587
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Development of an ultra-high-performance liquid chromatography coupled to high-resolution quadrupole-Orbitrap mass spectrometry method for the rapid detection and confirmation of illegal adulterated sedative-hypnotics in dietary supplements

, , , &
Pages 1749-1759 | Received 04 Feb 2015, Accepted 13 Apr 2015, Published online: 11 May 2015

References

  • Gao Q, Che B, Zhang Z, Dai H, Guo H. 2008. Identification of 16 sedative-hypnotic drugs in traditional Chinese medicines and health foods by LC-MS/MS. J China Pharm Univ. 39:142–146.
  • Jia W, Chu X, Ling Y, Huang J, Chang J. 2014. High-throughput screening of pesticide and veterinary drug residues in baby food by liquid chromatography coupled to quadrupole Orbitrap mass spectrometry. J Chromatogr A. 1347:122–128.
  • Jin P, Wang Z, Wang W, Zou D, Ma J, Hu X. 2012. Detection of phenobarbital and seven other sedative hypnotics illegally adulterated into Traditional Chinese Medicines and health foods by HPLC-DAD. Chin Pharm J. 47:462–466.
  • Kaufmann A, Butcher P, Maden K, Walker S, Widmer M. 2010. Comprehensive comparison of liquid chromatography selectivity as provided by two types of liquid chromatography detectors (high resolution mass spectrometry and tandem mass spectrometry): ‘Where is the crossover point?’ Anal Chim Acta. 673:60–72.
  • Li X, Shen B, Jiang Z, Huang Y, Zhuo X. 2013. Rapid screening of drugs of abuse in human urine by high-performance liquid chromatography coupled with high resolution and high mass accuracy hybrid linear ion trap-Orbitrap mass spectrometry. J Chromatogr A. 1302:95–104.
  • Liu J, Xiao L, Guan X, Xiong Y, Wang T, Li J. 2011. GC-MS determination of 14 sedative-hypnotic drugs illegal mixed in traditional Chinese medicines and health foods. Chin J Pharm Anal. 31:376–379.
  • Luo J, Tan L, Cao L, Wang Y. 2010. Determination of 15 antiepileptic and hypnotic compounds illegally adulterated into Traditional Chinese Medicines by LC-MS/MS. Chin J Biochem Pharm. 31:162–166.
  • Thomas A, Geyer H, Schänzer W, Crone C, Kellmann M, Moehring T, Thevis M. 2012. Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer. Anal Bioanal Chem. 403:1279–1289.
  • USFDA. 2001. ‘Guidance for Industry: Bioanalytical Method Validation.’ Available from: www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm070107.pdf
  • Wang Z, Zhang J, Zhang Y. 2009. Detection of eight sedative-hypnotic agents in nutriment products by GC/MS. J Chin Mass Spectrom Soc. 30:282–286.
  • Yan A, Li X, Xi C, Zhang L, Xia S, Wang G, Tang B, Mu Z. 2013. Simultaneous determination of 22 benzodiazepines in Chinese patent drugs and health-care foods by liquid chromatography-tandem mass spectrometry. Chin J Anal Chem. 41:509–516.
  • Yao Y, Li H, Zhang Q, Tian S, Zhang Z. 2007. Determination of illegal mixture in Traditional Chinese Medicine preparations of phenobarbital by HPLC-DAD. Chin Pharm J. 42:224–227.
  • Zhang J, Wang Z, Zhang Y. 2009. Detection of sedative hypnotic drugs in health products by LC-MS/MS. J Chin Mass Spectrom Soc. 30:275–277, 281.
  • Zhu B, Zhao Z, Wang Z, Xue Q, Zhao L. 2010. Analysis of 15 sedatives and soporifics illegally added into functional foods and traditional Chinese medicine preparations by LC-MS/MS. Chin J Pharm Anal. 30:745–751.
  • Zubarev RA, Makarov A. 2013. Orbitrap mass spectrometry. Anal Chem. 85:5288–5296.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.