914
Views
8
CrossRef citations to date
0
Altmetric
Extra View

The cohesin complex prevents the end-joining of distant DNA double-strand ends in S phase: Consequences on genome stability maintenance

, &
Pages 339-345 | Received 30 Mar 2016, Accepted 20 May 2016, Published online: 03 Aug 2016

References

  • Guirouilh-Barbat J, Lambert S, Bertrand P, Lopez BS. Is homologous recombination really an error-free process? Front Genet 2014; 5:175; PMID:24966870; http://dx.doi.org/10.3389/fgene.2014.00175
  • Bétermier M, Bertrand P, Lopez BS. Is Non-Homologous End-Joining Really an Inherently Error-Prone Process? PLoS Genet 2014; 10:e1004086; http://dx.doi.org/10.1371/journal.pgen.1004086
  • Deriano L, Roth DB. Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage. Annu Rev Genet 2013; 47:433-55; PMID:24050180; http://dx.doi.org/10.1146/annurev-genet-110711-155540
  • Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol 2003; 23:5706-15; PMID:12897142; http://dx.doi.org/10.1128/MCB.23.16.5706-5715.2003
  • Guirouilh-Barbat J, Huck S, Lopez BS. S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining. Oncogene 2008; 27:1726-36; PMID:17891177; http://dx.doi.org/10.1038/sj.onc.1210807
  • Caron P, Aymard F, Iacovoni JS, Briois S, Canitrot Y, Bugler B, Massip L, Losada A, Legube G. Cohesin protects genes against ??H2AX induced by DNA double-strand breaks. PLoS Genet 2012; 8:e1002460.
  • Sofueva S, Yaffe E, Chan WC, Georgopoulou D, Vietri Rudan M, Mira-Bontenbal H, Pollard SM, Schroth GP, Tanay A, Hadjur S. Cohesin-mediated interactions organize chromosomal domain architecture. EMBO J 2013; 321:3119–29; 1-11; PMID:23211745
  • Deng Z, Wang Z, Stong N, Plasschaert R, Moczan A, Chen HS, Hu S, Wikramasinghe P, Davuluri RV, Bartolomei MS, et al. A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J 2012; 31:4165-78; PMID:23010778; http://dx.doi.org/10.1038/emboj.2012.266
  • Musio A, Montagna C, Mariani T, Tilenni M, Focarelli ML, Brait L, Indino E, Benedetti PA, Chessa L, Albertini A, et al. SMC1 involvement in fragile site expression. Hum Mol Genet 2005; 14:525-33; PMID:15640246; http://dx.doi.org/10.1093/hmg/ddi049
  • Gelot C, Guirouilh-Barbat J, Le Guen T, Dardillac E, Chailleux C, Canitrot Y, Lopez BS. The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends. Mol Cell 2016; 61:15-26; PMID:26687679; http://dx.doi.org/10.1016/j.molcel.2015.11.002
  • Soutoglou E, Dorn JF, Sengupta K, Jasin M, Nussenzweig A, Ried T, Danuser G, Misteli T. Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol 2007; 9:675-82; PMID:17486118; http://dx.doi.org/10.1038/ncb1591
  • Klein F, Mahr P, Galova M, Buonomo SB, Michaelis C, Nairz K, Nasmyth K. A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis. Cell 1999; 98:91-103; PMID:10412984; http://dx.doi.org/10.1016/S0092-8674(00)80609-1
  • Tittel-Elmer M, Lengronne A, Davidson MB, Bacal J, François P, Hohl M, Petrini JH, Pasero P, Cobb JA. Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell 2012; 48:98-108; PMID:22885006; http://dx.doi.org/10.1016/j.molcel.2012.07.004
  • Potts PR, Porteus MH, Yu H. Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J 2006; 25:3377-88; PMID:16810316; http://dx.doi.org/10.1038/sj.emboj.7601218
  • Dion V, Kalck V, Seeber A, Schleker T, Gasser SM. Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. EMBO Rep 2013; 14:984-91; PMID:24018421; http://dx.doi.org/10.1038/embor.2013.142
  • Jeppsson K, Kanno T, Shirahige K, Sjögren C. The maintenance of chromosome structure: positioning and functioning of SMC complexes. Nat Rev Mol Cell Biol 2014; 15:601-14; PMID:25145851; http://dx.doi.org/10.1038/nrm3857
  • Guillou E, Ibarra A, Coulon V, Casado-Vela J, Rico D, Casal I, Schwob E, Losada A, Méndez J. Cohesin organizes chromatin loops at DNA replication factories. Genes Dev 2010; 24:2812-22; PMID:21159821; http://dx.doi.org/10.1101/gad.608210
  • Guacci V, Koshland D, Strunnikov aV. A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae 1997; 91:47-57
  • Saintigny Y. Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J 2001; 20:3861-3870; PMID:11447127; http://dx.doi.org/10.1093/emboj/20.14.3861
  • Couedel C, Mills KD, Barchi M, Shen L, Olshen A, Johnson RD, Nussenzweig A, Essers J, Kanaar R, Li GC, et al. Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes Dev 2004; 18:1293-1304; PMID:15175261; http://dx.doi.org/10.1101/gad.1209204
  • Mills KD, Ferguson DO, Essers J, Eckersdorff M, Kanaar R, Alt FW. Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. Genes Dev 2004; 18:1283-92; PMID:15175260; http://dx.doi.org/10.1101/gad.1204304
  • Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsu M, Pilch DR, et al. AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching. Nature 2001; 414:660-5; PMID:11740565; http://dx.doi.org/10.1038/414660a
  • Desiderio S. Temporal and spatial regulatory functions of the V(D)J recombinase. Semin Immunol 2010; 22:362-69; PMID:21036059; http://dx.doi.org/10.1016/j.smim.2010.09.001
  • Schrader CE, Guikema JEJ, Linehan EK, Selsing E, Stavnezer J. Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. J Immunol 2007; 179:6064-71; PMID:17947680; http://dx.doi.org/10.4049/jimmunol.179.9.6064
  • Enervald E, Du L, Visnes T, Björkman A, Lindgren E, Wincent J, Borck G, Colleaux L, Cormier-Daire V, van Gent DC, et al. A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination. J Exp Med 2013; 210:2503-13; PMID:24145515; http://dx.doi.org/10.1084/jem.20130168
  • Thomas-Claudepierre A-S, Schiavo E, Heyer V, Fournier M, Page A, Robert I, Reina-San-Martin B. The cohesin complex regulates immunoglobulin class switch recombination. J Exp Med 2013; 210:2495-502; PMID:24145512; http://dx.doi.org/10.1084/jem.20130166

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.