Advanced search
Publication Cover
Food Additives & Contaminants: Part A Volume 30, 2013 - Issue 6: Residues of veterinary medicines in food – recent developments in detection and determination of residues: Proceedings of EuroResidues VII held in the Netherlands, May 14–16th 2012
Submit an article Journal homepage
490
Views
9
CrossRef citations to date
0
Altmetric
Original Articles

Rapid method for the determination of metamizole residues in bovine muscle by LC-MS/MS

Piotr JedziniakDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, PolandCorrespondence[email protected]
,
Konrad PietrukDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, Poland
,
Edyta ŚledzińskaDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, Poland
,
Małgorzata OlejnikDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, Poland
,
Teresa Szprengier-JuszkiewiczDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, Poland
&
Jan ŻmudzkiDepartment of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, Poland
Pages 977-982 | Received 15 Sep 2012, Accepted 16 Mar 2013, Published online: 22 May 2013

References

  • Andrade SE, Martinez C, Walker AM. 1998. Comparative safety evaluation of non-narcotic analgesics. J Clin Epidemol. 51:1357–1365.
  • European Commision. 2002. Commission decision of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Comm L. 221:8–36.
  • European Commision. 2009. Commission Regulation 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Off J Eur Union L. 15:1–71.
  • European Medicine Agency. 1999. Metamizole – summary report. Available from: EMEA/MRL/529/98-FINAL-CORRIGENDUM, http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500015052.pdf
  • European Union Reference Laboratory for Residues of Veterinary Drugs. 2001. MAA_001: confirmatory method for determination of metamizole metabolites in liver using HPLC with DAD detection, Version No. 01 of June 2001. Available from: https://fis-vl.bund.de/Members/irc/fis-vl/crl/library?l=/10_service/analytical_methods/pdfs/maa_001_v01_publicpdf/_EN_1.0_&a=d
  • Ibáñez M, Gracia-Lor E, Sancho JV, Hernández F. 2012. Importance of MS selectivity and chromatographic separation in LC-MS/MS-based methods when investigating pharmaceutical metabolites in water. Dipyrone as a case of study. J Mass Spectrom. 47:1040–1046.
  • Jedziniak P, Szprengier- Juszkiewicz T, Pietruk K, Śledzińska E, Żmudzki J. 2012. Determination of non-steroidal anti-inflammatory drugs and their metabolites in milk by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 403:2955–2963.
  • Malone EM, Dowling G, Elliott CT, Kennedy DG, Regan L. 2009. Development of a rapid, multi-class method for the confirmatory analysis of anti-inflammatory drugs in bovine milk using liquid chromatography tandem mass spectrometry. J Chromatogr A. 1216:8132–8140.
  • Ojha A, Rathod R, Padh H. 2009. Quantification of 4-methylaminoantipyrine, the active metabolite of dipyrone, in human plasma. Bioanalysis. 1:293–298.
  • Penney L, Bergeron C, Wijewickreme A. 2005. Simultaneous determination of residues of dipyrone and its major metabolites in milk, bovine muscle, and porcine muscle by liquid chromatography/mass spectrometry. J AOAC Int. 88:496–504.
  • Shen J, Pang G, Xie L, Chen P, Han R. 2007. [Analysis of three metabolite residues of dipyrone in bovine muscle and pork muscle using high performance liquid chromatography]. Se pu. 25:844–847.
  • Sistovaris N, Pola W, Wolhoff H. 1983. Thin-layer chromatographic determination of major metamizole metabolites in serum and urine. J Chromatogr. 274:289–298.
  • Suarez-Kurtz G, Ribeiro FM, Estrela RCE, Vicente FL, Struchiner CJ. 2001. Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone. Braz J Med Biol Res. 34:1475–1485.
  • Taylor PJ. 2005. Matrix effects: the Achilles heel of quantitative high performance liquid chromatography–electrospray–tandem mass spectrometry. Clin Biochem. 38:328–334.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.