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Articles

Fumonisin B1 induced compositional modifications of the renal and hepatic membrane lipids in rats – Dose and exposure time dependence

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Pages 1722-1739 | Received 08 May 2019, Accepted 20 Jul 2019, Published online: 22 Aug 2019

References

  • Abel S, Smuts CM, de Villiers C, Gelderblom WC. 2001. Changes in essential fatty acid patterns associated with normal liver regeneration and the progression of hepatocyte nodules in rat hepatocarcinogenesis. Carcinogenesis. 22:795–804.
  • Bertero A, Moretti A, Spicer L, Caloni F. 2018. Fusarium molds and mycotoxins: potential species-specific effects. Toxins (Basel). 10:244–249.
  • Burger HM, Abel S, Gelderblom WCA. 2018. Modulation of key lipid raft constituents in primary rat hepatocytes by fumonisin B1 - Implications for cancer promotion in the liver. Food Chem Toxicol. 115:34–41.
  • Burger HM, Abel S, Snijman PW, Swanevelder S, Gelderblom WCA. 2007. Altered lipid parameters in hepatic subcellular membrane fractions induced by fumonisin B1. Lipids. 42:249–261.
  • Christie WW. 2003. Lipid analysis : isolation, separation, identification, and structural analysis of lipids. Dundee, Scotland: Oily Press.
  • D’Souza K, Epand RM. 2014. Enrichment of phosphatidylinositols with specific acyl chains. Biochim Biophys Acta - Biomembr. 1838:1501–1508.
  • Dellafiora L, Galaverna G, Dall’Asta C. 2018. Mechanisms of fumonisin B1 toxicity: a computational perspective beyond the ceramide synthases inhibition. Chem Res Toxicol. 31:1203–1212.
  • Fodor J, Meyer K, Riedlberger M, Bauer J, Horn P, Kovacs F, Kovacs M. 2006. Distribution and elimination of fumonisin analogues in weaned piglets after oral administration of Fusarium verticillioides fungal culture. Food Addit Contam. 23:492–501.
  • Folch JM, Leeas M, Sloane-Stanley GH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 226(1):495–509.
  • Gelderblom WC, Smuts CM, Abel S, Snyman SD, Van der Westhuizen L, Huber WW, Swanevelder S. 1997. Effect of fumonisin B1 on the levels and fatty acid composition of selected lipids in rat liver in vivo. Food Chem Toxicol [Internet]. [ cited 2019 Aug 13];35:647–656. doi:10.1016/S0278-6915(97)00036-7
  • Gelderblom WCA, Abel S, Smuts CM, Marnewick J, Marasas WF, Lemmer ER, Ramljak D. 2001. Fumonisin-induced hepatocarcinogenesis: mechanisms related to cancer initiation and promotion. Environ Health Perspect. 109:291–300.
  • Gelderblom WCA, Abel S, Smuts CM, Swanevelder S, Snyman SD. 1999. Regulation of fatty acid biosynthesis as a possible mechanism for the mitoinhibitory effect of fumonisin B1 in primary rat hepatocytes. Prostaglandins, Leukot Essent Fat Acids. 61:225–234.
  • Gelderblom WCA, Moritz W, Swanevelder S, Smuts CM, Abel S. 2002. Lipids and delta6-desaturase activity alterations in rat liver microsomal membranes induced by fumonisin B1. Lipids. 37:869–877.
  • Gelderblom WCA, Snyman SD, Lebepe-Mazur S, van der Westhuizen L, Kriek NP, Marasas WF. 1996. The cancer-promoting potential of fumonisin B1 in rat liver using diethylnitrosamine as a cancer initiator. Cancer Lett. 109:101–108.
  • Hannun YA, Obeid LM. 2008. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 9:139–150.
  • Hiraide T, Ikegami K, Sakaguchi T, Morita Y, Hayasaka T, Masaki N, Waki M, Sugiyama E, Shinriki S, Takeda M, et al. 2016. Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer. Sci Rep. 6:29935.
  • Hulbert AJ. 2005. On the importance of fatty acid composition of membranes for aging. J Theor Biol. 234:277–288.
  • Indiveri C, Iacobazzi V, Tonazzi A, Giangregorio N, Infantino V, Convertini P, Console L, Palmieri F. 2011. The mitochondrial carnitine/acylcarnitine carrier: function, structure and physiopathology. Mol Aspects Med. 32:223–233.
  • Iwase M, Sonoki K, Sasaki N, Ohdo S, Higuchi S, Hattori H, Iida M. 2008. Lysophosphatidylcholine contents in plasma LDL in patients with type 2 diabetes mellitus: relation with lipoprotein-associated phospholipase A2 and effects of simvastatin treatment. Atherosclerosis. 196:931–936.
  • Kang YJ, Alexander JM. 1996. Alterations of the glutathione redox cycle status in fumonisin B1-treated pig kidney cells. J Biochem Toxicol. 11:121–126.
  • Martinez-Larranaga MR, Anadon A, Diaz MJ, Fernandez-Cruz ML, Martinez MA, Frejo MT, Martinez M, Fernandez R, Anton RM, Morales ME, et al. 1999. Toxicokinetics and oral bioavailability of fumonisin B1. Vet Hum Toxicol. 41:357–362.
  • Merrill AH, Sullards MC, Wang E, Voss KA, Riley RT. 2001. Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environ Health Perspect. 109:283–289.
  • Norred WP, Plattner RD, Chamberlain WJ. 1993. Distribution and excretion of [14C]fumonisin B1 in male Sprague-Dawley rats. Nat Toxins. 1:341–346.
  • Raucci FJ, Wijesinghe DS, Chalfant CE, Baumgarten CM. 2010. Exogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes. Cardiovasc Res. 86:55–62.
  • Rheeder JP, Marasas WFO, Vismer HF. 2002. Production of fumonisin analogs by Fusarium species. Appl Environ Microbiol. 68:2101–2105.
  • Riedel S, Abel S, Burger HM, van der Westhuizen L, Swanevelder S, Gelderblom WCA. 2016. Differential modulation of the lipid metabolism as a model for cellular resistance to fumonisin B1–induced cytotoxic effects in vitro. Prostaglandins, Leukot Essent Fat Acids. 109:39–51.
  • Riley RT, Enongene E, Voss KA, Norred WP, Meredith FI, Sharma RP, Spitsbergen J, Williams DE, Carlson DB, Merrill AH. 2001. Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. Environ Health Perspect. 109:301–308.
  • Riley RT, Hinton DM, Chamberlain WJ, Bacon CW, Wang E, Merrill AH, Voss KA. 1994. Dietary fumonisin B1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: a new mechanism of nephrotoxicity. J Nutr. 124:594–603.
  • Sahu SC, Eppley RM, Page SW, Gray GC, Barton CN, O’Donnell MW. 1998. Peroxidation of membrane lipids and oxidative DNA damage by fumonisin B1 in isolated rat liver nuclei. Cancer Lett. 125:117–121.
  • Shephard GS, Thiel PG, Sydenham EW, Alberts JF, Gelderblom WC. 1992. Fate of a single dose of the 14C-labelled mycotoxin, fumonisin B1, in rats. Toxicon. 30:768–770.
  • SPSS (IBM) for Windows. 2012. Chicago (IL, USA): SPSS Inc.
  • Szabó A, Szabó-Fodor J, Fébel H, Mézes M, Balogh K, Bázár G, Kocsó D, Ali O, Kovács M. 2018a. Individual and combined effects of fumonisin B1, deoxynivalenol and zearalenone on the hepatic and renal membrane lipid integrity of rats. Toxins (Basel). 10:4.
  • Szabó A, Szabó-Fodor J, Fébel H, Mézes M, Repa I, Kovács M. 2016. Acute hepatic effects of low-dose fumonisin B1 in rats. Acta Vet Hung. 64:436–448.
  • Szabó A, Szabó-Fodor J, Kachlek M, Mézes M, Balogh K, Glávits R, Ali O, Zeebone Y, Kovács M. 2018b. Dose and exposure time-dependent renal and hepatic effects of intraperitoneally administered fumonisin B1 in rats. Toxins (Basel). 10:465.
  • Vance DE. 2013. Physiological roles of phosphatidylethanolamine N-methyltransferase. Biochim Biophys Acta - Mol Cell Biol Lipids. 1831:626–632.
  • Voss KA, Bacon CW, Norred WP, Chapin RE, Chamberlain WJ, Plattner RD, Meredith FI. 1996. Studies on the reproductive effects of Fusarium moniliforme culture material in rats and the biodistribution of [14C] fumonisin B1 in pregnant rats. Nat Toxins. 4:24–33.
  • Wang E, Norred WP, Bacon CW, Riley RT, Merrill AH. 1991. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J Biol Chem. 266:14486–14490.
  • Weylandt KH, Chiu CY, Gomolka B, Waechter SF, Wiedenmann B. 2012. Omega-3 fatty acids and their lipid mediators: towards an understanding of resolvin and protectin formation. Prostaglandins Other Lipid Mediat. 97:73–82.
  • Yang X, Xu W, Huang K, Zhang B, Wang H, Zhang X, Gong L, Luo Y, He X. 2019. Precision toxicology shows that troxerutin alleviates ochratoxin A–induced renal lipotoxicity. FASEB J. 33:2212–2227.
  • Zhao YY, Chen H, Tian T, Chen DQ, Bai X, Wei F. 2014. A pharmaco-metabonomic study on chronic kidney disease and therapeutic effect of ergone by UPLC-QTOF/HDMS. PLoS One. 9:e115467.
  • Zhao YY, Cheng XL, Wei F, Bai X, Tan XJ, Lin RC, Mei Q. 2013. Intrarenal metabolomic investigation of chronic kidney disease and its TGF-β1 mechanism in induced-adenine rats using UPLC Q-TOF/HSMS/MS. J Proteome Res. 12:692–703.
  • Zhao YY, Wang HL, Cheng XL, Wei F, Bai X, Lin RC, Vaziri ND. 2015. Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis and Nrf2 dysfunction in aristolochic acid-induced nephropathy. Sci Rep. 5:12936.
  • Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sullards MC, et al. 2009. Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals. J Biol Chem. 284:4786–4795.

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