Pharmacokinetics of tulathromycin in edible tissues of healthy and experimentally infected pigs with Actinobacillus pleuropneumoniae

References

• Agersø H. 2000. Pharmacokinetics and tissue distribution of amoxicillin in healthy and Salmonella typhimurium-inoculated pigs. Am J Vet Res. 61:992–996.
   PubMed Web of Science ®Google Scholar
• Agersø H, Friis C. 1998. Penetration of amoxicillin to the respiratory tract tissues and secretions in Actinobacillus pleuropneumoniae infected pigs. Res Vet Sci. 64:251–257.
   PubMed Web of Science ®Google Scholar
• Anadón A, Gamboa F, Martínez MA, Castellano V, Martínez M, Ares I, Ramos E, Suárez FH, Martínez-Larrañaga MR. 2012. Plasma disposition and tissue depletion of chlortetracycline in the food producing animals, chickens for fattening. Food Chem Toxicol. 50:2714–2721.
   PubMed Web of Science ®Google Scholar
• Anadón A, Martínez MA, Martínez M, Ríos A, Caballero V, Ares I, Martínez-Larrañaga MR. 2008. Plasma and tissue depletion of florfenicol and florfenicol-amine in chickens. J Agric Food Chem. 56:11049–11056.
   PubMed Web of Science ®Google Scholar
• Anadón A, Suárez FH, Martínez MA, Castellano V, Martínez M, Ares I, Ramos E, Gamboa F, Martínez-Larrañaga MR. 2011. Plasma disposition and tissue depletion of difloxacin and its metabolite sarafloxacin in the food producing animals, chickens for fattening. Food Chem Toxicol. 49:441–449.
   PubMed Web of Science ®Google Scholar
• Benchaoui HA, Nowakowski M, Sherington J, Rowan TG, Sunderland SJ. 2004. Pharmacokinetics and lung tissue concentrations of tulathromycin in swine. J Vet Pharmacol Therap. 27:203–210.
   PubMed Web of Science ®Google Scholar
• Bladek T, Posyniak A, Zmudzki J. 2014. Determination of tulathromycin in swine tissues by liquid chromatography-tandem mass spectrometry. Anal Methods. 6:6745–6752.
   Web of Science ®Google Scholar
• Boner PL, Gottschall DW. 2011. Determination and confirmation of tulathromycin residues in bovine liver and porcine kidney via their common hydrolytic fragment using high-performance liquid chromatography/tandem mass spectrometry. J AOAC Int. 94:436–445.
   PubMed Web of Science ®Google Scholar
• Clothier KA, Leavens T, Griffith RW, Wetzlich SE, Baynes RE, Riviere JE, Tell LA. 2011. Pharmacokinetics of tulathromycin after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus). J Vet Pharmacol Therap. 34:448–454.
   PubMed Web of Science ®Google Scholar
• Clothier KA, Leavens T, Griffith RW, Wetzlich SE, Baynes RE, Riviere JE, Tell LA. 2012. Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrus hircus). J Vet Pharmacol Therap. 35:113–120.
   PubMed Web of Science ®Google Scholar
• Cox SR, McLaughlin C, Fielder AE, Yancey MF, Bowersock TL, Garcia-Tapia D, Bryson L, Lucas MJ, Robinson JA, Nanjiani I, et al. 2010. Rapid and prolonged distribution of tulathromycin into lung homogenate and pulmonary epithelial lining fluid of Holstein calves following a single subcutaneous administration of 2.5 mg/kg body weight. Intern J Appl Res Vet Med. 8:129–137.
   Web of Science ®Google Scholar
• Ding H, Wang L, Shen X, Zeng D, Zeng Z. 2013. Plasma and tissue pharmacokinetics of marbofloxacin in experimentally infected chickens with Mycoplasma gallisepticum and Escherichia coli. J Vet Pharmacol Therap. 36:511–515.
   PubMed Web of Science ®Google Scholar
• [EC] European Commission. 2002. Commission Decision 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Commun. L221:8–36.
   Google Scholar
• [EC] European Commission. 2009. Commission Regulation 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Off J Eur Union. L15:1–71.
   Google Scholar
• El-Gendi AYI, Atef M, Amer AMM, Kamel GM. 2010. Pharmacokinetic and tissue distribution of doxycycline in broiler chickens pretreated with either: Diclazuril or halofuginone. Food Chem Toxicol. 48:3209–3214.
   PubMed Web of Science ®Google Scholar
• [EMA] European Medicines Agency. 2014. Opinion of the committee for medicinal products for veterinary use on the establishment of maximum residue limits [Internet]. Committee for Medicinal Products for Veterinary Use. EMA/CVMP/380415/2014. [cited 2015 May 20]. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Maximum-residue-limit_opinion/2015/04/WC500186248.pdf
   Google Scholar
• [EMA] European Medicines Agency. 2015. European public MRL assessment report (EPMAR). Tulathromycin (modification of the microbiological ADI and MRLs in bovine and porcine species) – after provisional maximum residue limits (MRLs). [Internet]. Committee for Medicinal Products for Veterinary Use. EMA/CVMP/380257/2014. [cited 2015 May 20]. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2015/04/WC500185182.pdf
   Google Scholar
• [EMEA] European Medicines Agency. 2004. Tulathromycin. Summary Report (2). [Internet]. Committee for Veterinary Medicinal Products – EMEA/MRL/894/04-Final. [cited 2011 Jul 6]. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Maximum_Residue_Limits_-_Report/2009/11/WC500015754.pdf
   Google Scholar
• Gajda A, Posyniak A, Błądek T. 2013. Analytical procedure for the determination of tulathromycin in swine plasma. Bull Vet Inst Pulawy. 57:191–195.
   Web of Science ®Google Scholar
• Godinho KS, Keane SG, Nanjiani IA, Benchaoui HF, Sunderland SJ. 2005. Minimum inhibitory concentrations of tulathromycin against respiratory bacterial pathogens isolated from clinical cases in European cattle and swine and variability arising from changes in in vitro methodology. Vet Ther. 6:113–121.
   PubMed Web of Science ®Google Scholar
• Grismer B, Rowe JD, Carlson J, Wetzlich SE, Tell LA. 2014. Pharmacokinetics of tulathromycin in plasma and milk samples after a single subcutaneous injection in lactating goats (Capra hircus). J Vet Pharmacol Therap. 37:205–208.
   PubMed Web of Science ®Google Scholar
• Hart FJ, Kilgore RW, Meinert TR, Nutsch RG, Sunderland SJ, Lechtenberg KF. 2006. Efficacy of tulathromycin in the treatment of respiratory disease in pigs caused by Actinobacillus pleuropnemoniae. Vet Rec. 158:433–436.
   PubMed Web of Science ®Google Scholar
• Krist HA. 1997. Macrolide antibiotics in food-animal health. Exp Opin Invest Drugs. 6:103–117.
   PubMedGoogle Scholar
• Letavic MA, Bronk BS, Bertsche CD, Casavant HC, Daniel KL, George DM, Hayashi SF, Kamicker BJ, Kolosko NL, Norcia LJL, et al. 2002. Synthesis and activity of a novel class of tribasic macrocyclic antibiotics: the triamilides. Bioorg Med Chem Lett. 12:2771–2774.
   PubMed Web of Science ®Google Scholar
• Li Y, Zhao N, Zeng Z, Gu X, Fang B, Yang F, Zhang B, Ding H. 2013. Tissue deposition and residue depletion of cyadox and its three major metabolites in pigs after oral administration. J Agric Food Chem. 61:9510–9515.
   PubMed Web of Science ®Google Scholar
• Lindecrona RH, Friis C, Nielsen JP. 2000. Pharmacokinetics and penetration of danofloxacin into the gastrointestinal tract in healthy and in Salmonella typhimurium infected pigs. Res Vet Sci. 68:211–216.
   PubMed Web of Science ®Google Scholar
• Liu JZ, Fung KF, Chen ZL, Zeng ZL, Zhang J. 2002. Tissue pharmacokinetics of florfenicol in pigs experimentally infected with Actinobacillus pleuropneumoniae. Eur J Drug Metab Pharmacokinet. 27:265–271.
   PubMed Web of Science ®Google Scholar
• Monshouwer M, Witkamp RF, Nijmeijer SM, Van Leengoed LAMG, Verheijden JHM, Van Miert ASJPAM. 1995. Infection (Actinobacillus pleuropneumoniae)-mediated suppression of oxidative hepatic drug metabolism and cytochrome P4503A mRNA levels in pigs. Drug Metab Dispos. 23:44–47.
   PubMed Web of Science ®Google Scholar
• Nanjiani IA, McKelvie J, Benchaoui HA, Godinho KS, Sherington J, Sunderland SJ, Weatherley AJ, Rowan TG. 2005. Evaluation of the therapeutic activity of tulathromycin against swine respiratory disease on farms in Europe. Vet Ther. 6:203–213.
   PubMed Web of Science ®Google Scholar
• Nowakowski MA, Inskeep PB, Risk JE, Skogerboe TL, Benchaoui HA, Meinert TR, Sherington J, Sunderland SJ. 2004. Pharmacokinetics and lung tissue concentrations of tulathromycin, a new triamilide antibiotic, in cattle. Vet Ther. 5:60–74.
   PubMed Web of Science ®Google Scholar
• Romanet J, Smith GW, Leavens TL, Baynes RE, Wetzlich SE, Riviere JE, Tell LA. 2012. Pharmacokinetics and tissue elimination of tulathromycin following subcutaneous administration in meat goats. Am J Vet Res. 73:1634–1640.
   PubMed Web of Science ®Google Scholar
• Venner M, Peters J, Höhensteiger N, Schock B, Bornhorst A, Grube M, Adam U, Scheuch E, Weitschies W, Rosskopf D, et al. 2010. Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals. Naunyn Schmiedebergs Arch Pharmacol. 381:161–169.
   PubMed Web of Science ®Google Scholar
• Villarino N, Brown SA, Martín-Jiménez T. 2012. Pharmacokinetics of tulathromycin in healthy and neutropenic mice challenged intranasally with lipopolysaccharide from Escherichia coli. Antimicrob Agents Chemother. 56:4078–4086.
   PubMed Web of Science ®Google Scholar
• Villarino N, Brown SA, Martín-Jiménez T. 2013a. The role of the macrolide tulathromycin in veterinary medicine. Vet J. 198:352–357.
   PubMed Web of Science ®Google Scholar
• Villarino N, Lesman S, Fielder A, García-Tapia D, Cox S, Lucas M, Robinson J, Brown SA, Martín-Jiménez T. 2013b. Pulmonary pharmacokinetics of tulathromycin in swine. Part I: lung homogenate in healthy pigs and pigs challenged intratracheally with lipopolysaccharide of Escherichia coli. J Vet Pharmacol Therap. 36:329–339.
   PubMed Web of Science ®Google Scholar
• Villarino N, Lesman S, Fielder A, García-Tapia D, Cox S, Lucas M, Robinson J, Brown SA, Martín-Jiménez T. 2013c. Pulmonary pharmacokinetics of tulathromycin in swine. Part 2: intra-airway compartments. J Vet Pharmacol Therap. 36:340–349.
   PubMed Web of Science ®Google Scholar
• Wang X, Tao YF, Huang LL, Chen DM, Yin SZ, Ihsan A, Zhou W, Su SJ, Liu ZL, Pan YH, et al. 2012. Pharmacokinetics of tulathromycin and its metabolite in swine administrated with an intravenous bolus injection and a single gavage. J Vet Pharmacol Therap. 35:282–289.
   PubMed Web of Science ®Google Scholar
• Yang F, Huang XH, Li GH, Ni HJ, Zhao YD, Ding HZ, Zeng ZL. 2013. Estimating tulathromycin withdrawal time in pigs using a physiologically based pharmacokinetics model. Food Addit Contam: Part. 30:1255–1263.
   PubMed Web of Science ®Google Scholar
• Young G, Smith GW, Leavens TL, Wetzlich SE, Baynes RE, Mason SE, Riviere JE, Tell LA. 2011. Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats. Res Vet Sci. 90:477–479.
   PubMed Web of Science ®Google Scholar
• Zeng Z, Deng G, Shen X, Rizwan-Ul-Haq M, Zeng D, Ding H. 2011. Plasma and tissue pharmacokinetics of danofloxacin in healthy and in experimentally infected chickens with Pasteurella multocida. J Vet Pharmacol Therap. 34:101–104.
   PubMed Web of Science ®Google Scholar