Advanced search
Publication Cover
Food Additives & Contaminants: Part A Volume 33, 2016 - Issue 6
Submit an article Journal homepage
205
Views
11
CrossRef citations to date
0
Altmetric
Original Articles

Identification of a new tadalafil analogue, dipropylaminopretadalafil, in a dietary supplement

Yen-Chun HuangDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei, Taiwan (R.O.C)View further author information
,
Hui-Chun LeeDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei, Taiwan (R.O.C)Correspondence[email protected]
View further author information
,
Yun-Lian LinDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung, Taiwan (R.O.C)View further author information
,
Chia-Fen TsaiDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei, Taiwan (R.O.C)View further author information
&
Hwei-Fang ChengDivision of Research and Analysis, Taiwan Food and Drug Administration, Taipei, Taiwan (R.O.C)View further author information
Pages 953-958 | Received 27 Feb 2016, Accepted 26 Apr 2016, Published online: 24 May 2016

References

  • Abdel-Aziz AA-M, Asiri YA, El-Azab AS, Al-Omar MA, Kunieda T. 2011. Tadalafil. In: Brittain HG, editor. Profiles of drug substances, excipients, and related methodology. Amsterdam: Elsevier Inc.; p. 287–329.
  • Daugan A, Grondin P, Ruault C, de Gouville A-C, Le M, Coste H, Linget JM, Kirilovsky J, Hyafil F, Labaudinière R. 2003. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. J Med Chem. 46:4533–4542.
  • Hasegawa T, Saijo M, Ishii T, Nagata T, Haishima Y, Kawahara N, Goda Y. 2008. Structural elucidation of a tadalafil analogue found in a dietary supplement. J Food Hyg Soc Jpn (Shokuhin Eiseigaku Zasshi). 49:311–315.
  • Huang Y-C, Lee H-C, Lin Y-L, Li C-Y, Tsai C-F, Cheng H-F. 2016. Separation and identification of a novel tadalafil analogue adulterant in a dietary supplement. Food Addit Contam Part A. 33:179–185.
  • Lin M-C, Liu Y-C, Lin Y-L, Lin J-H. 2009. Identification of a tadalafil analogue adulterated in a dietary supplement. J Food Drug Anal. 17:451–458.
  • Patel DN, Li L, Kee C-L, Ge X, Low M-Y, Koh H-L. 2014. Screening of synthetic PDE-5 inhibitors and their analogues as adulterants: analytical techniques and challenges. J Pharm Biomed Anal. 87:176–190.
  • Toomey VM, Litzau JJ, Flurer CL. 2012. Isolation and structural characterization of two tadalafil analogs found in dietary supplements. J Pharm Biomed Anal. 59:50–57.
  • Zhang G, Yu Y, Wu X, Li J. 2014. Separation and structural elucidation of a new tadalafil analogue diethylaminopretadalafil included as an adulterant in a dietary supplement. J Pharm Biomed Anal. 94:210–214.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.