Unravelling a vicious circle: animal feed marketed in Costa Rica contains irregular concentrations of tetracyclines and abundant oxytetracycline-resistant Gram-positive bacteria

References

• Association of American Feed Control Officials. 2006. Official Publication. Oxford (IN): Association of American Feed Control Officials.
   Google Scholar
• Barton MD. 2000. Antibiotic use in animal feed and its impact on human health. Nutr Res Rev. 13:279–299.
   PubMed Web of Science ®Google Scholar
• Behme RJ, Shuttleworth R, McNabb A, Colby WD. 1996. Identification of staphylococci with a self-educating system using fatty acid analysis and biochemical tests. J Clin Microbiol. 34:3075–3084.
   PubMed Web of Science ®Google Scholar
• Borràs S, Companyó R, Granados M, Guiteras J, Pérez-Vendrell AM, Brufau J, Medina M, Bosch J. 2011. Analysis of antimicrobial agents in animal feed. TrAC Trends Anal Chem. 30:1042–1064.
   Web of Science ®Google Scholar
• Butaye P, Devriese LA, Haesebrouck F. 2003. Antimicrobial growth promoters used in animal feed: effects of less well-known antibiotics on Gram-Positive bacteria. Clin Microbiol Rev. 16:175–188.
   PubMed Web of Science ®Google Scholar
• Chopra I, Roberts M. 2001. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev. 65:232–260.
   PubMed Web of Science ®Google Scholar
• Collignon P, Powers JH, Chiller TM, Aidara-Kane A, Aarestrup FM. 2009. World Health organization ranking of antimicrobials according to their importance in human medicine: a critical step for developing risk management strategies for the use of antimicrobials in food production animals. Clin Infect Dis. 49:132–141.
   PubMed Web of Science ®Google Scholar
• da Costa PM, Loureiro L, Matos AJF. 2013. Transfer of multidrug-resistant bacteria between intermingled ecological niches: the interface between humans, animals and the environment. Int J Environ Res Public Health. 10:278–294.
   PubMed Web of Science ®Google Scholar
• da Costa PM, Oliveira M, Bica A, Vaz-Pires P, Bernardo F. 2007. Antimicrobial resistance in Enterococcus spp. and Escherichia coli isolated from poultry feed and feed ingredients. Vet Microbiol. 120:122–131.
   PubMed Web of Science ®Google Scholar
• Dang STT, Petersen A, Truong DV, Chu HTT, Dalsgaard A. 2011. Impact of medicated feed on the development of antimicrobial resistance in bacteria at integrated pig-fish farms in Vietnam. Appl Environ Microbiol. 77:4494–4498.
   PubMed Web of Science ®Google Scholar
• DePaola A. 1995. Tetracycline resistance by bacteria in response to oxytetracycline-contaminated catfish feed. J Aquat Anim Health. 7:155–160.
   Google Scholar
• [FDA] U.S. Food and Drug Administration. 2009. Approved Animal Drug Products [Internet]. [cited 2013 Nov 29]. Available from: http://www.accessdata.fda.gov/scripts/AnimalDrugsAtFDA/
   Google Scholar
• [FDA] U.S. Food and Drug Administration. 2010a. New Animal Drugs for Use in Animal Feeds. 21CFR558.
   Google Scholar
• [FDA] U.S. Food and Drug Administration. 2010b. Oral Dosage Form New Animal Drugs. 21CFR520.
   Google Scholar
• Feinman SE. 1998. Antibiotics in animal feed—drug resistance revisited. ASM News. 64:24–30.
   Google Scholar
• Gilchrist MJ, Greko C, Wallinga DB, Beran GW, Riley DG, Thorne PS. 2007. The potential role of concentrated animal feeding operations in infectious disease epidemics and antibiotic resistance. Environ Health Perspect. 115:313–316.
   PubMed Web of Science ®Google Scholar
• Granados-Chinchilla F, Sánchez J, García F, Rodríguez C. 2012. A novel green chemistry method for nonaqueous extraction and high-performance liquid chromatography detection of first-, second-, and third-generation tetracyclines, 4-epitetracycline, and tylosin in animal feeds. J Agric Food Chem. 60:7121–7128.
   PubMed Web of Science ®Google Scholar
• Gutiérrez K, Alfaro M, Granados F, Sánchez J, García F, Rodríguez C. 2010. Microbiological detection of tetracyclines in 9 lots of animal feed produced in Costa Rica: infringement of norms and incongruences with the official labeling. Agron Costarric. 34:145–151.
   Google Scholar
• Kaneda T. 1967. Fatty acids of the genus Bacillus. J Bacteriol. 93:894–903.
   PubMed Web of Science ®Google Scholar
• Kerry J, Hiney M, Coyne R, NicGabhainn S, Gilroy D, Cazabon D, Smith P. 1995. Fish feed as a source of oxytetracycline-resistant bacteria in the sediments under fish farms. Aquacult. 131:101–113.
   Google Scholar
• Kunitsky C, Osterhout J, Sasser M. 2006. Identification of microorganisms using fatty acid methyl ester (FAME) analysis and the MIDI Sherlock® Microbial Identification System. In: Miller MJ, editor. Encyclopedia of rapid microbiological methods. Vol 3. LLC. River Grove (IL): DHI Publishing; p. 1–56.
   Google Scholar
• Lefferts L, Kucharski M, McKenzie S, Walker P. 2006. Feed for food producing animals: a resource on ingredients, the industry, and regulation. Baltimore (MD): The Johns Hopkins Center for a Livable Future, Bloomberg School of Public Health.
   Google Scholar
• Lin C, Bolsen KK, Brent BE, Hart RA, Dickerson JT, Feyerherm AM, Aimutis WR. 1992. Epiphytic microflora on alfalfa and whole-plant corn. J Dairy Sci. 75:2484–2493.
   PubMed Web of Science ®Google Scholar
• Logan NA, Berkeley RC. 1984. Identification of Bacillus strains using the API system. J Gen Microbiol. 130:1871–1882.
   PubMedGoogle Scholar
• Love DC, Davis MF, Bassett A, Gunther A, Nachman KE. 2011. Dose imprecision and resistance: free-choice medicated feeds in industrial food animal production in the United States. Environ Health Perspect. 119:279–283.
   PubMed Web of Science ®Google Scholar
• Lynas L, Currie D, McCaughey WJ, McEvoy JDG, Kennedy DG. 1998. Contamination of animal feedingstuffs with undeclared antimicrobial additives. Food Addit Contam. 15:162–170.
   PubMedGoogle Scholar
• Maciorowski KG, Herrera P, Jones FT, Pillai SD, Ricke SC. 2007. Effects on poultry and livestock of feed contamination with bacteria and fungi. Anim Feed Sci Technol. 133:109–136.
   Web of Science ®Google Scholar
• Marshall BM, Levy SB. 2011. Food Animals and antimicrobials: impacts on human health. Clin Microbiol Rev. 24:718–733.
   PubMed Web of Science ®Google Scholar
• McEwen SA, Fedorka-Cray PJ. 2002. Antimicrobial use and resistance in animals. Clin Infect Dis. 34:SS93–SS106.
   Web of Science ®Google Scholar
• Miranda CD, Zemelman R. 2002. Bacterial resistance to oxytetracycline in Chilean salmon farming. Aquacult. 212:31–47.
   Google Scholar
• Okoli IC, Herbert U, Ozoh P, Udedibie AB. 2005. Antimicrobial resistance profile of Escherichia coli isolates from commercial poultry feeds and feed raw materials. Anim Res Int. 2:322–328.
   Google Scholar
• Over U, Soyletir G. 2000. Catalase-negative Staphylococcus aureus: a rare isolate of human infection. Clin Microbiol Infect. 6:681–682.
   PubMed Web of Science ®Google Scholar
• Prescott JF. 1997. Antibiotics: miracle drugs or pig food? Can Vet J. 38:763–766.
   PubMed Web of Science ®Google Scholar
• Promotora de comercio exterior de Costa Rica. 2013. Estadísticas de comercio exterior [Internet]. [cited 2013 Sep 23]. Available from: http://servicios.procomer.go.cr/estadisticas/inicio.aspx.
   Google Scholar
• Richard-Molard D. 1988. General characteristics of the microflora of grains and seeds and the principal resulting spoilages. In: Multon JL, editor. Preservation and storage of grains, seeds, and their by-products. New York (NY): Lavoisier Publishing, Inc; p. 226–243.
   Google Scholar
• Sapkota AM, Lefferts LY, McKenzie S, Walker P. 2007. What do we feed to food production animals? A review of animal feed ingredients and their potential impacts on human health. Environ Health Perspect. 115:663–670.
   PubMed Web of Science ®Google Scholar
• Stolker AAM, Manti V, Zuidema T, van Egmond H, Deckers ER, Herbes R, Hooglugt J, Heuvel EO, de Jong J. 2013. Carry-over of veterinary drugs from medicated to non medicated feeds in commercial feed manufacturing plants. Food Addit Contam: Part A. 30:1100–1107.
   PubMed Web of Science ®Google Scholar
• Tindall BJ, Rossello-Mora R, Busse HJ, Ludwig W, Kampfer P. 2010. Notes on the characterization of prokaryote strains for taxonomic purposes. Int J Syst Evol Microbiol. 60:249–266.
   PubMed Web of Science ®Google Scholar
• US Government Accountability Office. 2011. Antibiotic Resistance: Data Gaps Will Remain Despite HHS Taking Steps to Improve Monitoring. Washington, DC: GAO-11-406.
   Google Scholar