Estradiol treatment increases M2-like visceral adipose tissue macrophages in obese ovariectomized mice regardless of its anorectic action

References

• Amano SU, Cohen JL, Vangala P, Tencerova M, Nicoloro SM, Yawe JC, Shen Y, Czech MP, Aouadi M. 2014. Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation. Cell Metab. 19(1):162–171. doi: 10.1016/j.cmet.2013.11.017
   PubMed Web of Science ®Google Scholar
• Barton M, Meyer MR. 2009. Postmenopausal hypertension: mechanisms and therapy. Hypertension. 54(1):11–18. doi: 10.1161/HYPERTENSIONAHA.108.120022
   PubMed Web of Science ®Google Scholar
• Bourlier V, Zakaroff-Girard A, Miranville A, De Barros S, Maumus M, Sengenes C, Galitzky J, Lafontan M, Karpe F, Frayn KN, et al. 2008. Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation. 117(6):806–815. doi: 10.1161/CIRCULATIONAHA.107.724096
   PubMed Web of Science ®Google Scholar
• Christin-Maitre S. 2017. Use of hormone replacement in females with endocrine disorders. Horm Res Paediatr. 87(4):215–223. eng. doi: 10.1159/000457125
   PubMed Web of Science ®Google Scholar
• Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, Wang S, Fortier M, Greenberg AS, Obin MS. 2005. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res. 46(11):2347–2355. doi: 10.1194/jlr.M500294-JLR200
   PubMed Web of Science ®Google Scholar
• Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, et al. 2007. Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med. 13(1):89–94. doi: 10.1038/nm1525
   PubMed Web of Science ®Google Scholar
• Gericke M, Weyer U, Braune J, Bechmann I, Eilers J. 2015. A method for long-term live imaging of tissue macrophages in adipose tissue explants. Am J Physiol - Endocrinol Metab. 308(11):E1023–E1033. doi: 10.1152/ajpendo.00075.2015
   PubMed Web of Science ®Google Scholar
• Hill DA, Lim HW, Kim YH, Ho WY, Foong YH, Nelson VL, Nguyen HCB, Chegireddy K, Kim J, Habertheuer A, et al. 2018. Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue. Proc Natl Acad Sci U S A. 115(22):E5096–E5105. doi: 10.1073/pnas.1802611115
   PubMed Web of Science ®Google Scholar
• Hotamisligil GS. 2006. Inflammation and metabolic disorders. Nature. 444(7121):860–867. eng. doi: 10.1038/nature05485
   PubMed Web of Science ®Google Scholar
• Hotamisligil GS, Shargill NS, Spiegelman BM. 1993. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 259(5091):87–91. doi: 10.1126/science.7678183
   PubMed Web of Science ®Google Scholar
• Ishikawa A, Wada T, Nishimura S, Ito T, Okekawa A, Onogi Y, Watanabe E, Sameshima A, Tanaka T, Tsuneki H, et al. 2020. Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice. PLoS One. 15(4):e0230885. doi: 10.1371/journal.pone.0230885
   PubMed Web of Science ®Google Scholar
• Ito A, Suganami T, Yamauchi A, Degawa-Yamauchi M, Tanaka M, Kouyama R, Kobayashi Y, Nitta N, Yasuda K, Hirata Y, et al. 2008. Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue. J Biol Chem. 283(51):35715–35723. doi: 10.1074/jbc.M804220200
   PubMed Web of Science ®Google Scholar
• Jang HS, Kim K, Lee MR, Kim SH, Choi JH, Park MJ. 2020. Treatment of growth hormone attenuates hepatic steatosis in hyperlipidemic mice via downregulation of hepatic CD36 expression. Animal Cells Syst (Seoul). 24(3):151–159. doi: 10.1080/19768354.2020.1778080
   PubMed Web of Science ®Google Scholar
• Jürimäe J, Hills AP, Jürimäe T. 2010. Cytokines, growth mediators, and physical activity in children during puberty. Basel: Karger. (Medicine and sport science,; 55).
   Google Scholar
• Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR. 2007. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes. 56(1):16–23. doi: 10.2337/db06-1076
   PubMed Web of Science ®Google Scholar
• Luukkainen A, Puan KJ, Yusof N, Lee B, Tan KS, Liu J, Yan Y, Toppila-Salmi S, Renkonen R, Chow VT, et al. 2018. A co-culture model of PBMC and stem cell derived human nasal epithelium reveals rapid activation of NK and innate T cells upon influenza a virus infection of the nasal epithelium. Front Immunol. 9:2514. doi: 10.3389/fimmu.2018.02514
   PubMed Web of Science ®Google Scholar
• Ohashi K, Parker JL, Ouchi N, Higuchi A, Vita JA, Gokce N, Pedersen AA, Kalthoff C, Tullin S, Sams A, et al. 2010. Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J Biol Chem. 285(9):6153–6160. doi: 10.1074/jbc.M109.088708
   PubMed Web of Science ®Google Scholar
• Parker R, Weston CJ, Miao Z, Corbett C, Armstrong MJ, Ertl L, Ebsworth K, Walters MJ, Baumart T, Newland D, et al. 2018. CC chemokine receptor 2 promotes recruitment of myeloid cells associated with insulin resistance in nonalcoholic fatty liver disease. Am J Physiol-Gastrointest Liver Physiol. 314(4):G483–G493. doi: 10.1152/ajpgi.00213.2017
   PubMed Web of Science ®Google Scholar
• Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG. 2008. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab. 8(4):301–309. doi: 10.1016/j.cmet.2008.08.015
   PubMed Web of Science ®Google Scholar
• Pekala P, Kawakami M, Vine W, Lane MD, Cerami A. 1983. Studies of insulin resistance in adipocytes induced by macrophage mediator. J Exp Med. 157(4):1360–1365. doi: 10.1084/jem.157.4.1360
   PubMed Web of Science ®Google Scholar
• Pepe G, Braga D, Renzi TA, Villa A, Bolego C, D'Avila F, Barlassina C, Maggi A, Locati M, Vegeto E. 2017. Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge. Sci Rep. 7:44270. doi: 10.1038/srep44270
   PubMed Web of Science ®Google Scholar
• Regitz-Zagrosek V, Lehmkuhl E, Weickert MO. 2006. Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clin Res Cardiol. 95(3):136–147. doi: 10.1007/s00392-006-0351-5
   PubMed Web of Science ®Google Scholar
• Rogers NH, Perfield JW, 2nd, Strissel KJ, Obin MS, Greenberg AS. 2009. Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology. 150(5):2161–2168. doi: 10.1210/en.2008-1405
   PubMed Web of Science ®Google Scholar
• Russo L, Lumeng CN. 2018. Properties and functions of adipose tissue macrophages in obesity. Immunology. 155(4):407–417. eng. doi: 10.1111/imm.13002
   PubMed Web of Science ®Google Scholar
• Shi H, Kumar SP, Liu X. 2013. G protein-coupled estrogen receptor in energy homeostasis and obesity pathogenesis. Prog Mol Biol Transl Sci. 114:193–250. doi: 10.1016/B978-0-12-386933-3.00006-6
   PubMed Web of Science ®Google Scholar
• Sul OJ, Hyun HJ, Rajasekaran M, Suh JH, Choi HS. 2021. Estrogen enhances browning in adipose tissue by M2 macrophage polarization via heme oxygenase-1. J Cell Physiol. 236(3):1875–1888. doi: 10.1002/jcp.29971
   PubMed Web of Science ®Google Scholar
• Toniolo A, Fadini GP, Tedesco S, Cappellari R, Vegeto E, Maggi A, Avogaro A, Bolego C, Cignarella A. 2015. Alternative activation of human macrophages is rescued by estrogen treatment in vitro and impaired by menopausal status. J Clin Endocrinol Metab. 100(1):E50–E58. doi: 10.1210/jc.2014-2751
   PubMed Web of Science ®Google Scholar
• Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW, Jr. 2003. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 112(12):1796–1808. doi: 10.1172/JCI200319246
   PubMed Web of Science ®Google Scholar
• Wentworth JM, Naselli G, Brown WA, Doyle L, Phipson B, Smyth GK, Wabitsch M, O'Brien PE, Harrison LC. 2010. Pro-inflammatory CD11c + CD206 + adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes. 59(7):1648–1656. doi: 10.2337/db09-0287
   PubMed Web of Science ®Google Scholar
• Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, et al. 2003. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 112(12):1821–1830. eng. doi: 10.1172/JCI200319451
   PubMed Web of Science ®Google Scholar
• Zeyda M, Farmer D, Todoric J, Aszmann O, Speiser M, Gyori G, Zlabinger GJ, Stulnig TM. 2007. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes. 31(9):1420–1428. doi: 10.1038/sj.ijo.0803632
   PubMed Web of Science ®Google Scholar