Dietary exposure of general Chinese population to fatty acid esters of 3-monochloropropane-1, 2-diol (3-MCPD) from edible oils and oil-containing foods

References

• Abraham K, Ke A, Berger-Preiss E, Apel E, Gerling S, Mielke H, Creutzenberg O, Lampen A. 2013. Relative oral bioavailability of 3-MCPD from 3-MCPD fatty acid esters in rats. Arch Toxicol. 87:649–659. doi:10.1007/s00204-012-0970-8.
   PubMed Web of Science ®Google Scholar
• Becalski A, Feng S, Lau BPY, Zhao T. 2015a. A pilot survey of 2- and 3-monochloropropanediol and glycidol fatty acid esters in foods on the Canadian market 2011-2013. J Food Compost Anal. 37:58–66. doi:10.1016/j.jfca.2014.09.002.
   Web of Science ®Google Scholar
• Becalski A, Zhao T, Feng S, Lau BPY. 2015b. A pilot survey of 2- and 3-monochloropropanediol and glycidol fatty acid esters in baby formula on the Canadian market 2012-2013. J Food Compost Anal. 44:111–114. doi:10.1016/j.jfca.2015.08.004.
   Web of Science ®Google Scholar
• Beekman JK, Grassi K, MacMahon S. 2020. Updated occurrence of 3-monochloropropane-1, 2-diol esters (3-MCPD) and glycidyl esters in infant formulas purchased in the United States between 2017 and 2019. Food Addit Contam A. 37(3):374–390. doi:10.1080/19440049.2019.1706002
   Google Scholar
• [CAC] Codex Alimentarius Commission. 2019. Report of the 13rd session of the Codex Committee on Contaminants in foods: Draft code of practice for the reduction of 3-monochloropropane-1,2-diol esters (3-MCPDEs) and glycidyl esters (GEs) in refined oils and food products made with refined oils. Yogyakarta (Indonesia).
   Google Scholar
• Chung HY, Chung SW, Chan BT, Ho YY, Xiao Y. 2013a. Dietary exposure of the Hong Kong adult to fatty acid esters of 3-monochloropropane-1, 2-diol. Food Addit Contam A. 30(9):1508–1512. doi:10.1080/19440049.2013.809628.
   PubMed Web of Science ®Google Scholar
• Chung SW, Chan BT, Chung HY, Xiao Y, Ho YY. 2013b. Occurrence of bound 3-onochloropropan-1,2-diol content in commonly consumed foods in Hong Kong analysed by enzymatic hydrolysis and GC-MS detection. Food Addit Contam A. 30:1248–1254. doi:10.1080/19440049.2013.800996.
   PubMed Web of Science ®Google Scholar
• Craft BD, Chiodini A, Garst J, Granvogl M. 2013. Fatty acid esters of monochloropropanediol (MCPD) and glycidyl in refined edible oils. Food Addit Contam A. 30(1):46–51. doi:10.1080/19440049.2012.709196.
   PubMed Web of Science ®Google Scholar
• Custodio-Mendoza JA, Carro AM, Lage-Yusty MA, Herrero A, Valente IM, Rodrigues JA, Lorenzo RA. 2019. Occurrence and exposure of 3-monochloropropanediol diesters in edible oils and oil-based foodstuffs from the Spanish market. Food Chem. 270:214–222. doi:10.1016/j.foodchem.2018.07.100.
   PubMed Web of Science ®Google Scholar
• Di Campi E, Di Pasquale M, Coni E. 2020. Contamination of some foodstuffs marketed in Italy by fatty acid esters of monochloropropanediols and glycidol. Food Addit Contam A. 37(5):753–762. doi:10.1080/19440049.2020.1725146
   Google Scholar
• [EFSA CONTAM Panel] European Food Safety Authority Panel on Contaminants in the Food Chain. 2016. Risks for human health related to the presence of 3- and 2- monochloropropanediol (MCPD), and their fatty acid esters, and glycidyl fatty acid esters in food. Efsa J. 14(5):4426.
   Web of Science ®Google Scholar
• [EFSA CONTAM Panel] European Food Safety Authority Panel on Contaminants in the Food Chain. 2018. Scientific opinion on the update of the risk assessment on 3-monochloropropane diol and its fatty acid esters. Efsa J. 16(1):5083.
   Google Scholar
• Gao B, Liu M, Huang G, Zhang Z, Zhao Y, Wang T, Zhang Y, Liu J, Yu L. 2017. Absorption, distribution, metabolism and excretion of 3-MCPD 1-monopalmitate after oral administration in rats. J Agric Food Chem. 65(12):2609–2614. doi:10.1021/acs.jafc.7b00639.
   PubMed Web of Science ®Google Scholar
• Hamlet CG, Asuncion L, Velisek J, Dolezal M, Zelinkova Z, Crews C. 2011. Formation and occurrence of esters of 3-chloropropane-1,2-(3-CPD) in foods: what we know and what we assume. Eur J Lipid Sci Technol. 113:279–303. doi:10.1002/ejlt.201000480.
   Web of Science ®Google Scholar
• Hew KS, Asis AJ, Tan TB, Yusoff MM, Lai OM, Nehdi IA, Tan CP. 2020. Revising degumming and bleaching processes of palm oil refining for the mitigation of 3-monochloropropane-1, 2-diol esters (3-MCPDE) and glycidyl esters (GE) content in refined palm oil. Food Chem. 307:125545. doi:10.1016/j.food.chem.2019.125545
   PubMed Web of Science ®Google Scholar
• Hrncirik K, Van Duijn G. 2011. An initial study on the formation of 3-MCPD esters during oil refining. Eur J Lipid Sci Technol. 113:374–379. doi:10.1002/ejlt.201000317.
   Web of Science ®Google Scholar
• Huang GR, Gao BY, Xue JL, Cheng ZH, Sun XJ, Zhang YQ, Yu LL. 2018. Toxicokinetics and metabolism of 3-monochloropropane 1,2-diol (3-MCPD) dipalmitate in Sprague Dawley rats. J Agric Food Chem. 66(44):11672–11680. doi:10.1021/acs.jafc.B05422.
   PubMed Web of Science ®Google Scholar
• Ikeda N, Fujii K, Sarada M, Saito H, Kawabata M, Naruse K, Yuki K, Nakagiri H, Honda H, Tamaki Y. 2012. Genotoxicity studies of glycidol fatty acid ester (glycidol linoleate) and glycidol. Food Chem Toxicol. 50:3927–3933. doi:10.1016/j.fct.2012.08.022.
   PubMed Web of Science ®Google Scholar
• [JECFA] Joint FAO/WHO Expert Committee on Food Additives. 2017. Evaluation of certain contaminants in food (Eighty-third report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No.1002.
   Google Scholar
• Kuhlmann J. 2019. 2-mnochloropropanediol(2-MCPD), 3-monochloropropanediol (3-MCPD), and glycidol in infant and adult/pediatric nutritional formula: single-laboratory validation, first action 2018. 12. J AOAC Int. 102(4):1205–1220. doi:10.5740/jaoacint.19-0026.
   PubMed Web of Science ®Google Scholar
• Leigh JK, MacMahon S. 2017. Occurrence of 3-monochloropropanediol esters and glycidyl esters in commercial infant formulas in the United States. Food Addit Contam A. 34:356–370. doi:10.1080/19440049.2016.1276304.
   PubMed Web of Science ®Google Scholar
• Li C, Nie SP, Zhou YQ, Xie MY. 2015. Exposure assessment of 3-monochloropropane-1, 2-diol esters from edible oils and fats in China. Food ChemToxi. 75:8–13. doi:10.1016/j.fct.2014.10.003.
   Google Scholar
• Li C, Zhou YQ, Zhu JP, Wang SN, Nie SP, Xie MY. 2016. Formation of 3-chloropropane-1,2-diol esters in model systems simulating thermal processing of edible oil. LWT-Food Sci Techol. 69:586–592. doi:10.1016/j.lwt.2016.02.012.
   Web of Science ®Google Scholar
• Li J, Wang S, Wang M, Shi W, Du X, Sun C. 2013a. The toxicity of 3-chloropropane-1, 2-dipalmitate in Wistar rats and a metabonomics analysis of rat urine by ultra-performance liquid chromatography-mass spectrometry. Chem Biol Interact. 206:337–345. doi:10.1016/j.cbi.2013.10.004.
   PubMed Web of Science ®Google Scholar
• Li N, Fang QM, Yan XB, Zheng KC, Lin GM, Fu WS. 2013b. Survey of pollution of fatty acid of chloropropanols in edible vegetable oils in the retail in China. J Chin Cereal Oil Assoc. 28(8):28–32.
   Google Scholar
• Liu Q, Han F, Xie K, Miao H, Wu YN. 2013. Simultaneous determination of total fatty acid esters of chloropropanols in edible oils by gas chromatography-mass spectrometry with solid-supported liquid-liquid extraction. J Chromatogr A. 1314:208–215. doi:10.1016/j.chroma.2013.08.074.
   PubMed Web of Science ®Google Scholar
• MacMahon S, Begley TH, Diachenko GW. 2013. Occurrence of 3-MCPD and glycidyl esters in edible oils in the United States. Food Addit Contam A. 30(12):2081–2092. doi:10.1080/19440049.2013.840805.
   PubMed Web of Science ®Google Scholar
• Onami S, Cho YM, Toyoda T, Akagi J-I, Fujiwara S, Ochiai R, Tsujino K, Nishikawa A, Ogawa K. 2015. Orally administered glycidol and its fatty acid esters as well as 3-MCPD fatty acid esters are metabolised to 3-MCPD in the F344 rat. Regul Toxicol Pharmacol. 73:726–731. doi:10.1016/j.yrtph.2015.10.020.
   PubMed Web of Science ®Google Scholar
• Onami S, Cho YM, Toyoda T, Mizuta Y, Yoshida M, Nishikawa A, Ogawa K. 2014. A 13-week repeated dose study of three 3-monochloropropane-1,2-diol fatty acid esters in F344 rats. Arch Toxicol. 88:871–880. doi:10.1007/s00204-013-1190-6.
   PubMed Web of Science ®Google Scholar
• Pudel F, Benecke P, Fehling P, Freudenstein A, Matthäus B, Schwaf A. 2011. On the necessity of edible oil refining and possible sources of 3-MCPD and glycidyl esters. Eur J Lipid Sci Technol. 113:368–373. doi:10.1002/ejlt.201000460.
   Web of Science ®Google Scholar
• [WHO] World Health Organization. 1995. Second workshop on reliable evaluation of low-level contamination of food[R]. Kulmbach (Germany): Rome.
   Google Scholar
• Xiang XL. 2018. Detection and exposure assessment of 3-MCPD ester in edible oils and optimization of refine process of camellia oil [D]. Hang zhou (China): Zhejiang University.
   Google Scholar
• Zulkurnain M, Lai OM, Tan SC, Abdul Latip R, Tan CP. 2013. Optimization of palm oil physical refining process for reduction of 3-monochloropropane-1,2-diol (3-MCPD) ester formation. J Agric Food Chem. 61(13):3341–3349. doi:10.1021/jf4009185.
   PubMed Web of Science ®Google Scholar