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Original Articles

Investigation of the persistence of rafoxanide residues in bovine milk and fate during processing

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Pages 1087-1095 | Received 20 Sep 2012, Accepted 16 Mar 2013, Published online: 28 May 2013

References

  • Anastasio A, Veneziano V, Capurro E, Rinaldi L, Cortesi ML, Rubino R, Danaher M, Cringoli G. Fate of eprinomectin in goat milk abd cheeses with different ripening times following pour-on administration. J Food Protect. 98: 1097–1101.
  • Animal Health Ireland. 2011. ‘Liver fluke the facts’ Animal Health Ireland, Parasites Leaflet Number 5, Version 1 July 2011. Carrick-on-Shannon, County Leitrim: Animal Health Ireland; Available from: www.animalhealthireland.ie
  • European Commission. 2009. Commission implementing regulation (EC) No 470/2009 of the European Parliament and of the Council of 6 May 2009 laying down Community procedures for the establishment of residue limits of pharmacologically active substances in foodstuffs of animal origin, repealing Council Regulation (EEC) No 2377/90 and amending Directive 2001/82/EC of the European Parliament and of the Council and Regulation (EC) No 726/2004 of the European Parliament and of the Council. Off J Eur Commun. L152:11–22.
  • European Union. 2009. Commission implementing regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Off J Eur Commun. L15:1–70.
  • European Union. 2012a. Commission implementing regulation (EU) No 201/2012 of 8 March 2012 Amending the Annex to Regulation (EU) No 37/2010 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin, as regards the substance nitroxynil. Off J Eur Commun. L71:37–39.
  • European Union. 2012b. Commission implementing regulation (EU) No 221/2012 of 14 March 2012 amending the Annex to Regulation (EU) No 37/2010 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin, as regards the substance closantel. Off J Eur Commun. L75:7–9.
  • European Union. 2012c. Commission implementing regulation (EU) No 222/2012 of 14 March 2012 amending the Annex to Regulation (EU) No 37/2010 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin, as regards the substance triclabendazole. Off J Eur Commun. L75:10–11.
  • European Union. 2012d. Commission implementing regulation (EU) No 466/2012 of 1 June 2012 amending the Annex to Regulation (EU) No 37/2010 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin, as regards the substance clorsulon. Off J Eur Commun. L143:2–4.
  • Cooper KM, Whelan M, Danaher M, Kennedy DG. Stability during cooking of anthelmintic veterinary drug residues in beef. Food Addit Contam. 28:155–165.
  • Dedek W, Grahl R, Schwarz H, Liebaug E. 1978. Metabolism, residue and excretion of the anthelmintic 131I-rafoxanid in blood, milk, meat and urine of lactating cows. Arch Exp Veterinarmed. 32:951–955.
  • Dedek W, Schwarz H, Liebaug E. 1976. Degradation and elimination of the anthelminitic 131I-rafoxanid in cattle and sheep. Arch Exp Veterinarmed. 30:423–426.
  • Ghoneim MM, El-Ries M, Hassanein AM, Abd-Elaziz AM. Voltammetric assay of the anthelmintic veterinary drug nitroxynil in bulk form and formulation at a mercury electrode. J Pharm Biomed Anal. 41:1268–1273.
  • Imperiale F, Ortiz P, Cabrera M, Farias C, Sallovitz JM, Iezzi S, Perez J, Alvarez L, Lanusse C. Residual concentrations of the Flukicidal compound triclabendazole in dairy cows’ milk and cheese. Food Addit Contam. 28:438–445.
  • Knubben-Schweizer G, Rüegg S, Torgerson PR, Rapsch C, Grimm F, Hässig M, Deplazes P, Braun U. Control of bovine fasciolosis in dairy cattle in Switzerland with emphasis on pasture management. Vet J. 186:188–191.
  • Mezo M, Gonzalez-Warleta M, Castro-Hermida JA, Ubeira FM. Evaluation of the flukicide treatment policy for dairy cattle in Galicia (NW Spain). Vet Parasitol. 157:235–243.
  • Michels M, Meuldermanns W, Heykants J. 1987. The metabolism and fate of closantel (Flukiver) in sheep and cattle. Drug Metab Rev. 18:235–251.
  • Moreno L, Imperiale F, Mottier L, Alvarez L, Lanusse C. Comparison of milk residue profiles after oral and subcutaneous administration of benzimidazole anthelmintics to dairy cows. Anal Chim Acta. 536:91–99.
  • National Food Residue Database – Residue Testing Plan for Ireland (Targeted Samples), 2008 [Internet]. [cited 2012 Sep 10]. Available from: http://nfrd.teagasc.ie/study_main.asp?Year=2008%7C2009&SType=5&FCat=&FSCat=&NoFiltF=&NoFiltNC=&NoPreFilter=1&Food=&ResCat=&ResSCat=&Res=&filt=1&StudyID=268&caller=2
  • O’Brien B, Jordan K, Danaher M. Update on the use of Flukicides. Irish Vet J. 63:11–13.
  • Power C, Sayers R, O’Brien B, Bloemhoff Y, Danaher M, Furey A, Jordan K. Partitioning of nitroxynil, oxyclozanide and levamisole residues from milk to cream, skim milk and skim milk powder. Int J Dairy Technol. 65:503–506.
  • Rahman MM, Samad MA. Prevalence of subclinical gastrointestinal parasitosis and their effects on milk production with therapeutic management in red Chittagong cattle. Bangl J Vet Med. 8:11–16.
  • Sangster NC. Managing parasiticide resistance. Vet Parasitol. 98:89–109.
  • The European Agency for the Evaluation of Medical Products Veterinary Medicines and Inspections. 1999. Committee for Veterinary Medicinal Products. Rafoxanide summary report (1) [Internet]. EMEA/MRL/636/99- FINAL. EMA July 1999 London, UK: The European Agency for the Evaluation of Medical Products Veterinary Medicines and Inspections; [cited 2012 Sept 20]. Available from: http://www.emea.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report /2009/11/WC500015821.pdf
  • [VMD] Veterinary Medicines Directorate [Internet]. 2008. Surrey, UK: VMD; [cited 2012 Sept 20]. Available from: http://www.vmd.defra.gov.uk/
  • Whelan M, Bloemhoff Y, Furey A, Sayers R, Danaher M. Investigation of the persistence of Nitroxynil residues in milk from lactating dairy cows by ultra performance liquid chromatography tandem mass spectrometry. J Agric Food Chem. 59:7793–7797.
  • Whelan M, Chirollo C, Furey A, Cortesi ML, Anastasio A, Danaher M. Investigation of the persistence of levamisole and oxyclozanide in milk and fate in cheese. J Agric Food Chem. 58:12204–12209.
  • Whelan M, Kinsella B, Furey A, Moloney M, Cantwell H, Lehotay S, Danaher M. Determination of anthelmintic drug residues in milk using ultra ‘high’ performance liquid chromatography-tandem mass spectrometry with rapid polarity switching. J Chromratogr. 1217:4612–4622.
  • Yeung HS, Ching WH, Lai SSL, Lee WO, Wong YT. Quantitative analysis of Closantel and Rafoxanide in Bovine and Ovine muscles by high-performance liquid chromatography with fluorescence detection. J AOAC Int. 93:1672–1677.
  • Yeung HS, Lee WO, Wong YT. Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS. J Sep Sci. 33:206–211.

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