Crosstalk between endoplasmic reticulum stress response and autophagy in human diseases

References

• Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Bock J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, et al. 2013. Paneth cells as a site of origin for intestinal inflammation. Nature. 503(7475):272–276.
   PubMed Web of Science ®Google Scholar
• Alam R, Kabir MF, Kim HR, HJ C. 2022. Canonical and noncanonical ER Stress-mediated autophagy is a bite the bullet in view of cancer therapy. Cells. 11(23):3773.
   PubMed Web of Science ®Google Scholar
• Andhavarapu S, Mubariz F, Arvas M, Bever C, Makar TK. 2019. Interplay between ER stress and autophagy: a possible mechanism in multiple sclerosis pathology. Exp Mol Pathol. 108:183–190.
   PubMed Web of Science ®Google Scholar
• Baek SH, Kim KI. 2017. Epigenetic control of autophagy: nuclear events gain more attention. Mol Cell. 65(5):781–785.
   PubMed Web of Science ®Google Scholar
• B'Chir W, Maurin AC, Carraro V, Averous J, Jousse C, Muranishi Y, Parry L, Stepien G, Fafournoux P, Bruhat A. 2013. The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression. Nucleic Acids Res. 41(16):7683–7699.
   PubMed Web of Science ®Google Scholar
• Berridge MJ. 2002. The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium. 32(5-6):235–249.
   PubMed Web of Science ®Google Scholar
• Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D. 2000. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol. 2(6):326.
   PubMed Web of Science ®Google Scholar
• Bhardwaj M, Leli NM, Koumenis C, Amaravadi RK. 2020. Regulation of autophagy by canonical and noncanonical ER stress responses. Semin Cancer Biol. 66:116–128.
   PubMed Web of Science ®Google Scholar
• Brugarolas J, Lei K, Hurley RL, Manning BD, Reiling JH, Hafen E, Witters LA, Ellisen LW, Kaelin WG. 2004. Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev. 18(23):2893–2904.
   PubMed Web of Science ®Google Scholar
• Chang NC. 2020. Autophagy and stem cells: self-eating for self-renewal. Front Cell Dev Biol. 8:138.
   PubMed Web of Science ®Google Scholar
• Chen Y, Klionsky DJ. 2011. The regulation of autophagy - unanswered questions. J Cell Sci. 124(Pt 2):161–170.
   PubMed Web of Science ®Google Scholar
• Chevet E, Cameron PH, Pelletier MF, Thomas DY, Bergeron JJ. 2001. The endoplasmic reticulum: integration of protein folding, quality control, signaling and degradation. Curr Opin Struct Biol. 11(1):120–124.
   PubMed Web of Science ®Google Scholar
• Chipurupalli S, Samavedam U, Robinson N. 2021. Crosstalk between ER Stress, autophagy and inflammation. Front Med (Lausanne). 8:758311.
   PubMed Web of Science ®Google Scholar
• Deegan S, Saveljeva S, Gorman AM, Samali A. 2013. Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress. Cell Mol Life Sci. 70(14):2425–2441.
   PubMed Web of Science ®Google Scholar
• Eizirik DL, Cardozo AK, Cnop M. 2008. The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev. 29(1):42–61.
   PubMed Web of Science ®Google Scholar
• Esmaeili Y, Yarjanli Z, Pakniya F, Bidram E, Los MJ, Eshraghi M, Klionsky DJ, Ghavami S, Zarrabi A. 2022. Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment. J Control Release. 345:147–175.
   PubMed Web of Science ®Google Scholar
• Evans CS, Holzbaur ELF. 2019. Autophagy and mitophagy in ALS. Neurobiol Dis. 122:35–40.
   PubMed Web of Science ®Google Scholar
• Flamment M, Hajduch E, Ferre P, Foufelle F. 2012. New insights into ER stress-induced insulin resistance. Trends Endocrinol Metab. 23(8):381–390.
   PubMed Web of Science ®Google Scholar
• Gade P, Ramachandran G, Maachani UB, Rizzo MA, Okada T, Prywes R, Cross AS, Mori K, Kalvakolanu DV. 2012. An IFN-γ–stimulated ATF6–C/EBP-β–signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy. Proc Natl Acad Sci U S A. 109(26):10316–10321.
   PubMed Web of Science ®Google Scholar
• Glick D, Barth S, Macleod KF. 2010. Autophagy: cellular and molecular mechanisms. J Pathol. 221(1):3–12.
   PubMed Web of Science ®Google Scholar
• Grumati P, Dikic I, Stolz A. 2018. ER-phagy at a glance. J Cell Sci. 131(17):jcs217364.
   PubMed Web of Science ®Google Scholar
• Ichimura Y, Waguri S, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, et al. 2013. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell. 51(5):618–631.
   PubMed Web of Science ®Google Scholar
• Ji GR, Yu NC, Xue X, Li ZG. 2015. PERK-mediated autophagy in osteosarcoma cells resists ER stress-induced cell apoptosis. Int J Biol Sci. 11(7):803–812.
   PubMed Web of Science ®Google Scholar
• Kleizen B, Braakman I. 2004. Protein folding and quality control in the endoplasmic reticulum. Curr Opin Cell Biol. 16(4):343–349.
   PubMed Web of Science ®Google Scholar
• Kwon J, Lee Y, Jeong JH, Ryu JH, Kim KI. 2020. Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death. Biochem Biophys Res Commun. 526(2):300–305.
   PubMed Web of Science ®Google Scholar
• Lee Y, Kwon J, Jeong JH, Ryu JH, Kim KI. 2022. Kazinol C from Broussonetia kazinoki stimulates autophagy via endoplasmic reticulum stress-mediated signaling. Anim Cells Syst (Seoul). 26(1):28–36.
   PubMed Web of Science ®Google Scholar
• Lin Y, Jiang M, Chen W, Zhao T, Wei Y. 2019. Cancer and ER stress: mutual crosstalk between autophagy, oxidative stress and inflammatory response. Biomed Pharmacother. 118:109249.
   PubMed Web of Science ®Google Scholar
• Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, et al. 2014. Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma. J Clin Invest. 124(3):1406–1417.
   PubMed Web of Science ®Google Scholar
• Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, et al. 2013. XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. J Biol Chem. 288(2):859–872.
   PubMed Web of Science ®Google Scholar
• Medchalmi S, Tare P, Sayyad Z, Swarup G. 2021. A glaucoma- and ALS-associated mutant of OPTN induces neuronal cell death dependent on Tbk1 activity, autophagy and ER stress. FEBS J. 288(15):4576–4595.
   PubMed Web of Science ®Google Scholar
• Meng XX, Yao M, Zhang XD, Xu HX, Dong Q. 2015. ER stress-induced autophagy in melanoma. Clin Exp Pharmacol Physiol. 42(8):811–816.
   PubMed Web of Science ®Google Scholar
• Mizushima N, Komatsu M. 2011. Autophagy: renovation of cells and tissues. Cell. 147(4):728–741.
   PubMed Web of Science ®Google Scholar
• Mizushima N, Yoshimori T, Ohsumi Y. 2011. The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol. 27:107–132.
   PubMed Web of Science ®Google Scholar
• Mochida K, Nakatogawa H. 2022. ER-phagy: selective autophagy of the endoplasmic reticulum. EMBO Rep. 23(8):e55192.
   PubMed Web of Science ®Google Scholar
• Munro S, Pelham HR. 1986. An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell. 46(2):291–300.
   PubMed Web of Science ®Google Scholar
• Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. 2009. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol. 10(7):458–467.
   PubMed Web of Science ®Google Scholar
• Nijholt DA, de Graaf TR, van Haastert ES, Oliveira AO, Berkers CR, Zwart R, Ovaa H, Baas F, Hoozemans JJ, Scheper W. 2011. Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease. Cell Death Differ. 18(6):1071–1081.
   PubMed Web of Science ®Google Scholar
• Orenstein SJ, Cuervo AM. 2010. Chaperone-mediated autophagy: molecular mechanisms and physiological relevance. Semin Cell Dev Biol. 21(7):719–726.
   PubMed Web of Science ®Google Scholar
• Park SJ, Li C, Chen YM. 2021. Endoplasmic reticulum calcium homeostasis in kidney disease: pathogenesis and therapeutic targets. Am J Pathol. 191(2):256–265.
   PubMed Web of Science ®Google Scholar
• Rashid HO, Yadav RK, Kim HR, HJ C. 2015. ER stress: Autophagy induction, inhibition and selection. Autophagy. 11(11):1956–1977.
   PubMed Web of Science ®Google Scholar
• Salih DA, Brunet A. 2008. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr Opin Cell Biol. 20(2):126–136.
   PubMed Web of Science ®Google Scholar
• Saucedo LJ, Gao X, Chiarelli DA, Li L, Pan D, Edgar BA. 2003. Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat Cell Biol. 5(6):566–571.
   PubMed Web of Science ®Google Scholar
• Schonthal AH. 2012. Endoplasmic reticulum stress: its role in disease and novel prospects for therapy. Scientifica (Cairo). 2012:857516.
   PubMedGoogle Scholar
• Senft D, Ronai ZA. 2015. UPR, autophagy, and mitochondria crosstalk underlies the ER stress response. Trends Biochem Sci. 40(3):141–148.
   PubMed Web of Science ®Google Scholar
• Shang D, Wang L, Klionsky DJ, Cheng H, Zhou R. 2021. Sex differences in autophagy-mediated diseases: toward precision medicine. Autophagy. 17(5):1065–1076.
   PubMed Web of Science ®Google Scholar
• Shen J, Chen X, Hendershot L, Prywes R. 2002. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev Cell. 3(1):99–111.
   PubMed Web of Science ®Google Scholar
• Shin HR, Kim H, Kim KI, Baek SH. 2016. Epigenetic and transcriptional regulation of autophagy. Autophagy. 12(11):2248–2249.
   PubMed Web of Science ®Google Scholar
• Smith M, Wilkinson S. 2017. ER homeostasis and autophagy. Essays Biochem. 61(6):625–635.
   PubMed Web of Science ®Google Scholar
• Song S, Tan J, Miao Y, Zhang Q. 2018. Crosstalk of ER stress-mediated autophagy and ER-phagy: Involvement of UPR and the core autophagy machinery. J Cell Physiol. 233(5):3867–3874.
   PubMed Web of Science ®Google Scholar
• Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC. 2011. The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. Mol Biol Cell. 22(22):4390–4405.
   PubMed Web of Science ®Google Scholar
• Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, et al. 2012. Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Hum Mol Genet. 21(10):2245–2262.
   PubMed Web of Science ®Google Scholar
• Wang B, Su CJ, Liu TT, Zhou Y, Feng Y, Huang Y, Liu X, Wang ZH, Chen LH, Luo WF, et al. 2018. The neuroprotection of low-dose morphine in cellular and animal models of Parkinson's disease through ameliorating endoplasmic reticulum (ER) stress and activating autophagy. Front Mol Neurosci. 11:120.
   PubMed Web of Science ®Google Scholar
• Wang CW, Klionsky DJ. 2003. The molecular mechanism of autophagy. Mol Med. 9(3-4):65–76.
   PubMed Web of Science ®Google Scholar
• Wang X, Zhou S, Ding X, Ma M, Zhang J, Zhou Y, Wu E, Teng J. 2015. Activation of ER stress and autophagy induced by TDP-43 A315 T as pathogenic mechanism and the corresponding histological changes in skin as potential biomarker for ALS with the mutation. Int J Biol Sci. 11(10):1140–1149.
   PubMed Web of Science ®Google Scholar
• Wang Z, Yin F, Xu J, Zhang T, Wang G, Mao M, Wang Z, Sun W, Han J, Yang M, et al. 2019. CYT997(Lexibulin) induces apoptosis and autophagy through the activation of mutually reinforced ER stress and ROS in osteosarcoma. J Exp Clin Cancer Res. 38(1):44.
   PubMedGoogle Scholar
• Wu R, Zhang QH, Lu YJ, Ren K, Yi GH. 2015. Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases. DNA Cell Biol. 34(1):6–18.
   PubMed Web of Science ®Google Scholar
• Yang M, Luo S, Wang X, Li C, Yang J, Zhu X, Xiao L, Sun L. 2021. ER-Phagy: a new regulator of ER homeostasis. Front Cell Dev Biol. 9:684526.
   PubMed Web of Science ®Google Scholar
• Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A. 2009. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep. 10(3):285–292.
   PubMed Web of Science ®Google Scholar
• Zeng M, Sang W, Chen S, Chen R, Zhang H, Xue F, Li Z, Liu Y, Gong Y, Zhang H, et al. 2017. 4-PBA inhibits LPS-induced inflammation through regulating ER stress and autophagy in acute lung injury models. Toxicol Lett. 271:26–37.
   PubMed Web of Science ®Google Scholar
• Zhang JY, Ma S, Liu X, Du Y, Zhu X, Liu Y, Wu X. 2022. Activating transcription factor 6 regulates cystathionine to increase autophagy and restore memory in Alzheimer's disease model mice. Biochem Biophys Res Commun. 615:109–115.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Shen Y, Luo H, Zhang F, Peng D, Jing L, Wu Y, Xia X, Song Y, Li W, et al. 2018. MANF protects dopamine neurons and locomotion defects from a human α-synuclein induced Parkinson's disease model in C. elegans by regulating ER stress and autophagy pathways. Exp Neurol. 308:59–71.
   PubMed Web of Science ®Google Scholar
• Zhao L, Zhao J, Zhong K, Tong A, Jia D. 2022. Targeted protein degradation: mechanisms, strategies and application. Signal Transduct Target Ther. 7(1):113.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Li X, Cai MY, Ma K, Yang J, Zhou J, Fu W, Wei FZ, Wang L, Xie D, et al. 2013. XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells. Cell Res. 23(4):491–507.
   PubMed Web of Science ®Google Scholar
• Zhou Z, Wang Q, Michalak M. 2021. Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress. Anim Cells Syst (Seoul). 25(6):347–357.
   PubMed Web of Science ®Google Scholar