Determination of prednisolone metabolites in beef cattle

References

• Antignac JP, Le Bizec B, Monteau F, Poulain F, Andre F. 2001. Multi-residue extraction–purification procedure for corticosteroids in biological samples for efficient control of their misuse in livestock production. J Chromatogr B. 757:11–19.
   PubMed Web of Science ®Google Scholar
• Arioli F, Fidani M, Casati A, Fracchiolla ML, Pompa G. 2010. Investigation on possible transformations of cortisol, cortisone and cortisol glucuronide in bovine faecal matter using liquid chromatography–mass spectrometry. Steroids. 75:350–354.
   PubMed Web of Science ®Google Scholar
• Blokland MH, Van Rossum HJ, Sterk SS, Van Ginkel LA, Stephany RW. 2007. Development of a method which discriminates between endogenous and exogenous beta-boldenone. Anal Chim Acta. 586:147–153.
   PubMed Web of Science ®Google Scholar
• Cannizzo FT, Capra P, Divari S, Ciccotelli V, Biolatti B, Vincenti M. 2011. Effects of low-dose dexamethasone and prednisolone long term administration in beef calf: chemical and morphological investigation. Anal Chim Acta. 700:95–104.
   PubMed Web of Science ®Google Scholar
• Circular of Ministry of Health 2012. Department of Public and Veterinary Health about the opinion of the Consiglio Superiore di Sanità, Sezione IV, 22 May 2012.
   Google Scholar
• Courtheyn D, Le Bizec B, Brambilla G, De Brabander HF, Cobbaert E, Van de Wiele M, Vercammen J, De Wasch K. 2002. Recent developments in the use and abuse of growth promoters. Anal Chim Acta. 473:21–82.
   Web of Science ®Google Scholar
• De Brabander HF, Le Bizec B, Pinel G, Antignac JP, Verheyden K, Mortier V, Courtheyn D, Noppe H. 2007. Past, present and future of mass spectrometry in the analysis of residues of banned substances in meat-producing animals. J Mass Spectrom. 42:983–998.
   PubMed Web of Science ®Google Scholar
• Destrez B, Pinel G, Monteau F, Lafont R, Le Bizec B. 2009. Detection and identification of 20-hydroxyecdysone metabolites in calf urine by liquid chromatography-high resolution or tandem mass spectrometry measurements and establishment of their kinetics of elimination after 20-hydroxyecdysone administration. Anal Chim Acta. 637:178–184.
   PubMed Web of Science ®Google Scholar
• Deventer K, Delbeke FT. 2003. Validation of a screening method for corticosteroids in doping analysis by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 17:2107–2114.
   PubMed Web of Science ®Google Scholar
• Divari S, Cannizzo FT, Uslenghi F, Pregel P, Mulasso C, Spada F, De Maria R, Biolatti B. 2011. Corticosteroid hormone receptors and prereceptors as new biomarkers of the illegal use of glucocorticoids in meat production. J Agric Food Chem. 59:2120–2125.
   PubMed Web of Science ®Google Scholar
• EMEA-Committee for Veterinary Medicinal Products. 1999. Prednisolone (as free alcohol). Available from: http://www.eudra.org/emea.html
   Google Scholar
• European Commission. 2002. 2002/657/EC: Commission Decision of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Comm. L221:8–36.
   Google Scholar
• Ferranti C, Delli Quadri F, Palleschi L, Marchiafava C, Pezzolato M, Bozzetta E, Caramelli M, Draisci R. 2011. Studies on the presence of natural and synthetic corticosteroids in bovine urine. Steroids. 76:616–625.
   PubMed Web of Science ®Google Scholar
• Garg V, Jusko WJ. 1991. Simultaneous analysis of prednisone, prednisolone and their major hydroxylated metabolites in urine by high-performance liquid chromatography. J Chromatogr. 567:39–47.
   PubMed Web of Science ®Google Scholar
• Gray CH, Green MAS, Holness NJ, Lunnon JB. 1956. Urinary metabolic products of prednisone and prednisolone. J Endocrinol. 14:146–154.
   PubMed Web of Science ®Google Scholar
• Leporati M, Capra P, Brizio P, Ciccotelli V, Abete MC, Vincenti M. 2012. Fit-for-purpose in veterinary drug residue analysis: development and validation of an LC-MS/MS method for the screening of thirty illicit drugs in bovine urine. J Sep Sci. 35:400–409.
   PubMed Web of Science ®Google Scholar
• Maser E. 1995. Xenobiotic carbonyl reduction and physiological steroid oxidoreduction – the pluripotency of several hydroxysteroid dehydrogenases. Biochem Pharmacol. 49: 421–440.
   PubMed Web of Science ®Google Scholar
• Nebbia C, Urbani A, Carletti M, Gardini G, Balbo A, Bertarelli D, Girolami F. 2010. Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters. Vet J. 189:34–42.
   PubMed Web of Science ®Google Scholar
• Pinel G, Rambaud L, Cacciatore G, Bergwerff CE, Nielen M, Le Bizec B. 2008. Elimination kinetic of 17b-estradiol 3 benzoate and 17b-nandrolone laureate ester metabolites in calves’ urine. J Steroid Biochem Mol Biol. 110:30–38.
   PubMed Web of Science ®Google Scholar
• Pompa G, Arioli F, Casati A, Fidani M, Bertocchi L, Dusi G. 2011. Investigation of the origin of prednisolone in cow urine. Steroids. 76:104–110.
   PubMed Web of Science ®Google Scholar
• Savu SR, Silvestro L, Haag A, Sorgel F. 1996. A confirmatory HPLC-MS/MS method for ten synthetic corticosteroids in bovine urines. J Mass Spectrom. 31:1351–1363.
   PubMed Web of Science ®Google Scholar
• Stolker AAM, Brinkman U. 2005. Analytical strategies for residue analysis of veterinary drugs and growth-promoting agents in food-producing animals-a review. J Chromatogr A. 1067:15–53.
   PubMed Web of Science ®Google Scholar
• Vermeulen A, Caspi E. 1959. Metabolism of 1-Dehydrosteroids in man. J Biol Chem. 234:2295–2297.
   PubMed Web of Science ®Google Scholar
• Vincenti M, Leporati M, Capra P, Gatto S, Attucci A, Barbarino G, Nebbia C. 2012. A field survey on the presence of prednisolone and prednisone in urine samples from untreated cows. Food Addit Contam. 29:1893–1900. doi:10.1080/19440049.2012.719645
   PubMed Web of Science ®Google Scholar