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Nuclear mechanotransduction: Forcing the nucleus to respond

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Pages 19-22 | Received 01 Oct 2014, Accepted 12 Dec 2014, Published online: 04 Mar 2015

References

  • Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell 2006; 126:677-89; PMID:16923388; http://dx.doi.org/10.1016/j.cell.2006.06.044
  • Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005; 8:241-54; PMID:16169468; http://dx.doi.org/10.1016/j.ccr.2005.08.010
  • Discher DE, Janmey P, Wang Y-L. Tissue cells feel and respond to the stiffness of their substrate. Science 2005; 310:1139-43; PMID:16293750; http://dx.doi.org/10.1126/science.1116995
  • Hoffman BD, Grashoff C, Schwartz MA. Dynamic molecular processes mediate cellular mechanotransduction. Nature 2011; 475:316-23; PMID:21776077; http://dx.doi.org/10.1038/nature10316
  • Smutny M, Yap AS. Neighborly relations: cadherins and mechanotransduction. J. Cell Biol 2010; 189:1075-7; PMID:20584914; http://dx.doi.org/10.1083/jcb.201005151
  • Hervy M, Hoffman L, Beckerle MC. From the membrane to the nucleus and back again: bifunctional focal adhesion proteins. Curr Opin Cell Biol 2006; 18:524-32; PMID:16908128; http://dx.doi.org/10.1016/j.ceb.2006.08.006
  • Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, et al. Role of YAP/TAZ in mechanotransduction. Nature 2011; 474:179-83; PMID:21654799; http://dx.doi.org/10.1038/nature10137
  • Wang N, Tytell JD, Ingber DE. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol 2009; 10:75-82; PMID:19197334; http://dx.doi.org/10.1038/nrm2594
  • Bissell MJ, Hall HG, Parry G. How does the extracellular matrix direct gene expression? J Theor Biol 1982; 99:31-68; PMID:6892044; http://dx.doi.org/10.1016/0022-5193(82)90388-5
  • Guilluy C, Osborne LD, Van Landeghem L, Sharek L, Superfine R, Garcia-Mata R, Burridge K. Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus. Nat Cell Biol 2014; 16:376-81; PMID:24609268; http://dx.doi.org/10.1038/ncb2927
  • Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, et al. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 2013; 341:1240104; PMID:23990565; http://dx.doi.org/10.1126/science.1240104
  • Morris NR. Nuclear positioning: the means is at the ends. Curr Opin Cell Biol 2003; 15:54-9; PMID:12517704; http://dx.doi.org/10.1016/S0955-0674(02)00004-2
  • Gundersen GG, Worman HJ. Nuclear positioning. Cell 2013; 152:1376-89; PMID:23498944; http://dx.doi.org/10.1016/j.cell.2013.02.031
  • Starr DA, Han M. Role of ANC-1 in tethering nuclei to the actin cytoskeleton. Science 2002; 298:406-9; PMID:12169658; http://dx.doi.org/10.1126/science.1075119
  • Crisp M, Liu Q, Roux K, Rattner JB, Shanahan C, Burke B, Stahl PD, Hodzic D. Coupling of the nucleus and cytoplasm: role of the LINC complex. J Cell Biol 2006; 172:41-53; PMID:16380439; http://dx.doi.org/10.1083/jcb.200509124
  • Khatau, S. B., Hale CM, Stewart-Hutchinson PJ, Patel MS, Stewart CL, Searson PC, Hodzic D, Wirtz D. A perinuclear actin cap regulates nuclear shape. Proc Natl Acad Sci U S A 2009; 106:19017-22; PMID:19850871; http://dx.doi.org/10.1073/pnas.0908686106
  • Luxton GWG, Starr DA. KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus. Curr Opin Cell Biol 2014; 28:69-75; PMID:24704701; http://dx.doi.org/10.1016/j.ceb.2014.03.002
  • Dahl KN, Kalinowski A. Nucleoskeleton mechanics at a glance. J Cell Sci 2011; 124:675-8; PMID:21321324; http://dx.doi.org/10.1242/jcs.069096
  • Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M. SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron 2009; 64:173-87; PMID:19874786; http://dx.doi.org/10.1016/j.neuron.2009.08.018
  • Petrie RJ, Koo H, Yamada KM. Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix. Science 2014; 345:1062-5; PMID:25170155; http://dx.doi.org/10.1126/science.1256965
  • Turgay Y, Champion L, Balazs C, Held M, Toso A, Gerlich DW, Meraldi P, Kutay U. SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J. Cell Biol 2014; 204:1099-109; PMID:24662567; http://dx.doi.org/10.1083/jcb.201310116
  • Maniotis AJ, Chen CS, Ingber DE. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A 1997; 94:849-54; PMID:9023345; http://dx.doi.org/10.1073/pnas.94.3.849
  • Lombardi,ML, Jaalouk DE, Shanahan CM, Burke B, Roux KJ, Lammerding J. The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. J Biol Chem 2011; 286:26743-53; PMID:21652697; http://dx.doi.org/10.1074/jbc.M111.233700
  • Guilak F. Compression-induced changes in the shape and volume of the chondrocyte nucleus. J Biomech 1995; 28:1529-41; PMID:8666592; http://dx.doi.org/10.1016/0021-9290(95)00100-X
  • Anno T, Sakamoto N, Sato M. Role of nesprin-1 in nuclear deformation in endothelial cells under static and uniaxial stretching conditions. Biochem Biophys Res Commun 2012; 424:94-9; PMID:22728879; http://dx.doi.org/10.1016/j.bbrc.2012.06.073
  • Booth-Gauthier EA, Alcoser TA, Yang G, Dahl KN. Force-induced changes in subnuclear movement and rheology. Biophys J 2012; 103:2423-31; PMID:23260044; http://dx.doi.org/10.1016/j.bpj.2012.10.039
  • Isermann P, Lammerding J. Nuclear mechanics and mechanotransduction in health and disease. Curr Biol CB 2013; 23:R1113-21; PMID:24355792; http://dx.doi.org/10.1016/j.cub.2013.11.009
  • Lammerding J, Schulze PC, Takahashi T, Kozlov S, Sullivan T, Kamm RD, Stewart CL, Lee RT. Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. J Clin Invest 2004; 113:370-8; PMID:14755334; http://dx.doi.org/10.1172/JCI200419670
  • Luxton GWG, Gomes ER, Folker ES, Vintinner E, Gundersen GG. Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement. Science 2010; 329:956-9; PMID:20724637; http://dx.doi.org/10.1126/science.1189072
  • Deguchi S, Maeda K, Ohashi T, Sato M. Flow-induced hardening of endothelial nucleus as an intracellular stress-bearing organelle. J Biomech 2005; 38:1751-9; PMID:16005465; http://dx.doi.org/10.1016/j.jbiomech.2005.06.003
  • Philip JT, Dahl KN. Nuclear mechanotransduction:response of the lamina to extracellular stress with implications in aging. J Biomech 2008; 41:3164-70; PMID:18945430; http://dx.doi.org/10.1016/j.jbiomech.2008.08.024
  • Ho CY, Jaalouk DE, Vartiainen MK, Lammerding J. Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics. Nature 2013; 497:507-11; PMID:23644458; http://dx.doi.org/10.1038/nature12105
  • Bertrand AT, Ziaei S, Ehret C, Duchemin H, Mamchaoui K, Bigot A, Mayer M, Quijano-Roy S, Desguerre I, Lainé J, et al. Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors. J Cell Sci 2014; 127:2873-84; PMID:24806962; http://dx.doi.org/10.1242/jcs.144907
  • Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, et al. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 2010; 466:263-6; PMID:20613844; http://dx.doi.org/10.1038/nature09198
  • Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol CB 2013; 23:1024-30; PMID:23684974; http://dx.doi.org/10.1016/j.cub.2013.04.049
  • Simon DN, Wilson KL. The nucleoskeleton as a genome-associated dynamic ‘network of networks’. Nat Rev Mol Cell Biol 2011; 12:695-708; PMID:21971041; http://dx.doi.org/10.1038/nrm3207
  • Poh Y-C, Shevtsov SP, Chowdhury F, Wu DC, Na S, Dundr M, Wang N. Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells. Nat Commun 2012; 3:866; PMID:22643893; http://dx.doi.org/10.1038/ncomms1873
  • Sawada, Y., Tamada M, Dubin-Thaler BJ, Cherniavskaya O, Sakai R, Tanaka S, Sheetz MP. Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell 2006; 127:1015-26; PMID:17129785; http://dx.doi.org/10.1016/j.cell.2006.09.044