoxin exposures ” . In The toxicology of aflatoxins: human health, veterinary and agricultural significance , Edited by: Eaton , DL and Groopman , JD . 259 – 280 . San Diego , CA : Academic Press .
  • Groopman , JD , DeMatos , P , Egner , PA , Love-Hunt , A and Kensler , TW . 1992 . Molecular dosimetry of urinary aflatoxin-N7-guanine and serum aflatoxin–albumin adducts predicts chemoprotection by 1,2-dithiole-3-thione in rats . Carcinogenesis , 13 : 101 – 106 .
  • Groopman , JD , Hall , AJ , Whittle , H , Hudson , GJ , Wogan , GN , Montesano , R and Wild , CP . 1992 . Molecular dosimetry of aflatoxin-N7-guanine in human urine obtained in the Gambia, West Africa . Cancer Epidemiol Biomarkers Prev , 1 : 221 – 227 .
  • Groopman , JD , Johnson , D and Kensler , TW . 2005 . Aflatoxin and hepatitis B virus biomarkers: a paradigm for complex environmental exposures and cancer risk . Cancer Biomark , 1 : 5 – 14 .
  • Hassan , AM , Sheashaa , HA , Abdel Fatah , MF , Ibrahim , AZ and Gaber , OA . 2006 . Does aflatoxin as an environmental mycotoxin adversely affect the renal and hepatic functions of Egyptian lactating mothers and their infants? A preliminary report . Int Urol Nephrol , 38 : 339 – 342 .
  • Hatem , NL , Hassab , HM , Abd Al-Rahman , EM , El-Deeb , SA and El-Sayed Ahmed , RL . 2005 . Prevalence of aflatoxins in blood and urine of Egyptian infants with protein-energy malnutrition . Food Nutr Bull , 26 : 49 – 56 .
  • International Agency for Research on Cancer (IARC) . 1993 . Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins . IARC Monogr Eval Carsinog Risk Hum , 56 : 245 – 395 .
  • International Agency for Research on Cancer (IARC) . 2002 . Some traditional herbal medicines, some mycotoxins, naphthalene and styrene . IARC Monogr Eval Carsinog Risk Hum , 82 : 171 – 293 .
  • Kollarczik , B , Gareis , M and Hanelt , M . 1994 . In vitro transformation of the Fusarium mycotoxins deoxynivalenol and zearalenone by the normal gut microflora of pigs . Nat Toxins , 2 : 105 – 110 .
  • Maxwell , SM . 1998 . Investigations into the presence of aflatoxins in human body fluids and tissues in relation to child health in the tropics . Ann Trop Paediatr , 18 : S41 – S46 .
  • Murphy , PA , Hendrich , S , Landgren , C and Bryant , CM . 2006 . Food mycotoxins: an update . J Food Sci , 71 : 51 – 65 .
  • Nielsen , JK , Vikström , AC , Turner , P and Knudsen , LE . 2011 . Deoxynivalenol transport across the human placental barrier . Food Chem Toxicol , 49 : 2046 – 2052 .
  • Pestka , JJ and Smolinski , AT . 2005 . Deoxynivalenol: toxicology and potential effects on humans . J Toxicol Environ Health B Crit Rev , 8 : 39 – 69 .
  • Polychronaki , N , Turner , PC , Mykkänen , H , Gong , Y , Amra , H , Abdel-Wahhab , M and El-Nezami , H . 2006 . Determinants of aflatoxin M1 in breast milk in a selected group of Egyptian mothers . Food Addit Contam , 23 : 700 – 708 .
  • Polychronaki , N , West , RM , Turner , PC , Amra , H , Abdel-Wahhab , M , Mykkänen , H and El-Nezami , H . 2007 . A longitudinal assessment of aflatoxin M1 excretion in breast milk of selected Egyptian mothers . Food Chem Toxicol , 45 : 1210 – 1215 .
  • Polychronaki , N , Wild , CP , Mykkänen , H , Amra , H , Abdel-Wahhab , M , Sylla , A , Diallo , M , El-Nezami , H and Turner , PC . 2008 . Urinary biomarkers of aflatoxin exposure in young children from Egypt and Guinea . Food Chem Toxicol , 46 : 519 – 526 .
  • Rotter , BA , Prelusky , DB and Pestka , JJ . 1996 . Toxicology of deoxynivalenol (vomitoxin) . J Toxicol Environ Health , 48 : 1 – 34 .
  • Shephard , GS . 2003 . Aflatoxin and food safety: recent African perspectives . J Toxicol Toxin Rev , 22 : 267 – 286 .
  • Shreeve , BJ , Patterson , DS and Roberts , BA . 1979 . The ‘carry-over’ of aflatoxin, ochratoxin and zearalenone from naturally contaminated feed to tissues, urine and milk of dairy cows . Food Cosmet Toxicol , 17 : 151 – 152 .
  • Shuaib , FM , Jolly , PE , Ehiri , JE , Yatich , N , Jiang , Y , Funkhouser , E Person , SD . 2010 . Association between birth outcomes and aflatoxin B1 biomarker blood levels in pregnant women in Kumasi, Ghana . Trop Med Int Health , 15 : 160 – 167 .
  • Speijers , GJA and Speijers , MHM . 2004 . Combined toxic effects of mycotoxins . Toxicol Lett , 153 : 91 – 98 .
  • Turner , PC , Burley , VJ , Rothwell , JA , White , KL , Cade , JE and Wild , CP . 2008a . Deoxynivalenol: rationale for development and application of a urinary biomarker . Food Addit Contam A , 25 : 864 – 871 .
  • Turner , PC , Burley , VJ , Rothwell , JA , White , KL , Cade , JE and Wild , CP . 2008b . Dietary wheat reduction decreases the level of urinary deoxynivalenol in UK adults . J Expo Sci Environ Epidemiol , 18 : 392 – 399 .
  • Turner , PC , Collinson , AC , Cheung , YB , Gong , Y , Hall , AJ , Prentice , AM and Wild , CP . 2007 . Aflatoxin exposure in utero causes growth faltering in Gambian infants . Int J Epidemiol , 36 : 1119 – 1125 .
  • Turner , PC , Hopton , RP , Lecluse , Y , White , KL , Fisher , J and Lebailly , P . 2010 . Determinants of urinary deoxynivalenol and de-epoxy deoxynivalenol in male farmers from Normandy, France . J Agric Food Chem , 58 : 5206 – 5212 .
  • Turner , PC , Loffredo , C , Kafrawy , SE , Ezzat , S , Eissa , SA , Daly , ME , Nada , O and Abdel-Hamid , M . 2008 . Pilot survey of aflatoxin–albumin adducts in sera from Egypt . Food Addit Contam A , 25 : 583 – 587 .
  • Turner , PC , Moore , SE , Hall , AJ , Prentice , AM and Wild , CP . 2003 . Modification of immune function through exposure to dietary aflatoxin in Gambian children . Environ Health Perspect , 111 : 217 – 220 .
  • Turner , PC , Rothwell , JA , White , KL , Gong , Y , Cade , JE and Wild , CP . 2008 . Urinary deoxynivalenol is correlated with cereal intake in individuals from the United Kingdom . Environ Health Perspect , 116 : 21 – 25 .
  • Turner , PC , Sylla , A , Gong , YY , Diallo , MS , Sutcliffe , AE , Hall , AJ and Wild , CP . 2005 . Reduction in exposure to carcinogenic aflatoxins by postharvest intervention measures in West Africa: a community-based intervention study . Lancet , 365 : 1950 – 1956 .
  • Turner , PC , Taylor , EF , White , KL , Cade , JE and Wild , CP . 2009 . A comparison of 24 h urinary deoxynivalenol with recent v . average cereal consumption for UK adults. Br J Nutr , 102 : 1276 – 1279 .
  • Turner , PC , van der Westhuizen , L and Da Costa , AN . 2011 . “ Biomarkers of exposure: mycotoxins – aflatoxin, deoxynivalenol and fumonisins ” . In Biomarkers and human biomonitoring , Edited by: Knudsen , LE and Merlo , DF . 50 – 86 . Cambridge , , UK : Royal Society of Chemistry .
  • Turner , PC , White , KL , Burley , VJ , Hopton , RP , Rajendram , A , Fisher , J , Cade , JE and Wild , CP . 2010 . A comparison of deoxynivalenol intake and urinary deoxynivalenol in UK adults . Biomarkers , 15 : 553 – 562 .
  • Wang , P , Afriyie-Gyawu , E , Tang , Y , Johnson , NM , Xu , L , Tang , L Huebner , HJ . 2008 . NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis: II. Reduction in biomarkers of aflatoxin exposure in blood and urine . Food Addit Contam A , 25 : 622 – 634 .
  • Wild , CP and Gong , YY . 2010 . Mycotoxins and human disease: a largely ignored global health issue . Carcinogenesis , 31 : 71 – 82 .
  • Wild , CP , Rasheed , FN , Jawla , MF , Hall , AJ , Jansen , LA and Montesano , R . 1991 . In-utero exposure to aflatoxin in West Africa . The Lancet , 337 : 1602
  • Wild , CP , Yin , F , Turner , PC , Chemin , I , Chapot , B , Mendy , M , Whittle , H , Kirk , GD and Hall , AJ . 2000 . Environmental and genetic determinants of aflatoxin–albumin adducts in The Gambia . Int J Cancer , 86 : 1 – 7 .
  • Yoshizawa , T , Cote , LM , Swanson , SP and Buck , WB . 1986 . Confirmation of DOM-1, a de-epoxidation metabolite of deoxynivalenol, in biological fluids of lactating cows . Agric Biol Chem , 50 : 227 – 229 .
  • Zarba , A , Wild , CP , Hall , AJ , Montesano , R , Hudson , GJ and Groopman , JD . 1992 . Aflatoxin M1 in human breast milk from The Gambia, West Africa, quantified by combined monoclonal antibody immunoaffinity chromatography and HPLC . Carcinogenesis , 13 : 891 – 894 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.