A reliable, simple and cost-efficient TLC-HPLC method for simultaneously determining florfenicol and florfenicol amine in porcine urine: application to residue surveillance

References

• AL-Shahrani S, Naidoo V. 2015. Florfenicol induces early embryonic death in eggs collected from treated hens. BMC Vet Res. 11:213.
   PubMed Web of Science ®Google Scholar
• Anadón A, Martínez MA, Martínez M, Ríos A, Caballero V, Ares I, Martínez-Larrañaga MR. 2008. Plasma and tissue depletion of florfenicol and florfenicol-amine in chickens. J Agric Food Chem. 56(22):11049–11056.
   PubMed Web of Science ®Google Scholar
• Azzouz A, Ballesteros E. 2012. Gas chromatography-mass spectrometry determination of pharmacologically active substances in urine and blood samples by use of a continuous solid-phase extraction system and microwave-assisted derivatization. J Chromatogr B Analyt Technol Biomed Life Sci. 891–892:12–19.
   PubMed Web of Science ®Google Scholar
• Chen H, Chen H, Ying J, Huang J, Liao L. 2009. Dispersive liquid-liquid microextraction followed by high-performance liquid chromatography as an efficient and sensitive technique for simultaneous determination of chloramphenicol and thiamphenicol in honey. Anal Chim Acta. 632(1):80–85.
   PubMed Web of Science ®Google Scholar
• Chiesa LM, Nobile M, Panseri S, Arioli F. 2017. Antibiotic use in heavy pigs: comparison between urine and muscle samples from food chain animals analysed by HPLC-MS/MS. Food Chem. 235:111–118.
   PubMed Web of Science ®Google Scholar
• European Medicines Agency. 1999. The European Agency for the Evaluation of the Medicinal Products: Florfenicol, (extensionto pigs), summary report, EMEA/MRL/591/99FINAL.
   Google Scholar
• Feng JB, Huang DR, Zhong M, Liu P, Dong JD. 2016. Pharmacokinetics of florfenicol and behaviour of its metabolite florfenicol amine in orange-spotted grouper (Epinephelus coioides) after oral administration. J Fish Dis. 39(7):833–843.
   PubMed Web of Science ®Google Scholar
• Guan S, Lu J, Shen X, Qian W, Liu J, Deng X. 2011a. Florfenicol impairs the immune responses to vaccination against foot-and-mouth disease in mice. Immunopharm Immunot. 33(4):609–613.
   PubMed Web of Science ®Google Scholar
• Guan S, Song Y, Guo W, Wang D, Zhang Z, Lu J, Deng X. 2011b. Immunosuppressive activity of florfenicol on the immune responses in mice. Immunol Invest. 40(4):356–366.
   PubMed Web of Science ®Google Scholar
• Hormazabal V, Steffenak I, Yndestad M. 1993. Simultaneous determination of residues of florfenicol and the metabolite florfenicol amine in fish tissues by high-performance liquid chromatography. J Chromatogr. 616(1):161–165.
   PubMed Web of Science ®Google Scholar
• Horsberg TE, Hoff KA, Nordmo R. 1996. Pharmacokinetics of florfenicol and its metabolite florfenicol amine in atlantic salmon. J Aquat Anim Health. 8(4):292–301.
   Google Scholar
• Hu D, Han Z, Li C, Lv L, Cheng Z, Liu S. 2016. Florfenicol induces more severe hemotoxicity and immunotoxicity than equal doses of chloramphenicol and thiamphenicol in Kunming mice. Immunopharm Immunot. 38:472–485.
   PubMed Web of Science ®Google Scholar
• Hu D, Zhang T, Zhang Z, Wang G, Wang F, Qu Y, Niu Y, Liu S. 2014. Toxicity to the hematopoietic and lymphoid organs of piglets treated with a therapeutic dose of florfenicol. Vet Immunol Immunopathol. 162(3–4):122–131.
   PubMed Web of Science ®Google Scholar
• Khalifeh MS, Amawi MM, Abu-Basha EA, Yonis IB. 2009. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. Poult Sci. 88(10):2118–2124.
   PubMed Web of Science ®Google Scholar
• Li J, Chen H, Chen H, Ye Y. 2012. Selective determination of trace thiamphenicol in milk and honey by molecularly imprinted polymer monolith microextraction and high-performance liquid chromatography. J Sep Sci. 35(1):137–144.
   PubMed Web of Science ®Google Scholar
• Li J, Ding S, Zhang S, Li C, Li X, Liu Z, Liu J, Shen J. 2006. Residue depletion of florfenicol and its metabolite florfenicol amine in Swine tissues after intramuscular administration. J Agric Food Chem. 54(25):9614–9619.
   PubMed Web of Science ®Google Scholar
• Li W, Li Y, Jiang X, Li X, Yu Z. 2018. Compound ammonium glycyrrhizin protects hepatocytes from injury induced by lipopolysaccharide/florfenicol through a mitochondrial pathway. Molecules. 23(9):E2378.
   PubMed Web of Science ®Google Scholar
• [MAPRC] Ministry of Agriculture of the People’s Republic of China. 2003. Announcement NO. 278 of the Ministry of Agriculture. Annex 1. The regulation of withdrawal period for veterinary drugs. Beijing. [accessed 2019 Jun 9]. http://www.moa.gov.cn/nybgb/2003/snqi/201711/t20171126_5919564.html.
   Google Scholar
• [MAPRC] Ministry of Agriculture of the People’s Republic of China. 2017. National food safety standard-maximum residue limits for veterinary drugs in animal derived food (Draft awaiting approved). Beijing. [accessed 2019 Jun 9]. http://down.foodmate.net/info/sort/1/7875.html.
   Google Scholar
• [NRC] National Research Council. 2011. Guide for the care and use of laboratory animals. 8th ed. Washington (DC): National Academies Press.
   Google Scholar
• Palma C, Ramírez J, Benavente A, Cazanga V, Venegas M, Pérez R. 2012. Pharmacokinetics of florfenicol and florfenicol-amine after intravenous administration in sheep. J Vet Pharmacol Ther. 35(5):508–511.
   PubMed Web of Science ®Google Scholar
• Schering-Plough. 1996. Freedom of information summary. Nuflor injectable soution for the treatment of bovine respiratory disease. NADA 141–063.
   Google Scholar
• [DHHS] U.S. Department of Health and Human Services, [FDA] Food and Drug Administration, [CDER] Center for Drug Evaluation and Research, [CVM] Center for Veterinary Medicine. 2001. Guidance for industry, bioanalytical method validation. Rockville (MD); 4–10.
   Google Scholar
• van de Riet JM, Potter RA, Christie-Fougere M, Burns BG. 2003. Simultaneous determination of residues of chloramphenicol, thiamphenicol, florfenicol, and florfenicol amine in farmed aquatic species by liquid chromatography/mass spectrometry. J AOAC Int. 86(3):510–514.
   PubMed Web of Science ®Google Scholar
• Wang H, Wang N, Wang B, Fang H, Fu C, Tang C, Jiang F, Zhou Y, He G, Zhao Q, et al. 2016. Antibiotics detected in urines and adipogenesis in school children. Environ Int. 89–90:204–211.
   PubMed Web of Science ®Google Scholar
• Wei S, Li J, Liu Y, Ma J. 2016. Development of magnetic molecularly imprinted polymers with double templates for the rapid and selective determination of amphenicol antibiotics in water, blood, and egg samples. J Chromatogr A. 1473:19–27.
   PubMed Web of Science ®Google Scholar
• Wrzesinski CL, Crouch LS, Endris R. 2003. Determination of florfenicol amine in channel catfish muscle by liquid chromatography. J AOAC Int. 86(3):515–520.
   PubMed Web of Science ®Google Scholar
• Xie K, Jia L, Yao Y, Xu D, Chen S, Xie X, Pei Y, Bao W, Dai G, Wang J, et al. 2011. Simultaneous determination of thiamphenicol, florfenicol and florfenicol amine in eggs by reversed-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. 879(23):2351–2354.
   PubMed Web of Science ®Google Scholar
• Xie LL, Wu ZX, Chen XX, Li Q, Yuan J, Liu H, Yang Y. 2013. Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in rice field eel (Monopterus albus) after a single-dose intramuscular or oral administration. J Vet Pharmacol Ther. 36(3):229–235.
   PubMed Web of Science ®Google Scholar
• Yang F, Yang F, Kong T, Wang G, Bai D, Liu B. 2018. Pharmacokinetics of florfenicol and its metabolite florfenicol amine in crucian carp (Carassius auratus) at three temperatures after one single intramuscular injection. J Vet Pharmacol Ther. 41(5):739–745.
   PubMed Web of Science ®Google Scholar
• Yao Y, Shao Y, Zhan M, Zou X, Qu W, Zhou Y. 2018. Rapid and sensitive determination of nine bisphenol analogues, three amphenicol antibiotics, and six phthalate metabolites in human urine samples using UHPLC-MS/MS. Anal Bioanal Chem. 410(16):3871–3883.
   PubMed Web of Science ®Google Scholar
• Zhang S, Liu Z, Guo X, Cheng L, Wang Z, Shen J. 2008. Simultaneous determination and confirmation of chloramphenicol, thiamphenicol, florfenicol and florfenicol amine in chicken muscle by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 875(2):399–404.
   PubMed Web of Science ®Google Scholar