Screening and quantification of 18 glucocorticoid adulterants from herbal pharmaceuticals and health foods by HPLC and confirmed by LC-Q-TOF-MS/MS

References

• Arthur KE, Wolff J-C, Carrier DJ. 2004. Analysis of betamethasone, dexamethasone and related compounds by liquid chromatography/electrospray mass spectrometry. Rapid Commun Mass Spectrom. 18:678–684.
   PubMed Web of Science ®Google Scholar
• Buscher BAP, Jägfeldt H, Sandman H, Brust-van Schaik R, van Schaik F, Brüll LP. 2012. The determination of budesonide and fluticasone in human sputum samples collected from COPD patients using LC-MS/MS. J Chromatogr B. 880:6–11.
   PubMed Web of Science ®Google Scholar
• Caretti F, Gentili A, Ambrosi A, Rocca LM, Delfini M, Cocco MED, D’Ascenzo G. 2010. Residue analysis of glucocorticoids in bovine milk by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 397:2477–2490.
   PubMed Web of Science ®Google Scholar
• Chen D, Tao Y, Liu Z, Liu Z, Wang Y, Huang L, Yuan Z. 2010. Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of glucocorticoid residues in edible tissues of swine, cattle, sheep, and chicken. Food Addit Contam. 27:1363–1371.
   Web of Science ®Google Scholar
• Cho H-J, Kim JD, Lee W-Y, Chung BC, Choi MH. 2009. Quantitative metabolic profiling of 21 endogenous corticosteroids in urine by liquid chromatography-triple quadrupole-mass spectrometry. Analytica Chimica Acta. 632:101–108.
   PubMed Web of Science ®Google Scholar
• Cui X, Shao B, Zhao R, Yang Y, Hu J, Tu X. 2006. Simultaneous determination of seventeen glucocorticoids residues in milk and eggs by ultraperformance liquid chromatography/electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom. 20:2355–2364.
   PubMed Web of Science ®Google Scholar
• Cuzzola A, Mazzini F, Petri A. 2014. A comprehensive study for the validation of a LC-MS/MS method for the determination of free and total forms of urinary cortisol and its metabolites. J Pham Biomed Anal. 94:203–209.
   PubMed Web of Science ®Google Scholar
• Deceuninck Y, Bichon E, Monteau F, Antignac J-P, Bizec BL. 2011. Determination of MRL regulated corticosteroids in liver from various species using ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC). Analytica Chimica Acta. 700:137–143.
   PubMed Web of Science ®Google Scholar
• Deceunincka Y, Bichona E, Monteaua F, Dervilly-Pinela G, Antignaca JP, Le Bizec B. 2013. Fast and multiresidue determination of twenty glucocorticoids in bovine milk using ultra high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 1294:76–86.
   PubMed Web of Science ®Google Scholar
• Earla R, Boddu SHS, Cholkar K, Hariharan S, Jwala J, Mitra AK. 2010. Development and validation of a fast and sensitive bioanalytical method for the quantitative determination of glucocorticoids-Quantitative measurement of dexamethasone in rabbit ocular matrices by liquid chromatography tandem mass spectrometry. J Pham Biomed Anal. 52:525–533.
   PubMed Web of Science ®Google Scholar
• Ernst E. 2002. Adulteration of Chinese herbal medicines with synthetic drugs: a systematic review. J Intern Med. 252:107–113.
   PubMed Web of Science ®Google Scholar
• Fiori J, Andrisano V. 2014. LC-MS method for the simultaneous determination of six glucocorticoids in pharmaceutical formulations and counterfeit cosmetic products. J Pham Biomed Anal. 91:185–192.
   PubMed Web of Science ®Google Scholar
• Frerichs VA, Tornatore KM. 2004. Determination of the glucocorticoids prednisone, prednisolone, dexamethasone, and cortisol in human serum using liquid chromatography coupled to tandem mass spectrometry. J Chromatogr B. 802:329–338.
   PubMed Web of Science ®Google Scholar
• Gaudiano MC, Lucente D, Antoniella E, Bertocchi P, Muleri N, Manna L, Bartolomei M, Alimonti S, Valvo L, Rodomonte AL. 2010. “For export only” medicines come back to Europe: A RP-LC method for the screening of six glucocorticoids in illegal and counterfeit anti-inflammatory and lightening creams. J Pham Biomed Anal. 53:158–164.
   PubMed Web of Science ®Google Scholar
• Hauser B, Deschner T, Boesch C. 2008. Development of a liquid chromatography–tandem mass spectrometry method for the determination of 23 endogenous steroids in small quantities of primate urine. J Chromatogr B. 862:100–112.
   PubMed Web of Science ®Google Scholar
• Hauwea OVD, Dumoulin F, Antignac JP, Bouche MP, Elliott C, Peteghem CV. 2002. Liquid chromatographic-mass spectrometric analysis of 11 glucocorticoid residues and an optimization of enzymatic hydrolysis conditions in bovine liver. Analytica Chimica Acta. 473:127–134.
   Web of Science ®Google Scholar
• Hauwea OVD, Dumoulina F, Elliottb C, Peteghema CV. 2005. Detection of synthetic glucocorticoid residues in cattle tissue and hair samples after a single dose administration using LC-MS/MS. J Chromatogr B. 817:215–223.
   PubMed Web of Science ®Google Scholar
• Heinig K, Wirz T, Bucheli F. 2008. Determination of glucocorticoids in animal plasma, urine and tissues by column-switching LC–tandem-MS. Chromatographia. 68:689–700.
   Web of Science ®Google Scholar
• Herrero P, Borrull F, Pocurull E, Marcé RM. 2012. Determination of glucocorticoids in sewage and river waters by ultra-high performance liquid chromatography–tandem mass spectrometry. J Chromatogr A. 1224:19–26.
   PubMed Web of Science ®Google Scholar
• Isobe T, Sato K, Joon-Woo K, Tanabe S, Suzuki G, Nakayama K. 2015. Determination of natural and synthetic glucocorticoids in effluent of sewage treatment plants using ultrahigh performance liquid chromatography-tandem mass spectrometry. Environ Sci Pollut Res. 22:14127–14135.
   PubMed Web of Science ®Google Scholar
• Janzen N, Sander S, Terhardt M, Peter M, Sander J. 2008. Fast and direct quantification of adrenal steroids by tandem mass spectrometry in serum and dried blood spots. J Chromatogr B. 861:117–122.
   PubMed Web of Science ®Google Scholar
• Leporati M, Capra P, Cannizzo FT, Biolatti B, Nebbia C, Vincenti M. 2013. Determination of prednisolone metabolites in beef cattle. Food Addit Contam. 30:1044–1054.
   PubMed Web of Science ®Google Scholar
• Li L, Ma P, Wei J, Qian K, Tao L. 2013. LC-ESI-MS method for the determination of dexamethasone acetate in skin of nude mouse. J Chromatogr B. 933:44–49.
   PubMed Web of Science ®Google Scholar
• Malone EM, Elliott CT, Kennedy DG, Regan L. 2010. Screening and quantitative confirmatory method for the analysis of glucocorticoids in bovine milk using liquid chromatography-tandem mass spectrometry. J AOAC Int. 93:1656–1665.
   PubMed Web of Science ®Google Scholar
• Mazzarino M, Botrè F. 2006. A fast liquid chromatographic/mass spectrometric screening method for the simultaneous detection of synthetic glucocorticoids, some stimulants, anti-oestrogen drugs and synthetic anabolic steroids. Rapid Commun Mass Spectrom. 20:3465–3476.
   PubMed Web of Science ®Google Scholar
• Mazzarino M, De La Torre X, Botrè F. 2008. A screening method for the simultaneous detection of glucocorticoids, diuretics, stimulants, anti-oestrogens, beta-adrenergic drugs and anabolic steroids in human urine by LC-ESI-MS/MS. Anal Bioanal Chem. 392:681–698.
   PubMed Web of Science ®Google Scholar
• Methlie P, Hustad S, Kellman R, Almas B, Erichsen MM, Husebye ES, Løvås K. 2013. Multisteroid LC-MS/MS assay for glucocorticoids and androgens and its application in Addison’s disease. Endocr Connect. 2:125–136.
   PubMed Web of Science ®Google Scholar
• Oddone E, Negri S, Bellinzona M, Martino S, Tuccio MD, Grignani E, Cottica D, Imbriani M. 2015. Determination of glucocorticoids in UPLC-MS in environmental samples from an occupational setting. Int J Anal Chem. 1:1–8.
   Web of Science ®Google Scholar
• Park KH, Choi J-H, Abd El-Aty AM, Cho S-K, Park J-H, Kwon KS, Park HR, Kim HS, Shin H-C, Kim MR, et al. 2012. Development of QuEChERS-based extraction and liquid chromatography-tandem mass spectrometry method for quantifying flumethasone residues in beef muscle. Meat Sci. 92:749–753.
   PubMed Web of Science ®Google Scholar
• Park S-J, Kim Y–J, Pyo H–S, Park J. 1990. Analysis of corticosteroids in urine by HPLC and thermospray LC/MS. J Anal Toxicol. 14:102–108.
   PubMed Web of Science ®Google Scholar
• Qin H, Li B, Liu M, Yang Y. 2013a. Separation and pre-concentration of glucocorticoids in water samples by ionic liquid supported vortex-assisted synergic microextraction and HPLC determination. J Sep Sci. 36:1463–1469.
   PubMed Web of Science ®Google Scholar
• Qin H, Qiu X, Zhao J, Liu M, Yang Y. 2013b. Supramolecular solvent-based vortex-mixed microextraction: determination of glucocorticoids in water samples. J Chromatogr A. 1311:11–20.
   PubMed Web of Science ®Google Scholar
• Rönquist-Nii Y, Edlund PO. 2005. Determination of corticosteroids in tissue samples by liquid chromatography–tandem mass spectrometry. J Pham Biomed Anal. 37:341–350.
   PubMed Web of Science ®Google Scholar
• Ruiter AFC, Teeninga N, Nauta J, Endert E, Ackermans MT. 2012. Determination of unbound prednisolone, prednisone and cortisol in human serum and saliva by on-line solid-phase extraction liquid chromatography tandem mass spectrometry and potential implications for drug monitoring of prednisolone and prednisone in saliva. Biomed Chromatogr. 26:789–796.
   PubMed Web of Science ®Google Scholar
• Salem II, Alkhatib M, Najib N. 2011. LC-MS/MS determination of betamethasone and its phosphate and acetate esters in human plasma after sample stabilization. J Pham Biomed Anal. 56:983–991.
   PubMed Web of Science ®Google Scholar
• Samaan GJ, Porquet D, Demelier J–F, Biou D. 1993. Determination of cortisol and associated glucocorticoids in serum and urine by an automated liquid chromatographic assay. Clin Biochem. 26:153–158.
   PubMed Web of Science ®Google Scholar
• Schumacher SB, Hauwe OVD, Peteghem CHV, Naegeli H. 2003. Development of a dual luciferase reporter screening assay for the detection of synthetic glucocorticoids in animal tissues. Analyst. 128:1406–1412.
   PubMed Web of Science ®Google Scholar
• Shibata N, Hayakawa T, Takada K, Hoshino N, Minouchi T, Yamaji A. 1998. Simultaneous determination of glucocorticoids in plasma or urine by high-performance liquid chromatography with precolumn fluorimetric derivatization by 9-anthroyl nitrile. J Chromatogr B. 706:191–199.
   PubMed Web of Science ®Google Scholar
• Tölgyesi Á, Sharma VK, Fekete S, Lukonics D, Fekete J. 2012. Simultaneous determination of eight corticosteroids in bovine tissues using liquid chromatography-tandem mass spectrometry. J Chromatogr B. 906:75–84.
   PubMed Web of Science ®Google Scholar
• Tölgyesi Á, Sharma VK, Kovacsics L, Fekete J. 2010. Quantification of corticosteroids in bovine urine using selective solid phase extraction and reversed-phase liquid chromatography/tandem mass spectrometry. J Chromatogr B. 878:1471–1479.
   PubMed Web of Science ®Google Scholar
• Xu S, Jin PF, Xu QL, Lv XC, He XR. 2015. Advances in the chemical substances illegally adulterated in traditional Chinese medicines and health foods. Chin J New Drugs. 16:1843–1850.
   Google Scholar
• Zhang CY, Chang DL, Chen SL. 2011. Simultaneous determination of five nonsteroidal anti-inflammatory drugs and two glucocorticoids in adulterated Traditional Herbal Medicines for the treatment of rheumatism. Anal Lett. 44:1769–1782.
   Web of Science ®Google Scholar