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Original Articles

Fumonisins in plant-origin food and fodder – a review

, , , , &
Pages 1626-1640 | Received 23 Oct 2012, Accepted 16 May 2013, Published online: 09 Jul 2013

References

  • Abbas HK, Cartwright RD, Shier WT, Abouzied MM, Bird CB, Rice LG, Ross PF, Sciumbato GL, Meredith FI. 1998. Natural occurrence of fumonisins in rice with Fusarium sheath rot disease. Plant Dis. 82:22–25.
  • Abbas HK, Riley RT. 1996. The presence and phytotoxicity of fumonisins and aal-toxin in alternaria alternata. Toxicon. 34:133–136.
  • Afolabi CG, Ojiambo PS, Ekpo EJA, Menkir A, Bandyopadhyay R. 2007. Evaluation of maize inbred lines for resistance to Fusarium ear rot and fumonisin accumulation in grain in tropical Africa. Plant Dis. 91:279–286.
  • Almeida AP, Corrêa B, Mallozzi MAB, Sawazaki E, Valente Soares LM. 2000. Mycoflora and aflatoxin/fumonisin production by fungal isolates from freshly harvested corn hybrids. Braz J Microbiol. 31:321–326.
  • Anfossi L, Calderara M, Baggiani C, Giovannoli C, Arletti E, Giraudi G. 2010. Development and application of a quantitative lateral flow immunoassay for fumonisins in maize. Anal Chim Acta. 682:104–109.
  • Atukwase A, Kaaya AN, Muyanja C. 2012. Dynamics of Fusarium and fumonisins in maize during storage – a case of the traditional storage structures commonly used in Uganda. Food Contr. 26:200–205.
  • Azaiez I, Meca G, Manyes L, Fernández-Franzón M. 2013. Antifungal activity of gaseous allyl, benzyl and phenyl isothiocyanate in vitro and their use for fumonisins reduction in bread. Food Contr. 32:428–434.
  • Azaiez I, Meca G, Manyes L, Luciano FB, Fernández-Franzón M. 2013. Study of the chemical reduction of the fumonisins toxicity using allyl, benzyl and phenyl isothiocyanate in model solution and in food products. Toxicon. 63:37–146.
  • Bartók T, Szécsi Á, Szekeres A, Mesterházy Á, Bartók M. 2006. Detection of new fumonisin mycotoxins and fumonisin-like compounds by reversed-phase high-performance liquid chromatography/electrospray ionization ion trap mass spectrometry. Rapid Comm Mass Spectrom. 20:2447–2462.
  • Bartók T, Tölgyesi L, Mesterházy Á, Bartók M, Szécsi Á. 2010. Identification of the first fumonisin mycotoxins with three acyl groups by ESI-ITMS and ESI-TOFMS following RP HPLC separation: palmitoyl, linoleoyl and oleoyl EFB1 fumonisin isomers from a solid culture of Fusarium verticillioides. Food Addit Contam A. 27:1714–1723.
  • Bennett GA, Richard JL, Eckhoff SR. 1996. Distribution of fumonisins in food and feed products prepared from contaminated corn. Adv Exp Med Biol. 392:317–322.
  • Berthiller F, Crews C, Dall’Asta Ch, De Saeger S, Haesaert G, Karlovsky P, Oswald IP, Seefelder W, Speijers G, Stroka J. 2013. Masked mycotoxins: a review. Mol Nutr Food Res. 57:165–186.
  • Bii F, Wanyoike W, Nyende AB, Gituru RW, Bii C. 2012. Fumonisin contamination of maize (Zea mays) in aflatoxin “hot” zones in Eastern province of Kenya. Afr Health Sci. 20:28–36.
  • Bittencourt ABF, Oliveira CAF, Dilkin P, Correa B. 2005. Mycotoxin occurrence in corn meal and flour traded in Sao Paulo, Brazil. Food Contr. 16:117–120.
  • Bojja RS, Cerny RL, Proctor RH, Du L. 2004. Determining the biosynthetic sequence in the early steps of the fumonisin pathway by use of three gene-disruption mutants of Fusarium verticillioides. J Agric Food Chem. 52:2855–2860.
  • Bolger M, Coker RD, DiNovi M, Gaylor D, Gelderblom W, Olsen M, Paster N, Riley RT, Shephard G, Speijers GJA. 2001. Fumonisins. JECFA Join FAO/WHO expert committee on food additives. Safety evaluation of certain mycotoxins in food [Internet]. Geneva: WHO; [cited 2012 Sep 14]. Available from: http://www.inchem.org/documents/jecfa/jecmono/v47je03.htm
  • Bryła M, Jędrzejczak R, Roszko M, Szymczyk K, Obiedziński MWO, Sękul J, Rzepkowska M. 2013. Application of molecularly imprinted polymers to determine B1, B2, and B3 fumonisins in cereal products. J Sep Sci. 36:578–584.
  • Bullerman LB, Bianchini A. 2007. Stability of mycotoxins during food processing. Int J Food Microbiol. 119:140–146.
  • Bullerman LB, Bianchini HMA, Jackson LS, Jablonski J, Ryu D. 2008. Reduction of fumonisin B1 in corn grits by single-screw extrusion. J Agric Food Chem. 56:2400–2405.
  • Castells M, Marín S, Sanchis V, Ramos AJ. 2008. Distribution of fumonisins and aflatoxins in corn fractions during industrial cornflake processing. Int J Food Microbiol. 123:81–87.
  • Castelo MM, Jackson LS, Hanna MA, Reynolds BH, Bullerman LB. 2001. Loss of fumonisin B1 in extruded and baked corn-based foods with sugars. J Food Sci. 66:416–421.
  • Castelo MM, Sumner SS, Bullerman LB. 1998. Stability of fumonisins in thermally processed corn products. J Food Prot. 61:1030–1033.
  • Choi YE, Xu JR. 2010. The cAMP signaling pathway in Fusarium verticillioides is important for conidiation, plant infection, and stress responses but not fumonisin production. Mol Plant Microbe Interact. 23:522–533.
  • Clements MJ, Kleinschmidt CE, Maragos CM, Pataky JK, White DG. 2003. Evaluation of inoculation techniques for fusarium ear rot and fumonisin contamination of corn. Plant Dis. 87:147–153.
  • Collins TFX, Sprando RL, Black TN, Olejnik N, Eppley RM, Shackelford ME, Howard PC, Rorie JI, Bryant M, Ruggles DI. 2006. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 44:161–169.
  • European Commission. 2006. Opinion of the Scientific Committee on Food on Fusarium toxins. Expressed on 22 June 2000. Available from: http://ec.europa.eu/food/fs/sc/scf/out65_en.pdf
  • European Commission. 2006. Commission Recommendation (2006/576/EC) of 17 August 2006 on the presence of deoxynivalenol, zearalenone, ochratoxin A, T-2 and HT and fumonisins in products intended for animal feeding. Off J Eur Union. L299:7–9.
  • European Commission. 2006. Commission Regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Off J Eur Union. L364:5-24.
  • European Commission. 2006. Commission Regulation (WE) (EC) No 1126/2007 of 28 September 2007 amending Regulation (EC) No 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products.
  • Czerwiecki L. 1998. Determination of selected mycotoxins in food part II: selection of optimised conditions for the determination of fumonisin B1 and B2 in corn products by means of high-performance liquid chromatography. Roczniki PZH. 49:13–24.
  • Dall’Asta C, Falavigna C, Galaverna G, Battilani P. 2012. Role of maize hybrids and their chemical composition in fusarium infection and fumonisin production. J Agric Food Chem. 60:3800–3808.
  • Dall’Asta C, Falavigna C, Galavern G, Dossen A, Marchelli R. 2010. In vitro digestion assay for determination of hidden fumonisins in maize. J Agric Food Chem. 58:12042–12047.
  • Dall’Asta C, Galaverna G, Mangia M, Sforza S, Dossena A, Marchelli R. 2009. Free and bound fumonisins in gluten-free food products. Mol Nutr Food Res. 53:492–499.
  • Dall’Asta C, Mangia M, Berthiller F, Molinelli A, Sulyok M, Schuhmacher R, Krska R, Galaverna G, Dossena A, Marchelli R. 2009. Difficulties in fumonisin determination: the issue of hidden fumonisins. Anal Bioanal Chem. 395:1335–1345.
  • Dall’Asta C, Pia Scarlato A, Pia Scarlato G, Brighenti F, Pellegrini N. 2012. Dietary exposure to fumonisins and evaluation of nutrient intake in a group of adult celiac patient on a gluten-free diet. Mol Nutr Food Res. 56:632–640.
  • Danielsen S, Jensen DF. 1998. Relationships between seed germination, fumonisin content, and Fusarium verticillioides infection in selected maize samples from different regions of Costa Rica. Plant Pathol. 47:609–614.
  • Desai K, Sullards MC, Allegood J, Wang E, Schmelz EM, Hartl M, Humpf HU, Liotta DC, Peng Q, Merrill Jr AH. 2002. Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis. Biochim Biophys Acta. 1585:188–192.
  • Desjardins AE, Proctor RH. 2007. Molecular biology of Fusarium mycotoxins. Int J Food Microbiol. 119:47–50.
  • Di Mavungu D, De Saeger S. 2011. Masked mycotoxins in food and feed: challenges and analytical approaches. Determining mycotoxins and mycotoxigenic fungi in food and feed, Vol. 2. Cambridge (UK): Woodhead Publishing; p. 385–400.
  • Dilkin P, Mallmann CA, Almeida CAA, Stefanon EB, Fontana FZ, Milbradt EL. 2002. Production of fumonisins by strains of Fusarium Moniliforme according to temperature, moisture and growth period. Braz J Microbiol. 33:CIT0027–118.
  • Falavigna C, Cirlini M, Galaverna G, Sforza S, Dossena A, Dall’Asta Ch. 2012. LC/ESI-MS/MS analysis outlines the different fumonisin patterns produced by F. verticillioides in culture media and in maize kernels. J Mass Spectrom. 47:1170–1176.
  • Fandohan P, Gnonlonfin B, Hell K, Marasas WFO, Wingfield MJ. 2005. Natural occurrence of Fusarium and subsequent fumonisin contamination in preharvest and stored maize in Benin, West Africa. Int J Food Microbiol. 99:173–183.
  • Fandohan P, Hell K, Marasas WFO, Wingfield MJ. 2003. Infection of maize by Fusarium species and contamination with fumonisin in Africa. Afr J Biotechnol. 2:570–579.
  • FAO/WHO. 2011. FAO/WHO-World Health Organization. Evaluation of Certain Food Additives & Contaminants. 2011. Seventy-forth report of the Joint FAO/WHO Expert Committee on Food Additives, WHO Technical Report Series 966. Available from: http://whqlibdoc.who.int/trs/WHO_TRS_966_eng.pdf
  • FAO/WHO. 2012. FAO/WHO-Joint FAO/WHO Food Standards Programme Codex Committee on Contaminants in Foods. 2012. Sixth Session, Discussion Paper on Proposed Draft Maximum Levels for Fumonisins in Maize and Maize-Products and Associated Sampling Plans, Codex Alimentarius Commission. Available from: http://ec.europa.eu/food/fs/ifsi/eupositions/cccf/docs/cccf_6th_agenda_item_12a.pdf
  • Federico FJ, Funes GJ, Salas MP, Resnik SL. 2010. Natural occurrence of fumonisins in corn puff in Argentina. Mycotox Res. 26:273–278.
  • Font G, Azaiez I, Meca G, Fernández-Franzón M. 2012. Detoxification of fumonisins by isothiocyanates. Toxicol Lett. 211:S98–S99.
  • Gaspardo B, Del Zotto S, Torelli E, Cividino SR, Firrao G, Della Riccia G, Stefanon B. 2012. A rapid method for detection of fumonisins B1 and B2 in corn meal using Fourier transform near infrared (FT-NIR) spectroscopy implemented with integrating sphere. Food Chem. 135:1608–1612.
  • Gazzotti T, Zironi E, Lugoboni B, Barbarossa A, Piva A, Pagliuca G. 2011. Analysis of fumonisins B1, B2 and their hydrolysed metabolites in pig liver by LC–MS/MS. Food Chem. 125:1379–1384.
  • Gelderblom WC, Jaskiewicz K, Marasas WF, Thiel PG, Horak RM, Vleggaar R, Kriek NP. 1988. Fumonisins – novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme. Appl Environ Microbiol. 54:1806–1811.
  • Gelderblom WCA, Cawood ME, Snyman SD, Vleggaar R, Marasas WFO. 1993. Structure-activity-relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays. Food Chem Toxicol. 31:407–414.
  • Grenier B, Bracarense AP, Schwartz HE, Trumel C, Cossalter AM, Schatzmayr G, Kolf-Clauw M, Moll WD, Oswald IP. 2012. The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids. Biochem Pharmacol. 15:1465–1473.
  • Hadj Ali W, Derrien D, Alix F, Pérollier C, Lépine O, Bayoudh S, Chapuis-Hugon F, Pichon V. 2010. Solid-phase extraction using molecularly imprinted polymers for selective extraction of a mycotoxin in cereals. J Chromatogr A. 1217:CIT00328–6673.
  • Harrer H, Laviad EL, Humpf HU, Futerman AH. 2013. Identification of N-acyl-fumonisin B1 as new cytotoxic metabolites of fumonisin mycotoxins. Mol Nutr Food Res. 57:516–522.
  • Heinl S, Hartinger D, Thamhesl M, Vekiru E, Krska R, Schatzmayr G, Moll W-D, Grabherr R. 2010. Degradation of fumonisin B1 by the consecutive action of two bacterial enzymes. J Biotech. 145:120–129.
  • Hennigen MR, Sanchez S, Di Benedetto NM, Longhi A, Torroba JE, Valente Soares LM. 2000. Fumonisin levels in commercial corn products in Buenos Aires. Argentina Food Addit Contam. 17:55–58.
  • Howard PC, Couch LH, Patton RE, Eppley RM, Doerge DR, Churchwell MI, Marques MM, Okerberg C. 2002. Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. Toxicol Appl Pharmacol. 185:153–165.
  • Hui-Zhi G, Rong J, Yan-Xi L, Hong-Yu Z, Bing L, Yue Z, Lin S, Fei Y, Jun Y. 2009. Occurrence of fumonisin B1 in corn from the main corn-producing areas of China. Mycopathologia. 167:31–36.
  • Humpf HU, Voss KA. 2004. Effects of thermal food processing on the chemical structure and toxicity of fumonisin mycotoxins. Mol Nutr Food Res. 48:255–269.
  • Jackson LS, Jablonski J, Bullerman LB, Bianchini A, Hanna MA, Voss KA, Hollub AD, Ryu D. 2011. Reduction of fumonisin B1 in corn grits by twin-screw extrusion. J Food Sci. 76:T150–T155.
  • Jackson LS, Katta SK, Fingerhut DD, DeVries JW, Bullerman LB. 1997. Effects of baking and frying on the fumonisin B1 content of corn-based foods. J Agric Food Chem. 45:4800–4805.
  • Katta SK, Cagampang AE, Jackson LS, Bullerman LB. 1997. Distribution of Fusarium molds and fumonisins in drymilled corn fractions. Cereal Chem. 74:858–863.
  • Katta SK, Jackson LS, Sumner SS, Hanna MA, Bullerman LB. 1CIT0035. Effect of temperature and screw speed on stability of fumonisin B1 in extrusion-cooked corn grits. Cereal Chem. 76:16–20.
  • Khayoon WS, Saad B, Salleh B, Ismail NA, Manaf NHA, Latiff AA. 2010. A reversed phase high performance liquid chromatography method for the determination of fumonisins B1 and B2 in food and feed using monolithic column and positive confirmation by liquid chromatography/tandem mass spectrometry. Anal Chim Acta. 679:91–97.
  • Kim EK, Scott PM, Lau BPY. 2003. Hidden fumonisin in corn flakes. Food Addit Contam. 20:161–169.
  • Krska R. 2009. Mycotoxins. Anal Bioanal Chem. 395:1203–1204.
  • Krska R, Welziga E, Boudra H. 2007. Analysis of Fusarium toxins in feed. Animal Feed Sci Tech. 137:241–264.
  • Kuiper-Goodman T. 2011. Risk assessment and risk management of mycotoxins in food. Determining mycotoxins and mycotoxigenic fungi in food and feed, Vol. 2. Cambridge (UK): Woodhead Publishing; p. 131.
  • Lazzaro I, Susca A, Mulè G, Ritieni A, Ferracane R, Marocco A, Battilani P. 2012. Effects of temperature and water activity on FUM2 and FUM21 gene expression and fumonisin B production in Fusarium verticillioides. Eur J Plant Pathol. 134:685–695.
  • Leslie JF, Bandyopadhyay R, Visconti A. 2008. Mycotoxins, detection methods, management. Public health and agricultural trade. Wallingford (CT): CABI Publishing.
  • Li C, Liang Y, Ting Yang W, Huang-Fum WG. 2012. Rapid determination of fumonisins B1 and B2 in corn by liquid chromatography–tandem mass spectrometry with ultrasonic extraction. J Chromatogr Sci. 50:57–63.
  • Logrieco A, Ferracane R, Visconti A, Ritieni A. 2010. Natural occurrence of fumonisin B2 in red wine from Italy. Food Addit Contam. 27:1136–1141.
  • Logrieco A, Mulé G, Moretti A, Bottalico A. 2002. Toxigenic Fusarium species and mycotoxins associated with maize ear rot in Europe. Eur J Plant Pathol. 108:597–609.
  • Lucci P, Derrien D, Alix F, Pérollier C, Bayoudh S. 2010. Molecularly imprinted polymer solid-phase extraction for detection of zearalenone in cereal sample extracts detection. Anal Chim Acta. 672:15–19.
  • Mallmannt CA, Santuriot IM, Dilkin P. 2001. Fumonisin B1 levels in cereals and feeds from southern Brazil. Arq Inst Biol São Paulo. 68:41–45.
  • Mansfield MA, Archibald DD, Jones AD, Kuldau GA. 2007. Relationship of sphinganine analog mycotoxin contamination in maize silage to seasonal weather conditions and to agronomic and ensiling practices. Phytopathology. 97:504–511.
  • Mazzoni E, Scandolara A, Giorni P, Pietri A, Battilani P. 2011. Field control of Fusarium ear rot, Ostrinia nubilalis (Hübner), and fumonisins in maize kernels. Pest Man Sci. 67:458–465.
  • Merrill Jr AH, Sullards MC, Wang E, Voss KA, Riley RT. 2001. Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environ Health Perspect. 109:283–289.
  • Molinelli A, Grossalber K, Krska R. 2009. A rapid lateral flow test for the determination of total type B fumonisins in maize. Anal Bioanal Chem. 395:1309–1316.
  • Montis V, Pasquali M, Visentin I, Karlovsky P, Cardinale F. 2013. Identification of a cis-acting factor modulating the transcription of FUM1, a key fumonisin-biosynthetic gene in the fungal maize pathogen Fusarium verticillioides. Fungal Genet Biol. 51:42–49.
  • Munkvold GP, Desjardins AE. 1997. Fumonisins in maize. Can we reduce their occurrence?. Plant Dis. 81:556–564.
  • Munkvold GP, Hellmich RL, Rice LG. 1CIT0035. Comparison of fumonisin concentrations in kernels of transgenic bt maize hybrids and nontransgenic hybrids. Plant Dis. 83:130–138.
  • Myung K, Li S, Butchko RAE, Busman M, Proctor RH, Abbas HK, Calvo AM. 2009. FvVE1 regulates biosynthesis of fumonisins and fusarins in Fusarium verticillioides. J Agric Food Chem. 57:5089–5094.
  • Norred WP, Bacon ChW, Riley RT, Voss KA, Meredith FI. 1CIT0035. Screening of fungal species for fumonisin production and fumonisin – like disruption of sphingolipid biosynthesis. Mycopathologia. 146:91–98.
  • Nuryono, Noviandi CT, Böhm J, Agus A, Wedhastri S, Maryudani YB, Razzazi-Fazeli E. 2004. Occurrence of fumonisins (B1, B2, B3) in maize-based food and feed samples from Indonesia. Mycotox Res. 20:2–9.
  • Pagliuca G, Zironi E, Ceccolini A, Matera R, Serrazanetti GP, Pivac A. 2005. Simple method for the simultaneous isolation and determination of fumonisin B1and its metabolite aminopentol-1 in swine liver by liquid chromatography–fluorescence detection. J Chromatogr B. 819:97–103.
  • Park JW, Scott PM, Lau BPY. 2013. Analysis of N-fatty acyl fumonisins in alkali-processed corn foods. Food Sci Biotechnol. 22;Suppl:147–152.
  • Park JW, Scott PM, Lau BPY, Lewis DA. 2004. Analysis of heat-processed corn foods for fumonisins and bound fumonisins. Food Addit Contam. 21:1168–1178.
  • Parsons MW, Munkvold GP. 2012. Effects of planting date and environmental factors on fusarium ear rot symptoms and fumonisin B1 accumulation in maize grown in six North American locations. Plant Pathol. 61:1130–1142.
  • Pascale M, Visconti A, Prończuk M, Wiśniewska H, Chełkowski J. 1997. Accumulation of fumonisins in maize hybrids inoculated under field conditions with Fusarium moniliforme sheldon. J Sci Food Agric. 74:1–6.
  • Picot A, Ch B, Pinson-Gadais L, Piraux F, Caron D, Ch L, Richard-Forget F. 2011. The dent stage of maize kernels is the most conducive for fumonisin biosynthesis under field conditions. Appl Environ Microbiol. 77:8382–8390.
  • Pineiro M, Miller J, Silva G, Musser S. 1CIT0035. Effect of commercial processing on fumonisin concentrations of maizebased foods. Mycotox Res. 15:2–12.
  • Pleadin J, Persi N, Mitak M, Zadravec M, Sokolovic M, Vulic A, Jaki V, Brstilo M. 2012. The natural occurrence of t-2 toxin and fumonisins in maize samples in croati. Bull Environ Contam Toxicol. 88:863–866.
  • Rai M, Varma A, editors. 2010. Fusarium and fumonisins in maize in South America. Mycotoxins in food, feed an095ioweapons. Berlin: Edition Springer-Verlag GmbH, Part 2; p. 179–200.
  • Ren Y, Zhang Y, Han S, Han Z, Wu Y. 2011. Simultaneous determination of fumonisins B1, B2 and B3 contaminants in maize by ultra high-performance liquid chromatography tandem mass spectrometry. Anal Chim Acta. 692:138–145.
  • Rheeder JP, Marasas WFO, Vismer HF. 2002. Production of fumonisin analogs by Fusarium species. Appl Environ Microbiol. 68:2101–2105.
  • Ross PF, Nelson PE, Richard JL, Osweiler GD, Rice LG, Plattner RD, Wilson TM. 1990. Production of fumonisins by fusarium moniliforme and fusarium proliferatum isolates associated with equine leukoencephalomalacia and a pulmonary edema syndrome in swine. Appl Environ Microbiol. 56:3225–3326.
  • Ross PF, Rice LG, Osweiler GD, Nelson PE, Richard JL, Wilson TM. 1992. A review and update of animal toxicoses associated with fumonisin – contaminated feeds and production of fumonisins by Fusarium isolates. Mycopathologia. 117:109–114.
  • Royer D, Humpf HU, Guy PA. 2004. Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Food Addit Contam. 21:678–692.
  • Saunders DS, Meredith FI, Voss KA. 2001. Control of fumonisin: effects of processing. Environ Health Perspect. 109:CIT0029–336.
  • SCOOP. 2003. Scoop Task 3.2.10: Collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by population of EU member states. [Internet]; [cited 2012 Sep 25]. Available from: http://ec.europa.eu/food/fs/scoop/task/3210.pdf
  • Scott PM. 2012. Recent research on fumonisins: a review. Food Addit Contam. 29:242–248.
  • Scott PM, Lawrance GA. 1992. Liquid chromatographic determination of fumonisins with 4-fluoro-7-nitrobenzofurazan. J Assoc Off Anal Chem. 75:829–834.
  • Seefelder W, Hartl M, Humpf HU. 2001. Determination of N-(carboxymethyl) fumonisin B(1) in corn products by liquid chromatography/electrospray ionization--mass spectrometry. J Agric Food Chem. 49:2146–2151.
  • Seefelder W, Knecht A, Humpf HU. 2003. Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry. J Agric Food Chem. 51:5567–5573.
  • Seiferlein M, Humpf UH, Voss KA, Cameron Sullards M, Allegood JC, Wang E, Merrill Jr AH. 2007. Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites. Mol Nutr Food Res. 51:1120–1130.
  • Senyuva HZ, Ozcan S, Cimen D, Gilbert J. 2008. Deterimation of fumonisns B1 and B2 in corn by liquid chromatography/mass spectrometry with immunoaffinity column cleanup: single-laboratory method validation. J Assoc Off Anal Chem. 91:598–606.
  • Seo JA, Lee YW. 1CIT0035. Natural occurrence of the C series of fumonisins in moldy corn. Appl Environ Microbiol. 65:1331–1334.
  • Shepard GS, Thiel PG, Sydenham EW. 1995. Liquid chromatographic determination of the mycotoxin fumonisin B2 in physiological samples. J Chromatogr A. 692:39–43.
  • Silva L, Fernández-Franzón M, Font G, Pena A, Silveira I, Lino C, Mańes M. 2009. Analysis of fumonisins in corn-based food by liquid chromatography with fluorescence and mass spectrometry detectors. Food Chem. 112:1031–1037.
  • Silva LJG, Lino CM, Pena A. 2007. Occurrence of fumonisins B1 and B2 in Portugese maize and maize-based foods intended for human consumption. Food Addit Contam. 24:381–390.
  • Solfrizo M, de Girolamo A, Visconti A. 2001. Determination of fumonisins B1 and B2 in cornflakes by high performance liquid chromatography and immunoaffinity clean-up. Food Addit Contam. 18:227–235.
  • Soriano JM, Dragacci S. 2004. Occurrence of fumonisins in foods. Food Res Int. 37:985–1000.
  • Soriano JM, González L, Catalá AI. 2005. Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1. Prog Lipid Res. 44:345–356.
  • Stack ME, Eppley RM. 1992. Liquid chromatographic determination of fumonisins B1 and B2 in corn and corn products. J Assoc Off Anal Chem. 75:835.
  • Storari M, Dennert FG, Bigler L, Gessler C, Broggini GAL. 2012. Isolation of mycotoxins producing black aspergilli in herbal teas available on the Swiss market. Food Contr. 26:157–161.
  • Tardieu D, Auby A, Bluteau C. 2008. Determination of fumonisin B1 in animal tissues with immunoaffinity purification. J Chromatogr B. 870:140–144.
  • Thiel PG, Marasas WFO, Sydenham EW, Shephard GS, Gelderblom WCA. 1992. The implications of naturally occurring levels of fumonisins in corn for human and animal health. Mycopathologia. 117:3–9.
  • Torelli E, Firrao G, Bianchi G, Saccardo F, Loccia R. 2012. The influence of local factors on the prediction of fumonisin contamination in maize. J Sci Food Agric. 92:1808–1814.
  • Van der Westhuizen L, Shephard GS, Snyman SD, Abel S, Swanevelder S, Gelderblom WCA. 1998. Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B-1 and other structurally related compounds. Food Chem Toxicol. 36:497–503.
  • Visentin I, Montis V, Döll K, Alabouvette C, Tamietti G, Karlovsky P, Cardinale F. 2012. Transcription of genes in the biosynthetic pathway for fumonisin mycotoxins is epigenetically and differentially regulated in the fungal maize pathogen fusarium verticillioides. Eukaryot Cell. 11:252–259.
  • Voss KA, Bullerman LB, Bianchini A, Hanna MA, Ryu D. 2008. Reduced toxicity of fumonisin B1 in corn grits by single-screw extrusion. J Food Prot. 71:2036–2041.
  • Voss KA, Riley RT, Bacon CW, Meredith FI, Norred WP. 1998. Toxicity and sphinganine levels are correlated in rats fed fumonisin B-1 (FB1) or hydrolyzed FB1. Environ Toxicol Pharmacol. 5:101–104.
  • Voss KA, Riley RT, Jackson LS, Jablonski JE, Bianchini A, Bullerman LB, Hanna MA, Ryu D. 2011. Extrusion cooking with glucose supplementation of fumonisin contaminated corn grits protects against nephrotoxicity and disrupted sphingolipid metabolism in rats. Mol Nutr Food Res. 55:S312–S320.
  • Voss KA, Riley RT, Snook ME, Gelineau-van Waes J. 2009. Reproductive and sphingolipid metabolic effects of fumonisin B1 and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B1 did not cause neural tube defects. Toxicol Sci. 112:459–467.
  • Voss KA, Smith GW, Haschek WM. 2007. Fumonisins: toxicokinetics, mechanism of action and toxicity. Animal Feed Sci Tech. 137:299–325.
  • Wan Norhasima WM, Abdulamir AS, Abu Bakar F, Son R, Norhafniza A. 2009. The health and toxic adverse effects of Fusarium fungal mycotoxin, fumonisins, on human population. Am J Infect Dis. 5:273–281.
  • Wang J, Zhou Y, Wang Q. 2008. Analysis of mycotoxin fumonisins in corn products by high-performance liquid chromatography coupled with evaporative light scattering detection. Food Chem. 107:970–976.
  • Ware GM, Francis O, Knan SS. 1993. Determination of fumonisin B1 in corn by high performance liquid chromatography with fluorescence detection. Anal Lett. 26:1751–1770.
  • Warfield CY, Gilchrist DG. 1CIT0035. Influence of kernel age on fumonisin b1 production in maize by Fusarium moniliforme. Appl Environ Microbiol. 65:2853–2856.
  • Waśkiewicz A, Beszterda M, Goliński P. 2012. Occurrence of fumonisins in food – an interdisciplinary approach to the problem. Food Contr. 26:491–499.
  • Weidenbörner M. 2001. Foods and fumonisins. Eur Food Res Tech. 212:262–273.
  • [WHO-IPCS] World Health Organization e International Programme on Chemical Safety. 2000. Fumonisin B1. Environmental health criteria 219 [Internet]. Geneva: World Health Organization; [cited 2012 Sep 19]. Available from: http://www.inchem.org/documents/ehc/ehc/ehc219.htm
  • Williams LD, Meredith FI, Riley RT. 2004. Fumonisin-ortho-phthalaldehyde derivative is stabilized at low temperature. J Chromatogr B. 806:311–314.
  • Yoshizawa T, Yamashita A, Luo Y. 1994. Fumonisin occurrence in corn from high- and low-risk areas for human esophageal cancer in China. Appl Environ Microbiol. 60:1626–1629.
  • Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sullards MC, et al. 2009. Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. J Biol Chem. 284:4786–4795.

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