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Articles

Transfer of pyrrolizidine alkaloids from ragwort, common groundsel and viper’s bugloss to milk from dairy cows

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Pages 1906-1921 | Received 24 Jan 2020, Accepted 05 Jul 2020, Published online: 01 Sep 2020

References

  • Bodi D, Ronczka S, Gottschalk C, Behr N, Skibba A, Wagner M, Lahrssen-Wiederholt M, Preiss-Weigert A, These A. 2014. Determination of pyrrolizidine alkaloids in tea, herbal drugs and honey. Food Addit Contam Part A. 31(11):1886–1895. doi:10.1080/19440049.2014.964337.
  • Boppré M, Colegate SM, Edgar J. 2005. Pyrrolizidine Alkaloids of Echium vulgare Honey found in pure pollen. J Agric Food Chem. 53(3):594–600. doi:10.1021/jf0484531.
  • Cone JW, Van Gelder AH, Visscher GJW, Oudshoorn L. 1996. Influence of rumen fluid and substrate concentration on fermentation kinetics measured with a fully automated time related gas production apparatus. Anim Feed Sci Technol. 61(1–4):113–128. doi:10.1016/0377-8401(96)00950-9.
  • Cramer L, Schiebel HM, Ernst L, Beuerle T. 2013. Pyrrolizidine alkaloids in the food chain: development, validation, and application of a new HPLC-ESI-MS/MS sum parameter method. J Agric Food Chem. 61(47):11382–11391. doi:10.1021/jf403647u.
  • Daniel JB, Van Laar H, Warner D, Dijkstra J, Navarro-Villa A, Pellikaan WF. 2014. Passage kinetics of dry matter and neutral detergent fibre through the gastro-intestinal tract of growing beef heifers fed a high-concentrate diet measured with internal d13C and external markers. Anim Prod Sci. 54(9):1471–1475. doi:10.1071/AN14354.
  • de Nijs M, Mulder PPJ, Klijnstra MD, Driehuis F, Hoogenboom LAP. 2017. Fate of pyrrolizidine alkaloids during processing of milk of cows treated with ragwort. Food Addit Contam Part A. 34(12):2212–2219. doi:10.1080/19440049.2017.1364432.
  • Dickinson JO, Cooke MP, King RR, Mohamed PA. 1976. Milk transfer of pyrrolizidine alkaloids in cattle. J Am Vet Med Assoc. 169(11):1192–1196.
  • Dübecke A, Beckh G, Lullmann C. 2011. Pyrrolizidine alkaloids in honey and bee pollen. Food Addit Contam Part A. 28(3):348–358. doi:10.1080/19440049.2010.541594.
  • [EFSA] European Food Safety Authority. 2011. EFSA Panel on Contaminants in the Food Chain (CONTAM). Scientific Opinion on Pyrrolizidine alkaloids in food and feed. Efsa J. 9(11):2406. [134 pp.]. 10.2903/j.efsa.2011.2406
  • [EFSA] European Food Safety Authority. 2017. CONTAM Panel (EFSA Panel on Contaminants in the Food Chain). Statement on the risk for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements. Efsa J. 15:4908. [34 pp.]
  • El-Shazly A, Wink M. 2014. Diversity of pyrrolizidine alkaloids in the Boraginaceae structures, distribution and biological properties. Diversity. 6(2):188–282. doi:10.3390/d6020188.
  • Fu PP, Xia Q, Lin G, Chou MW. 2004. Pyrrolizidine alkaloids - genotoxicity, metabolism, enzymes, metabolic activation, and mechanisms. Drug Metab Rev. 36(1):1–55. doi:10.1081/DMR-120028426.
  • Geburek I, Preiss-Weigert A, Lahrssen-Wiederholt M, Schrenk D, These A. 2020. In vitro metabolism of pyrrolizidine alkaloids – metabolic degradation and GSH conjugate formation of different structure types. Food Chem Toxicol. 135:110868. doi:10.1016/j.fct.2019.110868.
  • He YQ, Yang L, Liu HX, Zhang JW, Liu Y, Fong A, Xiong AZ, Lu YL, Yang L, Wang CH, et al. 2010. Glucuronidation, a new metabolic pathway for pyrrolizidine alkaloids. Chem Res Toxicol. 23(3):591–599. doi:10.1021/tx900328f.
  • Hoogenboom LAP, Mulder PPJ, Zeilmaker MJ, van den Top HJ, Remmelink GJ, Brandon EFA, Klijnstra MD, Meijer GAL, Schothorst R, van Egmond HP. 2011. Carry-over of pyrrolizidine alkaloids from feed to milk in dairy cows. Food Addit Contam. 28(3):359–372. doi:10.1080/19440049.2010.547521.
  • [JECFA] Joint FAO/WHO Expert Committee on Food Additives. 2015. Joint FAO/WHO Expert Committee on Food Additives, eightieth meeting, Rome, 16–25 June. Report TRS 995-JECFA 80/65. http://www.fao.org/fileadmin/user_upload/agns/pdf/jecfa/Summary_report_of_the_80th_JECFA_meeting.pdf. Accessed 2020 Jun 2
  • Kakar F, Akbarian Z, Leslie T, Mustafa ML, Watson J, van Egmond HP, Omar MF, Mofleh J. 2010. An outbreak of hepatic veno-occlusive disease in Western afghanistan associated with exposure to wheat flour contaminated with pyrrolizidine alkaloids. J Toxicol. 313280:1–7. doi:10.1155/2010/313280.
  • Lanigan GW. 1970. Metabolism of pyrrolizidine alkaloids in ovine rumen.2. some factors affecting rate of alkaloid breakdown by rumen fluid in-vitro. Aust J Agric Res. 21(4):633–639. doi:10.1071/AR9700633.
  • Lanigan GW, Smith LW. 1970. Metabolism of pyrrolizidine alkaloids in the ovine rumen. I. Formation of 7-α-hydroxy-1-α-methyl-8-α pyrrolizidine from heliotrine and lasiocarpine. Aust J Agric Res. 21(3):493–500. doi:10.1071/AR9700493.
  • Mädge I, Cramer L, Rahaus I, Jerz G, Winterhalter P, Beuerle T. 2015. Pyrrolizidine alkaloids in herbal teas for infants, pregnant or lactating women. Food Chem. 187:491–498. doi:10.1016/j.foodchem.2015.04.067.
  • Mathon C, Edder P, Bieri S, Christen P. 2014. Survey of pyrrolizidine alkaloids in teas and herbal teas on the Swiss market using HPLC-MS/MS. Anal Bioanal Chem. 406(28):7345–7354. doi:10.1007/s00216-014-8142-8.
  • Mulder PPJ, de Witte SL, Stoopen G, van der Meulen J, Wikselaar P, Gruys E, Groot M, Hoogenboom LAP. 2016. Transfer of pyrrolizidine alkaloids from various herbs to eggs and meat in laying hens. Food Addit Contam Part A. 33(12):1826–1839. doi:10.1080/19440049.2016.1241430.
  • Mulder PPJ, López P, Castellari M, Bodi D, Ronczka S, Preiss-Weigert A, These A. 2018. Occurrence of pyrrolizidine alkaloids in animal- and plant-derived food: results of a survey across Europe. Food Addit Contam Part A. 35(1):118–133. doi:10.1080/19440049.2017.1382726.
  • Picron JF, Herman M, Van Hoeck E, Goscinny S. 2018. Analytical strategies for the determination of pyrrolizidine alkaloids in plant based food and examination of the transfer rate during the infusion process. Food Chem. 266:514–523. doi:10.1016/j.foodchem.2018.06.055.
  • Ruan J, Yang M, Fu P, Ye Y, Lin G. 2014. Metabolic activation of pyrrolizidine alkaloids: insights into the structural and enzymatic basis. Chem Res Toxicol. 27(6):1030–1039. doi:10.1021/tx500071q.
  • Tamminga S, Van Straalen WM, Subnel APJ, Meijer RGM, Steg A, Wever CJG, Blok MC. 1994. The Dutch protein evaluation system: the DVE/OEB-system. Livest Prod Sci. 40(2):139–155. doi:10.1016/0301-6226(94)90043-4.
  • Wang C, Li Y, Gao J, He Y, Xiong A, Yang L, Cheng X, Ma Y, Wang Z. 2011. The comparative pharmacokinetics of two pyrrolizidine alkaloids, senecionine and adonifoline, and their main metabolites in rats after intravenous and oral administration by UPLC/ESIMS. Anal Bioanal Chem. 401(1):275–287. doi:10.1007/s00216-011-5075-3.
  • Wiedenfeld H. 2011. Plants containing pyrrolizidine alkaloids: toxicity and problems. Food Addit Contam. 28(3):282–292. doi:10.1080/19440049.2010.541288.