Keumsa Linteusan suppresses invasion of cancer cells through the inhibition of cellular adhesion and MMP‐9 expression

References

• Bae , E , Kim , WJ , Kang , YM , Suk , K , Koh , EM , Cha , HS , Ahn , KS , Huh , TL and Lee , WH . 2007 . Glucocorticoid‐induced tumour necrosis factor receptor‐related protein‐mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis . Clin Exp Immunol , 148 : 410 – 418 .
   PubMed Web of Science ®Google Scholar
• Collins , L , Zhu , T , Guo , J , Xiao , ZJ and Chen , CY . 2006 . Phellinus linteus sensitises apoptosis induced by doxorubicin in prostate cancer . British J Cancer , 95 : 282 – 288 .
   PubMed Web of Science ®Google Scholar
• Dai , D , Chen , J and Xu , L . 1997 . [Quantitative analysis of E‐cadherin expression and clinicopathologic evaluation in gastric cancer] . Zhonghua Yi Xue Za Zhi , 77 : 668 – 671 .
   PubMedGoogle Scholar
• Fullerton , SA , Samadi , AA , Tortorelis , DG , Choudhury , MS , Mallouh , C , Tazaki , H and Konno , S . 2000 . Induction of apoptosis in human prostatic cancer cells with beta‐glucan (Maitake mushroom polysaccharide) . Molecular Urology , 4 : 7 – 13 .
   PubMedGoogle Scholar
• Gentilini , D , Busacca , M , Di Francesco , S , Vignali , M , Vigano , P and Di Blasio , AM . 2007 . PI3K/Akt and ERK1/2 signalling pathways are involved in endometrial cell migration induced by 17beta‐estradiol and growth factors . Molecular Human Reproduction , 13 : 317 – 322 .
   PubMed Web of Science ®Google Scholar
• Guo , J , Zhu , T , Collins , L , Xiao , ZX , Kim , SH and Chen , CY . 2007 . Modulation of lung cancer growth arrest and apoptosis by Phellinus Linteus . Molecular Carcinogenesis , 46 : 144 – 154 .
   PubMed Web of Science ®Google Scholar
• Han , SB , Lee , CW , Jeon , YJ , Hong , ND , Yoo , ID , Yang , KH and Kim , HM . 1999 . The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis . Immunopharmacology , 41 : 157 – 164 .
   PubMed Web of Science ®Google Scholar
• Hannigan , G , Troussard , AA and Dedhar , S . 2005 . Integrin‐linked kinase: a cancer therapeutic target unique among its ILK . Nature Reviews , 5 : 51 – 63 .
   Web of Science ®Google Scholar
• Hsieh , TC and Wu , JM . 2001 . Cell growth and gene modulatory activities of Yunzhi (Windsor Wunxi) from mushroom Trametes versicolor in androgen‐dependent and androgen‐insensitive human prostate cancer cells . International J Oncology , 18 : 81 – 88 .
   PubMed Web of Science ®Google Scholar
• Karin , M and Greten , FR . 2005 . NF‐kappaB: linking inflammation and immunity to cancer development and progression . Nat Rev Immunol , 5 : 749 – 759 .
   PubMed Web of Science ®Google Scholar
• Kato , R , Ishikawa , T , Kamiya , S , Oguma , F , Ueki , M , Goto , S , Nakamura , H , Katayama , T and Fukai , F . 2002 . A new type of antimetastatic peptide derived from fibronectin . Clin Cancer Res , 8 : 2455 – 2462 .
   PubMed Web of Science ®Google Scholar
• Kim , BC , Choi , JW , Hong , HY , Lee , SA , Hong , S , Park , EH , Kim , SJ and Lim , CJ . 2006a . Heme oxygenase‐1 mediates the anti‐inflammatory effect of mushroom Phellinus linteus in LPS‐stimulated RAW264.7 macrophages . J Ethnopharmacology , 106 : 364 – 371 .
   PubMed Web of Science ®Google Scholar
• Kim , GY , Oh , YH and Park , YM . 2003a . Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide‐mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C . Biochemical and Biophysical Research Communications , 309 : 399 – 407 .
   PubMed Web of Science ®Google Scholar
• Kim , GY , Park , SK , Lee , MK , Lee , SH , Oh , YH , Kwak , JY , Yoon , S , Lee , JD and Park , YM . 2003b . Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase . International Immunopharmacology , 3 : 1281 – 1292 .
   PubMed Web of Science ®Google Scholar
• Kim , WJ , Bae , EM , Kang , YJ , Bae , HU , Hong , SH , Lee , J , Park , JE , Kwon , BS , Suk , K and Lee , WH . 2006b . Glucocorticoid‐induced TNFR family‐related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques . Immunology , 119 : 421 – 429 .
   PubMed Web of Science ®Google Scholar
• Kim , WJ and Lee , WH . 2004 . LIGHT is expressed in foam cells and involved in destabilization of atherosclerotic plaques through induction of matrix metalloproteinase‐9 and IL‐8 . Immune Network , 4 : 116 – 122 .
   Google Scholar
• Lee , WH , Kim , SH , Lee , Y , Lee , BB , Kwon , B , Song , H , Kwon , BS and Park , JE . 2001 . Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases . Arteriosclerosis, Thrombosis, and Vascular Biology , 21 : 2004 – 2010 .
   PubMed Web of Science ®Google Scholar
• Li , G , Kim , DH , Kim , TD , Park , BJ , Park , HD , Park , JI , Na , MK , Kim , HC , Hong , ND Lim , K. 2004 . Protein‐bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells . Cancer Letters , 216 : 175 – 181 .
   PubMed Web of Science ®Google Scholar
• Maeda , S and Omata , M . 2008 . Inflammation and cancer: role of nuclear factor‐kappaB activation . Cancer science , 99 : 836 – 842 .
   PubMed Web of Science ®Google Scholar
• Park , SK , Kim , GY , Lim , JY , Kwak , JY , Bae , YS , Lee , JD , Oh , YH , Ahn , SC and Park , YM . 2003 . Acidic polysaccharides isolated from Phellinus linteus induce phenotypic and functional maturation of murine dendritic cells . Biochemical and Biophysical Research Communications , 312 : 449 – 458 .
   PubMed Web of Science ®Google Scholar
• Playford , MP and Schaller , MD . 2004 . The interplay between Src and integrins in normal and tumor biology . Oncogene , 23 : 7928 – 7946 .
   PubMed Web of Science ®Google Scholar
• Sasaki , T , Arai , Y , Ikekawa , T , Chihara , G and Fukuoka , F . 1971 . Antitumor polysaccharides from some polyporaceae, Ganoderma applanatum (Pers.) Pat and Phellinus linteus (Berk. et Curt) Aoshima . Chemical & Pharmaceutical Bulletin , 19 : 821 – 826 .
   PubMed Web of Science ®Google Scholar
• Saxena , NK , Sharma , D , Ding , X , Lin , S , Marra , F , Merlin , D and Anania , FA . 2007 . Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin‐mediated promotion of invasion and migration of hepatocellular carcinoma cells . Cancer Research , 67 : 2497 – 2507 .
   PubMed Web of Science ®Google Scholar
• Schwartsburd , PM . 2003 . Chronic inflammation as inductor of pro‐cancer microenvironment: pathogenesis of dysregulated feedback control . Cancer Metastasis Reviews , 22 : 95 – 102 .
   PubMed Web of Science ®Google Scholar
• Sethi , G , Sung , B and Aggarwal , BB . 2008 . TNF: a master switch for inflammation to cancer . Front Biosci , 13 : 5094 – 5107 .
   PubMed Web of Science ®Google Scholar
• Shacter , E and Weitzman , SA . 2002 . Chronic inflammation and cancer . Oncology (Williston Park, NY , 16 : 217 – 226 . 229 discussion 230–212
   PubMed Web of Science ®Google Scholar
• Shibata , Y , Kurita , S , Okugi , H and Yamanaka , H . 2004 . Dramatic remission of hormone refractory prostate cancer achieved with extract of the mushroom, Phellinus linteus . Urologia Internationalis , 73 : 188 – 190 .
   PubMed Web of Science ®Google Scholar
• Shin , JY , Lee , S , Bae , IY , Yoo , SH and Lee , HG . 2007 . Structural and biological study of carboxymethlated Phelinus linteus polysaccharides . J Agricultural and Food Chemistry , 55 : 3368 – 3372 .
   PubMed Web of Science ®Google Scholar
• Sliva , D , Jedinak , A , Kawasaki , J , Harvey , K and Slivova , V . 2008 . Phellinus linteus suppresses growth, angiogenesis and invasive behaviour of breast cancer cells through the inhibition of AKT signalling . British J Cancer , 98 : 1348 – 1356 .
   PubMed Web of Science ®Google Scholar
• Song , KS , Cho , SM , Lee , JH , Kim , HM , Han , SB , Ko , KS and Yoo , ID . 1995 . B‐lymphocyte‐stimulating polysaccharide from mushroom Phellinus linteus . Chemical & Pharmaceutical Bulletin , 43 : 2105 – 2108 .
   PubMed Web of Science ®Google Scholar
• Song , YS , Kim , SH , Sa , JH , Jin , C , Lim , CJ and Park , EH . 2003 . Anti‐angiogenic, antioxidant and xanthine oxidase inhibition activities of the mushroom Phellinus linteus . J Ethnopharmacology , 88 : 113 – 116 .
   PubMed Web of Science ®Google Scholar
• Stacker , SA , Achen , MG , Jussila , L , Baldwin , ME and Alitalo , K . 2002 . Lymphangiogenesis and cancer metastasis . Nature Reviews , 2 : 573 – 583 .
   Web of Science ®Google Scholar
• Ye , M , Hu , D , Tu , L , Zhou , X , Lu , F , Wen , B , Wu , W , Lin , Y , Zhou , Z and Qu , J . 2008 . Involvement of PI3K/Akt signaling pathway in hepatocyte growth factor‐induced migration of uveal melanoma cells . Investigative Ophthalmology & Visual Science , 49 : 497 – 504 .
   PubMed Web of Science ®Google Scholar
• Zhu , T , Guo , J , Collins , L , Kelly , J , Xiao , ZJ , Kim , SH and Chen , CY . 2007 . Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells . British J Cancer , 96 : 583 – 590 .
   PubMed Web of Science ®Google Scholar
• To whom correspondence should be addressed. Tel: +82–53–950–5388; Fax: +82–53–943–6925. E‐mail: [email protected]
   Google Scholar