599
Views
28
CrossRef citations to date
0
Altmetric
Original Articles

Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS

, , , , , & show all
Pages 970-976 | Received 16 Sep 2012, Accepted 16 Mar 2013, Published online: 24 May 2013

References

  • AOAC. 2004. Measurement Uncertainty in the Testing Laboratory. AOAC International Training Course, Gaithersburg, Maryland, USA.
  • Boison JO, Asea PA, Matus JL. 2012. Validation of a new screening, determinative, and confirmatory multi-residue method for nitroimidazoles and their hydroxy metabolites in turkey muscle tissue by liquid chromatography-tandem mass spectrometry. Drug Test Anal. Suppl 1:130–138.
  • Cannavan A, Kennedy DG. 1997. Determination of dimetridazole in poultry tissues and eggs using liquid chromatography-thermospray mass spectrometry. Analyst. 122:963–966.
  • Daeseleire E, De Ruyck H, Van Renterghem R. 2000. Rapid confirmatory assay for the simultaneous detection of ronidazole, metronidazole and dimetridazole in eggs using liquid chromatography–tandem mass spectrometry. Analyst. 125:1533–1535.
  • Dobias L, Cerna M, Rossner P, Sram R. 1994. Genotoxicity and carcinogenicity of metronidazole. Mutat Res. 317:177–194.
  • European Commission. 1993. Commission Regulation (EC) No. 3426/93, 14 December 1993. Off J Eur Commun. L312: 15.
  • European Commission. 1995. Commission Regulation (EC) No. 1798/95, 25 July, 1995. Off J Eur Comm. L174: 20.
  • European Commission. 1996. Council Directive 96/23/EC of 29 April 1996 on measures to monitor certain substances and residues thereof in live animals and animal products and repealing Directives 85/358/EEC and 86/469/EEC and 89/187/EEC and 91/664/EEC. Off J Eur Commun. L125: 10–32.
  • European Commission. 1998. Commission Regulation (EC) No. 613/98. Off J Eur Commun. L82: 14.
  • European Commision. 2002. Commission Decision 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Union. L221: 8–36.
  • Granja RHMM, Niño AMM, Rabone F, Niño REM, Cannavan A, Salerno AG. 2008. Validation of radioimmunoassay screening methods for β-agonists in bovine liver according to Commission Decision 2002/657/EC. Food Addit Contam Part A. 25:1475–1481.
  • Granja RHMM, Niño AMM, Zucchetti R, Niño REM, Patel R, Salerno AG. 2009. Determination of erythromycin and tylosin residues in honey by LC/MS/MS. J AOAC Int. 92:975–980.
  • International Organization for Standardization (ISO). 2000. ISO 11843–2: 2000 Capability of detection – Part 2: Methodology in the linear calibration case. Geneva, Switzerland: International Organization for Standardization (ISO).
  • International Organization for Standardization (ISO). 2005. ISO/IEC 17025: 2005 General requirements for the competence of testing and calibration laboratories. Geneva, Switzerland: International Organization for Standardization.
  • Polzer J, Gowik P. 2001. Validation of a method for the detection and confirmation of nitroimidazoles and corresponding hydroxy metabolites in turkey and swine muscle by means of gas chromatography-negative ion chemical ionization mass spectrometry. J Chromatogr B. 761:47–60.
  • Sams MJ, Strutt PR, Barnes KA, Damant AP, Rose MD. 1998. Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry. Analyst. 123:2545–2549.
  • SDA-Ministry of Agriculture and Supply. 2009. Brazilian Normative IN-24/2009 of July 14th 2009. Brazil: SDA-Ministry of Agriculture and Supply.
  • Tölgyesi A, Sharma VK, Fekete S, Fekete J, Simon A, Farkas S. 2012. Development of a rapid method for the determination and confirmation of nitroimidazoles in six matrices by fast liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 64–65:40–48.
  • Voogd CE, van der Stel JJ, Jacobs JJ. 1979. The mutagenic action of nitroimidazoles. IV. A comparison of the mutagenic action of several nitroimidazoles and some imidazoles. Mutation research. 66:207–221.
  • Wang JH. 2001. Determination of three nitroimidazole residues in poultry meat by gas chromatography with nitrogen-phosphorus detection. J Chromatogr A. 918:435–438.
  • Xia X, Wang Y, Wang X, Li Y, Zhong F, Li X, Huang Y, Ding S, Shen J. 2012. Validation of a method for simultaneous determination of nitroimidazoles, benzimidazoles and chloramphenicols in swine tissues by ultra-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 12:1379–1389.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.