Differences in the starvation-induced autophagy response in MDA-MB-231 and MCF-7 breast cancer cells

References

• Alers S, Loffler AS, Wesselborg S, Stork B. 2012. Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks. Mol Cell Biol. 32:2–11. doi: 10.1128/MCB.06159-11
   PubMed Web of Science ®Google Scholar
• Amaravadi R, Kimmelman AC, White E. 2016. Recent insights into the function of autophagy in cancer: table 1. Genes Dev. 30:1913–1930. doi: 10.1101/gad.287524.116
   PubMed Web of Science ®Google Scholar
• Barth S, Glick D, Macleod KF. 2010. Autophagy: assays and artifacts. J Pathol. 221:117–124. doi: 10.1002/path.2694
   PubMed Web of Science ®Google Scholar
• Chen N, Debnath J. 2010. Autophagy and tumorigenesis. FEBS Lett. 584:1427–1435. doi: 10.1016/j.febslet.2009.12.034
   PubMed Web of Science ®Google Scholar
• Chen Y, Liu XR, Yin YQ, Lee CJ, Wang FT, Liu HQ, Wu XT, Liu J. 2014. Unravelling the multifaceted roles of ATG proteins to improve cancer therapy. Cell Prolif. 47:105–112. doi: 10.1111/cpr.12095
   PubMed Web of Science ®Google Scholar
• Choi JC, Worman HJ. 2013. Reactivation of autophagy ameliorates LMNA cardiomyopathy. Autophagy. 9:110–111. doi: 10.4161/auto.22403
   PubMed Web of Science ®Google Scholar
• Cianfanelli V, De Zio D, Di Bartolomeo S, Nazio F, Strappazzon F, Cecconi F. 2015. Ambra1 at a glance. J Cell Sci. 128:2003–2008. doi: 10.1242/jcs.168153
   PubMed Web of Science ®Google Scholar
• Cui J, Lu K, Shi Y, Chen B, Tan SH, Gong Z, Shen HM. 2015. Integrated and comparative miRNA analysis of starvation-induced autophagy in mouse embryonic fibroblasts. Gene. 571:194–204. doi: 10.1016/j.gene.2015.06.040
   PubMed Web of Science ®Google Scholar
• de Duve C. 1983. Lysosomes revisited. Eur J Biochem. 137:391–397. doi: 10.1111/j.1432-1033.1983.tb07841.x
   PubMedGoogle Scholar
• Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. 2015. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 136:E359–E386. doi: 10.1002/ijc.29210
   PubMed Web of Science ®Google Scholar
• Funderburk SF, Wang QJ, Yue Z. 2010. The Beclin 1-VPS34 complex – at the crossroads of autophagy and beyond. Trends Cell Biol. 20:355–362. doi: 10.1016/j.tcb.2010.03.002
   PubMed Web of Science ®Google Scholar
• Gu W, Wan D, Qian Q, Yi B, He Z, Gu Y, Wang L, He S, Fimia GM. 2014. Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: pro-survival role of Ambra1. PLoS One. 9:e90151. doi: 10.1371/journal.pone.0090151
   PubMed Web of Science ®Google Scholar
• Guo Q, Liu Z, Jiang L, Hu T, Li D, Liu Y, Liu M, Liang X, Nan K. 2014. Starvation-induced autophagy in cultured non-small cell lung cancer cells. Nan Fang Yi Ke Da Xue Xue Bao. 34:627–630.
   PubMedGoogle Scholar
• He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, et al. 2012. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature. 481:511–515. doi: 10.1038/nature10758
   PubMed Web of Science ®Google Scholar
• Huangfu L, Liang H, Wang G, Su X, Li L, Du Z, Hu M, Dong Y, Bai X, Liu T, et al. 2016. miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG. Oncotarget. 7:4735–4745.
   PubMed Web of Science ®Google Scholar
• Levine B, Kroemer G. 2008. Autophagy in the pathogenesis of disease. Cell. 132:27–42. doi: 10.1016/j.cell.2007.12.018
   PubMed Web of Science ®Google Scholar
• Marinello PC, da Silva TN, Panis C, Neves AF, Machado KL, Borges FH, Guarnier FA, Bernardes SS, de-Freitas-Junior JC, Morgado-Diaz JA, et al. 2016. Mechanism of metformin action in MCF-7 and MDA-MB-231 human breast cancer cells involves oxidative stress generation, DNA damage, and transforming growth factor beta1 induction. Tumour Biol. 37:5337–5346. doi: 10.1007/s13277-015-4395-x
   PubMed Web of Science ®Google Scholar
• Mizushima N. 2010. The role of the ATG1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol. 22:132–139. doi: 10.1016/j.ceb.2009.12.004
   PubMed Web of Science ®Google Scholar
• Mizushima N, Komatsu M. 2011. Autophagy: renovation of cells and tissues. Cell. 147:728–741. doi: 10.1016/j.cell.2011.10.026
   PubMed Web of Science ®Google Scholar
• Mizushima N, Yoshimori T, Levine B. 2010. Methods in mammalian autophagy research. Cell. 140:313–326. doi: 10.1016/j.cell.2010.01.028
   PubMed Web of Science ®Google Scholar
• Mowers EE, Sharifi MN, Macleod KF. 2017. Autophagy in cancer metastasis. Oncogene. 36:1619–1630. doi: 10.1038/onc.2016.333
   PubMed Web of Science ®Google Scholar
• Nardella M, Guglielmi L, Musa C, Iannetti I, Maresca G, Amendola D, Porru M, Carico E, Sessa G, Camerlingo R, et al. 2015. Down-regulation of the lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells. Oncotarget. 6:32821–32840.
   PubMed Web of Science ®Google Scholar
• Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T. 2007. P62/SQSTM1 binds directly to ATG8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem. 282:24131–24145. doi: 10.1074/jbc.M702824200
   PubMed Web of Science ®Google Scholar
• Pfisterer SG, Bakula D, Frickey T, Cezanne A, Brigger D, Tschan MP, Robenek H, Proikas-Cezanne T. 2014. Lipid droplet and early autophagosomal membrane targeting of ATG2A and ATG14L in human tumor cells. J Lipid Res. 55:1267–1278. doi: 10.1194/jlr.M046359
   PubMed Web of Science ®Google Scholar
• Pike LR, Singleton DC, Buffa F, Abramczyk O, Phadwal K, Li JL, Simon AK, Murray JT, Harris AL. 2013. Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival. Biochem J. 449:389–400. doi: 10.1042/BJ20120972
   PubMed Web of Science ®Google Scholar
• Rebecca VW, Amaravadi RK. 2016. Emerging strategies to effectively target autophagy in cancer. Oncogene. 35:1–11. doi: 10.1038/onc.2015.99
   PubMed Web of Science ®Google Scholar
• Shen P, Chen M, He M, Chen L, Song Y, Xiao P, Wan X, Dai F, Pan T, Wang Q. 2016. Inhibition of ERalpha/ERK/P62 cascades induces ‘autophagic switch’ in the estrogen receptor-positive breast cancer cells exposed to gemcitabine. Oncotarget. 7:48501–48516.
   PubMed Web of Science ®Google Scholar
• Tang Y, Wang Y, Kiani MF, Wang B. 2016. Classification, treatment strategy, and associated drug resistance in breast cancer. Clin Breast Cancer. 16:335–343. doi: 10.1016/j.clbc.2016.05.012
   PubMed Web of Science ®Google Scholar
• Wei Y, An Z, Zou Z, Sumpter R, Su M, Zang X, Sinha S, Gaestel M, Levine B. 2015. The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through beclin 1 phosphorylation. Elife. 4.
   Web of Science ®Google Scholar
• White E. 2015. The role for autophagy in cancer. J Clin Invest. 125:42–46. doi: 10.1172/JCI73941
   PubMed Web of Science ®Google Scholar
• Xu DW, Zhang GQ, Wang ZW, Xu XY, Liu TX. 2015. Autophagy in tumorigenesis and cancer treatment. Asian Pac J Cancer Prev. 16:2167–2175. doi: 10.7314/APJCP.2015.16.6.2167
   PubMedGoogle Scholar
• Yamamoto H, Kakuta S, Watanabe TM, Kitamura A, Sekito T, Kondo-Kakuta C, Ichikawa R, Kinjo M, Ohsumi Y. 2012. ATG9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol. 198:219–233. doi: 10.1083/jcb.201202061
   PubMed Web of Science ®Google Scholar
• Zardavas D, Irrthum A, Swanton C, Piccart M. 2015. Clinical management of breast cancer heterogeneity. Nat Rev Clin Oncol. 12:381–394. doi: 10.1038/nrclinonc.2015.73
   PubMed Web of Science ®Google Scholar
• Zarzynska JM. 2014. The importance of autophagy regulation in breast cancer development and treatment. Biomed Res Int. 2014:1–9. doi: 10.1155/2014/710345
   Web of Science ®Google Scholar
• Zhou Y, Rucker EB, 3rd, Zhou BP. 2016. Autophagy regulation in the development and treatment of breast cancer. Acta Biochim Biophys Sin (Shanghai). 48:60–74. doi: 10.1093/abbs/gmw063
   PubMed Web of Science ®Google Scholar